Stonepine Capital Management, LLC
Follow13F filer, CIK 1440771, Bend, OR
Stonepine Capital Management, LLC reported $177,260,827 across 87 holdings for the quarter ended 2026-06-30, in a 13F-HR/A filed 2026-08-17. Its ten largest share positions make up 55.26% of the portfolio.
Filed (acceptance time not in the bulk data set), ingested 13F-HR/A 0001440771-26-000016
- Period
- 2026-06-30
- Reported value
- $177M
- Holdings
- 87
- Top 10 weight
- 55.26%
- New
- 25
- Sold out
- 21
Largest buys vs the previous quarter
| Security | Shares change | Approx. value |
|---|---|---|
| ELOXnew | +397,160 | $5.51M |
| INDVnew | +100,000 | $4.1M |
| EDSAadded | +426,439 | $2.98M |
| MSLEadded | +391,624 | $2.97M |
| CABAadded | +867,100 | $2.7M |
Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.
Largest sells vs the previous quarter
| Security | Shares change | Approx. value |
|---|---|---|
| TENXreduced | -315,200 | -$4.59M |
| ZVRAreduced | -221,299 | -$3.17M |
| XOMAexited | -69,500 | -$2.18M |
| EOLSreduced | -168,929 | -$1.17M |
| ABEOreduced | -189,303 | -$1.17M |
Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.
Holdings, Q2 2026
Share positions as resolved from 13F-HR/A 0001440771-26-000016, largest first. % of portfolio is the value over $131,360,827, the sum of the share positions whose value is usable for ratios (method).
| Security | History | Shares | Value | % of portfolio | Change | Latest event | Timeline |
|---|---|---|---|---|---|---|---|
| VSTMVERASTEM INC | 3,349,627 | $12.8M | 9.74% | +47,327 | Timeline | ||
| EOLSEVOLUS INC | 1,590,162 | $11M | 8.4% | -168,929 | Timeline | ||
| TENXTENAX THERAPEUTICS INC | 660,000 | $9.6M | 7.31% | -315,200 | Timeline | ||
| NKTRNEKTAR THERAPEUTICS | 120,654 | $8.42M | 6.41% | +35,654 | Timeline | ||
| ADMAADMA BIOLOGICS INC | 740,000 | $6.19M | 4.72% | 0 | Timeline | ||
| CAMPCAMP4 THERAPEUTICS CORP | 1,389,622 | $6.07M | 4.62% | 0 | Timeline | ||
| ELOXELOXX PHARMACEUTICALS INC | 397,160 | $5.51M | 4.2% | new | Timeline | ||
| KZIAKAZIA THERAPEUTICS LTD | 345,179 | $4.86M | 3.7% | 0 | Timeline | ||
| INDVINDIVIOR PHARMACEUTICALS INC | 100,000 | $4.1M | 3.12% | new | Timeline | ||
| CRBPCORBUS PHARMACEUTICALS HLDGS | 425,000 | $3.99M | 3.03% | +41,538 | Timeline | ||
| MSLESATELLOS BIOSCIENCE INC | 491,624 | $3.72M | 2.83% | +391,624 | Timeline | ||
| ZVRAZEVRA THERAPEUTICS INC | 258,701 | $3.71M | 2.82% | -221,299 | Timeline | ||
| ABEOABEONA THERAPEUTICS INC | 557,284 | $3.44M | 2.62% | -189,303 | Timeline | ||
| EDSAEDESA BIOTECH INC | 456,439 | $3.19M | 2.43% | +426,439 | Timeline | ||
| CABACABALETTA BIO INC | 917,100 | $2.85M | 2.17% | +867,100 | Timeline | ||
| ANTXAN2 THERAPEUTICS INC | 551,692 | $2.67M | 2.03% | -162,153 | Timeline | ||
