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Disclosery

TRVI TREVI THERAPEUTICS INC

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Stock (common), issuer CIK 1563880

182 managers (185 13F filers) reported a position in TRVI shares at 2025-12-31, 130,341,496 shares in all. 29 filers opened a position and 14 filers sold out during the quarter.

Managers
182
13F filers
185
New
29
Added
75
Reduced
48
Sold out
14
Shares held by filers
130,341,496

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
NEA Management Company, LLC13,222,228$166M8.44%013F-HRTimeline
Frazier Life Sciences Management, L.P.10,259,409$128M3.45%013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.10,126,183$127M<0.01%+225,13013F-HRTimelineGroup
FMR LLCin group FMR LLC6,500,009$81.4M<0.01%+3,200,11813F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC6,434,655$80.6M<0.01%+607,66913F-HRTimelineGroup
Vivo Capital, LLC5,094,668$63.8M4.12%013F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP4,580,548$57.3M0.06%-261,20313F-HRTimelineGroup
Rubric Capital Management LP3,766,749$47.2M0.56%-4,765,11113F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…3,403,990$42.6M0.01%+150,10213F-HRTimelineGroup
MPM BIOIMPACT LLC3,287,087$41.2M4.71%-119,86813F-HRTimeline
VIKING GLOBAL INVESTORS LPin group VIKING GLOBAL INVESTORS LP3,198,644$40M0.11%-1,930,23113F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC3,190,700$39.9M0.82%-117,70013F-HRTimelineGroup
EMERALD ADVISERS, LLCgroup of 2 filers holding3,164,649$39.6MnewTimeline
ALLIANCEBERNSTEIN L.P.3,082,986$38.6M0.01%-1,209,46513F-HRTimeline
Octagon Capital Advisors LP2,815,000$35.2M4.41%013F-HRTimeline
EVENTIDE ASSET MANAGEMENT, LLC2,622,306$32.8M0.51%+1,240,98213F-HRTimeline
STATE STREET CORPin group STATE STREET CORP2,435,000$30.5M<0.01%+215,57813F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC2,412,885$30.2M<0.01%+191,95913F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.2,286,867$28.6M0.85%-250,00013F-HRTimelineGroup
Affinity Asset Advisors, LLC2,150,172$26.9M1.93%-649,82813F-HRTimeline
ACORN CAPITAL ADVISORS, LLC2,144,844$26.9M9.1%013F-HRTimeline
Artia Global Partners LP2,013,602$25.2M4.05%+13,90013F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC1,766,963$22.1M0.01%+355,92613F-HRTimelineGroup
Logos Global Management LP1,550,000$19.4M1.29%-650,00013F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…1,532,013$19.2M0.02%+1,520,75413F-HRTimelineGroup
Pivotal bioVenture Partners Investment …in group Pivotal bioVenture Partners I…1,256,782$15.7M6.08%013F-HRTimelineGroup
FRONTIER CAPITAL MANAGEMENT CO LLC1,108,468$13.9M0.15%new13F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/1,094,851$13.7M<0.01%-741,98813F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC1,056,891$13.2M<0.01%+269,43713F-HR/ATimelineGroup
FLPUTNAM INVESTMENT MANAGEMENT CO1,053,427$13.2M0.19%+5,32513F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY1,050,296$13.1M<0.01%-3,251,43013F-HR/ATimelineGroup
Woodline Partners LP1,000,282$12.5M0.05%+900,00013F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.1,000,000$12.5M0.02%+58,07113F-HRTimelineGroup
NAN FUNG TRINITY (HK) LTD917,450$11.5M0.91%+827,87513F-HRTimeline
Soleus Capital Management, L.P.900,000$11.3M0.48%+875,00013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co836,800$10.5M<0.01%+30,46913F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…825,548$10.3M0.01%-775,19413F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP761,966$9.54M<0.01%+25,03613F-HRTimelineGroup
PANAGORA ASSET MANAGEMENT INC693,001$8.68M0.03%+122,53313F-HRTimeline
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.598,534$7.49M1.57%-45,42313F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC582,653$7.29M<0.01%+365,76813F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC570,226$7.14M0.01%-157,37013F-HRTimelineGroup
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC549,219$6.88M0.01%-53,43513F-HRTimelineGroup
Informed Momentum Co LLC541,242$6.78M0.75%-8,23713F-HRTimeline
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…541,240$6.78M0.98%-47,54913F-HRTimelineGroup
Burkehill Global Management, LP525,000$6.57M0.43%013F-HRTimeline
PEREGRINE CAPITAL MANAGEMENT LLC507,685$6.36M0.19%-112,77913F-HRTimeline
Invesco Ltd.in group Invesco Ltd.498,926$6.25M<0.01%+15,85613F-HRTimelineGroup
J. Goldman & Co LP444,357$5.56M0.22%-348,44913F-HRTimeline
UBS Group AGgroup of 2 filers holding415,361$5.2M+272Timeline
KVP Capital Advisors, LP414,000$5.18M5.35%13F-HRTimeline
STEMPOINT CAPITAL LP399,557$5M0.86%+48,84713F-HRTimeline
