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13F-HR filed by Opaleye Management Inc.

Opaleye Management Inc. filed this 13F-HR for the quarter ended 2015-12-31, filed 2016-02-12, with 53 holding rows worth $239,178,000.

Accession
0001546927-16-000408
Filed
2016-02-12
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2015

A holdings report, 53 entries on the cover page, a total value of $239,178,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $239,178,000 with VALUE read as thousands by filing date, 13F file number 028-15896. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
ULTRAGENYX PHARMACEUTICAL IN90400D108COM110,000$12,340,000thousands by filing date
AXOGEN INC05463X106COM2,120,000$10,600,000thousands by filing date
FIBROGEN INC31572Q808COM325,000$9,903,000thousands by filing date
GERON CORP374163103COM1,825,000$8,833,000thousands by filing date
Medgenics Inc New58436Q203COM NEW1,390,000$8,368,000thousands by filing date
IMPRIMIS PHARMA IMMY45323A201COMMON1,205,000$8,351,000thousands by filing date
PROTALIX BIOTHERAPEUTICS INC74365AAB7NOTE 4.500% 9/18,100,000$8,262,000thousands by filing date
OPHTHOTECH CORP683745103COM105,000$8,246,000thousands by filing date
ARIAD PHARMACEUTICALS INC04033A100COM1,310,000$8,188,000thousands by filing date
EAGLE PHARMACEUTICALS INC269796108COM85,000$7,537,000thousands by filing date
ITEK 5 02/15/2045780VAA0Bond 30/360P2 U645,000$7,308,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM275,000$7,244,000thousands by filing date
CARA THERAPEUTICS INC140755109COM427,000$7,199,000thousands by filing date
CODEXIS INC192005106COM1,600,000$6,768,000thousands by filing date
RETROPHIN INC761299106COM345,000$6,655,000thousands by filing date
RELYPSA INC759531106Common Stock220,000$6,235,000thousands by filing date
CEMPRA INC15130J109COM200,000$6,226,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM100,000$5,830,000thousands by filing date
SUPERNUS PHARMACEUTICALS868459108COM420,000$5,645,000thousands by filing date
DEPOMED INC249908104COM300,000$5,439,000thousands by filing date
ADAMAS PHARMACEUTICALS INC00548A106COM190,000$5,380,000thousands by filing date
AMAG PHARMACEUTICALS INC00163U106COM150,000$4,529,000thousands by filing date
TONIX PHARMACEUTICALS HOLDING890260201COM NEW565,000$4,334,000thousands by filing date
AVINGER INC053734109COM190,000$4,315,000thousands by filing date
AFFIMED N VN01045108COM595,000$4,236,000thousands by filing date
FOAMIX PHARMACEUTICALS LTDM46135105SHS500,000$4,055,000thousands by filing date
EAGLE PHARMACEUTICALS INC838828509COM1,440,000$3,816,000thousands by filing date
LA JOLLA PHARMACEUTICAL CO503459904CALL140,000$3,780,000thousands by filing date
TG THERAPEUTICS INC COM88322Q108Stock300,000$3,579,000thousands by filing date
INTEC PHARMA LTD JERUSALEMM53644106SHS630,000$3,377,000thousands by filing date
AMARIN CORP PLC023111206SPONS ADR NEW1,760,000$3,326,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM55,000$3,111,000thousands by filing date
FLAMEL TECHNOLOGIES-SP ADR338488109SPON250,000$3,053,000thousands by filing date
AGILE THERAPEUTICS INC00847L100COM300,000$2,928,000thousands by filing date
CORIUM INTL INC21887L107COM355,000$2,883,000thousands by filing date
TRILLIUM THERAPEUTICS INC COM NEW89620X506Stock210,000$2,648,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock300,000$2,412,000thousands by filing date
XOMA CORP DEL98419J107COM1,700,000$2,261,000thousands by filing date
ZOGENIX INC98978L105COM150,000$2,211,000thousands by filing date
ALDER BIOPHARMACEUTICALS INC014339105COM65,000$2,147,000thousands by filing date
NABRIVA THERAPEUTICS AG62957M104SPONSORED ADR220,000$2,116,000thousands by filing date
AURIS MED HLDG AGH03579101COM375,000$1,834,000thousands by filing date
TENAX THERAPEUTICS INC88032L100COM540,000$1,771,000thousands by filing date
CYNAPSUS THERAPEUTICS INC23257Y859COM PAR NO PAR110,000$1,682,000thousands by filing date
Accelerate Diagnostics00430H102COM75,000$1,612,000thousands by filing date
CELLECTIS ADS15117K103COM50,000$1,552,000thousands by filing date
MACROGENICS INC556099109COM35,000$1,084,000thousands by filing date
VITAE PHARMACEUTICALS INC92847N103COM58,500$1,059,000thousands by filing date
IMMUNOMEDICS INC452907108COM290,000$890,000thousands by filing date
ACHAOGEN INCOO4449104COM125,000$718,000thousands by filing date
SANGAMO THERAPEUTICS INC800677106COM60,000$548,000thousands by filing date
EVOKE PHARMA INC30049G104COM130,000$429,000thousands by filing date
BIOLINERX LTD-SPONS ADR09071M106SPON250,000$325,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001546927-16-000408this filing2016-02-12acceptance time not in the bulk data set