13F-HR filed by DAFNA Capital Management LLC
DAFNA Capital Management LLC filed this 13F-HR for the quarter ended 2025-03-31, filed 2025-05-15, with 83 holding rows worth $352,661,806.
- Accession
- 0001389933-25-000002
- Filer
- CIK 1389933
- Filed
- 2025-05-15
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q1 2025
A holdings report, 83 entries on the cover page, a total value of $352,661,806 stated on the cover page (in dollars after the unit check, H1), rows summing to $352,661,806 with VALUE read as dollars as filed, 13F file number 028-12327. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerFischel Nathan028-12328
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| SPDR SER TR | 78464A870 | S&P BIOTECH | 404,505 | $32,805,356 | dollars as filed | |
| STEREOTAXIS INC | 85916J409 | COMMON STOCK | 13,680,554 | $24,077,775 | dollars as filed | |
| REVOLUTION MEDICINES INC COM | 76155X100 | Stock | 656,176 | $23,202,383 | dollars as filed | |
| MERUS N V | N5749R100 | COM | 461,804 | $19,437,330 | dollars as filed | |
| ATRICURE INC | 04963C209 | COM | 592,273 | $19,106,727 | dollars as filed | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 398,100 | $15,999,639 | dollars as filed | |
| BLUEPRINT MEDICINES CORP | 09627Y109 | COM | 152,263 | $13,476,798 | dollars as filed | |
| ISHARES TR | 464287556 | ISHARES BIOTECH | 102,500 | $13,109,750 | dollars as filed | |
| AXOGEN INC | 05463X106 | COM | 680,782 | $12,594,467 | dollars as filed | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 80,398 | $12,530,832 | dollars as filed | |
| IDEAYA BIOSCIENCES INC COM | 45166A102 | Stock | 589,330 | $9,653,225 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 273,739 | $9,183,943 | dollars as filed | |
| KALVISTA PHARMACEUTICALS INC | 483497103 | COM | 752,359 | $8,682,223 | dollars as filed | |
| NEUROCRINE BIOSCIENCES INC | 64125C109 | COM | 71,615 | $7,920,619 | dollars as filed | |
| SYNDAX PHARMACEUTICALS INC | 87164F105 | COM | 544,502 | $6,689,207 | dollars as filed | |
| Day One Biopharmaceuticals Inc | 23954D109 | Common Stock | 731,363 | $5,799,709 | dollars as filed | |
| TANDEM DIABETES CARE INC | 875372203 | COM NEW | 294,208 | $5,637,025 | dollars as filed | |
| UROGEN PHARMA LTD | M96088105 | COMMON STOCK | 492,515 | $5,447,216 | dollars as filed | |
| BIOHAVEN LTD | G1110E107 | COM | 220,235 | $5,294,449 | dollars as filed | |
| MINERALYS THERAPEUTICS INC | 603170101 | COM | 309,200 | $4,910,096 | dollars as filed | |
| ARCUS BIOSCIENCES INC | 03969F109 | COM | 625,126 | $4,907,239 | dollars as filed | |
| Ascendis Pharma A/S | 04351PAD3 | Convertible bond | 4,000,000 | $4,710,000 | dollars as filed | principal |
| DEXCOM INC COM | 252131107 | Stock | 65,552 | $4,476,546 | dollars as filed | |
| BIOCRYST PHARMACEUTICALS INC COM | 09058V103 | Stock | 558,255 | $4,186,913 | dollars as filed | |
| EDGEWISE THERAPEUTICS INC | 28036F105 | COM | 183,140 | $4,029,080 | dollars as filed | |
| LAKEFRONT BIOTHERAPEUTICS NV | 36315X101 | SPON ADR | 130,175 | $3,269,996 | dollars as filed | |
| INOGEN INC | 45780L104 | COM | 458,065 | $3,266,003 | dollars as filed | |
| INSULET CORP COM | 45784P101 | Stock | 11,900 | $3,125,059 | dollars as filed | |
| ALKERMES PLC | G01767105 | SHS | 94,200 | $3,110,484 | dollars as filed | |
| KURA ONCOLOGY INC COM | 50127T109 | Stock | 463,368 | $3,058,229 | dollars as filed | |
| STOKE THERAPEUTICS INC | 86150R107 | COM | 443,998 | $2,952,587 | dollars as filed | |
| IMMUNOVANT INC | 45258J102 | COM | 169,996 | $2,905,232 | dollars as filed | |
| BICARA THERAPEUTICS INC | 055477103 | COM | 212,001 | $2,762,373 | dollars as filed | |
| ACCURAY INC DEL | 004397105 | COM | 1,222,358 | $2,188,021 | dollars as filed | |
| 2SEVENTY BIO INC COMMON STOCK | 901384107 | Stock | 429,252 | $2,120,505 | dollars as filed | |
| PROQR THERAPEUTICS NV | N71542109 | SHS EURO | 1,567,561 | $2,084,856 | dollars as filed | |
| COMPASS PATHWAYS PLC | 20451W101 | SPONSORED ADS | 711,046 | $2,033,592 | dollars as filed | |
| ALLOGENE THERAPEUTICS INC | 019770106 | COM | 1,380,118 | $2,014,972 | dollars as filed | |
