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13F-HR filed by Opaleye Management Inc.

Opaleye Management Inc. filed this 13F-HR for the quarter ended 2018-09-30, filed 2018-11-14, with 47 holding rows worth $393,047,000.

Accession
0001493152-18-016123
Filed
2018-11-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q3 2018

A holdings report, 47 entries on the cover page, a total value of $393,047,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $393,047,000 with VALUE read as thousands by filing date, 13F file number 028-15896. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
AXOGEN INC05463X106COM1,300,000$47,905,000thousands by filing date
CODEXIS INC192005106COM1,750,000$30,012,000thousands by filing date
LOXO ONCOLOGY INC548862101COM175,000$29,895,000thousands by filing date
AMARIN CORP PLC023111206SPONS ADR NEW1,600,000$26,032,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM300,000$23,418,000thousands by filing date
DECIPHERA PHARMACEUTICALS IN24344T101COM420,000$16,262,000thousands by filing date
POLARITYTE INC731094108COM765,000$14,611,000thousands by filing date
VIKING THERAPEUTICS INC92686J106COM825,000$14,371,000thousands by filing date
FIBROGEN INC31572Q808COM200,000$12,150,000thousands by filing date
AGIOS PHARMACEUTICALS INC00847X104COM130,000$10,025,000thousands by filing date
AUDENTES THERAPEUTICS INC.05070R104Common Stock225,000$8,907,000thousands by filing date
DIANTHUS THERAPEUTICS INC COM55910K108Stock725,000$8,707,000thousands by filing date
PTC THERAPEUTICS INC69366J200COM180,000$8,460,000thousands by filing date
AMAG PHARMACEUTICALS INC00163U106COM420,000$8,400,000thousands by filing date
STRONGBRIDGE BIOPHARMA PLCG85347105SHS USD1,730,000$8,390,000thousands by filing date
SANGAMO THERAPEUTICS INC800677106COM490,000$8,305,000thousands by filing date
FENNEC PHARMACEUTICALS INC31447P100COMMON STOCK975,000$7,995,000thousands by filing date
MIRAGEN THERAPEUTICS INC60463E103COM1,395,700$7,788,000thousands by filing date
CYMABAY THERAPEUTICS INC23257D103COM698,100$7,735,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock465,200$7,014,000thousands by filing date
APELLIS PHARMACEUTICALS INC03753U106COM375,000$6,667,000thousands by filing date
XENCOR INC98401F105COMMON STOCK180,000$6,140,000thousands by filing date
ULTRAGENYX PHARMACEUTICAL IN90400D108COM80,000$6,107,000thousands by filing date
XOMA ROYALTY CORPORATION98419J206COMMON STOCK320,000$5,622,000thousands by filing date
OCULAR THERAPEUTIX INC67576A100COM800,000$5,504,000thousands by filing date
CIDARA THERAPEUTICS INC COM NEW171757107Stock1,200,000$5,280,000thousands by filing date
CORIUM INTL INC21887L107COM550,000$5,230,000thousands by filing date
CHIMERIX INC COM16934W106Stock1,185,000$4,609,000thousands by filing date
IMPRIMIS PHARMA IMMY45323A201COMMON1,620,000$4,503,000thousands by filing date
ACADIA PHARMACEUTICALS INC004225108COM195,000$4,048,000thousands by filing date
IOVANCE BIOTHERAPEUTICS INC462260100COM325,000$3,656,000thousands by filing date
CTI BIOPHARMA CORP12648L601COM1,550,000$3,348,000thousands by filing date
CARA THERAPEUTICS INC140755109COM130,000$3,113,000thousands by filing date
ARQULE INC04269E107COM550,000$3,113,000thousands by filing date
CELLECTIS ADS15117K103COM110,000$3,104,000thousands by filing date
ARDELYX INC039697107COM650,000$2,827,000thousands by filing date
EPIZYME INC29428V104COM200,000$2,120,000thousands by filing date
TG THERAPEUTICS INC COM88322Q108Stock350,000$1,960,000thousands by filing date
PROTALIX BIOTHERAPEUTICS INC74365A101COM2,500,000$1,817,000thousands by filing date
CLEMENTIA PHARMACEUTICALS IN185575107COM148,832$1,660,000thousands by filing date
TRICIDA INC89610F101COM51,000$1,558,000thousands by filing date
BIOFRONTERA AG ADR09075G105COM79,007$1,073,000thousands by filing date
DERMIRA INC24983L104COM97,400$1,061,000thousands by filing date
ACHILLION PHARMACEUTICALS IN00448Q201COM275,000$1,012,000thousands by filing date
INFINITY PHARMACEUTICALS INC45665G303COM275,000$745,000thousands by filing date
FOAMIX PHARMACEUTICALS LTDM46135105SHS91,000$521,000thousands by filing date
BIOLINERX LTD-SPONS ADR09071M106SPON250,000$267,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001493152-18-016123this filing2018-11-14acceptance time not in the bulk data set