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13F-HR filed by Opaleye Management Inc.

Opaleye Management Inc. filed this 13F-HR for the quarter ended 2021-03-31, filed 2021-05-18, with 58 holding rows worth $680,802,000.

Accession
0001493152-21-012017
Filed
2021-05-18
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2021

A holdings report, 58 entries on the cover page, a total value of $680,802,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $680,804,000 with VALUE read as thousands by filing date, 13F file number 028-15896. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
OCULAR THERAPEUTIX INC67576A100COM6,480,000$106,337,000thousands by filing date
CHIMERIX INC COM16934W106Stock4,490,000$43,284,000thousands by filing date
PROTARA THERAPEUTICS INC74365U107COM STK2,558,472$40,270,000thousands by filing date
BRIDGEBIO PHARMA INC10806X102COM583,767$35,960,000thousands by filing date
CODEXIS INC192005106COM1,400,000$32,046,000thousands by filing date
ETON PHARMACEUTICALS INC29772L108COMMON STOCK4,040,000$29,573,000thousands by filing date
MACROGENICS INC556099109COM666,200$21,218,000thousands by filing date
TRACON PHARMACEUTICALS INC89237H209COM NEW2,518,371$20,726,000thousands by filing date
HARROW INC415858109COM3,065,416$20,692,000thousands by filing date
CELLDEX THERAPEUTICS INC NEW15117B202COM NEW985,000$20,291,000thousands by filing date
XOMA ROYALTY CORPORATION98419J206COMMON STOCK437,500$17,854,000thousands by filing date
STEREOTAXIS INC85916J409COMMON STOCK2,526,500$16,978,000thousands by filing date
NEOLEUKIN THERAPEUTICS INC64049K104COM1,225,000$15,080,000thousands by filing date
FORTRESS BIOTECH INC34960Q109COM3,875,000$13,679,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW580,000$13,491,000thousands by filing date
AUTOLUS THERAPEUTICS PLC SPON05280R100COM2,112,918$12,107,000thousands by filing date
GEMINI THERAPEUTICS INC36870G105CMN810,500$10,982,000thousands by filing date
DECIPHERA PHARMACEUTICALS IN24344T101COM222,000$9,954,000thousands by filing date
SERES THERAPEUTICS INC81750R102COM300,000$9,804,000thousands by filing date
KEROS THERAPEUTICS INC COM492327101Stock157,500$9,694,000thousands by filing date
Checkpoint Therapeutics Inc Com162828107COM2,925,963$9,188,000thousands by filing date
PROQR THERAPEUTICS NVN71542109SHS EURO1,303,000$8,613,000thousands by filing date
ESSA PHARMA INC29668H708COM NEW284,050$8,252,000thousands by filing date
ACUTUS MED INC005111109COM614,990$8,222,000thousands by filing date
ADAMAS PHARMACEUTICALS INC00548A106COM1,670,600$8,019,000thousands by filing date
CERECOR INC15671L109COM2,600,000$7,852,000thousands by filing date
SUTRO BIOPHARMA INC869367102COM341,950$7,783,000thousands by filing date
PROTAGONIST THERAPEUTICS74366E102COM297,000$7,692,000thousands by filing date
IMMUNOVANT INC45258J102COM467,000$7,491,000thousands by filing date
VAXCYTE INC COM92243G108Stock357,800$7,067,000thousands by filing date
SANARA MEDTECH INC79957L100COMMON STOCK225,000$7,009,000thousands by filing date
CATALYST BIOSCIENCES INC14888D208COM1,250,000$6,300,000thousands by filing date
AVEO PHARMACEUTICALS INC053588307COM835,000$6,112,000thousands by filing date
KINIKSA PHARMACEUTICALS LTDG5269C101COM CL A320,926$5,940,000thousands by filing date
VERASTEM INC92337C104COM2,325,000$5,743,000thousands by filing date
TELA BIO INC872381108COM365,000$5,439,000thousands by filing date
MEI PHARMA INC55279B202COM NEW1,556,000$5,337,000thousands by filing date
CARDIFF ONCOLOGY INC14147L108COM576,000$5,334,000thousands by filing date
SIO GENE THERAPIES INC829399104COM2,000,000$5,220,000thousands by filing date
APTOSE BIOSCIENCES INC COM03835T200Stock871,800$5,209,000thousands by filing date
MYOVANT SCIENCES LTDG637AM102COMMON STOCK-FO249,800$5,141,000thousands by filing date
FIBROGEN INC31572Q808COM147,000$5,102,000thousands by filing date
LUMOS PHARMA INC55028X109COM376,900$4,410,000thousands by filing date
KEZAR LIFE SCIENCES INC49372L100COM711,200$4,239,000thousands by filing date
OPTINOSE INC68404V100COM826,000$3,048,000thousands by filing date
HIGHCAPE CAP ACQUISITION COR42984L105COM CL A241,300$2,876,000thousands by filing date
CRINETICS PHARMACEUTICALS INC COM22663K107Stock188,000$2,873,000thousands by filing date
EDAP TMS S A268311107SPONSORED ADR341,300$2,867,000thousands by filing date
SIERRA ONCOLOGY INC82640U404CMN151,139$2,604,000thousands by filing date
BIOHAVEN PHARMACEUTICAL HOLDING11196105COM25,000$1,709,000thousands by filing date
ALPINE IMMUNE SCIENCES INC02083G100COM156,500$1,659,000thousands by filing date
AERPIO PHARMACEUTICALS INC00810B105COM1,000,000$1,290,000thousands by filing date
AYALA PHARMACEUTICALS INC05465V108COM108,551$1,184,000thousands by filing date
CONTRAFECT CORP212326300COM244,000$1,171,000thousands by filing date
DIANTHUS THERAPEUTICS INC COM55910K108Stock88,400$1,047,000thousands by filing date
VIRACTA THERAPEUTICS INC92765F108COM103,600$958,000thousands by filing date
LEAP THERAPEUTICS INC52187K101COM388,100$737,000thousands by filing date
NULL09071M205NULL16,667$47,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001493152-21-012017this filing2021-05-18acceptance time not in the bulk data set