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Disclosery

XENE XENON PHARMACEUTICALS INC

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Stock (common), issuer CIK 1582313

218 managers (220 13F filers) reported a position in XENE shares at 2025-09-30, 84,320,830 shares in all. 33 filers opened a position and 20 filers sold out during the quarter.

Managers
218
13F filers
220
New
33
Added
68
Reduced
71
Sold out
20
Shares held by filers
84,320,830

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC8,918,907$358M0.02%+34,54413F-HRTimelineGroup
Avoro Capital Advisors LLC5,400,000$217M2.8%013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.4,770,951$192M<0.01%-594,37613F-HRTimelineGroup
Driehaus Capital Management LLC4,169,114$167M1.2%-166,53413F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson3,943,885$158M0.07%+366,15013F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…3,609,857$145M0.03%+1,435,09613F-HRTimelineGroup
BRAIDWELL LP3,605,029$145M4.29%013F-HRTimeline
Capital International Investorsin group Capital International Investo…3,181,493$128M0.02%-5613F-HRTimelineGroup
Commodore Capital LPin group Commodore Capital LP2,700,000$108M5.29%-325,00013F-HRTimelineGroup
Polar Capital Holdings Plcin group Polar Capital Holdings Plc2,546,766$102M0.49%-156,49013F-HRTimelineGroup
Holocene Advisors, LP1,976,553$79.4M0.18%+167,07813F-HRTimeline
ALLIANCEBERNSTEIN L.P.1,654,417$66.4M0.02%+135,89013F-HRTimeline
STATE STREET CORPin group STATE STREET CORP1,466,467$58.9M<0.01%+86,00713F-HRTimelineGroup
Affinity Asset Advisors, LLC1,400,000$56.2M5.23%+300,00013F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO1,399,033$56.2M<0.01%+142,45213F-HR/ATimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC1,384,007$55.6M0.04%+501,17213F-HRTimelineGroup
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…1,262,579$50.6M0.05%-211,87013F-HRTimelineGroup
WESTFIELD CAPITAL MANAGEMENT CO LP1,206,066$48.4M0.2%+53,46113F-HRTimeline
Deep Track Capital, LP1,200,000$48.2M1.34%-150,00013F-HRTimeline
JENNISON ASSOCIATES LLC1,135,235$45.6M0.03%+438,85213F-HRTimeline
Vestal Point Capital, LP1,100,000$44.2M2%-900,00013F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC977,435$39.2M<0.01%+7,09213F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC959,098$38.5M0.03%+839,05313F-HRTimelineGroup
Rock Springs Capital Management LP851,744$34.2M2%-79,93713F-HRTimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC851,386$34.2M<0.01%-21,84213F-HRTimelineGroup
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…835,100$33.5M0.05%-455,00013F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.812,761$32.6M1.28%013F-HRTimelineGroup
First Turn Management, LLC799,743$32.1M4.82%+139,12613F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC720,659$28.9M<0.01%+158,85913F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources695,900$27.9M0.01%+29,43413F-HRTimelineGroup
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …670,257$26.9M0.07%+9,17513F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC659,257$26.5M0.01%-20,60013F-HRTimelineGroup
Capital World Investors655,737$26.3M<0.01%013F-HRTimeline
LOOMIS SAYLES & CO L Pin group LOOMIS SAYLES & CO L P640,626$25.7M0.03%-16,53913F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP611,982$24.6M0.03%-408,27213F-HRTimelineGroup
T. Rowe Price Investment Management, In…599,113$24.1M0.01%+522,17013F-HRTimeline
Aberdeen Group plcin group Aberdeen Group plc579,145$23.3M0.04%+57,65313F-HRTimelineGroup
TimesSquare Capital Management, LLC556,800$22.4M0.32%-14,44213F-HRTimeline
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…542,020$21.8M0.33%013F-HRTimelineGroup
Fiera Capital Corpin group Fiera Capital Corp519,999$20.9M0.07%-10,68413F-HRTimelineGroup
Saturn V Capital Management LP503,701$20.2M4.44%+35,33713F-HRTimeline
