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Disclosery

XENE XENON PHARMACEUTICALS INC

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Stock (common), issuer CIK 1582313

281 managers (291 13F filers) reported a position in XENE shares at 2026-03-31, 100,224,240 shares in all. 74 filers opened a position and 33 filers sold out during the quarter.

Managers
281
13F filers
291
New
74
Added
123
Reduced
60
Sold out
33
Shares held by filers
100,224,240

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2026

Filers in the available 13F reports with a share position at 2026-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC10,818,491$629M0.03%+1,898,24113F-HRTimelineGroup
Avoro Capital Advisors LLC5,777,777$336M3.31%+353,33313F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.5,640,118$328M0.01%+539,83413F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…4,829,641$281M0.05%+64,86213F-HRTimelineGroup
Driehaus Capital Management LLC4,491,653$261M1.92%-47,03813F-HRTimeline
Polar Capital Holdings Plcin group Polar Capital Holdings Plc4,405,312$256M1.12%+1,939,61813F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson4,175,982$243M0.12%+91,94813F-HR/ATimelineGroup
Capital International Investorsin group Capital International Investo…2,674,727$156M0.04%-740,23213F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC2,652,990$154M0.11%+1,331,77713F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO1,923,610$107M0.01%+429,57813F-HR/ATimelineGroup
STATE STREET CORPin group STATE STREET CORP1,720,533$100M<0.01%+227,98313F-HRTimelineGroup
Affinity Asset Advisors, LLC1,675,000$97.4M5.71%+425,00013F-HRTimeline
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…1,615,696$94M1.11%+1,073,67613F-HRTimelineGroup
Holocene Advisors, LP1,518,686$88.3M0.21%+236,60513F-HRTimeline
WESTFIELD CAPITAL MANAGEMENT CO LP1,401,483$81.5M0.34%+174,71213F-HRTimeline
Caligan Partners LP1,393,027$81M5.73%+843,36213F-HRTimeline
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …1,342,028$78M0.09%+281,80713F-HRTimelineGroup
BRAIDWELL LP1,338,452$77.8M2.6%-486,62413F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/1,329,591$77.3M0.01%+467,29113F-HRTimeline
JENNISON ASSOCIATES LLC1,318,814$76.7M0.05%+26,75913F-HRTimeline
Siren, L.L.C.in group Siren, L.L.C.1,318,564$76.7M2.13%+505,80313F-HRTimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.1,299,469$75.6M0.21%new13F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources1,280,577$74.5M0.02%+522,51813F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,092,932$63.5M<0.01%+140,25313F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.1,403,297$62.9M0.02%-190,51713F-HRTimeline
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC1,059,971$61.6M1.34%+612,77113F-HRTimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.972,237$56.5M0.09%+300,00013F-HRTimelineGroup
T. Rowe Price Investment Management, In…951,955$55.4M0.04%+404,34213F-HRTimeline
Capital World Investors840,072$48.9M0.01%+184,33513F-HRTimeline
Commodore Capital LPin group Commodore Capital LP825,000$48M2.78%-975,00013F-HRTimelineGroup
VANGUARD GROUP INCgroup of 7 filers holding787,830$45.8M+783,297Timeline
First Turn Management, LLC786,844$45.8M5.11%-12,89913F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC769,875$44.8M0.01%+73,82813F-HRTimelineGroup
Rock Springs Capital Management LP763,020$44.4M2.62%-24,76813F-HRTimeline
Fiera Capital Corpin group Fiera Capital Corp709,529$41.3M0.14%+23,47313F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC679,314$39.5M0.02%-1,15913F-HRTimelineGroup
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…679,709$39.2M0.04%+53,72413F-HRTimelineGroup
Vestal Point Capital, LP639,900$37.2M1.04%+39,90013F-HRTimeline
Aberdeen Group plcin group Aberdeen Group plc609,929$35.5M0.06%-140,36213F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP606,085$35.2M0.03%+169,34213F-HRTimelineGroup
MPM BIOIMPACT LLC588,706$34.2M2.64%+103,08613F-HRTimeline