| XLOXILIO THERAPEUTICS INC | 225,994 | $2.17M | 1.65% | +161,832 | Timeline | ||
| ACETADICET BIO INC | 245,518 | $2.12M | 1.61% | +23,563 | Timeline | ||
| TELATELA BIO INC | 2,662,427 | $2M | 1.52% | +45,175 | Timeline | ||
| AYTUAYTU BIOPHARMA INC | 912,921 | $1.96M | 1.49% | +120,632 | Timeline | ||
| CRISCURIS INC | 3,312,185 | $1.73M | 1.32% | -414,221 | Timeline | ||
| SPRBSPRUCE BIOSCIENCES INC | 28,795 | $1.55M | 1.18% | new | Timeline | ||
| OKYOOKYO PHARMA LTD | 862,996 | $1.29M | 0.99% | +12,996 | Timeline | ||
| KTTAPASITHEA THERAPEUTICS CORP | 2,201,468 | $1.13M | 0.86% | +1,370,167 | Timeline | ||
| SLGLSOL-GEL TECHNOLOGIES LTD | 14,469 | $1.07M | 0.82% | -13,309 | Timeline | ||
| LUNGPULMONX CORP | 815,436 | $1.06M | 0.81% | +47,148 | Timeline | ||
| XFORX4 PHARMACEUTICALS INC | 224,989 | $1.05M | 0.8% | -110,320 | Timeline | ||
| INABIN8BIO INC | 695,287 | $980K | 0.75% | +31,875 | Timeline | ||
| MLTXMOONLAKE IMMUNOTHERAPEUTICS | 50,000 | $974K | 0.74% | new | Timeline | ||
| QNRXQUOIN PHARMACEUTICALS LTD | 199,486 | $966K | 0.74% | +146,026 | Timeline | ||
| MXCTMAXCYTE INC | 751,606 | $924K | 0.7% | -253,067 | Timeline | ||
| PHATPHATHOM PHARMACEUTICALS INC | 85,010 | $922K | 0.7% | +35,000 | Timeline | ||
| AZTRAZITRA INC | 5,285,476 | $887K | 0.68% | new | Timeline | ||
| CNTBCONNECT BIOPHARMA HLDGS LTD | 364,254 | $867K | 0.66% | +54,254 | Timeline | ||
| HELPCYBIN INC | 129,280 | $855K | 0.65% | -4,780 | Timeline | ||
| RAREULTRAGENYX PHARMACEUTICAL IN | 25,000 | $835K | 0.64% | new | Timeline | ||
| IKTINHIBIKASE THERAPEUTICS INC | 396,179 | $804K | 0.61% | -561,023 | Timeline | ||
| ZNTLZENTALIS PHARMACEUTICALS INC | 161,583 | $784K | 0.6% | -107,517 | Timeline | ||
| CTMXCYTOMX THERAPEUTICS INC. | 205,000 | $769K | 0.59% | +5,000 | Timeline | ||
| NVCTNUVECTIS PHARMA INC | 40,000 | $736K | 0.56% | new | Timeline | ||
| CBIOCRESCENT BIOPHARMA INC. | 40,000 | $720K | 0.55% | -45,000 | Timeline | ||
| PMVPPMV PHARMACEUTICALS INC | 536,086 | $718K | 0.55% | -172,016 | Timeline | ||
| ORKAORUKA THERAPEUTICS INC | 7,500 | $714K | 0.54% | new | Timeline | ||
| RADXRADIOPHARM THERANOSTICS LTD | 51,000,000 | $670K | 0.51% | 0 | Timeline | ||
| OKURONKURE THERAPEUTICS INC | 130,684 | $596K | 0.45% | -1,894 | Timeline | ||
| NGENNERVGEN PHARMA CORP | 271,678 | $560K | 0.43% | new | Timeline | ||
| CALCCALCIMEDICA INC | 622,432 | $545K | 0.41% | new | Timeline | ||
| ARVNARVINAS INC | 60,000 | $499K | 0.38% | +32,500 | Timeline | ||
| BIOABIOAGE LABS INC | 20,000 | $490K | 0.37% | -30,000 | Timeline | ||
| IRDOPUS GENETICS INC | 100,718 | $414K | 0.32% | +32,030 | Timeline | ||
| QTIQT IMAGING HLDGS INC | 100,000 | $407K | 0.31% | new | Timeline | ||
| BOLDBOUNDLESS BIO INC | 154,595 | $386K | 0.29% | -443,087 | Timeline | ||
