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13F-HR filed by Opaleye Management Inc.

Opaleye Management Inc. filed this 13F-HR for the quarter ended 2016-09-30, filed 2016-11-14, with 44 holding rows worth $191,082,000.

Accession
0001546927-16-000542
Filed
2016-11-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q3 2016

A holdings report, 44 entries on the cover page, a total value of $191,082,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $191,082,000 with VALUE read as thousands by filing date, 13F file number 028-15896. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
BLUEPRINT MEDICINES CORP09627Y109COM785,000$23,315,000thousands by filing date
AXOGEN INC05463X106COM2,000,000$18,060,000thousands by filing date
ARIAD PHARMACEUTICALS INC04033A100COM1,045,000$14,306,000thousands by filing date
Medgenics Inc New58436Q203COM NEW1,800,000$10,026,000thousands by filing date
AGIOS PHARMACEUTICALS INC00847X104COM130,000$6,867,000thousands by filing date
FIBROGEN INC31572Q808COM330,000$6,831,000thousands by filing date
FOAMIX PHARMACEUTICALS LTDM46135105SHS630,000$5,834,000thousands by filing date
CARA THERAPEUTICS INC140755109COM675,000$5,636,000thousands by filing date
CODEXIS INC192005106COM1,170,000$5,195,000thousands by filing date
CYNAPSUS THERAPEUTICS INC23257Y859COM PAR NO PAR125,000$5,029,000thousands by filing date
HORIZON PHARMA PLCG4617B105SHS275,000$4,986,000thousands by filing date
EAGLE PHARMACEUTICALS INC269796108COM70,000$4,900,000thousands by filing date
IMPRIMIS PHARMA IMMY45323A201COMMON1,215,381$4,631,000thousands by filing date
GLOBAL BLOOD THERAPEUTICS USD37890U108COM200,000$4,610,000thousands by filing date
PROTALIX BIOTHERAPEUTICS INC74365AAB7NOTE 4.500% 9/18,070,000$4,600,000thousands by filing date
MACROGENICS INC556099109COM145,000$4,337,000thousands by filing date
CHIMERIX INC COM16934W106Stock780,000$4,321,000thousands by filing date
AQUINOX PHARMACEUTICALS INC03842B101COM310,000$4,142,000thousands by filing date
ADAMAS PHARMACEUTICALS INC00548A106COM250,000$4,103,000thousands by filing date
IMMUNOMEDICS INC452907108COM1,200,000$3,900,000thousands by filing date
ITEK 5 02/15/2045780VAA0Bond 30/360P2 U400,000$3,792,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock410,000$3,321,000thousands by filing date
PROTHENA CORP PLC SHSG72800108Stock50,000$2,999,000thousands by filing date
EDGE THERAPEUTICS INC279870109COM280,000$2,915,000thousands by filing date
LOXO ONCOLOGY INC548862101COM110,000$2,880,000thousands by filing date
TRILLIUM THERAPEUTICS INC COM NEW89620X506Stock175,000$2,587,000thousands by filing date
ZOGENIX INC98978L105COM220,000$2,515,000thousands by filing date
CYTOMX THERAPEUTICS INC23284F105COMMON STOCK160,000$2,509,000thousands by filing date
ULTRAGENYX PHARMACEUTICAL IN90400D108COM35,000$2,483,000thousands by filing date
PROTEOSTASIS THERAPEUTICS IN74373B109COM152,000$2,370,000thousands by filing date
Lion Biotechnologies53619R102COM280,000$2,304,000thousands by filing date
CORIUM INTL INC21887L107COM400,000$2,252,000thousands by filing date
AMARIN CORP PLC023111206SPONS ADR NEW700,000$2,233,000thousands by filing date
NEURODERM LTDM74231107ORD SHS98,500$1,821,000thousands by filing date
NABRIVA THERAPEUTICS AG62957M104SPONSORED ADR239,500$1,688,000thousands by filing date
INNOCOLL HLDGS PLCG4783X105SHS269,100$1,563,000thousands by filing date
AFFIMED N VN01045108COM430,000$1,195,000thousands by filing date
INTEC PHARMA LTD JERUSALEMM53644106SHS175,000$1,029,000thousands by filing date
TENAX THERAPEUTICS INC88032L100COM390,000$905,000thousands by filing date
PORTOLA PHARMACEUTICALS INC737010908COM35,000$795,000thousands by filing date
ABEONA THERAPEUTICS INC00289Y107COM100,000$600,000thousands by filing date
AMAG PHARMACEUTICALS INC00163U106COM15,000$368,000thousands by filing date
BIOLINERX LTD-SPONS ADR09071M106SPON250,000$288,000thousands by filing date
DEPOMED INC249908104COM1,650$41,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001546927-16-000542this filing2016-11-14acceptance time not in the bulk data set