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Opaleye Management Inc.

Reporting owner on Forms 3, 4 and 5, CIK 1595855.

Opaleye Management Inc. reported on 2 issuers in 61 filings, the latest a Form 4 filed 2026-10-05.

Issuers

IssuerRoles in the latest filingFilingsLast filed
Grace Therapeutics, Inc. CIK 144419210% owner32026-10-05
Alpha Cognition Inc. CIK 165592310% owner22026-10-02

Transactions and holdings

Every row of the person's Forms 3, 4 and 5, newest first, with the price and the amount owned after the row as filed.

SecurityDateCodeSharesPriceOwned afterFiling
Grace Therapeutics, Inc. Common Stock, par value $0.0001 per sha…2026-10-05P bought+1,694$2.062,858,657Form 4
Grace Therapeutics, Inc. Common Stock, par value $0.0001 per sha…2026-10-02P bought+20,000$2.06842,856,963Form 4
Alpha Cognition Inc. Common Stock, no par value2026-10-01P bought+19,050$8.69473,222,954Form 4
Alpha Cognition Inc. Common Stock, no par value, holding 100,000Form 4
Grace Therapeutics, Inc. Common Stock, par value $0.0001 per sha…2026-10-01P bought+38,796$2.03532,836,963Form 4
Grace Therapeutics, Inc. Common Stock, par value $0.0001 per sha…2026-09-29P bought+7,849$2.092,798,167Form 4
Alpha Cognition Inc. Common Stock, no par value2026-09-25P bought+13,426$8.473,203,904Form 4
Alpha Cognition Inc. Common Stock, no par value2026-09-24P bought+18,337$8.56643,190,478Form 4
Alpha Cognition Inc. Common Stock, no par value, holding 100,000Form 4
Grace Therapeutics, Inc. Common Stock, par value $0.0001 per sha…2026-09-23P bought+5,318$2.12,790,318Form 4/A
Grace Therapeutics, Inc. Common Stock, par value $0.0001 per sha…2026-09-21P bought+9,771$2.12,785,000Form 4/A

Filings

The person's Forms 3, 4 and 5, and any 13D or 13G naming it.