LOOMIS SAYLES & CO L Pin group LOOMIS SAYLES & CO L P564,897$32.8M0.04%-47,13513F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP527,783$30.7M<0.01%+89,06913F-HRTimelineGroup
Parkman Healthcare Partners LLC497,035$28.9M3%+342,85113F-HRTimeline
TUDOR INVESTMENT CORP ET AL495,591$28.8M0.16%+241,58913F-HRTimeline
Octagon Capital Advisors LP490,000$28.5M3.15%new13F-HRTimeline
NOVO HOLDINGS A/S485,438$28.2M2.29%new13F-HRTimeline
Candriam S.C.A.476,494$27.7M0.14%+59,09213F-HRTimeline
UBS Group AGgroup of 2 filers holding474,790$27.6M+422,015Timeline
MORGAN STANLEYin group MORGAN STANLEY473,759$27.5M<0.01%+179,42713F-HRTimelineGroup
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…470,000$27.3M0.04%-215,10013F-HRTimelineGroup
Logos Global Management LP450,000$26.2M1.35%new13F-HRTimeline
Trails Edge Capital Partners, LP440,000$25.6M6.02%-157,09213F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp396,138$23M<0.01%+8,98013F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP370,208$21.5M0.12%013F-HRTimelineGroup
TimesSquare Capital Management, LLC359,293$20.9M0.35%-173,44713F-HRTimeline
Schonfeld Strategic Advisors LLC324,722$18.9M0.15%new13F-HRTimeline
Sofinnova Investments, Inc.305,216$17.7M0.89%+245,31613F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC300,500$17.5M0.03%new13F-HRTimeline
Soleus Capital Management, L.P.292,000$17M0.69%new13F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC270,412$15.7M0.36%+234,73113F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/265,267$15.4M<0.01%+43,89913F-HRTimelineGroup
ALGERT GLOBAL LLC264,200$15.4M0.23%+141,01113F-HR/ATimeline
Redmile Group, LLCin group Redmile Group, LLC262,674$15.3M1.01%+128,79213F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD254,483$14.8M0.03%+48,91413F-HRTimeline
DAFNA Capital Management LLC250,772$14.6M3.32%-37,16713F-HRTimeline
Nuveen, LLCin group TIAA250,036$14.5M<0.01%+33,79813F-HRTimelineGroup
NAN FUNG TRINITY (HK) LTD247,765$14.4M1.58%+20,80013F-HRTimeline
Nicholas Investment Partners, LP247,101$14.4M1.04%+4,11213F-HRTimeline
Allspring Global Investments Holdings, …in group Allspring Global Investments …246,306$14M0.02%new13F-HRTimelineGroup
Duquesne Family Office LLC238,600$13.9M0.47%new13F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC238,209$13.9M<0.01%-362,75513F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management233,905$13.6M0.03%+149,54513F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC228,899$13.3M0.8%+24,93013F-HRTimelineGroup
Patient Square Capital LP227,000$13.2M2.34%+90,50013F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC201,785$11.7M0.01%-433,27113F-HRTimelineGroup
Integral Health Asset Management, LLC200,000$11.6M0.62%new13F-HRTimeline
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…197,759$11.5M1.36%new13F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding195,605$11.4M+187,286Timeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co189,080$11M<0.01%+2113F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND188,505$11M0.02%+1,80013F-HRTimeline
NEXTBio Capital Management LP183,225$10.7M4.95%-47913F-HRTimeline
DNB Asset Management ASin group DNB Asset Management AS181,085$10.5M0.04%-91,74613F-HRTimelineGroup
ExodusPoint Capital Management, LP173,425$10.1M0.1%new13F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\162,682$9.46M<0.01%-27,55113F-HRTimelineGroup
Foresite Capital Management IV, LLCin group Foresite Capital Management V…160,000$9.3M3.92%013F-HRTimelineGroup
Swiss National Bank157,700$9.17M0.01%+43,70013F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC155,776$9.06M0.13%+124,78913F-HRTimelineGroup
Woodline Partners LP150,302$8.74M0.03%new13F-HR/ATimeline
PEREGRINE CAPITAL MANAGEMENT LLC143,136$8.32M0.31%-31,71513F-HRTimeline
STEMPOINT CAPITAL LP140,755$8.18M1.57%-207,85013F-HR/ATimeline
NEUBERGER BERMAN GROUP LLCin group NEUBERGER BERMAN GROUP LLC130,438$7.58M0.01%-48,30913F-HRTimelineGroup
Eversept Partners, LP129,574$7.53M0.5%-101,80613F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…129,399$7.52M0.01%+43,17913F-HRTimelineGroup