MPM BIOIMPACT LLC503,398$20.2M3.31%+180,00013F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP498,147$20M<0.01%+8,20713F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP454,023$18.2M<0.01%+74,03513F-HRTimelineGroup
Caligan Partners LP444,565$17.8M2.48%new13F-HRTimeline
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC419,600$16.8M0.4%-528,27713F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp418,416$16.8M<0.01%-17,60413F-HRTimelineGroup
Candriam S.C.A.396,636$15.9M0.08%013F-HRTimeline
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP370,208$14.9M0.11%013F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY366,572$14.7M<0.01%-21,02413F-HR/ATimelineGroup
Tri Locum Partners LP366,102$14.7M3.38%new13F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management322,456$12.9M0.03%+253,58713F-HRTimelineGroup
DAFNA Capital Management LLC287,939$11.6M2.86%013F-HRTimeline
Jain Global LLC252,379$10.1M0.13%new13F-HRTimeline
DNB Asset Management ASin group DNB Asset Management AS249,081$10M0.04%+14,92413F-HRTimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.232,500$9.33M0.02%013F-HRTimelineGroup
Nuveen, LLCin group TIAA224,289$9.01M<0.01%-4,27813F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD208,372$8.37M0.02%+33,52213F-HRTimeline
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC200,791$8.06M0.23%013F-HRTimelineGroup
GREAT POINT PARTNERS LLC200,000$8.03M3.35%013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/199,106$7.99M<0.01%-159,32613F-HR/ATimelineGroup
STEMPOINT CAPITAL LP192,295$7.72M1.56%new13F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC189,098$7.59M0.75%-70,40513F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co188,747$7.58M<0.01%-3,49513F-HRTimelineGroup
AXA Investment Managers S.A.176,157$7.07M0.02%13F-HRTimeline
Parkman Healthcare Partners LLC176,137$7.07M0.78%+25,76413F-HRTimeline
NEUBERGER BERMAN GROUP LLCin group NEUBERGER BERMAN GROUP LLC172,354$6.92M0.01%+24,94313F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND171,708$6.89M0.01%+5,23613F-HRTimeline
Foresite Capital Management VI LLCgroup of 2 filers holding160,000$6.42M-160,000Timeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS159,238$6.39M<0.01%+141,39413F-HRTimelineGroup
NAN FUNG TRINITY (HK) LTD158,605$6.37M0.64%013F-HRTimeline
MOORE CAPITAL MANAGEMENT, LP140,000$5.62M0.11%+50,00013F-HRTimeline
Swiss National Bank126,400$5.07M<0.01%+2,10013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA120,545$4.84M<0.01%-26,68113F-HRTimelineGroup
Nicholas Investment Partners, LP119,098$4.78M0.37%+50,20213F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN115,221$4.63M<0.01%+2,65913F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\112,951$4.53M<0.01%+8,41713F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC111,300$4.47M<0.01%-41,47013F-HR/ATimelineGroup
RHUMBLINE ADVISERS106,791$4.29M<0.01%-2,90913F-HRTimeline
UBS Group AGgroup of 2 filers holding106,744$4.29M-450,698Timeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC97,567$3.92M<0.01%-24,45913F-HRTimelineGroup
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…94,935$3.81M0.04%-63313F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC89,879$3.61M<0.01%+46,20313F-HRTimelineGroup
Granahan Investment Management, LLC87,470$3.51M0.14%-152,56813F-HRTimeline
HighVista Strategies LLC82,190$3.3M0.81%+36,57013F-HRTimeline
Rhenman & Partners Asset Management AB81,000$3.25M0.36%+46,00013F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc79,848$3.21M<0.01%-1,94413F-HRTimelineGroup
SCHRODER INVESTMENT MANAGEMENT GROUP81,156$3.17M<0.01%-47,94713F-HRTimeline
TUDOR INVESTMENT CORP ET AL76,824$3.08M0.02%new13F-HR/ATimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC69,922$2.81M<0.01%+4,70813F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…69,892$2.81M<0.01%+17,75613F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC60,858$2.44M<0.01%+1,39313F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…60,237$2.42M<0.01%+413F-HRTimeline