| TELA BIO INC | 872381108 | COM | 1,441,029 | $1,758,055 | dollars as filed | |
| ALIGN TECHNOLOGY INC COM | 016255101 | Stock | 11,000 | $1,747,460 | dollars as filed | |
| DENALI THERAPEUTICS INC COM | 24823R105 | Stock | 127,900 | $1,738,801 | dollars as filed | |
| ASTRIA THERAPEUTICS INC COM | 04635X102 | Stock | 314,775 | $1,680,899 | dollars as filed | |
| VIKING THERAPEUTICS INC | 92686J106 | COM | 64,516 | $1,558,061 | dollars as filed | |
| REGULUS THERAPEUTICS INC | 75915K309 | COM | 847,176 | $1,482,558 | dollars as filed | |
| BRAINSWAY LTD | 10501L106 | CMN | 156,533 | $1,482,368 | dollars as filed | |
| ORIC PHARMACEUTICALS INC | 68622P109 | COM | 242,000 | $1,350,360 | dollars as filed | |
| KEROS THERAPEUTICS INC COM | 492327101 | Stock | 130,316 | $1,327,920 | dollars as filed | |
| LEXEO THERAPEUTICS INC | 52886X107 | COMMON STOCK | 378,083 | $1,311,948 | dollars as filed | |
| ITEOS THERAPEUTICS INC | 46565G104 | COM | 213,347 | $1,273,682 | dollars as filed | |
| PALVELLA THERAPEUTICS INC | 697947109 | COMMON STOCK | 43,348 | $1,213,311 | dollars as filed | |
| ARS PHARMACEUTICALS INC | 82835W108 | COM | 95,290 | $1,198,748 | dollars as filed | |
| LINEAGE CELL THERAPEUTICS IN | 53566P109 | COMMON STOCK | 2,511,374 | $1,134,136 | dollars as filed | |
| ALECTOR INC | 014442107 | COMMON STOCK | 912,928 | $1,122,901 | dollars as filed | |
| FOGHORN THERAPEUTICS INC | 344174107 | COMMON STOCK | 304,752 | $1,112,345 | dollars as filed | |
| IMMATICS N.V | N44445109 | SHS | 245,000 | $1,104,950 | dollars as filed | |
| STRUCTURE THERAPEUTICS INC COMP | 86366E106 | EQUITY | 59,000 | $1,021,290 | dollars as filed | |
| VYNE THERAPEUTICS INC | 92941V308 | COM | 636,103 | $1,005,043 | dollars as filed | |
| MEDIWOUND LTD | M68830112 | COMMON STOCK | 64,479 | $1,000,714 | dollars as filed | |
| GOSSAMER BIO INC COM | 38341P102 | Stock | 907,854 | $998,639 | dollars as filed | |
| BIONTECH SE SPONSORED ADS | 09075V102 | ADR | 10,500 | $956,130 | dollars as filed | |
| AUTOLUS THERAPEUTICS PLC SPON | 05280R100 | COM | 586,667 | $909,334 | dollars as filed | |
| SAGE THERAPEUTICS INC | 78667J108 | COM | 108,200 | $860,190 | dollars as filed | |
| KORRO BIO INC | 500946108 | COMMON STOCK | 47,086 | $819,767 | dollars as filed | |
| CENTURY THERAPEUTICS INC | 15673T100 | COM | 1,704,232 | $811,215 | dollars as filed | |
| LARIMAR THERAPEUTICS INC | 517125100 | COM | 371,434 | $798,583 | dollars as filed | |
| POLYPID LTD | M8001Q126 | COM | 291,273 | $789,350 | dollars as filed | |
| TAYSHA GENE THERAPIES INC | 877619106 | COMMON STOCK | 522,500 | $726,275 | dollars as filed | |
| BICYCLE THERAPEUTICS PLC-ADR | 088786108 | SPONSORED ADS | 80,799 | $685,984 | dollars as filed | |
| NEUROGENE INC | 64135M105 | COMMON STOCK | 51,500 | $603,065 | dollars as filed | |
| CARDIFF ONCOLOGY INC | 14147L108 | COM | 150,000 | $471,000 | dollars as filed | |
| ERASCA INC COM | 29479A108 | Stock | 340,000 | $465,800 | dollars as filed | |
| Inflarx Nv | N44821101 | COM | 450,000 | $459,000 | dollars as filed | |
| ADICET BIO INC | 007002108 | COM | 600,000 | $453,000 | dollars as filed | |
| AQUESTIVE THERAPEUTICS INC COM | 03843E104 | Stock | 142,000 | $411,800 | dollars as filed | |
| COMPUGEN LTD | M25722105 | ORD | 272,402 | $397,707 | dollars as filed | |
| ADC THERAPEUTICS SA | H0036K147 | COMMON STOCK | 224,081 | $315,954 | dollars as filed | |
| SUTRO BIOPHARMA INC | 869367102 | COM | 437,079 | $284,364 | dollars as filed | |
| APREA THERAPEUTICS INC | 03836J201 | COM NEW | 137,174 | $279,835 | dollars as filed | |
| BIOMX INC | 09090D301 | COM | 401,136 | $222,911 | dollars as filed | |
| NEVRO CORP | 64157F103 | COM | 38,000 | $221,920 | dollars as filed | |
| BLACK DIAMOND THERAPEUTICS I | 09203E105 | COM | 140,000 | $217,000 | dollars as filed | |
| SPERO THERAPEUTICS INC | 84833T103 | COM | 125,000 | $90,000 | dollars as filed | |
| TENAYA THERAPEUTICS INC | 87990A106 | COM | 47,319 | $26,977 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001389933-25-000002 | this filing | 2025-05-15 | acceptance time not in the bulk data set |