KBC Group NVin group KBC Group NV129,010$7.5M0.02%+126,23013F-HRTimelineGroup
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.127,000$7.39M1.27%new13F-HRTimelineGroup
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC121,558$7.07M<0.01%new13F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN115,652$6.73M<0.01%-36,64513F-HR/ATimelineGroup
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…115,594$6.72M0.08%-49413F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO114,381$6.65M0.01%+70,52313F-HRTimelineGroup
Granahan Investment Management, LLC104,478$6.08M0.29%+11,70013F-HRTimeline
RHUMBLINE ADVISERS101,785$5.92M0.01%+11,64213F-HRTimeline
Burkehill Global Management, LP100,000$5.82M0.29%new13F-HRTimeline
AXIOM INVESTORS LLC /DE99,568$5.79M0.06%new13F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…92,747$5.39M0.01%+36,18313F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA90,387$5.25M<0.01%+63013F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC88,598$5.15M<0.01%+5,34313F-HRTimelineGroup
Y-Intercept (Hong Kong) Ltd85,388$4.97M0.09%+12,43113F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS80,392$4.67M<0.01%-13,07013F-HRTimelineGroup
Aquatic Capital Management LLC79,199$4.61M0.13%new13F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC78,905$4.59M<0.01%-30,63913F-HR/ATimelineGroup
SCHRODER INVESTMENT MANAGEMENT GROUP81,156$4.51M<0.01%013F-HRTimeline
SEVEN GRAND MANAGERS, LLC75,000$4.36M0.29%new13F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc73,489$4.27M<0.01%+3,22413F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC68,363$3.98M<0.01%+7,50513F-HRTimelineGroup
ALPS ADVISORS INCin group ALPS ADVISORS INC67,723$3.94M0.02%+4,42113F-HRTimelineGroup
Trexquant Investment LP67,361$3.92M0.03%new13F-HRTimeline
Informed Momentum Co LLC66,550$3.87M0.45%new13F-HRTimeline
Artia Global Partners LP65,000$3.78M0.85%+25,00013F-HRTimeline
CASTLEARK MANAGEMENT LLC64,563$3.75M0.12%new13F-HRTimeline
Atika Capital Management LLCin group Atika Capital Management LLC59,900$3.48M0.55%-32,60613F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.59,103$3.44M<0.01%+8,15613F-HRTimelineGroup
LMR Partners LLPin group LMR Partners LLP56,200$3.27M0.03%new13F-HRTimelineGroup
Quantinno Capital Management LP55,444$3.22M0.01%+30,81613F-HRTimeline
Verition Fund Management LLC55,000$3.2M0.03%-38,75613F-HRTimeline
Palo Alto Investors LP51,345$2.99M0.46%-45,17413F-HRTimeline
LAZARD ASSET MANAGEMENT LLCin group LAZARD ASSET MANAGEMENT LLC50,755$2.95M<0.01%-27,90813F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC49,970$2.91M<0.01%new13F-HRTimeline
HighVista Strategies LLC49,050$2.85M0.79%new13F-HRTimeline
Erste Asset Management GmbHin group Erste Asset Management GmbH50,000$2.78M0.03%013F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…47,343$2.75M0.01%+5,31813F-HRTimelineGroup
NOMURA ASSET MANAGEMENT CO LTDgroup of 2 filers holding47,041$2.73M-916Timeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding44,852$2.61M+5,787Timeline
Qube Research & Technologies Ltd44,044$2.56M<0.01%new13F-HRTimeline
DekaBank Deutsche Girozentrale39,000$2.2M<0.01%013F-HRTimeline
Legato Capital Management LLC36,641$2.13M0.19%-39713F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC36,068$2.1M<0.01%+26713F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…35,204$2.05M<0.01%+9,61513F-HRTimeline
ACT CAPITAL MANAGEMENT, LLC33,500$1.95M1.53%new13F-HRTimeline
TLS Advisors LLC30,956$1.8M4.27%+12,09813F-HRTimeline
Calamos Advisors LLCin group Calamos Advisors LLC30,374$1.77M0.01%new13F-HRTimelineGroup
Creative Planningin group Creative Planning29,818$1.73M<0.01%+10,61813F-HRTimelineGroup
Handelsbanken Fonder AB29,800$1.73M0.01%013F-HRTimeline
Corient Private Wealth LPin group Corient Private Wealth LP28,302$1.65M<0.01%new13F-HRTimelineGroup
Rhenman & Partners Asset Management AB28,000$1.63M0.2%-111,00013F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd28,000$1.63M0.03%+6,50213F-HRTimelineGroup
