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13F-HR filed by Opaleye Management Inc.

Opaleye Management Inc. filed this 13F-HR for the quarter ended 2016-06-30, filed 2016-08-12, with 49 holding rows worth $149,709,000.

Accession
0001546927-16-000512
Filed
2016-08-12
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q2 2016

A holdings report, 49 entries on the cover page, a total value of $149,709,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $149,709,000 with VALUE read as thousands by filing date, 13F file number 028-15896. A later restatement replaced it, so the quarter does not use it. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
AURIS MED HLDG AGH03579101COM2,120,000$14,586,000thousands by filing date
NABRIVA THERAPEUTICS AG62957M104SPONSORED ADR1,950,000$10,823,000thousands by filing date
AMARIN CORP PLC023111206SPONS ADR NEW1,250,000$9,238,000thousands by filing date
EDGE THERAPEUTICS INC279870109COM330,000$5,415,000thousands by filing date
OPHTHOTECH CORP683745103COM8,200,000$5,248,000thousands by filing date
BIOLINERX LTD-SPONS ADR09071M106SPON250,000$5,063,000thousands by filing date
ITEK 5 02/15/2045780VAA0Bond 30/360P2 U645,000$4,799,000thousands by filing date
IMMUNOMEDICS INC452907108COM1,267,500$4,766,000thousands by filing date
CHIMERIX INC COM16934W106Stock1,178,500$4,749,000thousands by filing date
ACHAOGEN INC004449104COM300,000$4,542,000thousands by filing date
EVOKE PHARMA INC30049G104COM695,000$4,413,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM835,000$4,016,000thousands by filing date
AGIOS PHARMACEUTICALS INC00847X104COM1,760,000$3,802,000thousands by filing date
ADAPTIMMUNE THERAPEUTICS PLC00653A107SPONDS ADR85,000$3,561,000thousands by filing date
FOAMIX PHARMACEUTICALS LTDM46135105SHS200,000$3,294,000thousands by filing date
ULTRAGENYX PHARMACEUTICAL IN90400D108COM65,000$3,179,000thousands by filing date
MEDIVATION INC58501N101COM112,000$3,023,000thousands by filing date
GERON CORP374163103COM1,300,000$3,016,000thousands by filing date
INTEC PHARMA LTD JERUSALEMM53644106SHS650,000$2,989,000thousands by filing date
AFFIMED N VN01045108COM120,000$2,870,000thousands by filing date
CARA THERAPEUTICS INC140755109COM675,000$2,653,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM125,000$2,546,000thousands by filing date
FIBROGEN INC31572Q808COM152,000$2,522,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock410,000$2,419,000thousands by filing date
DEPOMED INC249908104COM225,600$2,281,000thousands by filing date
Medgenics Inc New58436Q203COM NEW260,000$2,106,000thousands by filing date
CORIUM INTL INC21887L107COM125,000$2,094,000thousands by filing date
OHR PHARMACEUTICAL INC67778H200COMMON STOCK146,700$2,041,000thousands by filing date
NEKTAR THERAPEUTICS640268108COM270,000$2,025,000thousands by filing date
AMAG PHARMACEUTICALS INC00163U106COM295,000$1,953,000thousands by filing date
EAGLE PHARMACEUTICALS INC838828509COM50,000$1,940,000thousands by filing date
XOMA CORP DEL98419J107COM240,000$1,932,000thousands by filing date
TRILLIUM THERAPEUTICS INC COM NEW89620X506Stock195,000$1,751,000thousands by filing date
RETROPHIN INC761299106COM57,500$1,670,000thousands by filing date
CYNAPSUS THERAPEUTICS INC23257Y859COM PAR NO PAR160,000$1,634,000thousands by filing date
TG THERAPEUTICS INC COM88322Q108Stock800,000$1,592,000thousands by filing date
ADAMAS PHARMACEUTICALS INC00548A106COM595,000$1,476,000thousands by filing date
IMPRIMIS PHARMA IMMY45323A201COMMON265,000$1,460,000thousands by filing date
ARIAD PHARMACEUTICALS INC04033A100COM340,000$1,425,000thousands by filing date
NIVALIS THERAPEUTICS INC65481J109COM260,000$1,287,000thousands by filing date
PROTALIX BIOTHERAPEUTICS INC74365AAB7NOTE 4.500% 9/1105,000$1,274,000thousands by filing date
CODEXIS INC192005106COM360,000$1,249,000thousands by filing date
SUPERNUS PHARMACEUTICALS868459108COM465,000$1,190,000thousands by filing date
TENAX THERAPEUTICS INC88032L100COM175,000$1,061,000thousands by filing date
EAGLE PHARMACEUTICALS INC269796108COM130,000$891,000thousands by filing date
NEURODERM LTDM74231107ORD SHS52,500$853,000thousands by filing date
CHIASMA INC16706W102COM43,000$443,000thousands by filing date
ACLARIS THERAPEUTICS INC COM00461U105Stock40,000$326,000thousands by filing date
AXOGEN INC05463X106COM250,000$223,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001546927-16-000512this filing2016-08-12acceptance time not in the bulk data set
13F-HR/A 0001546927-16-000514 base2016-08-12acceptance time not in the bulk data set