| SINTSINTX TECHNOLOGIES INC | 209,205 | $333K | 0.25% | new | Timeline | ||
| CLRBCELLECTAR BIOSCIENCES INC | 104,550 | $291K | 0.22% | new | Timeline | ||
| EPRXEUPRAXIA PHARMACEUTICALS INC | 43,491 | $287K | 0.22% | new | Timeline | ||
| SABSSAB BIOTHERAPEUTICS INC | 73,271 | $286K | 0.22% | +23,271 | Timeline | ||
| ANLADLAI NORTYE GROUP LTD | 24,257 | $279K | 0.21% | new | Timeline | ||
| SENSSENSEONICS HLDGS INC | 48,680 | $277K | 0.21% | new | Timeline | ||
| PLRXPLIANT THERAPEUTICS INC | 230,538 | $263K | 0.2% | +5,888 | Timeline | ||
| CDXSCODEXIS INC | 109,662 | $248K | 0.19% | -308,332 | Timeline | ||
| POCIPRECISION OPTICS CORP INC MA | 46,390 | $237K | 0.18% | -53,610 | Timeline | ||
| UPBUPSTREAM BIO INC | 33,432 | $231K | 0.18% | -1,568 | Timeline | ||
| RNTXREIN THERAPEUTICS INC | 218,038 | $227K | 0.17% | new | Timeline | ||
| HRTXHERON THERAPEUTICS INC | 490,787 | $209K | 0.16% | -911,404 | Timeline | ||
| CNSPCNS PHARMACEUTICALS INC | 41,573 | $199K | 0.15% | -19,427 | Timeline | ||
| HUMAHUMACYTE INC | 231,299 | $181K | 0.14% | new | Timeline | ||
| KLRSKALARIS THERAPEUTICS INC | 30,122 | $123K | 0.09% | +9,722 | Timeline | ||
| PCSAPROCESSA PHARMACEUTICALS INC | 55,000 | $106K | 0.08% | 0 | Timeline | ||
| BCABBIOATLA INC | 16,432 | $68K | 0.05% | new | Timeline | ||
| CGENCOMPUGEN LTD | 31,387 | $67.2K | 0.05% | -72,913 | Timeline | ||
| OVIDOVID THERAPEUTICS INC | 21,300 | $57.3K | 0.04% | -18,700 | Timeline | ||
| EVAXEVAXION AS | 17,562 | $54.4K | 0.04% | -2,151 | Timeline |
Options
Puts and calls, as filed. The amount and value describe the underlying shares, not the option premium, so they stay out of % of portfolio (H5).
| Security | Type | Amount | Value | Change |
|---|---|---|---|---|
| ADMAADMA BIOLOGICS INC COM | call | 650,000 | $7.95M | -500,000 |
| INSMINSMED INC Stock | call | 40,000 | $5.6M | new |
| RAREULTRAGENYX PHARMACEUTICAL IN COM | call | 200,000 | $5.5M | new |
| MDTMEDTRONIC PLC COM | call | 50,000 | $4.38M | new |
| ABTABBOTT LABORATORIES COM | call | 40,000 | $3.8M | new |
| BSXBOSTON SCIENTIFIC CORP COM | call | 50,000 | $3.25M | new |
| EOLSEVOLUS INC COM | call | 420,000 | $3.15M | 0 |
| BMRNBIOMARIN PHARMACEUTICAL INC COM | call | 50,000 | $3.12M | new |
| XERSXERIS BIOPHARMA HOLDINGS INC COM | call | 280,000 | $2.1M | 0 |
| HRTXHERON THERAPEUTICS INC COM | call | 1,000,000 | $1.5M | 0 |
| SIBNSI BONE INC COM | call | 100,000 | $1.5M | 0 |
| NMRANEUMORA THERAPEUTICS INC. COM | call | 500,000 | $1.25M | 0 |
| ARDXARDELYX INC COM | call | 150,000 | $1.05M | 0 |
| DCTHDELCATH SYS INC COMMON STOCK | call | 100,000 | $1M | 0 |
| MNKDMANNKIND CORP Stock | call | 250,000 | $750K | -250,000 |
Sold out in Q2 2026
Positions in the previous quarter's report that this quarter's report no longer lists.
