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STEMPOINT CAPITAL LP

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13F filer, CIK 1952142, NEW YORK, NY

STEMPOINT CAPITAL LP reported $583,203,176 across 77 holdings for the quarter ended 2025-12-31, in a 13F-HR filed 2026-02-17. Its ten largest share positions make up 45.68% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001420506-26-000490

Period
2025-12-31
Reported value
$583M
Holdings
77
Top 10 weight
45.68%
New
32
Sold out
42

Largest buys vs the previous quarter

SecurityShares changeApprox. value
ABVXadded+225,510$30.4M
ACLXadded+321,484$21M
TWSTnew+518,355$16.4M
GPCRadded+221,738$15.4M
TERNadded+339,581$13.7M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
ROIVreduced-3,230,489-$70.1M
IMVTreduced-944,621-$24M
DNLIreduced-1,315,601-$21.7M
WVEexited-2,110,152-$15.4M
BHVNexited-1,017,311-$15.3M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q4 2025

Share positions as resolved from 13F-HR 0001420506-26-000490, largest first. % of portfolio is the value over $582,692,176, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
ABVXABIVAX SAQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 87,748 shares; 2025Q3: 166,273 shares; 2025Q4: 391,783 shares 391,783$52.8M9.07%+225,510Timeline
SRRKSCHOLAR ROCK HLDG CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 166,307 shares; 2025Q1: 566,212 shares; 2025Q2: 528,115 shares; 2025Q3: 726,204 shares; 2025Q4: 886,893 shares 886,893$39.1M6.7%+160,689Timeline
CNTACENTESSA PHARMACEUTICALS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 83,662 shares; 2024Q4: 641,964 shares; 2025Q1: 593,335 shares; 2025Q2: 1,265,672 shares; 2025Q3: 655,385 shares; 2025Q4: 1,154,114 shares 1,154,114$28.9M4.95%+498,729Timeline
SNDXSYNDAX PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,731,191 shares; 2024Q4: 2,872,601 shares; 2025Q1: 1,598,594 shares; 2025Q2: 2,372,634 shares; 2025Q3: 1,366,205 shares; 2025Q4: 1,339,379 shares 1,339,379$28.1M4.83%-26,826Timeline
GPCRSTRUCTURE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 129,335 shares; 2025Q4: 351,073 shares 351,073$24.4M4.19%+221,738Timeline
ACLXARCELLX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 60,076 shares; 2024Q4: not reported; 2025Q1: 273,774 shares; 2025Q2: 201,452 shares; 2025Q3: 11,376 shares; 2025Q4: 332,860 shares 332,860$21.7M3.72%+321,484Timeline
ROIVROIVANT SCIENCES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,769,819 shares; 2024Q4: 2,712,778 shares; 2025Q1: 2,578,860 shares; 2025Q2: 601,781 shares; 2025Q3: 4,197,187 shares; 2025Q4: 966,698 shares 966,698$21M3.6%-3,230,489Timeline
TERNTERNS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 449,321 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 89,617 shares; 2025Q4: 429,198 shares 429,198$17.3M2.98%+339,581Timeline
TWSTTWIST BIOSCIENCE CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 518,355 shares 518,355$16.4M2.82%newTimeline
IMVTIMMUNOVANT INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 671,001 shares; 2024Q4: 1,118,508 shares; 2025Q1: 853,472 shares; 2025Q2: 1,300,860 shares; 2025Q3: 1,589,580 shares; 2025Q4: 644,959 shares 644,959$16.4M2.81%-944,621Timeline
DYNDYNE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 84,430 shares; 2025Q2: not reported; 2025Q3: 474,612 shares; 2025Q4: 835,200 shares 835,200$16.3M2.8%+360,588Timeline
XENEXENON PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 375,845 shares; 2025Q1: 274,633 shares; 2025Q2: not reported; 2025Q3: 192,295 shares; 2025Q4: 348,605 shares 348,605$15.6M2.68%+156,310Timeline
SRZNSURROZEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 182,918 shares; 2024Q4: 350,573 shares; 2025Q1: 240,826 shares; 2025Q2: 686,539 shares; 2025Q3: 713,463 shares; 2025Q4: 619,766 shares 619,766$12.7M2.17%-93,697Timeline
CELCCELCUITY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 136,710 shares; 2025Q4: 118,333 shares 118,333$11.8M2.03%-18,377Timeline
MLYSMINERALYS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 400,101 shares; 2025Q1: not reported; 2025Q2: 631,586 shares; 2025Q3: 158,112 shares; 2025Q4: 290,049 shares 290,049$10.5M1.81%+131,937Timeline
MDGLMADRIGAL PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 40,936 shares; 2025Q2: 52,694 shares; 2025Q3: 8,207 shares; 2025Q4: 17,736 shares 17,736$10.3M1.77%+9,529Timeline
ADPTADAPTIVE BIOTECHNOLOGIES CORQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 606,825 shares 606,825$9.85M1.69%newTimeline
PALIPALISADE BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 4,192,375 shares 4,192,375$9.85M1.69%newTimeline
CYTKCYTOKINETICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 14,464 shares; 2024Q4: 83,576 shares; 2025Q1: 149,648 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 146,978 shares 146,978$9.34M1.6%newTimeline
EWTXEDGEWISE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 19,900 shares; 2024Q4: 132,706 shares; 2025Q1: 180,255 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 360,876 shares 360,876$8.96M1.54%newTimeline
DRUGBRIGHT MINDS BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 97,340 shares 97,340$7.6M1.3%newTimeline
NKTRNEKTAR THERAPEUTICSQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 53,201 shares; 2025Q4: 178,274 shares 178,274$7.54M1.29%+125,073Timeline
JNJJOHNSON & JOHNSONQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 35,000 shares 35,000$7.24M1.24%newTimeline
DNLIDENALI THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 282,050 shares; 2024Q4: 584,328 shares; 2025Q1: 667,078 shares; 2025Q2: 707,915 shares; 2025Q3: 1,734,659 shares; 2025Q4: 419,058 shares 419,058$6.92M1.19%-1,315,601Timeline
AMLXAMYLYX PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 276,884 shares; 2025Q4: 565,140 shares 565,140$6.83M1.17%+288,256Timeline
CLPTCLEARPOINT NEURO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 16,651 shares; 2025Q4: 481,858 shares 481,858$6.59M1.13%+465,207Timeline
ARQTARCUTIS BIOTHERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,778,318 shares; 2024Q4: 500,966 shares; 2025Q1: 440,073 shares; 2025Q2: 205,672 shares; 2025Q3: 411,893 shares; 2025Q4: 224,740 shares 224,740$6.53M1.12%-187,153Timeline
EYPTEYEPOINT INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 579,500 shares; 2025Q1: not reported; 2025Q2: 329,254 shares; 2025Q3: not reported; 2025Q4: 353,849 shares 353,849$6.46M1.11%newTimeline
IMTXIMMATICS N.VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 449,735 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 610,308 shares 610,308$6.41M1.1%newTimeline
OCULOCULAR THERAPEUTIX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 124,523 shares; 2025Q2: not reported; 2025Q3: 359,470 shares; 2025Q4: 522,693 shares 522,693$6.35M1.09%+163,223Timeline
RYTMRHYTHM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 41,268 shares; 2024Q4: 208,016 shares; 2025Q1: 33,816 shares; 2025Q2: 176,752 shares; 2025Q3: 91,444 shares; 2025Q4: 58,915 shares 58,915$6.31M1.08%-32,529Timeline
PRAXPRAXIS PRECISION MEDICINES IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 174,034 shares; 2024Q4: 134,178 shares; 2025Q1: not reported; 2025Q2: 32,255 shares; 2025Q3: not reported; 2025Q4: 21,067 shares 21,067$6.21M1.07%newTimeline
APGEAPOGEE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 84,466 shares; 2025Q3: not reported; 2025Q4: 80,574 shares 80,574$6.08M1.04%newTimeline
INCYINCYTE CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 129,490 shares; 2024Q4: 193,623 shares; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 43,754 shares; 2025Q4: 61,435 shares 61,435$6.07M1.04%+17,681Timeline
IDYAIDEAYA BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 132,703 shares; 2024Q4: not reported; 2025Q1: 66,999 shares; 2025Q2: 165,885 shares; 2025Q3: 371,825 shares; 2025Q4: 161,659 shares 161,659$5.59M0.96%-210,166Timeline
ASMBASSEMBLY BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 66,130 shares; 2025Q4: 156,728 shares 156,728$5.33M0.91%+90,598Timeline
MAZEMAZE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 125,877 shares 125,877$5.22M0.89%newTimeline
PTGXPROTAGONIST THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 141,714 shares; 2025Q1: 49,241 shares; 2025Q2: 16,770 shares; 2025Q3: 47,954 shares; 2025Q4: 59,430 shares 59,430$5.19M0.89%+11,476Timeline
LLYELI LILLY & COQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 4,759 shares 4,759$5.11M0.88%newTimeline
TRVITREVI THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 350,710 shares; 2025Q4: 399,557 shares 399,557$5M0.86%+48,847Timeline
RVMDREVOLUTION MEDICINES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 16,654 shares; 2024Q4: 193,535 shares; 2025Q1: 318,782 shares; 2025Q2: not reported; 2025Q3: 185,380 shares; 2025Q4: 62,032 shares 62,032$4.94M0.85%-123,348Timeline
VRDNVIRIDIAN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 154,320 shares 154,320$4.8M0.82%newTimeline
ABUSARBUTUS BIOPHARMA CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 467,882 shares; 2025Q2: not reported; 2025Q3: 205,388 shares; 2025Q4: 986,751 shares 986,751$4.75M0.81%+781,363Timeline