TD Asset Management Inc27,074$1.57M<0.01%-11,07413F-HRTimeline
Swedbank ABin group Swedbank AB26,200$1.52M<0.01%new13F-HRTimelineGroup
SummitTX Capital, L.P.26,186$1.52M0.05%new13F-HRTimeline
BAMCO INC /NY/in group Baron Capital25,000$1.45M<0.01%-5,00013F-HRTimelineGroup
Vestmark Advisory Solutions, Inc.24,025$1.4M0.02%+2,14113F-HRTimeline
Rathbones Group PLC23,666$1.38M0.01%013F-HR/ATimeline
Police & Firemen's Retirement System of…23,405$1.36M0.01%+3,27713F-HRTimeline
HighMark Wealth Management LLC23,000$1.34M0.54%013F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM21,869$1.27M0.01%+5,69013F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …21,684$1.26M<0.01%-10,93813F-HRTimelineGroup
SANDERS MORRIS HARRIS LLC21,500$1.25M0.2%new13F-HRTimeline
TEACHERS RETIREMENT SYSTEM OF THE STATE…21,133$1.23M0.01%new13F-HRTimeline
Birchview Capital, LP21,000$1.22M0.7%013F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC20,272$1.18M<0.01%-99713F-HRTimelineGroup
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…19,807$1.15M<0.01%+6913F-HRTimelineGroup
Connor, Clark & Lunn Investment Managem…19,439$1.13M<0.01%new13F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…19,097$1.11M<0.01%new13F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC19,062$1.11M0.01%-6,77813F-HRTimeline
CIBC WORLD MARKET INC.18,960$1.1M<0.01%+5,50013F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.18,940$1.1M<0.01%-11,91113F-HRTimelineGroup
MARTINGALE ASSET MANAGEMENT L P18,806$1.09M0.03%new13F-HRTimeline
Campbell & CO Investment Adviser LLC18,156$1.06M0.06%+2,05113F-HRTimeline
Amundiin group Amundi18,013$1.05M<0.01%+13,40413F-HRTimelineGroup
KLP KAPITALFORVALTNING AS17,600$1.02M<0.01%+5,30013F-HRTimeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP16,718$972K<0.01%-83013F-HRTimelineGroup
ProShare Advisors LLC16,250$945K<0.01%-1,02913F-HRTimeline
China Universal Asset Management Co., L…14,763$858K0.06%+2,17113F-HRTimeline
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…14,072$818K<0.01%new13F-HRTimelineGroup
Orion Porfolio Solutions, LLC13,817$803K0.01%-59013F-HRTimeline
SBI Okasan Asset Management Co.Ltd.14,400$800K0.03%013F-HRTimeline
Neo Ivy Capital Management13,710$797K0.21%+6,23313F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC13,010$757K<0.01%new13F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC12,151$707K<0.01%+4,79013F-HRTimelineGroup
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…12,041$700K0.01%new13F-HRTimelineGroup
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…10,633$618K<0.01%013F-HRTimeline
Covalis Capital LLPin group Covalis Capital LLP10,000$582K0.04%new13F-HRTimelineGroup
Elmwood Wealth Management, Inc.9,807$570K0.16%-95013F-HRTimeline
Engineers Gate Manager LP9,326$542K0.01%new13F-HRTimeline
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP9,133$531K<0.01%+2,77213F-HRTimelineGroup
Thrivent Financial for Lutheransin group Thrivent Financial for Luther…9,122$531K<0.01%+3,53913F-HRTimelineGroup
SG Americas Securities, LLC9,119$530K<0.01%+2,04213F-HRTimeline
J. Safra Sarasin Holding AGin group J. Safra Sarasin Holding AG9,071$527K0.01%-4,51013F-HRTimelineGroup
EntryPoint Capital, LLC8,832$514K0.15%+3,80413F-HRTimeline
XPONANCE LLC8,465$492K<0.01%+2,49013F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…8,097$471K<0.01%+1,52313F-HRTimelineGroup
Allianz Asset Management GmbHin group Allianz SE7,600$442K<0.01%-1,80013F-HRTimelineGroup
TEACHER RETIREMENT SYSTEM OF TEXAS7,599$442K<0.01%-1,03313F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC7,279$423K<0.01%new13F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…7,138$415K0.01%+97013F-HRTimelineGroup
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co7,024$411K<0.01%013F-HRTimelineGroup
Advisors Asset Management, Inc.6,961$405K0.01%-1,05113F-HRTimeline
OXFORD ASSET MANAGEMENT LLP6,884$400K0.16%-49513F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
PenderFund Capital Management Ltd.6,850$398K0.06%013F-HRTimeline
Bridgefront Capital, LLC6,564$382K0.09%new13F-HRTimeline