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13F-HR filed by Opaleye Management Inc.

Opaleye Management Inc. filed this 13F-HR for the quarter ended 2022-03-31, filed 2022-05-16, with 45 holding rows worth $321,996,000.

Accession
0001493152-22-013764
Filed
2022-05-16
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2022

A holdings report, 45 entries on the cover page, a total value of $321,996,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $321,998,000 with VALUE read as thousands by filing date, 13F file number 028-15896. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
OCULAR THERAPEUTIX INC67576A100COM5,974,800$29,575,000thousands by filing date
CODEXIS INC192005106COM1,345,000$27,734,000thousands by filing date
CHIMERIX INC COM16934W106Stock5,903,450$27,038,000thousands by filing date
HARROW INC415858109COM3,291,343$22,447,000thousands by filing date
CRINETICS PHARMACEUTICALS INC COM22663K107Stock693,000$15,211,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW406,500$14,963,000thousands by filing date
KEROS THERAPEUTICS INC COM492327101Stock265,750$14,451,000thousands by filing date
PROTARA THERAPEUTICS INC74365U107COM STK2,674,031$13,664,000thousands by filing date
REATA PHARMACEUTICALS INC75615P103CL A407,002$13,333,000thousands by filing date
KINIKSA PHARMACEUTICALS LTDG5269C101COM CL A1,112,500$11,058,000thousands by filing date
ETON PHARMACEUTICALS INC29772L108COMMON STOCK2,379,275$10,374,000thousands by filing date
MERUS N VN5749R100COM338,000$8,937,000thousands by filing date
STEREOTAXIS INC85916J409COMMON STOCK2,395,600$8,936,000thousands by filing date
TRACON PHARMACEUTICALS INC89237H209COM NEW3,155,098$8,298,000thousands by filing date
BICYCLE THERAPEUTICS PLC-ADR088786108SPONSORED ADS175,000$7,679,000thousands by filing date
XOMA ROYALTY CORPORATION98419J206COMMON STOCK271,000$7,583,000thousands by filing date
CELLDEX THERAPEUTICS INC NEW15117B202COM NEW195,500$6,659,000thousands by filing date
PROTAGONIST THERAPEUTICS74366E102COM251,500$5,956,000thousands by filing date
TELA BIO INC872381108COM477,000$5,548,000thousands by filing date
FORTRESS BIOTECH INC34960Q109COM3,750,000$5,100,000thousands by filing date
VAXCYTE INC COM92243G108Stock211,000$5,096,000thousands by filing date
4D MOLECULAR THERAPEUTICS INC COM35104E100Stock325,000$4,914,000thousands by filing date
LARIMAR THERAPEUTICS INC517125100COM943,702$3,822,000thousands by filing date
GINKGO BIOWORKS HOLDINGS INC37611X100CL A SHS929,780$3,747,000thousands by filing date
SEMLER SCIENTIFIC INC81684M104COM70,000$3,469,000thousands by filing date
MACROGENICS INC556099109COM376,400$3,316,000thousands by filing date
VERASTEM INC92337C104COM2,325,000$3,278,000thousands by filing date
FULCRUM THERAPEUTICS INC359616109COMMON STOCK136,000$3,216,000thousands by filing date
908 DEVICES INC COM65443P102Stock166,406$3,163,000thousands by filing date
EDGEWISE THERAPEUTICS INC28036F105COM303,000$2,939,000thousands by filing date
Mersana Therapeutics Inc59045L106Common Stock710,000$2,833,000thousands by filing date
HYPERFINE INC44916K106Common Stock763,075$2,701,000thousands by filing date
SYNLOGIC INC87166L100COM984,200$2,362,000thousands by filing date
PROQR THERAPEUTICS NVN71542109SHS EURO2,425,000$2,195,000thousands by filing date
NEOLEUKIN THERAPEUTICS INC64049K104COM790,000$1,485,000thousands by filing date
AVEO PHARMACEUTICALS INC053588307COM240,000$1,342,000thousands by filing date
GRAPHITE BIO INC38870X104COM255,500$1,303,000thousands by filing date
LIQUIDIA CORPORATION COM NEW53635D202Stock178,800$1,284,000thousands by filing date
MODULAR MED INC60785L207COM NEW266,100$1,171,000thousands by filing date
AVALO THERAPEUTICS INC05338F108CMN1,454,400$1,054,000thousands by filing date
NUCANA PLC67022C106ADR878,700$878,000thousands by filing date
REPARE THERAPEUTICS INC760273102COM55,678$793,000thousands by filing date
SUTRO BIOPHARMA INC869367102COM89,980$740,000thousands by filing date
JOURNEY MED CORP48115J109COM67,000$324,000thousands by filing date
NULL09071M205NULL16,667$29,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001493152-22-013764this filing2022-05-16acceptance time not in the bulk data set