| Security | Shares before | Value before | Type |
|---|---|---|---|
| XBISPDR SERIES TRUST | 400,000 | $51.1M | put |
| XBISPDR SERIES TRUST | 400,000 | $51.1M | call |
| TERNTERNS PHARMACEUTICALS INC | 100,000 | $5.27M | call |
| ESTAESTABLISHMENT LABS HLDGS INC | 50,000 | $2.84M | call |
| AREALEXANDRIA REAL ESTATE EQ IN | 50,000 | $2.32M | call |
| ACADACADIA PHARMACEUTICALS INC | 100,000 | $2.23M | call |
| XOMAXOMA ROYALTY CORPORATION | 69,500 | $2.18M | shares |
| SRZNSURROZEN INC | 33,005 | $961K | shares |
| CTMXCYTOMX THERAPEUTICS INC. | 200,000 | $940K | call |
| VRCAVERRICA PHARMACEUTICALS INC | 99,735 | $528K | shares |
| CADLCANDEL THERAPEUTICS INC | 102,500 | $502K | shares |
| ABEOABEONA THERAPEUTICS INC | 100,000 | $448K | call |
| ESTAESTABLISHMENT LABS HLDGS INC | 6,000 | $341K | shares |
| JANXJANUX THERAPEUTICS INC | 20,000 | $278K | shares |
| OABIOMNIAB INC | 164,045 | $258K | shares |
| XERSXERIS BIOPHARMA HOLDINGS INC | 40,030 | $232K | shares |
| NMRANEUMORA THERAPEUTICS INC. | 100,000 | $195K | shares |
| SIBNSI BONE INC | 14,964 | $189K | shares |
| ELDNELEDON PHARMACEUTICALS INC | 35,000 | $108K | shares |
| MNKDMANNKIND CORP | 16,300 | $39.9K | shares |
| BCABBIOATLA INC | 65,387 | $10.5K | shares |
How Q2 2026 was built
Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).
| Filing | Role | Amendment | Filed | Accepted | Ingested |
|---|---|---|---|---|---|
| 13F-HR 0001440771-26-000014 | superseded | 2026-08-14 | acceptance time not in the bulk data set | ||
| 13F-HR/A 0001440771-26-000016 | base | restatement | 2026-08-17 | acceptance time not in the bulk data set |
Filings
Every filing of this filer: 13F reports and notices, the 13D and 13G it filed or is a reporting person of, and Forms 3, 4 and 5 it reported as an owner.
| Filing | Subject | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR/A 0001440771-26-000016 | Quarter ended 2026-06-30 | 2026-08-17 | acceptance time not in the bulk data set | |
| 13F-HR 0001440771-26-000014 | Quarter ended 2026-06-30 | 2026-08-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001440771-26-000002 | Quarter ended 2026-03-31 | 2026-05-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000935836-26-000090 | Quarter ended 2025-12-31 | 2026-02-13 | acceptance time not in the bulk data set | |
| 13F-HR 0000935836-25-000666 | Quarter ended 2025-09-30 | 2025-11-13 | acceptance time not in the bulk data set | |
| 13F-HR 0000935836-25-000497 | Quarter ended 2025-06-30 | 2025-08-13 | acceptance time not in the bulk data set | |
| 13F-HR 0000935836-25-000328 | Quarter ended 2025-03-31 | 2025-05-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000935836-25-000151 | Quarter ended 2024-12-31 | 2025-02-14 | acceptance time not in the bulk data set | |
| 13F-HR 0000935836-24-000663 | Quarter ended 2024-09-30 | 2024-11-13 | acceptance time not in the bulk data set | |
| 13F-HR/A 0000935836-24-000540 | Quarter ended 2024-06-30 | 2024-08-21 | acceptance time not in the bulk data set | |
| 13F-HR 0000935836-24-000513 | Quarter ended 2024-06-30 | 2024-08-13 | acceptance time not in the bulk data set | |
| 13F-HR 0000935836-24-000386 | Quarter ended 2024-03-31 | 2024-05-15 | acceptance time not in the bulk data set | |
| 13F-HR 0000935836-24-000133 | Quarter ended 2023-12-31 | 2024-02-13 | acceptance time not in the bulk data set | |
| 13F-HR 0000935836-23-000688 | Quarter ended 2023-09-30 | 2023-11-13 | acceptance time not in the bulk data set | |
| 13F-HR/A 0000935836-23-000589 | Quarter ended 2023-06-30 | 2023-08-16 | acceptance time not in the bulk data set | |
| 13F-HR 0000935836-23-000564 | Quarter ended 2023-06-30 | 2023-08-11 | acceptance time not in the bulk data set | |
