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13F-HR filed by Opaleye Management Inc.

Opaleye Management Inc. filed this 13F-HR for the quarter ended 2019-12-31, filed 2020-02-14, with 47 holding rows worth $509,649,000.

Accession
0001493152-20-002529
Filed
2020-02-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2019

A holdings report, 47 entries on the cover page, a total value of $509,649,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $509,651,000 with VALUE read as thousands by filing date, 13F file number 028-15896. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
EPIZYME INC29428V104COM1,384,200$34,051,000thousands by filing date
APTOSE BIOSCIENCES INC COM03835T200Stock4,085,000$23,162,000thousands by filing date
CODEXIS INC192005106COM1,400,000$22,286,000thousands by filing date
FORTY SEVEN INC34983P104COM562,000$22,126,000thousands by filing date
STEREOTAXIS INC85916J409COMMON STOCK4,112,500$22,025,000thousands by filing date
TURNING PT THERAPEUTICS90041T108COM340,500$21,210,000thousands by filing date
OCULAR THERAPEUTIX INC67576A100COM5,107,500$20,175,000thousands by filing date
IMPRIMIS PHARMA IMMY45323A201COMMON2,340,000$18,205,000thousands by filing date
EIDOS THERAPEUTICS INC.28249H104Common Stock315,550$18,109,000thousands by filing date
AUDENTES THERAPEUTICS INC.05070R104Common Stock292,000$17,473,000thousands by filing date
NEOLEUKIN THERAPEUTICS INC64049K104COM1,381,300$17,018,000thousands by filing date
UNIQURE NVN90064101SHS210,000$15,049,000thousands by filing date
AMARIN CORP PLC023111206SPONS ADR NEW665,000$14,258,000thousands by filing date
DECIPHERA PHARMACEUTICALS IN24344T101COM224,500$13,973,000thousands by filing date
INTRA-CELLULAR THERAPIES INC46116X101COMMON STOCK406,600$13,950,000thousands by filing date
CHEMOCENTRYX INC16383L106COM361,600$13,846,000thousands by filing date
AXOGEN INC05463X106COM700,000$12,523,000thousands by filing date
CERECOR INC15671L109COM2,190,674$11,808,000thousands by filing date
ODONATE THERAPEUTICS INC676079106COM355,000$11,520,000thousands by filing date
ETON PHARMACEUTICALS INC29772L108COMMON STOCK1,469,456$10,580,000thousands by filing date
XOMA ROYALTY CORPORATION98419J206COMMON STOCK373,450$10,195,000thousands by filing date
AVENUE THERAPEUTICS INC05360L205COM1,035,000$9,936,000thousands by filing date
FORTRESS BIOTECH INC034960Q19COM3,825,100$9,831,000thousands by filing date
PTC THERAPEUTICS INC69366J200COM191,000$9,174,000thousands by filing date
BIOHAVEN PHARMACEUTICAL HOLDING11196105COM165,000$8,983,000thousands by filing date
ACADIA PHARMACEUTICALS INC004225108COM206,500$8,834,000thousands by filing date
FLEXION THERAPEUTICS INC33938J106COM415,500$8,601,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM100,000$8,001,000thousands by filing date
ZYMEWORKS INC98985W102COM175,000$7,956,000thousands by filing date
EDAP TMS S A268311107SPONSORED ADR1,785,000$7,908,000thousands by filing date
TRICIDA INC89610F101COM194,000$7,303,000thousands by filing date
DIANTHUS THERAPEUTICS INC COM55910K108Stock449,950$6,728,000thousands by filing date
CRINETICS PHARMACEUTICALS INC COM22663K107Stock266,100$6,676,000thousands by filing date
RA PHARMACEUTICALS INC74933V108COM141,800$6,655,000thousands by filing date
TG THERAPEUTICS INC COM88322Q108Stock579,651$6,434,000thousands by filing date
FIBROGEN INC31572Q808COM146,000$6,262,000thousands by filing date
ACHILLION PHARMACEUTICALS IN00448Q201COM760,000$4,583,000thousands by filing date
AQUESTIVE THERAPEUTICS INC COM03843E104Stock738,500$4,298,000thousands by filing date
KADMON HLDGS INC48283N106COM940,373$4,260,000thousands by filing date
RADIUS HEALTH INC750469207COM NEW168,000$3,387,000thousands by filing date
QUANTERIX CORP74766Q101COMMON STOCK132,200$3,124,000thousands by filing date
RHYTHM PHARMACEUTICALS INC76243J105COM110,500$2,537,000thousands by filing date
TELA BIO INC872381108COM175,000$2,266,000thousands by filing date
MACROGENICS INC556099109COM200,500$2,181,000thousands by filing date
FENNEC PHARMACEUTICALS INC31447P100COMMON STOCK12,000$78,000thousands by filing date
PROTEON THERAPEUTICS INC74371L109COM188,144$75,000thousands by filing date
BIOLINERX LTD-SPONS ADR09071M106SPON16,667$38,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001493152-20-002529this filing2020-02-14acceptance time not in the bulk data set