Verition Fund Management LLC57,117$2.29M0.01%new13F-HRTimeline
Invesco Ltd.in group Invesco Ltd.56,064$2.25M<0.01%-3,53413F-HRTimelineGroup
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…55,711$2.24M0.01%-6,06113F-HRTimelineGroup
ALGERT GLOBAL LLC54,255$2.18M0.04%-48,09013F-HR/ATimeline
Avidity Partners Management LP53,400$2.14M0.49%-54,49113F-HRTimeline
Neo Ivy Capital Management49,838$2M0.49%new13F-HRTimeline
Erste Asset Management GmbHin group Erste Asset Management GmbH50,000$1.95M0.02%013F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.48,455$1.95M<0.01%-93,32813F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…45,907$1.84M<0.01%-176,44513F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…44,221$1.78M0.01%-1,32613F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/41,692$1.68M<0.01%+3,75713F-HRTimeline
Artia Global Partners LP40,000$1.61M0.28%013F-HR/ATimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding38,282$1.54M-6,330Timeline
Atika Capital Management LLCin group Atika Capital Management LLC38,000$1.53M0.13%new13F-HRTimelineGroup
DekaBank Deutsche Girozentrale39,000$1.51M<0.01%013F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC37,448$1.5M<0.01%-1,95513F-HRTimelineGroup
ALPS ADVISORS INCin group ALPS ADVISORS INC37,300$1.5M0.01%-4,08013F-HRTimelineGroup
TLS Advisors LLC32,956$1.38M4.02%013F-HRTimeline
J. Safra Sarasin Holding AGin group J. Safra Sarasin Holding AG30,168$1.21M0.02%-51,88013F-HRTimelineGroup
BAMCO INC /NY/in group Baron Capital30,000$1.2M<0.01%-26,00013F-HRTimelineGroup
BOOTHBAY FUND MANAGEMENT, LLC28,859$1.16M0.03%new13F-HRTimeline
Campbell & CO Investment Adviser LLC28,669$1.15M0.09%new13F-HRTimeline
HighMark Wealth Management LLC26,100$1.05M0.46%013F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…25,589$1.03M<0.01%+1,72313F-HRTimeline
NJ State Employees Deferred Compensatio…25,000$1M0.11%013F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …23,932$961K<0.01%-2,14713F-HRTimelineGroup
Rathbones Group PLC23,666$950K<0.01%013F-HRTimeline
Man Group plcin group Man Group plc23,119$928K<0.01%-39,22913F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC23,086$927K0.01%-11,22613F-HRTimeline
Cinctive Capital Management LP23,054$926K0.05%new13F-HRTimeline
Handelsbanken Fonder AB22,700$911K<0.01%013F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC22,566$906K<0.01%+1,31613F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO22,423$900K<0.01%-30013F-HRTimelineGroup
OXFORD ASSET MANAGEMENT LLP22,162$890K0.29%+1,02413F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
SANDERS MORRIS HARRIS LLC21,500$863K0.11%new13F-HRTimeline
Police & Firemen's Retirement System of…21,032$844K0.01%+3,67413F-HRTimeline
Birchview Capital, LP21,000$843K0.64%013F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM19,290$774K<0.01%+33413F-HRTimeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP18,715$751K<0.01%-1,90713F-HRTimelineGroup
TWO SIGMA ADVISERS, LPin group TWO SIGMA INVESTMENTS, LP18,100$727K<0.01%-77,20013F-HRTimelineGroup
NATIXIS ADVISORS, LLCin group Natixis Investment Managers17,564$705K<0.01%+14013F-HRTimelineGroup
TD Asset Management Inc16,230$652K<0.01%new13F-HRTimeline
Thrivent Financial for Lutheransin group Thrivent Financial for Luther…16,101$647K<0.01%new13F-HRTimelineGroup
TEACHER RETIREMENT SYSTEM OF TEXAS16,001$642K<0.01%-1,53313F-HRTimeline
ProShare Advisors LLC15,740$632K<0.01%-2,70813F-HRTimeline
Ensign Peak Advisors, Inc15,244$612K<0.01%-10,85013F-HR/ATimeline
Orion Porfolio Solutions, LLC14,918$599K<0.01%+213F-HRTimeline
CITIGROUP INCin group CITIGROUP INC14,870$597K<0.01%-21,42013F-HRTimelineGroup
CenterBook Partners LP14,770$593K0.03%-9,89413F-HRTimeline
Legato Capital Management LLC14,209$570K0.06%+4,58713F-HRTimeline
