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Disclosery

XENE XENON PHARMACEUTICALS INC

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Stock (common), issuer CIK 1582313

205 managers (208 13F filers) reported a position in XENE shares at 2025-06-30, 83,131,105 shares in all. 42 filers opened a position and 40 filers sold out during the quarter.

Managers
205
13F filers
208
New
42
Added
77
Reduced
55
Sold out
40
Shares held by filers
83,131,105

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2025

Filers in the available 13F reports with a share position at 2025-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC8,884,363$278M0.02%+596,86413F-HRTimelineGroup
Avoro Capital Advisors LLC5,400,000$169M2.96%-341,66613F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.5,365,327$168M<0.01%+3,329,20213F-HRTimelineGroup
Driehaus Capital Management LLC4,335,648$136M1.09%-249,21113F-HRTimeline
BRAIDWELL LP3,605,029$113M3.86%+895,15413F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson3,577,735$112M0.05%+252,64213F-HRTimelineGroup
Capital International Investorsin group Capital International Investo…3,181,549$99.6M0.02%+92,81913F-HRTimelineGroup
Commodore Capital LPin group Commodore Capital LP3,025,000$94.7M6.68%+700,00013F-HRTimelineGroup
Polar Capital Holdings Plcin group Polar Capital Holdings Plc2,703,256$84.6M0.44%+80,21713F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…2,174,761$68.1M0.01%-1,614,43613F-HRTimelineGroup
Vestal Point Capital, LP2,000,000$62.6M3.3%+700,00013F-HRTimeline
Holocene Advisors, LP1,809,475$56.6M0.14%new13F-HRTimeline
ALLIANCEBERNSTEIN L.P.1,518,527$47.5M0.02%+189,14113F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…1,474,449$46.2M0.05%-3,16813F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP1,380,460$43.2M<0.01%+1,074,84013F-HRTimelineGroup
Deep Track Capital, LP1,350,000$42.3M1.36%+350,00013F-HRTimeline
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…1,290,100$40.4M0.07%-624,64913F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO1,256,581$39.3M<0.01%-101,02113F-HRTimelineGroup
WESTFIELD CAPITAL MANAGEMENT CO LP1,152,605$36.1M0.15%-238,76513F-HRTimeline
Affinity Asset Advisors, LLC1,100,000$34.4M5.09%-228,17513F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP1,020,254$31.9M0.04%+262,10913F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC970,343$30.4M<0.01%+900,74613F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC947,877$29.7M0.75%013F-HRTimelineGroup
Rock Springs Capital Management LP931,681$29.2M1.82%013F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC882,835$27.6M0.02%+648,77913F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC873,228$27.3M<0.01%+536,71413F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.812,761$25.4M1.32%+80,00013F-HRTimelineGroup
JENNISON ASSOCIATES LLC696,383$21.8M0.01%-80,31013F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC679,857$21.3M0.01%new13F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources666,466$20.9M0.01%+175,34613F-HRTimelineGroup
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …661,082$20.7M0.05%-42,71313F-HRTimelineGroup
First Turn Management, LLC660,617$20.7M3.86%-22,83413F-HRTimeline
LOOMIS SAYLES & CO L Pin group LOOMIS SAYLES & CO L P657,165$20.6M0.03%-15,84613F-HRTimelineGroup
Capital World Investors655,737$20.5M<0.01%-1,568,97813F-HRTimeline
TimesSquare Capital Management, LLC571,242$17.9M0.26%-174,30913F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC561,800$17.6M<0.01%+119,06813F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding557,442$17.4M+388,541Timeline
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…542,020$17M0.31%new13F-HRTimelineGroup
Fiera Capital Corpin group Fiera Capital Corp530,683$16.6M0.06%+1,24113F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc521,492$16.3M0.03%+117,33813F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP489,940$15.3M<0.01%+408,91613F-HRTimelineGroup
