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13F-HR filed by Opaleye Management Inc.

Opaleye Management Inc. filed this 13F-HR for the quarter ended 2021-09-30, filed 2021-11-16, with 48 holding rows worth $535,386,000.

Accession
0001493152-21-028799
Filed
2021-11-16
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q3 2021

A holdings report, 48 entries on the cover page, a total value of $535,386,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $535,390,000 with VALUE read as thousands by filing date, 13F file number 028-15896. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
OCULAR THERAPEUTIX INC67576A100COM6,480,000$64,800,000thousands by filing date
CELLDEX THERAPEUTICS INC NEW15117B202COM NEW985,000$53,045,000thousands by filing date
CODEXIS INC192005106COM1,345,000$31,285,000thousands by filing date
CHIMERIX INC COM16934W106Stock5,030,000$31,136,000thousands by filing date
HARROW INC415858109COM3,285,000$29,861,000thousands by filing date
SEMLER SCIENTIFIC INC81684M104COM225,566$28,203,000thousands by filing date
BRIDGEBIO PHARMA INC10806X102COM511,500$23,974,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW580,000$20,729,000thousands by filing date
PROTARA THERAPEUTICS INC74365U107COM STK2,558,472$17,705,000thousands by filing date
ETON PHARMACEUTICALS INC29772L108COMMON STOCK3,088,100$15,564,000thousands by filing date
KINIKSA PHARMACEUTICALS LTDG5269C101COM CL A1,310,000$14,921,000thousands by filing date
KEROS THERAPEUTICS INC COM492327101Stock352,500$13,945,000thousands by filing date
STEREOTAXIS INC85916J409COMMON STOCK2,526,500$13,593,000thousands by filing date
FORTRESS BIOTECH INC34960Q109COM3,750,000$12,075,000thousands by filing date
PROQR THERAPEUTICS NVN71542109SHS EURO1,424,200$11,921,000thousands by filing date
SUTRO BIOPHARMA INC869367102COM537,800$10,159,000thousands by filing date
TRACON PHARMACEUTICALS INC89237H209COM NEW2,518,371$9,746,000thousands by filing date
MACROGENICS INC556099109COM462,000$9,674,000thousands by filing date
LARIMAR THERAPEUTICS INC517125100COM832,807$9,602,000thousands by filing date
VAXCYTE INC COM92243G108Stock353,400$8,966,000thousands by filing date
CRINETICS PHARMACEUTICALS INC COM22663K107Stock402,113$8,464,000thousands by filing date
XOMA ROYALTY CORPORATION98419J206COMMON STOCK338,350$8,374,000thousands by filing date
NEOLEUKIN THERAPEUTICS INC64049K104COM1,047,300$7,572,000thousands by filing date
ADAMAS PHARMACEUTICALS INC00548A106COM1,460,000$7,169,000thousands by filing date
VERASTEM INC92337C104COM2,325,000$7,161,000thousands by filing date
DECIPHERA PHARMACEUTICALS IN24344T101COM205,381$6,979,000thousands by filing date
TELA BIO INC872381108COM443,199$6,054,000thousands by filing date
PROTAGONIST THERAPEUTICS74366E102COM330,222$5,852,000thousands by filing date
ACUTUS MED INC005111109COM590,000$5,216,000thousands by filing date
OPTINOSE INC68404V100COM1,558,500$4,676,000thousands by filing date
MEI PHARMA INC55279B202COM NEW1,565,000$4,319,000thousands by filing date
FORMA THERAPEUTICS HLDGS INC34633R104SHS182,950$4,243,000thousands by filing date
SIERRA ONCOLOGY INC82640U404CMN165,778$3,634,000thousands by filing date
AVALO THERAPEUTICS INC05338F108CMN1,459,400$3,181,000thousands by filing date
AMICUS THERAPEUTICS INC03152W109COM320,800$3,064,000thousands by filing date
AVEO PHARMACEUTICALS INC053588307COM455,600$2,816,000thousands by filing date
MERUS N VN5749R100COM100,250$2,206,000thousands by filing date
VIRACTA THERAPEUTICS INC92765F108COM258,556$2,074,000thousands by filing date
SIO GENE THERAPIES INC829399104COM955,000$2,072,000thousands by filing date
LEAP THERAPEUTICS INC52187K101COM476,000$1,909,000thousands by filing date
PRECISION BIOSCIENCES INC74019P108COM163,900$1,891,000thousands by filing date
WHITEHAWK THERAPEUTICS INC00032Q104CMN45,020$1,322,000thousands by filing date
NUCANA PLC67022C106ADR479,600$1,237,000thousands by filing date
APTOSE BIOSCIENCES INC COM03835T200Stock549,000$1,197,000thousands by filing date
AKEBIA THERAPEUTICS INC00972D105COMMON STOCK311,300$897,000thousands by filing date
SELECTA BIOSCIENCES INC816212104COM106,000$441,000thousands by filing date
CYMABAY THERAPEUTICS INC23257D103COM115,015$420,000thousands by filing date
NULL09071M205NULL16,667$46,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001493152-21-028799this filing2021-11-16acceptance time not in the bulk data set