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13F-HR filed by Opaleye Management Inc.

Opaleye Management Inc. filed this 13F-HR for the quarter ended 2018-12-31, filed 2019-02-14, with 47 holding rows worth $267,975,000.

Accession
0001493152-19-002114
Filed
2019-02-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2018

A holdings report, 47 entries on the cover page, a total value of $267,975,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $267,975,000 with VALUE read as thousands by filing date, 13F file number 028-15896. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
CODEXIS INC192005106COM1,750,000$29,225,000thousands by filing date
AXOGEN INC05463X106COM1,300,000$26,559,000thousands by filing date
LOXO ONCOLOGY INC548862101COM175,000$24,512,000thousands by filing date
AMARIN CORP PLC023111206SPONS ADR NEW1,250,000$17,012,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM300,000$16,173,000thousands by filing date
IMPRIMIS PHARMA IMMY45323A201COMMON1,722,000$9,798,000thousands by filing date
FIBROGEN INC31572Q808COM200,000$9,256,000thousands by filing date
DECIPHERA PHARMACEUTICALS IN24344T101COM340,000$7,136,000thousands by filing date
EPIZYME INC29428V104COM1,125,000$6,930,000thousands by filing date
PTC THERAPEUTICS INC69366J200COM190,000$6,520,000thousands by filing date
XENCOR INC98401F105COMMON STOCK180,000$6,508,000thousands by filing date
VIKING THERAPEUTICS INC92686J106COM825,000$6,311,000thousands by filing date
STRONGBRIDGE BIOPHARMA PLCG85347105SHS USD1,390,000$6,227,000thousands by filing date
CERECOR INC15671L109COM2,185,536$6,212,000thousands by filing date
FENNEC PHARMACEUTICALS INC31447P100COMMON STOCK900,000$5,742,000thousands by filing date
SANGAMO THERAPEUTICS INC800677106COM500,000$5,740,000thousands by filing date
CYMABAY THERAPEUTICS INC23257D103COM725,000$5,705,000thousands by filing date
POLARITYTE INC731094108COM400,000$5,396,000thousands by filing date
AUDENTES THERAPEUTICS INC.05070R104Common Stock250,000$5,330,000thousands by filing date
CHIMERIX INC COM16934W106Stock2,020,000$5,191,000thousands by filing date
XOMA ROYALTY CORPORATION98419J206COMMON STOCK400,000$5,060,000thousands by filing date
IMMUNOGEN INC45253H101COMMON STOCK1,021,000$4,900,000thousands by filing date
APELLIS PHARMACEUTICALS INC03753U106COM275,000$3,627,000thousands by filing date
AIMMUNE THERAPEUTICS INC.00900T107Common Stock150,000$3,588,000thousands by filing date
ABEONA THERAPEUTICS INC00289Y107COM450,000$3,213,000thousands by filing date
ETON PHARMACEUTICALS INC29772L108COMMON STOCK523,000$3,200,000thousands by filing date
ACADIA PHARMACEUTICALS INC004225108COM195,000$3,153,000thousands by filing date
TRICIDA INC89610F101COM123,000$2,900,000thousands by filing date
DIANTHUS THERAPEUTICS INC COM55910K108Stock505,000$2,878,000thousands by filing date
CIDARA THERAPEUTICS INC COM NEW171757107Stock1,200,000$2,820,000thousands by filing date
AVENUE THERAPEUTICS INC05360L205COM496,000$2,678,000thousands by filing date
TG THERAPEUTICS INC COM88322Q108Stock550,000$2,255,000thousands by filing date
PUMA BIOTECHNOLOGY INC74587V107COMMON STOCK100,000$2,035,000thousands by filing date
EIDOS THERAPEUTICS INC.28249H104Common Stock140,000$1,926,000thousands by filing date
MACROGENICS INC556099109COM150,000$1,905,000thousands by filing date
CLEMENTIA PHARMACEUTICALS IN185575107COM150,000$1,764,000thousands by filing date
ZYMEWORKS INC98985W102COM105,000$1,541,000thousands by filing date
COLLEGIUM PHARMACEUTICAL INC19459J104COM80,000$1,373,000thousands by filing date
MIRAGEN THERAPEUTICS INC60463E103COM385,000$1,166,000thousands by filing date
CTI BIOPHARMA CORP12648L601COM1,400,000$1,027,000thousands by filing date
PROTALIX BIOTHERAPEUTICS INC74365A101COM2,500,000$777,000thousands by filing date
ODONATE THERAPEUTICS INC676079106COM49,000$690,000thousands by filing date
AXOVANT SCIENCES LTDG0750W104COM580,000$577,000thousands by filing date
DERMIRA INC24983L104COM75,000$539,000thousands by filing date
ASSERTIO THERAPEUTICS INC04545L107COM120,000$433,000thousands by filing date
ARQULE INC04269E107COM200,000$358,000thousands by filing date
BIOLINERX LTD-SPONS ADR09071M106SPON250,000$109,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001493152-19-002114this filing2019-02-14acceptance time not in the bulk data set