| 13F-HR 0000935836-23-000397 | Quarter ended 2023-03-31 | 2023-05-12 | acceptance time not in the bulk data set | |
| 13F-HR 0000935836-23-000233 | Quarter ended 2022-12-31 | 2023-02-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-22-019570 | Quarter ended 2022-09-30 | 2022-11-10 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-22-015877 | Quarter ended 2022-06-30 | 2022-08-12 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-22-010659 | Quarter ended 2022-03-31 | 2022-05-16 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-22-003693 | Quarter ended 2021-12-31 | 2022-02-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-21-020046 | Quarter ended 2021-09-30 | 2021-11-12 | acceptance time not in the bulk data set | |
| 13F-HR/A 0001567619-21-015565 | Quarter ended 2021-06-30 | 2021-08-16 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-21-015505 | Quarter ended 2021-06-30 | 2021-08-13 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-21-010194 | Quarter ended 2021-03-31 | 2021-05-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-21-003590 | Quarter ended 2020-12-31 | 2021-02-12 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-20-019541 | Quarter ended 2020-09-30 | 2020-11-13 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-20-015104 | Quarter ended 2020-06-30 | 2020-08-13 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-20-010136 | Quarter ended 2020-03-31 | 2020-05-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-20-003323 | Quarter ended 2019-12-31 | 2020-02-13 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-19-021211 | Quarter ended 2019-09-30 | 2019-11-13 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-19-016550 | Quarter ended 2019-06-30 | 2019-08-13 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-19-010831 | Quarter ended 2019-03-31 | 2019-05-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-19-003836 | Quarter ended 2018-12-31 | 2019-02-13 | acceptance time not in the bulk data set | |
| 13F-HR/A 0001567619-18-007015 | Quarter ended 2018-09-30 | 2018-11-28 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-18-005813 | Quarter ended 2018-09-30 | 2018-11-13 | acceptance time not in the bulk data set | |
| 13F-HR 0001567619-18-000669 | Quarter ended 2018-06-30 | 2018-08-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001140361-18-023316 | Quarter ended 2018-03-31 | 2018-05-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001140361-18-007210 | Quarter ended 2017-12-31 | 2018-02-13 | acceptance time not in the bulk data set | |
| 13F-HR 0001140361-17-042192 | Quarter ended 2017-09-30 | 2017-11-13 | acceptance time not in the bulk data set | |
| 13F-HR 0001140361-17-031650 | Quarter ended 2017-06-30 | 2017-08-14 | acceptance time not in the bulk data set | |
| 13F-HR 0001140361-17-020108 | Quarter ended 2017-03-31 | 2017-05-12 | acceptance time not in the bulk data set | |
| 13F-HR 0001140361-17-005766 | Quarter ended 2016-12-31 | 2017-02-10 | acceptance time not in the bulk data set | |
| 13F-HR 0001140361-16-086160 | Quarter ended 2016-09-30 | 2016-11-14 | acceptance time not in the bulk data set | |
| 13F-HR/A 0001140361-16-075782 | Quarter ended 2016-06-30 | 2016-08-11 | acceptance time not in the bulk data set | |
| 13F-HR 0001140361-16-075518 | Quarter ended 2016-06-30 | 2016-08-10 | acceptance time not in the bulk data set | |
| 13F-HR 0001140361-16-064477 | Quarter ended 2016-03-31 | 2016-05-11 | acceptance time not in the bulk data set | |
| 13F-HR 0001140361-16-051710 | Quarter ended 2015-12-31 | 2016-02-11 | acceptance time not in the bulk data set |