MLTXMOONLAKE IMMUNOTHERAPEUTICSQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 348,401 shares 348,401$4.59M0.79%newTimeline
CTMXCYTOMX THERAPEUTICS INC.Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,036,311 shares 1,036,311$4.41M0.76%newTimeline
XFORX4 PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 555,411 shares; 2025Q4: 898,465 shares 898,465$3.59M0.62%+343,054Timeline
WHWKWHITEHAWK THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 424,082 shares; 2025Q4: 1,458,807 shares 1,458,807$3.53M0.61%+1,034,725Timeline
DNTHDIANTHUS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 41,382 shares; 2025Q4: 79,284 shares 79,284$3.27M0.56%+37,902Timeline
ASNDASCENDIS PHARMA A/SQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 14,732 shares; 2025Q2: not reported; 2025Q3: 15,149 shares; 2025Q4: 14,842 shares 14,842$3.16M0.54%-307Timeline
RGENREPLIGEN CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 15,707 shares 15,707$2.57M0.44%newTimeline
NAMSNEWAMSTERDAM PHARMA COMPANYQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 104,585 shares; 2025Q2: 152,652 shares; 2025Q3: 150,573 shares; 2025Q4: 73,106 shares 73,106$2.56M0.44%-77,467Timeline
MBXMBX BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 50,000 shares; 2024Q4: not reported; 2025Q1: 96,615 shares; 2025Q2: 141,021 shares; 2025Q3: 75,000 shares; 2025Q4: 78,553 shares 78,553$2.48M0.43%+3,553Timeline
QNCXQUINCE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 739,264 shares 739,264$2.48M0.43%newTimeline
AVTXAVALO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 135,552 shares 135,552$2.46M0.42%newTimeline
IVVDINVIVYD INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 278,608 shares; 2025Q4: 989,822 shares 989,822$2.44M0.42%+711,214Timeline
MGTXMEIRAGTX HLDGS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 81,858 shares; 2025Q4: 287,689 shares 287,689$2.29M0.39%+205,831Timeline
IVAINVENTIVA SAQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 30,824 shares; 2025Q4: 467,242 shares 467,242$2.17M0.37%+436,418Timeline
ABBVABBVIE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 9,325 shares 9,325$2.13M0.37%newTimeline
ADCTADC THERAPEUTICS SAQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 283,286 shares; 2025Q3: 283,286 shares; 2025Q4: 502,570 shares 502,570$1.77M0.3%+219,284Timeline
MPLTMAPLIGHT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 100,000 shares 100,000$1.76M0.3%newTimeline
PHVSPHARVARIS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 58,389 shares 58,389$1.62M0.28%newTimeline
LEGNLEGEND BIOTECH CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 270,144 shares; 2025Q3: not reported; 2025Q4: 73,328 shares 73,328$1.59M0.27%newTimeline
BLTEBELITE BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 9,163 shares 9,163$1.47M0.25%newTimeline
XLOXilio Therapeutics Inc.Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 2,030,028 shares 2,030,028$1.3M0.22%newTimeline
EVMNEVOMMUNE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 68,196 shares 68,196$1.17M0.2%newTimeline
BBOTBRIDGEBIO ONCOLOGY THERAPEUTQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 186,614 shares; 2025Q4: 86,517 shares 86,517$1.08M0.19%-100,097Timeline
SYRESPYRE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 136,139 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 32,377 shares 32,377$1.06M0.18%newTimeline
QUREUNIQURE NVQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 90,000 shares; 2025Q1: 731,039 shares; 2025Q2: 572,615 shares; 2025Q3: 522,155 shares; 2025Q4: 43,485 shares 43,485$1.04M0.18%-478,670Timeline
TSHATAYSHA GENE THERAPIES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 1,203,941 shares; 2025Q3: 839,669 shares; 2025Q4: 182,130 shares 182,130$1M0.17%-657,539Timeline
GLUEMONTE ROSA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 61,577 shares 61,577$966K0.17%newTimeline
SABSSAB BIOTHERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 146,558 shares 146,558$548K0.09%newTimeline
VNDAVANDA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 58,989 shares 58,989$520K0.09%newTimeline
CAPRCAPRICOR THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 93,638 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 17,853 shares 17,853$515K0.09%newTimeline
KTTAPASITHEA THERAPEUTICS CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 355,082 shares 355,082$458K0.08%newTimeline
VTGNVISTAGEN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,846,792 shares; 2024Q4: 2,328,492 shares; 2025Q1: 2,366,554 shares; 2025Q2: 2,413,254 shares; 2025Q3: 2,488,685 shares; 2025Q4: 616,749 shares 616,749$142K0.02%-1,871,936Timeline

