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13F-HR/A filed by Opaleye Management Inc.

Opaleye Management Inc. filed this 13F-HR/A for the quarter ended 2016-06-30, filed 2016-08-12, with 49 holding rows worth $149,709,000.

Accession
0001546927-16-000514
Filed
2016-08-12
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q2 2016

A holdings report, amendment of type restatement, 49 entries on the cover page, a total value of $149,709,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $149,709,000 with VALUE read as thousands by filing date, 13F file number 028-15896. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
AXOGEN INC05463X106COM2,120,000$14,586,000thousands by filing date
Medgenics Inc New58436Q203COM NEW1,950,000$10,823,000thousands by filing date
ARIAD PHARMACEUTICALS INC04033A100COM1,250,000$9,238,000thousands by filing date
FIBROGEN INC31572Q808COM330,000$5,415,000thousands by filing date
PROTALIX BIOTHERAPEUTICS INC74365AAB7NOTE 4.500% 9/18,200,000$5,248,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM250,000$5,063,000thousands by filing date
ITEK 5 02/15/2045780VAA0Bond 30/360P2 U645,000$4,799,000thousands by filing date
IMPRIMIS PHARMA IMMY45323A201COMMON1,267,500$4,766,000thousands by filing date
CODEXIS INC192005106COM1,178,500$4,749,000thousands by filing date
ADAMAS PHARMACEUTICALS INC00548A106COM300,000$4,542,000thousands by filing date
FOAMIX PHARMACEUTICALS LTDM46135105SHS695,000$4,413,000thousands by filing date
CARA THERAPEUTICS INC140755109COM835,000$4,016,000thousands by filing date
AMARIN CORP PLC023111206SPONS ADR NEW1,760,000$3,802,000thousands by filing date
AGIOS PHARMACEUTICALS INC00847X104COM85,000$3,561,000thousands by filing date
HORIZON PHARMA PLCG4617B105SHS200,000$3,294,000thousands by filing date
ULTRAGENYX PHARMACEUTICAL IN90400D108COM65,000$3,179,000thousands by filing date
MACROGENICS INC556099109COM112,000$3,023,000thousands by filing date
IMMUNOMEDICS INC452907108COM1,300,000$3,016,000thousands by filing date
INTEC PHARMA LTD JERUSALEMM53644106SHS650,000$2,989,000thousands by filing date
AMAG PHARMACEUTICALS INC00163U106COM120,000$2,870,000thousands by filing date
CHIMERIX INC COM16934W106Stock675,000$2,653,000thousands by filing date
SUPERNUS PHARMACEUTICALS868459108COM125,000$2,546,000thousands by filing date
GLOBAL BLOOD THERAPEUTICS USD37890U108COM152,000$2,522,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock410,000$2,419,000thousands by filing date
EDGE THERAPEUTICS INC279870109COM225,600$2,281,000thousands by filing date
Lion Biotechnologies53619R102COM260,000$2,106,000thousands by filing date
CYNAPSUS THERAPEUTICS INC23257Y859COM PAR NO PAR125,000$2,094,000thousands by filing date
PARATEK PHARMACEUTICALS INC699374302Equity146,700$2,041,000thousands by filing date
NABRIVA THERAPEUTICS AG62957M104SPONSORED ADR270,000$2,025,000thousands by filing date
AQUINOX PHARMACEUTICALS INC03842B101COM295,000$1,953,000thousands by filing date
EAGLE PHARMACEUTICALS INC269796108COM50,000$1,940,000thousands by filing date
ZOGENIX INC98978L105COM240,000$1,932,000thousands by filing date
TRILLIUM THERAPEUTICS INC COM NEW89620X506Stock195,000$1,751,000thousands by filing date
SERES THERAPEUTICS INC81750R102COM57,500$1,670,000thousands by filing date
CYTOMX THERAPEUTICS INC23284F105COMMON STOCK160,000$1,634,000thousands by filing date
TONIX PHARMACEUTICALS HOLDING890260201COM NEW800,000$1,592,000thousands by filing date
AFFIMED N VN01045108COM595,000$1,476,000thousands by filing date
INNOCOLL HLDGS PLCG4783X105SHS265,000$1,460,000thousands by filing date
AURIS MED HLDG AGH03579101COM340,000$1,425,000thousands by filing date
OCULAR THERAPEUTIX INC67576A100COM260,000$1,287,000thousands by filing date
PROTEOSTASIS THERAPEUTICS IN74373B109COM105,000$1,274,000thousands by filing date
CORIUM INTL INC21887L107COM360,000$1,249,000thousands by filing date
TENAX THERAPEUTICS INC88032L100COM465,000$1,190,000thousands by filing date
TG THERAPEUTICS INC COM88322Q108Stock175,000$1,061,000thousands by filing date
EVOKE PHARMA INC30049G104COM130,000$891,000thousands by filing date
NEURODERM LTDM74231107ORD SHS52,500$853,000thousands by filing date
CIDARA THERAPEUTICS INC COM NEW171757107Stock43,000$443,000thousands by filing date
ADAPTIMMUNE THERAPEUTICS PLC00653A107SPONDS ADR40,000$326,000thousands by filing date
BIOLINERX LTD-SPONS ADR09071M106SPON250,000$223,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001546927-16-000512 superseded2016-08-12acceptance time not in the bulk data set
13F-HR/A 0001546927-16-000514this filing2016-08-12acceptance time not in the bulk data set