Saturn V Capital Management LP468,364$14.7M5.94%+54,65313F-HRTimeline
Assenagon Asset Management S.A.436,974$13.7M0.02%+195,76813F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp436,020$13.6M<0.01%+184,87313F-HRTimelineGroup
Candriam S.C.A.396,636$12.4M0.07%-58,01413F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY387,596$12.1M<0.01%+258,10513F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP379,988$11.9M<0.01%+165,12813F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP370,208$11.6M0.11%+22,80013F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/358,432$11.2M<0.01%+221,86313F-HRTimelineGroup
MPM BIOIMPACT LLC323,398$10.1M1.75%+20,00013F-HRTimeline
Foresite Capital Management VI LLCgroup of 2 filers holding320,000$10MnewTimeline
DAFNA Capital Management LLC287,939$9.01M2.49%+14,20013F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC259,503$8.12M1.32%+131,95513F-HRTimelineGroup
Granahan Investment Management, LLC240,038$7.51M0.31%+56,23013F-HRTimeline
DNB Asset Management ASin group DNB Asset Management AS234,157$7.33M0.03%+4,67513F-HRTimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.232,500$7.28M0.01%013F-HRTimelineGroup
Nuveen, LLCin group TIAA228,567$7.15M<0.01%new13F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…222,352$6.96M0.01%new13F-HRTimelineGroup
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC200,791$6.28M0.24%-124,53313F-HRTimelineGroup
GREAT POINT PARTNERS LLC200,000$6.26M4.07%-45,27213F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co192,242$6.02M<0.01%new13F-HRTimelineGroup
First Light Asset Management, LLC188,367$5.9M0.76%-439,53713F-HRTimeline
AXA S.A.in group AXA S.A.175,632$5.5M0.02%+28213F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD174,850$5.47M0.01%+77,70113F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND166,472$5.21M0.01%+24,10013F-HR/ATimeline
NAN FUNG TRINITY (HK) LTD158,605$4.96M0.59%new13F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC152,770$4.78M<0.01%+133,50013F-HR/ATimelineGroup
Parkman Healthcare Partners LLC150,373$4.71M0.54%-24,20313F-HRTimeline
NEUBERGER BERMAN GROUP LLCin group NEUBERGER BERMAN GROUP LLC147,411$4.61M<0.01%+102,55913F-HR/ATimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA147,226$4.61M<0.01%+87,86013F-HR/ATimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.141,783$4.44M<0.01%-10,40513F-HRTimelineGroup
SCHRODER INVESTMENT MANAGEMENT GROUP129,103$4.04M<0.01%-8,11813F-HRTimeline
Swiss National Bank124,300$3.89M<0.01%-1,30013F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC122,026$3.82M<0.01%+18,40213F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC120,045$3.76M<0.01%-567,04313F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN112,562$3.52M<0.01%+46,65013F-HRTimelineGroup
RHUMBLINE ADVISERS109,700$3.43M<0.01%+109,67113F-HRTimeline
Avidity Partners Management LP107,891$3.38M0.68%-121,10913F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\104,534$3.27M<0.01%+50,82313F-HRTimelineGroup
ALGERT GLOBAL LLC102,345$3.2M0.07%-21,07013F-HR/ATimeline
Caption Management, LLC100,940$3.16M0.29%new13F-HRTimeline
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…95,568$2.99M0.03%+46,80513F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding95,300$2.98M-440,483Timeline
MOORE CAPITAL MANAGEMENT, LP90,000$2.82M0.06%+35,00013F-HRTimeline
J. Safra Sarasin Holding AGin group J. Safra Sarasin Holding AG82,048$2.57M0.04%+51,47513F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc81,792$2.56M<0.01%+21,38613F-HRTimelineGroup
Soleus Capital Management, L.P.78,800$2.47M0.17%new13F-HRTimeline
T. Rowe Price Investment Management, In…76,943$2.41M<0.01%-720,04313F-HRTimeline
Nicholas Investment Partners, LP68,896$2.16M0.19%-18,07213F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management68,869$2.16M<0.01%-198,27313F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC65,214$2.04M<0.01%+1,82913F-HRTimelineGroup
