13F-HR filed by Opaleye Management Inc.
Opaleye Management Inc. filed this 13F-HR for the quarter ended 2021-12-31, filed 2022-02-14, with 39 holding rows worth $471,491,000.
- Accession
- 0001493152-22-004434
- Filer
- CIK 1595855
- Filed
- 2022-02-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2021
A holdings report, 39 entries on the cover page, a total value of $471,491,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $471,486,000 with VALUE read as thousands by filing date, 13F file number 028-15896. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| CODEXIS INC | 192005106 | COM | 1,345,000 | $42,058,000 | thousands by filing date | |
| OCULAR THERAPEUTIX INC | 67576A100 | COM | 5,974,800 | $41,644,000 | thousands by filing date | |
| CHIMERIX INC COM | 16934W106 | Stock | 5,580,000 | $35,879,000 | thousands by filing date | |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 844,000 | $32,612,000 | thousands by filing date | |
| HARROW INC | 415858109 | COM | 3,285,000 | $28,382,000 | thousands by filing date | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 580,000 | $26,436,000 | thousands by filing date | |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 724,400 | $20,580,000 | thousands by filing date | |
| PROTARA THERAPEUTICS INC | 74365U107 | COM STK | 2,650,000 | $17,996,000 | thousands by filing date | |
| SEMLER SCIENTIFIC INC | 81684M104 | COM | 172,000 | $15,764,000 | thousands by filing date | |
| STEREOTAXIS INC | 85916J409 | COMMON STOCK | 2,526,500 | $15,664,000 | thousands by filing date | |
| KEROS THERAPEUTICS INC COM | 492327101 | Stock | 265,750 | $15,549,000 | thousands by filing date | |
| KINIKSA PHARMACEUTICALS LTD | G5269C101 | COM CL A | 1,025,000 | $12,064,000 | thousands by filing date | |
| PROTAGONIST THERAPEUTICS | 74366E102 | COM | 342,000 | $11,696,000 | thousands by filing date | |
| PROQR THERAPEUTICS NV | N71542109 | SHS EURO | 1,435,510 | $11,498,000 | thousands by filing date | |
| ETON PHARMACEUTICALS INC | 29772L108 | COMMON STOCK | 2,385,000 | $10,232,000 | thousands by filing date | |
| SUTRO BIOPHARMA INC | 869367102 | COM | 680,000 | $10,118,000 | thousands by filing date | |
| MERUS N V | N5749R100 | COM | 317,800 | $10,106,000 | thousands by filing date | |
| LARIMAR THERAPEUTICS INC | 517125100 | COM | 883,602 | $9,534,000 | thousands by filing date | |
| FORTRESS BIOTECH INC | 34960Q109 | COM | 3,750,000 | $9,375,000 | thousands by filing date | |
| REATA PHARMACEUTICALS INC | 75615P103 | CL A | 330,000 | $8,702,000 | thousands by filing date | |
| TRACON PHARMACEUTICALS INC | 89237H209 | COM NEW | 3,055,000 | $8,462,000 | thousands by filing date | |
| GINKGO BIOWORKS HOLDINGS INC | 37611X100 | CL A SHS | 929,780 | $7,726,000 | thousands by filing date | |
| VAXCYTE INC COM | 92243G108 | Stock | 315,800 | $7,513,000 | thousands by filing date | |
| MACROGENICS INC | 556099109 | COM | 462,000 | $7,415,000 | thousands by filing date | |
| XOMA ROYALTY CORPORATION | 98419J206 | COMMON STOCK | 338,350 | $7,055,000 | thousands by filing date | |
| TELA BIO INC | 872381108 | COM | 449,867 | $5,758,000 | thousands by filing date | |
| HYPERFINE INC | 44916K106 | Common Stock | 763,075 | $5,523,000 | thousands by filing date | |
| BRIDGEBIO PHARMA INC | 10806X102 | COM | 328,100 | $5,473,000 | thousands by filing date | |
| NEOLEUKIN THERAPEUTICS INC | 64049K104 | COM | 1,047,300 | $5,048,000 | thousands by filing date | |
| 4D MOLECULAR THERAPEUTICS INC COM | 35104E100 | Stock | 229,000 | $5,024,000 | thousands by filing date | |
| VERASTEM INC | 92337C104 | COM | 2,325,000 | $4,766,000 | thousands by filing date | |
| SIERRA ONCOLOGY INC | 82640U404 | CMN | 165,778 | $3,604,000 | thousands by filing date | |
| MEI PHARMA INC | 55279B202 | COM NEW | 1,315,000 | $3,511,000 | thousands by filing date | |
| NUCANA PLC | 67022C106 | ADR | 1,189,000 | $2,830,000 | thousands by filing date | |
| AVALO THERAPEUTICS INC | 05338F108 | CMN | 1,459,400 | $2,481,000 | thousands by filing date | |
| SYNLOGIC INC | 87166L100 | COM | 850,000 | $2,057,000 | thousands by filing date | |
| AVEO PHARMACEUTICALS INC | 053588307 | COM | 263,400 | $1,235,000 | thousands by filing date | |
| LIQUIDIA CORPORATION COM NEW | 53635D202 | Stock | 16,800 | $82,000 | thousands by filing date | |
| NULL | 09071M205 | NULL | 16,667 | $34,000 | thousands by filing date |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001493152-22-004434 | this filing | 2022-02-14 | acceptance time not in the bulk data set |