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13F-HR/A filed by Opaleye Management Inc.

Opaleye Management Inc. filed this 13F-HR/A for the quarter ended 2016-03-31, filed 2016-05-27, with 52 holding rows worth $160,362,000.

Accession
0001546927-16-000499
Filed
2016-05-27
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2016

A holdings report, amendment of type restatement, 52 entries on the cover page, a total value of $160,362,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $160,362,000 with VALUE read as thousands by filing date, 13F file number 028-15896. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
AXOGEN INC05463X106COM2,120,000$11,363,000thousands by filing date
ARIAD PHARMACEUTICALS INC04033A100COM1,250,000$7,988,000thousands by filing date
ULTRAGENYX PHARMACEUTICAL IN90400D108COM110,000$6,964,000thousands by filing date
FIBROGEN INC31572Q808COM325,000$6,919,000thousands by filing date
PROTALIX BIOTHERAPEUTICS INC74365AAB7NOTE 4.500% 9/18,200,000$6,892,000thousands by filing date
Medgenics Inc New58436Q203COM NEW1,557,700$6,854,000thousands by filing date
ADAMAS PHARMACEUTICALS INC00548A106COM320,000$6,064,000thousands by filing date
CARA THERAPEUTICS INC140755109COM855,000$5,318,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM165,000$5,290,000thousands by filing date
AMAG PHARMACEUTICALS INC00163U106COM220,000$5,148,000thousands by filing date
IMPRIMIS PHARMA IMMY45323A201COMMON1,250,000$4,963,000thousands by filing date
ITEK 5 02/15/2045780VAA0Bond 30/360P2 U645,000$4,773,000thousands by filing date
DEPOMED INC249908104COM325,000$4,527,000thousands by filing date
AGIOS PHARMACEUTICALS INC00847X104COM105,000$4,263,000thousands by filing date
EAGLE PHARMACEUTICALS INC838828509COM1,440,000$4,118,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM220,000$3,971,000thousands by filing date
GERON CORP374163103COM1,325,000$3,869,000thousands by filing date
FOAMIX PHARMACEUTICALS LTDM46135105SHS590,000$3,847,000thousands by filing date
CODEXIS INC192005106COM1,178,500$3,665,000thousands by filing date
TG THERAPEUTICS INC COM88322Q108Stock415,000$3,536,000thousands by filing date
CHIMERIX INC COM16934W106Stock675,000$3,449,000thousands by filing date
OPHTHOTECH CORP683745103COM80,000$3,382,000thousands by filing date
IMMUNOMEDICS INC452907108COM1,325,000$3,313,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock400,000$2,796,000thousands by filing date
AMARIN CORP PLC023111206SPONS ADR NEW1,760,000$2,693,000thousands by filing date
INTEC PHARMA LTD JERUSALEMM53644106SHS638,000$2,629,000thousands by filing date
NABRIVA THERAPEUTICS AG62957M104SPONSORED ADR273,800$2,453,000thousands by filing date
EAGLE PHARMACEUTICALS INC269796108COM60,000$2,430,000thousands by filing date
AFFIMED N VN01045108COM610,000$2,281,000thousands by filing date
ZOGENIX INC.98978L204Common Stock240,000$2,218,000thousands by filing date
RETROPHIN INC761299106COM150,000$2,049,000thousands by filing date
SUPERNUS PHARMACEUTICALS868459108COM125,000$1,906,000thousands by filing date
TRILLIUM THERAPEUTICS INC COM NEW89620X506Stock195,000$1,804,000thousands by filing date
EDGE THERAPEUTICS INC279870109COM185,000$1,693,000thousands by filing date
CYNAPSUS THERAPEUTICS INC23257Y859COM PAR NO PAR121,000$1,440,000thousands by filing date
ADAPTIMMUNE THERAPEUTICS PLC00653A107SPONDS ADR175,300$1,425,000thousands by filing date
CORIUM INTL INC21887L107COM360,000$1,390,000thousands by filing date
AURIS MED HLDG AGH03579101COM340,000$1,238,000thousands by filing date
OHR PHARMACEUTICAL INC67778H200COMMON STOCK366,000$1,175,000thousands by filing date
PROTEON THERAPEUTICS INC7437IL109COM150,000$1,161,000thousands by filing date
XOMA CORP DEL98419J107COM1,350,000$1,044,000thousands by filing date
TENAX THERAPEUTICS INC88032L100COM499,600$1,024,000thousands by filing date
ACHAOGEN INC004449104COM255,000$704,000thousands by filing date
NEKTAR THERAPEUTICS640268108COM50,000$688,000thousands by filing date
MEDIVATION INC58501N101COM14,500$667,000thousands by filing date
EVOKE PHARMA INC30049G104COM130,000$662,000thousands by filing date
PROTHENA CORP PLC SHSG72800108Stock14,000$576,000thousands by filing date
NEURODERM LTDM74231107ORD SHS38,500$544,000thousands by filing date
NIVALIS THERAPEUTICS INC65481J109COM100,000$417,000thousands by filing date
ACLARIS THERAPEUTICS INC COM00461U105Stock18,000$341,000thousands by filing date
BIOLINERX LTD-SPONS ADR09071M106SPON250,000$255,000thousands by filing date
CHIASMA INC16706W102COM20,000$183,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001546927-16-000493 superseded2016-05-16acceptance time not in the bulk data set
13F-HR/A 0001546927-16-000499this filing2016-05-27acceptance time not in the bulk data set