China Universal Asset Management Co., L…13,515$543K0.04%-1,89713F-HRTimeline
CIBC WORLD MARKET INC.13,460$540K<0.01%-2,87513F-HRTimeline
Quantinno Capital Management LP13,371$537K<0.01%new13F-HRTimeline
Creative Planningin group Creative Planning13,210$530K<0.01%new13F-HRTimelineGroup
KLP KAPITALFORVALTNING AS12,800$514K<0.01%013F-HRTimeline
Schonfeld Strategic Advisors LLC12,652$508K<0.01%+2,11413F-HRTimeline
Advisors Asset Management, Inc.11,464$460K0.01%-74113F-HR/ATimeline
HARBOR CAPITAL ADVISORS, INC.11,218$450K0.03%-18,81813F-HRTimeline
Supplemental Annuity Collective Trust o…11,000$442K0.12%013F-HRTimeline
Knott David M Jr10,962$440K0.18%013F-HRTimeline
Elmwood Wealth Management, Inc.10,907$438K0.16%+8313F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…10,633$427K<0.01%013F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE9,400$377K<0.01%013F-HRTimelineGroup
DRW Securities, LLC9,273$374K0.02%new13F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC8,850$355K<0.01%-38,90513F-HRTimelineGroup
CIBC Bancorp USA Inc.in group CIBC Bancorp USA Inc.8,100$325K<0.01%13F-HR/ATimelineGroup
ALTFEST L J & CO INC7,731$310K0.03%new13F-HRTimeline
SG Americas Securities, LLC6,928$278K<0.01%-12,24913F-HRTimeline
PenderFund Capital Management Ltd.6,850$275K0.05%new13F-HRTimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co7,024$274K<0.01%013F-HRTimelineGroup
Freestone Grove Partners LP6,748$271K<0.01%new13F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…6,558$263K0.01%-1,20013F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC6,500$261K<0.01%-10,49113F-HR/ATimelineGroup
INCEPTIONR LLC6,322$254K0.06%new13F-HRTimeline
XPONANCE LLC5,967$240K<0.01%new13F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…5,899$237K<0.01%+2,43713F-HRTimelineGroup
PRINCIPAL FINANCIAL GROUP INCgroup of 2 filers holding5,886$236K+5,818Timeline
RENAISSANCE TECHNOLOGIES LLC5,200$209K<0.01%-3,40013F-HRTimeline
EntryPoint Capital, LLC5,028$202K0.08%new13F-HRTimeline
CITIZENS FINANCIAL GROUP INC/RIin group CITIZENS FINANCIAL GROUP INC/…5,000$201K<0.01%new13F-HRTimelineGroup
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…5,000$201K<0.01%013F-HRTimelineGroup
GROUP ONE TRADING LLC3,556$143K<0.01%-1,09713F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…3,469$139K0.04%+60213F-HRTimelineGroup
AMALGAMATED BANK2,595$104K<0.01%013F-HRTimeline
Quarry LP2,500$100K0.02%+50013F-HRTimeline
IFP Advisors, Inc1,908$76.6K<0.01%+4313F-HR/ATimeline
KBC Group NVin group KBC Group NV1,871$75K<0.01%013F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.1,659$66.6K<0.01%-29313F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,517$60.9K<0.01%-3,84013F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.1,374$55K<0.01%+14913F-HRTimelineGroup
State of Wyoming1,151$46.2K0.01%+61013F-HRTimeline
Aster Capital Management (DIFC) Ltd959$38.5K0.02%new13F-HRTimeline
NISA INVESTMENT ADVISORS, LLC924$37.1K<0.01%+23513F-HRTimeline
Farther Finance Advisors, LLC846$34K<0.01%+6213F-HRTimeline
DANSKE BANK A/S800$32.1K<0.01%013F-HR/ATimeline
SIGNATUREFD, LLC416$16.7K<0.01%-24513F-HRTimeline
Clearstead Advisors, LLC386$15.5K<0.01%+3913F-HRTimeline
CWM, LLCin group CWM, LLC335$13K<0.01%+9813F-HRTimelineGroup
Mitsubishi UFJ Asset Management Co., Lt…in group Mitsubishi UFJ Trust & Bankin…276$11.1K<0.01%013F-HRTimelineGroup
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.252$10K<0.01%013F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…200$8.03K<0.01%new13F-HRTimelineGroup
United Community Bankin group United Community Bank200$8.03K<0.01%013F-HRTimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/200$8.03K<0.01%-3513F-HRTimelineGroup
GAMMA Investing LLC185$7.43K<0.01%+17113F-HRTimeline
Sterling Capital Management LLC184$7.39K<0.01%013F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\175$7.03K<0.01%-613F-HRTimelineGroup
Parallel Advisors, LLC147$5.9K<0.01%+1213F-HRTimeline