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Disclosery

MBX MBX BIOSCIENCES INC

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Stock (common), issuer CIK 1776111

165 managers (173 13F filers) reported a position in MBX shares at 2026-06-30, 55,478,890 shares in all. 36 filers opened a position and 20 filers sold out during the quarter.

Managers
165
13F filers
173
New
36
Added
64
Reduced
49
Sold out
20
Shares held by filers
55,478,890

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Frazier Life Sciences Management, L.P.6,652,013$367M8%013F-HRTimeline
FMR LLCin group FMR LLC5,322,885$294M0.01%+2,386,20113F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…4,977,523$275M0.05%+1,785,69913F-HRTimelineGroup
NEA Management Company, LLC3,614,486$200M12.56%013F-HRTimeline
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC3,428,736$189M3.58%-209,15113F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.3,323,672$183M<0.01%+382,26613F-HRTimelineGroup
Paradigm Biocapital Advisors LPin group Paradigm Biocapital Advisors …2,508,015$138M2.59%new13F-HRTimelineGroup
NVP ASSOCIATES, LLC2,136,335$118M35.93%013F-HRTimeline
VANGUARD GROUP INCgroup of 6 filers holding2,065,358$114M+87,434Timeline
Deep Track Capital, LP1,732,569$95.6M1.41%-1,025,00013F-HRTimeline
Polar Capital Holdings Plcin group Polar Capital Holdings Plc1,608,514$88.8M0.25%-13,67213F-HRTimelineGroup
Aaron Wealth Advisors LLC1,167,799$64.5M3.27%-37713F-HRTimeline
Driehaus Capital Management LLC1,056,579$58.3M0.34%+38,36713F-HRTimeline
Kynam Capital Management, LP934,799$51.6M2.85%013F-HRTimeline
Woodline Partners LP900,092$49.7M0.15%+2913F-HRTimeline
EVENTIDE ASSET MANAGEMENT, LLC873,492$48.2M0.64%-16,50813F-HRTimeline
STATE STREET CORPin group STATE STREET CORP864,466$47.7M<0.01%+77,25813F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/814,807$45M<0.01%-214,20013F-HRTimeline
Parkman Healthcare Partners LLC800,173$44.2M4.54%+13613F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC773,072$42.7M<0.01%+102,68713F-HRTimelineGroup
BRAIDWELL LP710,880$39.2M1.45%-781,58713F-HRTimeline
TCG Crossover Management, LLC650,000$35.9M0.86%013F-HRTimeline
Cormorant Asset Management, LP550,000$30.4M1.56%-570,00013F-HRTimeline
Soleus Capital Management, L.P.515,279$28.4M0.98%+336,38213F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC459,005$25.3M<0.01%+1,06013F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP401,885$22.2M0.02%+339,18213F-HRTimelineGroup
EcoR1 Capital, LLC388,500$21.4M1.06%-388,50013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/298,927$16.5M<0.01%+270,17713F-HRTimelineGroup
Rock Springs Capital Management LP298,218$16.5M0.8%+10,25113F-HRTimeline
UBS Group AGgroup of 2 filers holding294,091$16.2M-60,061Timeline
Candriam S.C.A.289,893$16M0.07%-4,48113F-HRTimeline
Opaleye Management Inc.260,000$14.4M1.3%013F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources252,665$13.9M<0.01%new13F-HRTimelineGroup
Schonfeld Strategic Advisors LLC248,670$13.7M0.07%+124,85613F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY248,558$13.7M<0.01%+216,99613F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP246,678$13.6M<0.01%+36,10313F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP233,700$12.9M<0.01%+186,94713F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co233,095$12.9M<0.01%+18,18713F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC226,151$12.5M0.01%-338,26413F-HRTimelineGroup
Tetragon Partners GP Ltdin group Tetragon Partners GP Ltd203,543$11.2M1.83%+58,06313F-HRTimelineGroup
Caligan Partners LP200,000$11M0.53%-648,59013F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.182,767$10.1M0.01%-106,12213F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO139,611$7.52M<0.01%-7,44613F-HRTimelineGroup
KVP Capital Advisors, LP121,524$6.71M4.92%013F-HRTimeline
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP113,475$6.26M<0.01%-1,60013F-HRTimelineGroup
Burkehill Global Management, LP100,000$5.52M0.2%013F-HRTimeline
Nuveen, LLCin group TIAA98,733$5.45M<0.01%+16,94113F-HRTimelineGroup