Options

Puts and calls, as filed. The amount and value describe the underlying shares, not the option premium, so they stay out of % of portfolio (H5).

SecurityTypeAmountValueChange
SRRKSCHOLAR ROCK HLDG CORP COMcall277,000$485K+258,600
CNTACENTESSA PHARMACEUTICALS PLC SPONSORED ADScall75,000$26.2K-97,500

Sold out in Q4 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
WVEWAVE LIFE SCIENCES LTD2,110,152$15.4Mshares
BHVNBIOHAVEN LTD1,017,311$15.3Mshares
CDTXCIDARA THERAPEUTICS INC152,325$14.6Mshares
ARGXARGENX SE12,465$9.19Mshares
RZLTREZOLUTE INC917,630$8.63Mshares
GHRSGH RESEARCH PLC545,275$7.8Mshares
ALKSALKERMES PLC241,637$7.25Mshares
BBIOBRIDGEBIO PHARMA INC127,435$6.62Mshares
INSMINSMED INC43,419$6.25Mshares
AKROAKERO THERAPEUTICS INC121,410$5.76Mshares
JAZZJAZZ PHARMACEUTICALS PLC39,072$5.15Mshares
RNAMAVIDITY BIOSCIENCES INC114,053$4.97Mshares
TECXTECTONIC THERAPEUTIC INC188,999$2.97Mshares
HROWHARROW INC57,619$2.78Mshares
EQEQUILLIUM INC1,908,935$2.73Mshares
UTHRUNITED THERAPEUTICS CORP DEL6,264$2.63Mshares
CGONCG ONCOLOGY INC63,019$2.54Mshares
QQQINVESCO QQQ TR3,797$2.28Mshares
TNGXTANGO THERAPEUTICS INC245,378$2.06Mshares
ORICORIC PHARMACEUTICALS INC166,461$2Mshares
PEPGPEPGEN INC389,189$1.8Mshares
FRNMPERCEPTIVE CAP SOLUTIONS COR150,000$1.59Mshares
TARAPROTARA THERAPEUTICS INC363,666$1.58Mshares
CMPSCOMPASS PATHWAYS PLC275,620$1.58Mshares
PYXSPYXIS ONCOLOGY INC689,538$1.53Mshares
BHVNBIOHAVEN LTD480,000$1.19Mcall
MIND MEDICINE MINDMED INCMIND MEDICINE MINDMED INC76,875$906Kshares
ENTAENANTA PHARMACEUTICALS INC75,194$900Kshares
ZBIOZENAS BIOPHARMA INC38,742$860Kshares
XBISPDR SERIES TRUST1,490,100$725Kput
CRVSCORVUS PHARMACEUTICALS INC96,439$711Kshares
KALVKALVISTA PHARMACEUTICALS INC56,770$691Kshares
ARCTARCTURUS THERAPEUTICS HLDGS35,606$656Kshares
VTYXVENTYX BIOSCIENCES INC167,470$521Kshares
ATAIBECKLEY INCATAIBECKLEY INC76,032$402Kshares
IONSIONIS PHARMACEUTICALS INC50,000$138Kcall
CRSPCRISPR THERAPEUTICS AG40,000$59Kcall
SNDXSYNDAX PHARMACEUTICALS INC100,000$55Kcall
IMVTIMMUNOVANT INC250,000$50Kcall
ARKGARK ETF TR200,000$30Kcall
AKROAKERO THERAPEUTICS INC15,500$9.69Kput
ABUSARBUTUS BIOPHARMA CORP95,000$9.5Kcall

How Q4 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001420506-26-000490 base2026-02-17acceptance time not in the bulk data set