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Disclosery

PRME PRIME MEDICINE INC

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COM (common), issuer CIK 1894562

179 managers (187 13F filers) reported a position in PRME shares at 2026-06-30, 106,647,979 shares in all. 22 filers opened a position and 23 filers sold out during the quarter.

Managers
179
13F filers
187
New
22
Added
64
Reduced
67
Sold out
23
Shares held by filers
106,647,979

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Alphabet Inc.in group Alphabet Inc.16,562,498$61.1M0.06%013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.9,602,041$35.4M<0.01%+1,100,33313F-HRTimelineGroup
ARK Investment Management LLC8,348,746$30.8M0.2%+2,101,91913F-HRTimeline
STATE STREET CORPin group STATE STREET CORP7,576,460$28M<0.01%+1,231,33513F-HRTimelineGroup
VANGUARD GROUP INCgroup of 8 filers holding6,398,596$23.6M+193,526Timeline
T. Rowe Price Investment Management, In…5,237,332$19.3M0.01%-244,56113F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management3,969,082$14.6M0.03%-154,28313F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC3,430,518$12.7M<0.01%+2,460,09313F-HRTimelineGroup
Casdin Capital, LLC3,167,175$11.7M0.58%013F-HRTimeline
Woodline Partners LP3,003,904$11.1M0.03%+59113F-HRTimeline
UBS Group AGgroup of 2 filers holding2,879,989$10.6M-93,729Timeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC2,712,446$10M<0.01%-31,25413F-HRTimelineGroup
Sumitomo Mitsui Trust Group, Inc.in group Sumitomo Mitsui Trust Group, …2,412,984$8.9M0.01%-527,80913F-HRTimelineGroup
Amova Asset Management Americas, Inc.in group Amova Asset Management Americ…2,407,018$8.86M0.11%-533,77513F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC2,054,543$7.58M<0.01%+1,718,18513F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC1,997,552$7.37M0.35%+24,27013F-HRTimelineGroup
FMR LLCin group FMR LLC1,761,884$6.5M<0.01%-7,59213F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP1,524,511$5.63M<0.01%-48,30013F-HRTimelineGroup
Redmile Group, LLCin group Redmile Group, LLC1,389,632$5.13M0.34%-201,20013F-HRTimelineGroup
FARALLON CAPITAL MANAGEMENT, L.L.C.1,240,843$4.58M0.03%013F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC1,240,429$4.58M0.04%new13F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/981,335$3.62M<0.01%+404,33113F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co927,538$3.42M<0.01%+10,32613F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP912,597$3.37M<0.01%+25,88113F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO810,095$3.01M<0.01%-34,05913F-HRTimelineGroup
Greenwich Wealth Management LLC768,001$2.83M0.1%+18,00013F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY708,963$2.62M<0.01%+69,50613F-HRTimelineGroup
Alessandra Capital Management, LLC666,603$2.46M1.74%+241,09313F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.648,940$2.39M<0.01%-744,68113F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…648,479$2.39M<0.01%-67,35013F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.533,553$1.97M<0.01%new13F-HRTimelineGroup
MOORE CAPITAL MANAGEMENT, LP500,000$1.84M0.04%013F-HRTimeline
CHELSEA COUNSEL CO449,060$1.66M0.7%-13,28013F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC427,097$1.58M<0.01%new13F-HRTimelineGroup
HighTower Advisors, LLC340,365$1.26M<0.01%+11013F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP304,678$1.12M<0.01%+15613F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…304,444$1.12M<0.01%+26,32413F-HRTimelineGroup
Nuveen, LLCin group TIAA275,931$1.02M<0.01%013F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN251,747$929K<0.01%-67,80313F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp246,344$909K<0.01%-20,87513F-HRTimelineGroup
IQ EQ FUND MANAGEMENT (IRELAND) Ltd225,799$833K0.05%+20,41013F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP216,841$800K<0.01%+74,88413F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd215,708$796K0.01%+58,42613F-HRTimelineGroup
Jain Global LLC215,218$794K0.01%new13F-HRTimeline
JUPITER ASSET MANAGEMENT LTDin group JUPITER ASSET MANAGEMENT LTD209,490$773K<0.01%new13F-HRTimelineGroup
Swiss National Bank208,300$769K<0.01%+29,70013F-HRTimeline
PEAK6 LLCin group PEAK6 LLC208,057$768K0.02%new13F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC195,664$722K<0.01%+148,43213F-HRTimelineGroup
Green Alpha Advisors, LLC185,023$683K0.46%-6,14813F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding170,416$629K+38,538Timeline