TD Asset Management Inc95,598$5.28M<0.01%-20,40013F-HRTimeline
Elmind Capital, LP91,000$5.02M1.26%-120,00013F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp88,927$4.91M<0.01%+8,70513F-HRTimelineGroup
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC88,045$4.86M0.01%new13F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC87,854$4.85M<0.01%+76,01613F-HRTimelineGroup
Affinity Asset Advisors, LLC75,000$4.14M0.2%-75,00013F-HRTimeline
PFM Health Sciences, LP70,971$3.92M0.34%-92313F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC70,353$3.88M0.07%-137,69613F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …66,112$3.65M<0.01%-24,52213F-HRTimelineGroup
MOORE CAPITAL MANAGEMENT, LP64,893$3.58M0.08%new13F-HRTimeline
Rhenman & Partners Asset Management AB62,000$3.42M0.32%new13F-HRTimeline
Invesco Ltd.in group Invesco Ltd.50,678$2.8M<0.01%+23,15313F-HRTimelineGroup
ALPS ADVISORS INC48,012$2.65M0.01%+11,46213F-HRTimeline
PLATINUM INVESTMENT MANAGEMENT LTD43,597$2.41M0.59%013F-HRTimeline
Swiss National Bank42,900$2.37M<0.01%-1,50013F-HRTimeline
Ensign Peak Advisors, Inc42,156$2.33M<0.01%new13F-HRTimeline
ALGERT GLOBAL LLC42,070$2.32M0.03%+6,05013F-HRTimeline
Creative Planningin group Creative Planning39,524$2.18M<0.01%+3,55413F-HRTimelineGroup
RHUMBLINE ADVISERS37,196$2.05M<0.01%+3,32513F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\31,693$1.75M<0.01%+8,74313F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding30,484$1.68M+20,997Timeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN28,313$1.56M<0.01%+17,55113F-HRTimelineGroup
EXCHANGE TRADED CONCEPTS, LLC27,421$1.51M0.01%-6,84313F-HR/ATimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC26,132$1.44M<0.01%new13F-HRTimelineGroup
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …25,800$1.42M<0.01%new13F-HRTimelineGroup
TEACHERS RETIREMENT SYSTEM OF THE STATE…25,377$1.4M0.01%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC25,122$1.39M<0.01%+11,62313F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…23,376$1.29M<0.01%+61113F-HR/ATimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC22,680$1.25M<0.01%+13,95413F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC22,591$1.25M<0.01%-4,79613F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc21,583$1.19M<0.01%+2,22513F-HRTimelineGroup
Cerity Partners LLCin group Cerity Partners LLC20,997$1.16M<0.01%-16613F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…18,250$1.01M<0.01%+2,23213F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…18,162$1M<0.01%+14,30613F-HRTimelineGroup
Koa Wealth Management, LLC17,113$945K0.64%-80013F-HRTimeline
ALLIANCEBERNSTEIN L.P.31,000$925K<0.01%+50013F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding16,421$906K+754Timeline
STATE OF WISCONSIN INVESTMENT BOARD15,971$882K<0.01%-3,29113F-HRTimeline
OPTIMIZE FINANCIAL INC.14,458$798K0.29%-5013F-HRTimeline
Sound Capital Solutions LLC14,458$798K0.19%13F-HRTimeline
DAFNA Capital Management LLC11,809$652K0.12%-163,65613F-HRTimeline
HighVista Strategies LLC11,634$642K0.15%+16213F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND11,000$607K<0.01%+2,00013F-HRTimeline
Jupiter Topco LLCin group Janus Henderson10,300$568K<0.01%13F-HRTimelineGroup
FRED ALGER MANAGEMENT, LLCin group FRED ALGER MANAGEMENT, LLC9,877$545K<0.01%new13F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS9,860$544K<0.01%-52413F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…9,777$540K<0.01%new13F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…9,215$509K0.12%+8413F-HRTimelineGroup
China Universal Asset Management Co., L…9,175$506K0.03%+1,20713F-HRTimeline
Police & Firemen's Retirement System of…9,154$505K<0.01%+1,63413F-HRTimeline
PROFUND ADVISORS LLC8,812$486K0.01%+42413F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…8,602$475K0.01%new13F-HRTimelineGroup
ACT CAPITAL MANAGEMENT, LLC8,000$442K0.29%-1,00013F-HRTimeline
DNB Asset Management ASin group DNB Asset Management AS7,793$430K<0.01%new13F-HRTimelineGroup
AXQ CAPITAL, LP7,757$428K0.05%new13F-HRTimeline
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…6,913$382K<0.01%-76013F-HRTimelineGroup
