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13F-HR filed by Opaleye Management Inc.

Opaleye Management Inc. filed this 13F-HR for the quarter ended 2021-06-30, filed 2021-08-16, with 48 holding rows worth $602,061,000.

Accession
0001493152-21-020260
Filed
2021-08-16
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q2 2021

A holdings report, 48 entries on the cover page, a total value of $602,061,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $602,060,000 with VALUE read as thousands by filing date, 13F file number 028-15896. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
OCULAR THERAPEUTIX INC67576A100COM6,480,000$91,886,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
CHIMERIX INC COM16934W106Stock4,630,000$37,040,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
CELLDEX THERAPEUTICS INC NEW15117B202COM NEW985,000$32,938,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
BRIDGEBIO PHARMA INC10806X102COM517,150$31,525,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
CODEXIS INC192005106COM1,345,000$30,478,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
ETON PHARMACEUTICALS INC29772L108COMMON STOCK3,692,600$29,310,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
HARROW INC415858109COM3,140,000$29,171,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
PROTARA THERAPEUTICS INC74365U107COM STK2,558,472$24,920,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
STEREOTAXIS INC85916J409COMMON STOCK2,526,500$24,355,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
TRACON PHARMACEUTICALS INC89237H209COM NEW2,518,371$16,344,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
KINIKSA PHARMACEUTICALS LTDG5269C101COM CL A1,155,200$16,092,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
MACROGENICS INC556099109COM578,150$15,529,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
PROTAGONIST THERAPEUTICS74366E102COM330,222$14,820,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
FORTRESS BIOTECH INC34960Q109COM3,875,000$13,834,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
XOMA ROYALTY CORPORATION98419J206COMMON STOCK343,600$11,682,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
CYTOKINETICS INC23282W605COM NEW580,000$11,478,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
NEOLEUKIN THERAPEUTICS INC64049K104COM1,156,200$10,672,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
ACUTUS MED INC005111109COM599,990$10,188,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
KEROS THERAPEUTICS INC COM492327101Stock235,000$9,980,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
VERASTEM INC92337C104COM2,325,000$9,463,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
PROQR THERAPEUTICS NVN71542109SHS EURO1,380,400$9,304,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
SUTRO BIOPHARMA INC869367102COM496,900$9,237,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
ADAMAS PHARMACEUTICALS INC00548A106COM1,670,600$8,821,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
ESSA PHARMA INC29668H708COM NEW284,050$8,115,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
VAXCYTE INC COM92243G108Stock357,800$8,054,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
DECIPHERA PHARMACEUTICALS IN24344T101COM205,381$7,519,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
LARIMAR THERAPEUTICS INC517125100COM727,800$7,147,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
TELA BIO INC872381108COM440,465$7,096,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
SERES THERAPEUTICS INC81750R102COM250,000$5,963,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
SIO GENE THERAPIES INC829399104COM2,000,000$5,258,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
CM LIFE SCIENCES INC18978W109COM CL A373,828$5,237,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
CERECOR INC15671L109COM1,567,494$5,126,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
MEI PHARMA INC55279B202COM NEW1,565,000$4,460,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
AVEO PHARMACEUTICALS INC053588307COM647,000$4,264,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
FORMA THERAPEUTICS HLDGS INC34633R104SHS171,000$4,256,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
LUMOS PHARMA INC55028X109COM382,000$3,820,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
OPTINOSE INC68404V100COM1,226,600$3,815,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
KEZAR LIFE SCIENCES INC49372L100COM697,800$3,789,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
CRINETICS PHARMACEUTICALS INC COM22663K107Stock200,500$3,779,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
APTOSE BIOSCIENCES INC COM03835T200Stock980,000$3,254,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
SIERRA ONCOLOGY INC82640U404CMN165,500$3,222,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
CARDIFF ONCOLOGY INC14147L108COM463,000$3,079,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
VIRACTA THERAPEUTICS INC92765F108COM257,189$2,917,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
PHARVARIS NVN69605108COMMON STOCK79,837$1,487,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
LEAP THERAPEUTICS INC52187K101COM540,000$886,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
CONTRAFECT CORP212326300COM57,900$255,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
CIDARA THERAPEUTICS INC COM NEW171757107Stock73,351$148,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.
NULL09071M205NULL16,667$47,000thousands by filing dateThe filing omitted confidential holdings, a later amendment may add them.

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001493152-21-020260this filing2021-08-16acceptance time not in the bulk data set