Keystone Financial Group166,510$614K0.04%+50013F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/162,325$599K<0.01%+28,57013F-HRTimeline
HRT FINANCIAL LP161,510$595K<0.01%-451,25913F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…157,049$580K<0.01%+70,57613F-HR/ATimeline
Bollard Group LLC151,136$558K0.02%-210,00013F-HRTimeline
Rafferty Asset Management, LLC145,275$536K<0.01%-70,30713F-HRTimeline
ALLIANCEBERNSTEIN L.P.150,300$523K<0.01%+27,84013F-HRTimeline
Invesco Ltd.in group Invesco Ltd.140,308$518K<0.01%+43,43313F-HRTimelineGroup
Concurrent Investment Advisors, LLCin group Concurrent Investment Advisor…131,722$486K<0.01%+57,54513F-HRTimelineGroup
ExodusPoint Capital Management, LP118,464$437K<0.01%new13F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC117,998$435K<0.01%-436,93713F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…117,909$435K0.1%+51,40113F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC117,412$433K<0.01%-623,62713F-HRTimeline
RHUMBLINE ADVISERS116,754$431K<0.01%+2,48513F-HRTimeline
FIL Ltdin group FIL Ltd115,206$425K<0.01%013F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\114,472$422K<0.01%-42,96813F-HRTimelineGroup
Steward Partners Investment Advisory, L…108,290$400K<0.01%-9,16613F-HRTimeline
Palumbo Wealth Management LLC103,801$383K0.08%+1,55513F-HRTimeline
MILESTONE ASSET MANAGEMENT, LLC100,035$369K0.06%new13F-HRTimeline
TD Asset Management Inc94,148$347K<0.01%013F-HRTimeline
LPL Financial LLC92,174$340K<0.01%+25,75013F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…90,735$335K<0.01%-66613F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC88,058$325K<0.01%+24,28513F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC88,029$325K<0.01%-6,03713F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC87,310$322K<0.01%+70,87313F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC82,305$304K<0.01%+29,69013F-HRTimeline
PROFUND ADVISORS LLC72,624$268K0.01%-23,18213F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc66,444$245K<0.01%013F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS66,101$244K<0.01%+31,68813F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC64,800$239K<0.01%-70,00013F-HRTimeline
Jupiter Topco LLCin group Janus Henderson60,900$224K<0.01%13F-HRTimelineGroup
Engineers Gate Manager LP59,133$218K<0.01%-51,21513F-HRTimeline
SG Americas Securities, LLC58,922$217K<0.01%new13F-HRTimeline
&PARTNERS57,460$211K<0.01%-2,01013F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…56,192$207K<0.01%+11,98413F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…50,994$188K<0.01%-13,27913F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC49,941$184K<0.01%+35713F-HRTimelineGroup
Mutual Advisors, LLC45,000$166K<0.01%-20013F-HRTimeline
Quadrature Capital Ltdin group Quadrature Capital Ltd43,663$161K<0.01%-3,23013F-HRTimelineGroup
IvyRock Asset Management (HK) Ltd41,800$154K0.09%013F-HRTimeline
Corient Private Wealth LPin group Corient Private Wealth LP39,078$144K<0.01%-2,14313F-HR/ATimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP40,867$140K<0.01%+56013F-HRTimelineGroup
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…33,569$124K<0.01%+2,72413F-HRTimelineGroup
Crestwood Advisors Group, LLC32,041$118K<0.01%-33313F-HRTimeline
Police & Firemen's Retirement System of…30,751$113K<0.01%013F-HRTimeline
OPPENHEIMER & CO INCin group OPPENHEIMER ASSET MANAGEMENT …29,650$109K<0.01%-4,00613F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC29,184$108K<0.01%+17,14013F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO29,183$108K<0.01%013F-HRTimelineGroup
China Universal Asset Management Co., L…28,745$106K0.01%-3,28813F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM28,646$106K<0.01%+3,85513F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC28,278$104K<0.01%-76213F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …27,353$101K<0.01%-1,51913F-HRTimelineGroup
BLUE BELL PRIVATE WEALTH MANAGEMENT, LLC25,830$95.3K0.01%-1,18513F-HRTimeline
Mariner, LLCin group Mariner, LLC25,389$93.7K<0.01%-53,00913F-HRTimelineGroup
Abacus Planning Group, Inc.25,188$92.9K0.01%013F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC24,363$89.9K<0.01%-6,17513F-HRTimeline
Creative Planningin group Creative Planning21,295$78.6K<0.01%-6,95113F-HRTimelineGroup
Magnetar Financial LLCin group Magnetar Financial LLC21,174$78.1K<0.01%+5,39013F-HRTimelineGroup
E Fund Management Co., Ltd.20,484$75.6K<0.01%-6,61513F-HRTimeline
Schonfeld Strategic Advisors LLC20,189$74.5K<0.01%new13F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC20,138$74.3K<0.01%+2,79313F-HRTimelineGroup
