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13F-HR filed by Opaleye Management Inc.

Opaleye Management Inc. filed this 13F-HR for the quarter ended 2019-03-31, filed 2019-05-15, with 53 holding rows worth $361,130,000.

Accession
0001493152-19-007425
Filed
2019-05-15
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2019

A holdings report, 53 entries on the cover page, a total value of $361,130,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $361,134,000 with VALUE read as thousands by filing date, 13F file number 028-15896. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
CODEXIS INC192005106COM1,475,000$30,282,000thousands by filing date
AXOGEN INC05463X106COM1,100,000$23,166,000thousands by filing date
EPIZYME INC29428V104COM1,365,000$16,912,000thousands by filing date
CERECOR INC15671L109COM2,300,000$13,432,000thousands by filing date
AMARIN CORP PLC023111206SPONS ADR NEW645,000$13,390,000thousands by filing date
UNIQURE NVN90064101SHS205,000$12,228,000thousands by filing date
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR95,000$11,182,000thousands by filing date
TG THERAPEUTICS INC COM88322Q108Stock1,366,062$10,983,000thousands by filing date
AUDENTES THERAPEUTICS INC.05070R104Common Stock280,000$10,926,000thousands by filing date
FIBROGEN INC31572Q808COM200,000$10,870,000thousands by filing date
CLEMENTIA PHARMACEUTICALS IN185575107COM400,130$10,443,000thousands by filing date
BLUEPRINT MEDICINES CORP09627Y109COM130,000$10,407,000thousands by filing date
INVITAE CORP46185L103COM440,000$10,305,000thousands by filing date
CATALYST PHARMACEUTICALS INC14888U101COM1,825,000$9,308,000thousands by filing date
IMPRIMIS PHARMA IMMY45323A201COMMON1,800,000$8,964,000thousands by filing date
DIANTHUS THERAPEUTICS INC COM55910K108Stock510,000$8,400,000thousands by filing date
PTC THERAPEUTICS INC69366J200COM213,800$8,047,000thousands by filing date
DECIPHERA PHARMACEUTICALS IN24344T101COM340,000$7,891,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM105,000$7,697,000thousands by filing date
OCULAR THERAPEUTIX INC67576A100COM1,900,000$7,543,000thousands by filing date
CYMABAY THERAPEUTICS INC23257D103COM550,000$7,304,000thousands by filing date
ODONATE THERAPEUTICS INC676079106COM325,000$7,186,000thousands by filing date
CYTOKINETICS INC23282W905COM NEW850,000$6,877,000thousands by filing date
TRICIDA INC89610F101COM165,000$6,372,000thousands by filing date
ETON PHARMACEUTICALS INC29772L108COMMON STOCK764,773$6,118,000thousands by filing date
STRONGBRIDGE BIOPHARMA PLCG85347105SHS USD1,152,500$5,739,000thousands by filing date
DERMIRA INC24983L104COM400,000$5,420,000thousands by filing date
ACADIA PHARMACEUTICALS INC004225108COM200,000$5,370,000thousands by filing date
XOMA ROYALTY CORPORATION98419J206COMMON STOCK400,000$4,952,000thousands by filing date
HORIZON PHARMA PLCG4617B105SHS185,000$4,890,000thousands by filing date
VIKING THERAPEUTICS INC92686J106COM485,000$4,821,000thousands by filing date
EIDOS THERAPEUTICS INC.28249H104Common Stock200,000$4,690,000thousands by filing date
RETROPHIN INC761299106COM205,000$4,639,000thousands by filing date
ABEONA THERAPEUTICS INC00289Y107COM560,000$4,122,000thousands by filing date
CARA THERAPEUTICS INC140755109COM200,000$3,924,000thousands by filing date
AVENUE THERAPEUTICS INC05360L205COM800,000$3,800,000thousands by filing date
AIMMUNE THERAPEUTICS INC.00900T107Common Stock165,000$3,688,000thousands by filing date
FORTRESS BIOTECH INC034960Q19COM2,000,000$3,560,000thousands by filing date
ACORDA THERAPEUTICS INC00484M106COM265,000$3,522,000thousands by filing date
SHOCKWAVE MED INC82489T104COM92,100$3,083,000thousands by filing date
FENNEC PHARMACEUTICALS INC31447P100COMMON STOCK630,000$3,056,000thousands by filing date
CIDARA THERAPEUTICS INC COM NEW171757107Stock1,000,000$2,650,000thousands by filing date
LIQUIDIA CORPORATION COM NEW53635D202Stock225,000$2,561,000thousands by filing date
APELLIS PHARMACEUTICALS INC03753U106COM115,000$2,243,000thousands by filing date
CHIMERIX INC COM16934W106Stock960,000$2,016,000thousands by filing date
CRINETICS PHARMACEUTICALS INC COM22663K107Stock73,000$1,661,000thousands by filing date
ESTABLISHMENT LABS HOLDINGSG31249108COMMON STOCK50,000$1,202,000thousands by filing date
ZYMEWORKS INC98985W102COM55,000$890,000thousands by filing date
SYNTHORX INC COM87167A103Stock40,000$815,000thousands by filing date
FOAMIX PHARMACEUTICALS LTDM46135105SHS180,000$675,000thousands by filing date
KURA ONCOLOGY INC COM50127T109Stock25,200$418,000thousands by filing date
LA JOLLA PHARMACEUTICAL CO503459604COM PAR $.0001 260,000$386,000thousands by filing date
BIOLINERX LTD-SPONS ADR09071M106SPON250,000$108,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001493152-19-007425this filing2019-05-15acceptance time not in the bulk data set