FilingSubjectFiledAcceptedIngested
Form 4 0001493152-26-045809 Grace Therapeutics, Inc.2026-10-05
Form 4 0001493152-26-045511 Alpha Cognition Inc.2026-10-02
Form 4 0001493152-26-045358 Grace Therapeutics, Inc.2026-10-01
Form 4/A 0001493152-26-045347 Grace Therapeutics, Inc.2026-10-01
Form 4 0001493152-26-044690 Alpha Cognition Inc.2026-09-28
13F-HR 0001420506-26-001803 Quarter ended 2026-06-302026-08-14acceptance time not in the bulk data set
13F-HR 0001420506-26-001151 Quarter ended 2026-03-312026-05-15acceptance time not in the bulk data set
13F-HR/A 0001493152-26-016299 Quarter ended 2025-12-312026-04-13acceptance time not in the bulk data set
13F-HR 0001493152-26-007085 Quarter ended 2025-12-312026-02-17acceptance time not in the bulk data set
13F-HR 0001493152-25-023429 Quarter ended 2025-09-302025-11-14acceptance time not in the bulk data set
13F-HR/A 0001641172-25-024301 Quarter ended 2025-06-302025-08-15acceptance time not in the bulk data set
13F-HR 0001641172-25-023977 Quarter ended 2025-06-302025-08-14acceptance time not in the bulk data set
13F-HR 0001641172-25-010914 Quarter ended 2025-03-312025-05-15acceptance time not in the bulk data set
13F-HR 0001493152-25-006852 Quarter ended 2024-12-312025-02-14acceptance time not in the bulk data set
13F-HR 0001493152-24-045811 Quarter ended 2024-09-302024-11-14acceptance time not in the bulk data set
13F-HR 0001493152-24-032150 Quarter ended 2024-06-302024-08-14acceptance time not in the bulk data set
13F-HR/A 0001493152-24-021780 Quarter ended 2024-03-312024-05-29acceptance time not in the bulk data set
13F-HR 0001493152-24-019869 Quarter ended 2024-03-312024-05-15acceptance time not in the bulk data set
13F-HR 0001493152-24-006653 Quarter ended 2023-12-312024-02-14acceptance time not in the bulk data set
13F-HR 0001493152-23-041364 Quarter ended 2023-09-302023-11-15acceptance time not in the bulk data set
13F-HR 0001493152-23-028636 Quarter ended 2023-06-302023-08-14acceptance time not in the bulk data set
13F-HR 0001493152-23-016769 Quarter ended 2023-03-312023-05-15acceptance time not in the bulk data set
13F-HR 0001493152-23-004277 Quarter ended 2022-12-312023-02-10acceptance time not in the bulk data set
13F-HR 0001493152-22-032068 Quarter ended 2022-09-302022-11-14acceptance time not in the bulk data set
13F-HR 0001493152-22-022856 Quarter ended 2022-06-302022-08-15acceptance time not in the bulk data set
13F-HR 0001493152-22-013764 Quarter ended 2022-03-312022-05-16acceptance time not in the bulk data set
13F-HR 0001493152-22-004434 Quarter ended 2021-12-312022-02-14acceptance time not in the bulk data set
13F-HR 0001493152-21-028799 Quarter ended 2021-09-302021-11-16acceptance time not in the bulk data set
13F-HR 0001493152-21-020260 Quarter ended 2021-06-302021-08-16acceptance time not in the bulk data set
13F-HR 0001493152-21-012017 Quarter ended 2021-03-312021-05-18acceptance time not in the bulk data set
13F-HR 0001493152-21-003697 Quarter ended 2020-12-312021-02-12acceptance time not in the bulk data set
13F-HR 0001493152-20-021694 Quarter ended 2020-09-302020-11-16acceptance time not in the bulk data set
13F-HR 0001493152-20-015902 Quarter ended 2020-06-302020-08-14acceptance time not in the bulk data set
13F-HR 0001493152-20-009140 Quarter ended 2020-03-312020-05-15acceptance time not in the bulk data set
13F-HR 0001493152-20-002529 Quarter ended 2019-12-312020-02-14acceptance time not in the bulk data set
13F-HR 0001493152-19-017503 Quarter ended 2019-09-302019-11-14acceptance time not in the bulk data set
13F-HR 0001493152-19-012567 Quarter ended 2019-06-302019-08-14acceptance time not in the bulk data set
13F-HR 0001493152-19-007425 Quarter ended 2019-03-312019-05-15acceptance time not in the bulk data set
13F-HR 0001493152-19-002114 Quarter ended 2018-12-312019-02-14acceptance time not in the bulk data set
13F-HR 0001493152-18-016123 Quarter ended 2018-09-302018-11-14acceptance time not in the bulk data set
13F-HR 0001493152-18-011830 Quarter ended 2018-06-302018-08-14acceptance time not in the bulk data set
13F-HR 0001493152-18-006822 Quarter ended 2018-03-312018-05-14acceptance time not in the bulk data set
13F-HR 0001493152-18-001743 Quarter ended 2017-12-312018-02-09acceptance time not in the bulk data set
13F-HR 0001493152-17-013210 Quarter ended 2017-09-302017-11-14acceptance time not in the bulk data set
13F-HR 0001493152-17-009239 Quarter ended 2017-06-302017-08-14acceptance time not in the bulk data set
13F-HR 0001493152-17-005196 Quarter ended 2017-03-312017-05-15acceptance time not in the bulk data set
13F-HR 0001144204-17-010166 Quarter ended 2016-12-312017-02-21acceptance time not in the bulk data set
13F-HR 0001546927-16-000542 Quarter ended 2016-09-302016-11-14acceptance time not in the bulk data set
13F-HR 0001546927-16-000512 Quarter ended 2016-06-302016-08-12acceptance time not in the bulk data set
13F-HR/A 0001546927-16-000514 Quarter ended 2016-06-302016-08-12acceptance time not in the bulk data set
13F-HR/A 0001546927-16-000499 Quarter ended 2016-03-312016-05-27acceptance time not in the bulk data set
13F-HR 0001546927-16-000493 Quarter ended 2016-03-312016-05-16acceptance time not in the bulk data set
13F-HR 0001546927-16-000408 Quarter ended 2015-12-312016-02-12acceptance time not in the bulk data set
13F-HR 0001546927-15-000281 Quarter ended 2015-09-302015-11-13acceptance time not in the bulk data set
13F-HR 0001546927-15-000231 Quarter ended 2015-06-302015-08-14acceptance time not in the bulk data set
13F-HR 0001546927-15-000149 Quarter ended 2015-03-312015-05-15acceptance time not in the bulk data set
13F-HR 0001546927-15-000070 Quarter ended 2014-12-312015-02-13acceptance time not in the bulk data set
13F-HR 0001546927-14-000196 Quarter ended 2014-09-302014-11-14acceptance time not in the bulk data set
13F-HR 0001546927-14-000159 Quarter ended 2014-06-302014-08-14acceptance time not in the bulk data set
13F-HR 0001546927-14-000115 Quarter ended 2014-03-312014-05-15acceptance time not in the bulk data set
13F-HR 0001546927-14-000060 Quarter ended 2013-12-312014-02-14acceptance time not in the bulk data set