Man Group plcin group Man Group plc62,348$1.95M<0.01%new13F-HRTimelineGroup
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…61,772$1.93M0.01%+11,35513F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…60,233$1.89M<0.01%+4,74113F-HRTimeline
Nebula Research & Development LLC60,223$1.88M0.16%+13,66213F-HRTimeline
Invesco Ltd.in group Invesco Ltd.59,598$1.87M<0.01%-146,16513F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC59,465$1.86M<0.01%+11,40013F-HRTimelineGroup
BAMCO INC /NY/in group Baron Capital56,000$1.75M<0.01%-44,10013F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…52,136$1.63M<0.01%-23,20513F-HRTimelineGroup
Erste Asset Management GmbHin group Erste Asset Management GmbH50,000$1.62M0.01%013F-HRTimelineGroup
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC47,755$1.53M<0.01%+8,75513F-HRTimelineGroup
Skandinaviska Enskilda Banken AB (publ)47,457$1.49M0.01%013F-HRTimeline
HighVista Strategies LLC45,620$1.43M0.52%-21,16813F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…45,547$1.43M0.01%new13F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding44,612$1.4M+42,051Timeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC43,676$1.37M<0.01%new13F-HRTimelineGroup
Woodline Partners LP43,380$1.36M0.01%new13F-HRTimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC41,380$1.3M0.01%-13,95213F-HRTimelineGroup
DekaBank Deutsche Girozentrale39,000$1.26M<0.01%013F-HRTimeline
Artia Global Partners LP40,000$1.25M0.32%013F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC39,403$1.23M<0.01%-3,44713F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/37,935$1.19M<0.01%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC36,290$1.14M<0.01%+29,26113F-HRTimelineGroup
Rhenman & Partners Asset Management AB35,000$1.1M0.14%013F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC34,312$1.07M0.01%new13F-HRTimeline
TLS Advisors LLC32,956$1.03M3.22%013F-HRTimeline
HARBOR CAPITAL ADVISORS, INC.30,036$940K0.04%-26,55513F-HRTimeline
HighMark Wealth Management LLC26,100$817K0.4%+20,00013F-HRTimeline
Ensign Peak Advisors, Inc26,094$817K<0.01%013F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …26,079$816K<0.01%new13F-HRTimelineGroup
Polar Asset Management Partners Inc.25,300$792K0.02%new13F-HRTimeline
NJ State Employees Deferred Compensatio…25,000$782K0.09%013F-HRTimeline
READYSTATE ASSET MANAGEMENT LP24,814$777K0.03%new13F-HRTimeline
CenterBook Partners LP24,664$772K0.04%+2,45313F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…23,866$747K<0.01%+4,91013F-HRTimeline
Rathbones Group PLC23,666$741K<0.01%013F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO22,723$711K<0.01%+13,31913F-HRTimelineGroup
Handelsbanken Fonder AB22,700$711K<0.01%013F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC21,250$665K<0.01%+1,31613F-HRTimelineGroup
OXFORD ASSET MANAGEMENT LLP21,138$662K0.22%+14,96413F-HRTimeline
Birchview Capital, LP21,000$657K0.65%013F-HRTimeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP20,622$645K<0.01%+9513F-HRTimelineGroup
SG Americas Securities, LLC19,177$600K<0.01%+10,52213F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM18,956$593K<0.01%+37713F-HRTimeline
ProShare Advisors LLC18,448$577K<0.01%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS17,844$559K<0.01%+14,63413F-HRTimelineGroup
TEACHER RETIREMENT SYSTEM OF TEXAS17,534$549K<0.01%+9513F-HRTimeline
NATIXIS ADVISORS, LLCin group Natixis Investment Managers17,424$545K<0.01%-6,58613F-HRTimelineGroup
Police & Firemen's Retirement System of…17,358$543K0.01%new13F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC16,991$532K0.01%new13F-HR/ATimelineGroup
CIBC WORLD MARKET INC.16,335$511K<0.01%013F-HRTimeline
China Universal Asset Management Co., L…15,412$482K0.05%+5913F-HRTimeline