SHELTON WEALTH MANAGEMENT, LLC19,105$70.5K0.03%-96113F-HRTimeline
CIBC WORLD MARKET INC.18,662$68.9K<0.01%new13F-HRTimeline
Graham Capital Management, L.P.18,516$68.3K<0.01%+2,50113F-HRTimeline
KLP KAPITALFORVALTNING AS18,500$68.3K<0.01%013F-HRTimeline
ProShare Advisors LLC18,243$67.3K<0.01%-4,72513F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…18,225$67.2K<0.01%013F-HRTimeline
Cambridge Investment Research Advisors,…16,427$61K<0.01%+4,09013F-HR/ATimeline
IEQ CAPITAL, LLC16,503$60.9K<0.01%-57,51013F-HRTimeline
WEALTH ENHANCEMENT ADVISORY SERVICES, L…15,096$57.1K<0.01%-22,58513F-HRTimeline
LEVIN CAPITAL STRATEGIES, L.P.15,000$55.4K<0.01%013F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC14,755$54.4K<0.01%013F-HRTimelineGroup
THOMPSON DAVIS & CO., INC.14,590$53.8K0.03%-2,65013F-HRTimeline
Sanctuary Advisors, LLC13,400$49.4K<0.01%-49413F-HRTimeline
JTC Employer Solutions Trustee Ltd13,249$49K<0.01%013F-HRTimeline
DRW Securities, LLC13,106$48.4K<0.01%-27,85813F-HRTimeline
Prime Capital Investment Advisors, LLC12,945$47.8K<0.01%013F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…12,910$47.6K<0.01%new13F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD12,681$46.8K<0.01%new13F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…12,107$44.7K<0.01%013F-HRTimelineGroup
Sequoia Financial Advisors, LLC11,686$43.1K<0.01%+1313F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS11,440$42.2K<0.01%+38213F-HRTimeline
Wealthfront Advisers LLC11,301$41.7K<0.01%+92213F-HRTimeline
SYON CAPITAL LLC11,077$40.9K<0.01%new13F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC10,979$40.5K<0.01%+16213F-HRTimeline
BENJAMIN EDWARDS INCin group BENJAMIN EDWARDS INC10,329$38.1K<0.01%-3,52313F-HRTimelineGroup
LANARK FINANCIAL, INC.10,000$36.9K<0.01%+5,00013F-HRTimeline
Kingsview Wealth Management, LLC10,000$36.9K<0.01%-25,00013F-HRTimeline
Forum Financial Management, LPin group Forum Financial Management, LP10,000$36.9K<0.01%013F-HRTimelineGroup
Federation des caisses Desjardins du Qu…9,500$35.1K<0.01%013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.9,398$34.7K<0.01%+5,30113F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND8,434$31.1K<0.01%013F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…8,407$31K<0.01%013F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…6,683$24.7K<0.01%-15,13113F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA5,853$22K<0.01%-3,40113F-HRTimelineGroup
Integrated Wealth Concepts LLC5,162$19K<0.01%new13F-HRTimeline
SIGNATUREFD, LLC5,000$18.4K<0.01%013F-HRTimeline
Glen Eagle Advisors, LLC5,000$18.4K<0.01%-5,00013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC4,544$16.8K<0.01%-4,80213F-HRTimeline
GF FUND MANAGEMENT CO. LTD.3,822$14.1K<0.01%-21413F-HRTimeline
Owl Creek Wealth Partners LLC2,615$9.65K<0.01%013F-HRTimeline
Pacer Advisors, Inc.2,426$9K<0.01%new13F-HRTimeline
Caitong International Asset Management …1,644$6.07K<0.01%+1,26113F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…1,376$5.08K<0.01%-62413F-HRTimelineGroup
Allworth Financial LP1,278$4.72K<0.01%-3,12713F-HRTimeline
NewEdge Advisors, LLC1,000$3.69K<0.01%013F-HRTimeline
Arax Advisory Partners961$3.55K<0.01%+73113F-HRTimeline
GAMMA Investing LLC586$2.16K<0.01%-6113F-HRTimeline
SBI Securities Co., Ltd.580$2.14K<0.01%+18913F-HRTimeline
Quarry LP540$1.99K<0.01%new13F-HRTimeline
Sterling Capital Management LLC536$1.98K<0.01%-2,92613F-HRTimeline
Fairman Group, LLC500$1.84K<0.01%013F-HRTimeline
ROTHSCHILD INVESTMENT LLC384$1.42K<0.01%+213F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…319$1.18K<0.01%013F-HRTimelineGroup
Fortitude Family Office, LLC308$1.14K<0.01%-12813F-HRTimeline
Basecamp Wealth Advisors LLC292$1.08K<0.01%+513F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.260$959<0.01%-63213F-HRTimelineGroup
EASTERN BANK134$494<0.01%new13F-HRTimeline
Sachetta, LLC100$369<0.01%new13F-HRTimeline
HARBOUR INVESTMENTS, INC.78$288<0.01%+413F-HRTimeline
Farther Finance Advisors, LLC55$203<0.01%-9913F-HRTimeline
NATIXISin group Natixis Investment Managers45$166<0.01%new13F-HRTimelineGroup
NFSG Corp45$166<0.01%013F-HRTimeline
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/42$155<0.01%+3213F-HRTimelineGroup
Essential Partners LLC27$100<0.01%-98113F-HRTimeline
IFP Advisors, Inc23$85<0.01%+2113F-HRTimeline
Clearstead Advisors, LLC9$34<0.01%new13F-HRTimeline
Wealth Enhancement Trust Services, Inc.3$11<0.01%new13F-HR/ATimeline
Covestor Ltd105$00%+7413F-HRTimelineValue filed as zero, left out of ratios.