Quantinno Capital Management LP6,497$359K<0.01%new13F-HRTimeline
Rafferty Asset Management, LLC6,410$354K<0.01%new13F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd6,392$353K<0.01%-46,81813F-HRTimelineGroup
SG Americas Securities, LLC6,245$345K<0.01%+2,85913F-HRTimeline
Seven Fleet Capital Management LP6,000$331K0.05%new13F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC5,951$328K<0.01%-89313F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM5,899$326K<0.01%new13F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO5,868$324K<0.01%-3,12113F-HRTimelineGroup
ProShare Advisors LLC5,622$310K<0.01%new13F-HRTimeline
Blackstone Inc.in group Blackstone Inc.5,533$305K<0.01%new13F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
GROUP ONE TRADING LLC5,231$289K0.01%-1,02013F-HRTimeline
CANADA PENSION PLAN INVESTMENT BOARD5,200$287K<0.01%-5,70013F-HRTimeline
Tidal Investments LLCin group Tidal Investments LLC5,010$277K<0.01%-3,86713F-HRTimelineGroup
Tema ETFs LLC5,010$277K0.01%-3,86713F-HRTimeline
KLP KAPITALFORVALTNING AS4,900$270K<0.01%013F-HRTimeline
Verdad Advisers, LP4,574$252K0.24%new13F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…4,098$226K<0.01%new13F-HRTimelineGroup
Goelzer Investment Management, Inc.4,000$221K0.01%-160,17213F-HRTimeline
Quantbot Technologies LP3,855$213K0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…3,651$202K<0.01%+2,24013F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…2,817$155K<0.01%+50513F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…2,086$115K<0.01%+1,61613F-HRTimeline
NISA INVESTMENT ADVISORS, LLC2,013$111K<0.01%+42113F-HRTimeline
STRS OHIO2,000$110K<0.01%+40013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA1,464$81K<0.01%+71313F-HRTimelineGroup
SIMPLEX TRADING, LLC1,327$73.2K<0.01%+2013F-HRTimeline
State of Wyoming1,055$58.2K0.01%new13F-HRTimeline
GF FUND MANAGEMENT CO. LTD.952$52.5K<0.01%-5713F-HRTimeline
KBC Group NVin group KBC Group NV810$45K<0.01%013F-HRTimelineGroup
Kemnay Advisory Services Inc.321$17.7K<0.01%new13F-HRTimeline
GAMMA Investing LLC304$16.8K<0.01%+513F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.282$15.6K<0.01%+1313F-HRTimelineGroup
Arax Advisory Partners279$15.4K<0.01%new13F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…224$12.4K<0.01%-3,00013F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…207$11.4K<0.01%013F-HRTimelineGroup
FIL Ltdin group FIL Ltd178$9.83K<0.01%013F-HRTimelineGroup
Aster Capital Management (DIFC) Ltd172$9.49K<0.01%new13F-HR/ATimeline
Integrated Wealth Concepts LLC171$9.44K<0.01%new13F-HRTimeline
Physician Wealth Advisors, Inc.121$6.68K<0.01%+1213F-HRTimeline
Sterling Capital Management LLC109$6.02K<0.01%-84013F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\108$5.96K<0.01%-17613F-HRTimelineGroup
J.Safra Asset Management Corp85$4.69K<0.01%new13F-HRTimeline
Parallel Advisors, LLC79$4.36K<0.01%+1813F-HRTimeline
SIGNATUREFD, LLC78$4.31K<0.01%-10113F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP80$4.18K<0.01%013F-HRTimelineGroup
Keating Financial Advisory Services, In…54$2.98K<0.01%+3813F-HRTimeline
Larson Financial Group LLC49$2.71K<0.01%013F-HRTimeline
Allworth Financial LP48$2.65K<0.01%-2213F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…48$2.65K<0.01%+2313F-HRTimelineGroup
ROTHSCHILD INVESTMENT LLC39$2.15K<0.01%+1513F-HRTimeline
Bare Financial Services, Inc34$1.88K<0.01%new13F-HRTimeline
Cornerstone Financial Management LLC34$1.88K<0.01%013F-HR/ATimeline
Global Retirement Partners, LLC19$1.05K<0.01%13F-HRTimeline
Fortitude Family Office, LLC19$1.05K<0.01%013F-HRTimeline
Covestor Ltd10$1K<0.01%+713F-HRTimeline
Quarry LP18$994<0.01%new13F-HRTimeline
Essential Partners LLC15$828<0.01%013F-HRTimeline
Silver Grove Financial Group, Inc.13$718<0.01%new13F-HRTimeline
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/11$607<0.01%new13F-HRTimelineGroup
Farther Finance Advisors, LLC9$497<0.01%013F-HRTimeline
SJS Investment Consulting Inc.2$111<0.01%new13F-HRTimeline
Hughes Financial Services, LLC1$55<0.01%new13F-HRTimeline