PEAK6 LLCin group PEAK6 LLC15,000$470K0.02%new13F-HR/ATimelineGroup
Orion Porfolio Solutions, LLC14,916$467K<0.01%-61513F-HR/ATimeline
KLP KAPITALFORVALTNING AS12,800$401K<0.01%013F-HRTimeline
Advisors Asset Management, Inc.12,205$382K0.01%-2,07613F-HR/ATimeline
Supplemental Annuity Collective Trust o…11,000$344K0.1%013F-HRTimeline
Knott David M Jr10,962$343K0.16%-4,90413F-HRTimeline
Elmwood Wealth Management, Inc.10,824$339K0.13%-18313F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…10,633$333K<0.01%013F-HRTimeline
Schonfeld Strategic Advisors LLC10,538$330K<0.01%-12,41613F-HRTimeline
Legato Capital Management LLC9,622$301K0.04%013F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE9,400$294K<0.01%013F-HRTimelineGroup
CIBC WORLD MARKETS CORP9,363$293K<0.01%new13F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC8,600$269K<0.01%-146,10013F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…7,758$243K0.01%new13F-HRTimelineGroup
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co7,024$220K<0.01%013F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…5,357$168K<0.01%+5,30713F-HRTimelineGroup
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…5,000$156K<0.01%013F-HRTimelineGroup
GROUP ONE TRADING LLC4,653$146K<0.01%new13F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…3,462$108K<0.01%-1,75813F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…2,867$89.7K0.03%-1,29413F-HRTimelineGroup
AMALGAMATED BANK2,595$81K<0.01%new13F-HRTimeline
Quarry LP2,000$62.6K0.01%013F-HRTimeline
IFP Advisors, Inc1,865$61.5K<0.01%-5613F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,952$61.1K<0.01%013F-HRTimeline
KBC Group NVin group KBC Group NV1,871$59K<0.01%-89013F-HRTimelineGroup
L1 Capital Pty Ltd1,296$40.6K<0.01%new13F-HR/ATimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.1,225$40.2K<0.01%+1,03413F-HR/ATimelineGroup
ELEVATION POINT WEALTH PARTNERS, LLC1,015$31.8K<0.01%new13F-HR/ATimeline
DANSKE BANK A/S800$25K<0.01%new13F-HRTimeline
Farther Finance Advisors, LLC784$24.5K<0.01%new13F-HRTimeline
NISA INVESTMENT ADVISORS, LLC689$21.6K<0.01%new13F-HRTimeline
SIGNATUREFD, LLC661$20.7K<0.01%+47613F-HRTimeline
State of Wyoming541$16.9K<0.01%-3313F-HRTimeline
Clearstead Advisors, LLC347$10.9K<0.01%+12913F-HRTimeline
First Horizon Advisors, Inc.345$10.8K<0.01%-2513F-HRTimeline
Mitsubishi UFJ Asset Management Co., Lt…in group Mitsubishi UFJ Trust & Bankin…276$8.64K<0.01%013F-HRTimelineGroup
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.252$8K<0.01%013F-HRTimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/235$7.35K<0.01%013F-HR/ATimelineGroup
CWM, LLCin group CWM, LLC237$7K<0.01%-213F-HRTimelineGroup
Spire Wealth Managementin group Spire Wealth Management200$6.26K<0.01%013F-HRTimelineGroup
United Community Bankin group United Community Bank200$6.26K<0.01%new13F-HRTimelineGroup
Sterling Capital Management LLC184$5.76K<0.01%new13F-HR/ATimeline
US BANCORP \DE\in group US BANCORP \DE\181$5.67K<0.01%-9413F-HRTimelineGroup
Parallel Advisors, LLC135$4.23K<0.01%-55313F-HRTimeline
ROTHSCHILD INVESTMENT LLC130$4.07K<0.01%new13F-HRTimeline
Caitong International Asset Management …104$3.25K<0.01%-80113F-HRTimeline
Brooklyn Investment Group103$3.22K<0.01%new13F-HR/ATimeline
J.Safra Asset Management Corp87$2.72K<0.01%+313F-HR/ATimeline
PRINCIPAL SECURITIES, INC.in group PRINCIPAL FINANCIAL GROUP INC68$2.13K<0.01%+1013F-HRTimelineGroup
Cape Investment Advisory, Inc.39$1.22K<0.01%new13F-HRTimeline
WHITTIER TRUST CO OF NEVADA INC36$1.13K<0.01%013F-HRTimeline
Allworth Financial LP35$1.1K<0.01%+2313F-HRTimeline
CVA Family Office, LLC33$1.03K<0.01%013F-HRTimeline
Parkside Financial Bank & Trust30$939<0.01%new13F-HRTimeline
Blue Trust, Inc.28$876<0.01%-24213F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…26$814<0.01%-3213F-HRTimelineGroup
Park Place Capital Corp16$513<0.01%013F-HRTimeline
GAMMA Investing LLC14$438<0.01%+613F-HRTimeline