Opaleye Management Inc.345,100$4.32M0.57%-44,90013F-HR/ATimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC324,172$4.06M<0.01%new13F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp260,587$3.26M<0.01%+34,24813F-HRTimelineGroup
F/m Investments LLC241,483$3.02M0.11%new13F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC226,215$2.83M<0.01%+211,03513F-HRTimelineGroup
Velan Capital Investment Management LP205,000$2.57M1.49%013F-HRTimeline
Nuveen, LLCin group TIAA183,329$2.3M<0.01%013F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management174,641$2.19M<0.01%-451,82113F-HRTimelineGroup
Swiss National Bank168,200$2.11M<0.01%+6,50013F-HRTimeline
FRED ALGER MANAGEMENT, LLCin group FRED ALGER MANAGEMENT, LLC157,980$1.98M0.01%-33,06513F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC152,855$1.91M<0.01%+50,32113F-HRTimelineGroup
SUPERSTRING CAPITAL MANAGEMENT LP148,292$1.86M0.99%new13F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO147,941$1.85M<0.01%+62,14313F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.141,312$1.77M<0.01%new13F-HRTimelineGroup
BIT Capital GmbH130,000$1.63M0.07%+123,26113F-HRTimeline
HRT FINANCIAL LP125,104$1.57M<0.01%new13F-HRTimeline
SG Americas Securities, LLC124,562$1.56M<0.01%+60,01713F-HRTimeline
CITIGROUP INCin group CITIGROUP INC123,498$1.55M<0.01%+96,58513F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD120,566$1.51M<0.01%-2,71013F-HRTimeline
HighVista Strategies LLC106,159$1.33M0.34%new13F-HRTimeline
RHUMBLINE ADVISERS105,922$1.33M<0.01%-9,10013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN101,279$1.27M<0.01%+45,59313F-HRTimelineGroup
OPPENHEIMER & CO INCin group OPPENHEIMER ASSET MANAGEMENT …100,698$1.26M0.02%+2,03013F-HRTimelineGroup
LMR Partners LLPin group LMR Partners LLP100,000$1.25M0.01%013F-HRTimelineGroup
Rosalind Advisors, Inc.100,000$1.25M0.46%013F-HRTimeline
DIADEMA PARTNERS LP97,184$1.22M0.72%+11,35413F-HRTimeline
Erste Asset Management GmbHin group Erste Asset Management GmbH90,000$1.15M0.01%new13F-HRTimelineGroup
SECTORAL ASSET MANAGEMENT INC84,255$1.05M0.85%-21,69513F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd83,818$1.05M0.03%new13F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…83,788$1.05M<0.01%+2,09113F-HRTimeline
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP83,755$1.05M<0.01%-36,17513F-HRTimelineGroup
COMERICA BANK83,027$1.04M<0.01%+82,60313F-HRTimeline
WEXFORD CAPITAL LP82,034$1.03M0.26%new13F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc81,673$1.02M<0.01%-29913F-HRTimelineGroup
PFS Partners, LLC79,000$989K0.45%013F-HRTimeline
MAI Capital Management77,769$974K0.01%-20,72313F-HRTimeline
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…75,000$939K0.01%new13F-HRTimelineGroup
Campbell & CO Investment Adviser LLC71,097$890K0.04%+46,21213F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\70,833$887K<0.01%+19,19313F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL68,481$857K<0.01%new13F-HRTimeline
WealthTrust Axiom LLC61,500$770K0.2%013F-HRTimeline
OPTIMIZE FINANCIAL INC.61,483$770K0.39%+88413F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO59,475$745K<0.01%+66013F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…59,444$744K<0.01%+2,98413F-HRTimelineGroup
KENNEDY CAPITAL MANAGEMENT LLC56,269$704K0.01%+1,33613F-HRTimeline
LPL Financial LLC52,960$663K<0.01%+12,51013F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE52,800$661K<0.01%new13F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/50,273$630K<0.01%+3,41413F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…50,250$629K<0.01%-50213F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources49,878$624K<0.01%013F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding48,294$605K+2,961Timeline
SIMPLEX TRADING, LLC47,134$590K0.02%-16,01513F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…46,681$584K<0.01%+21,50313F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC45,995$576K<0.01%new13F-HRTimelineGroup
Persistent Asset Partners Ltd45,830$574K0.28%+26,14213F-HRTimeline
Steward Partners Investment Advisory, L…44,095$552K<0.01%+12,50013F-HRTimeline
Creative Planningin group Creative Planning40,222$504K<0.01%+14,04713F-HRTimelineGroup
Z3 Capital Partners, LLC39,450$494K0.12%13F-HRTimeline
IMC-Chicago, LLC38,827$486K0.01%+8,22513F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson37,127$464K<0.01%013F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP36,510$457K<0.01%-4,93313F-HRTimelineGroup
TRUST CO OF TOLEDO NA /OH/36,502$457K0.05%013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA33,119$415K<0.01%-135,87513F-HRTimelineGroup
Verition Fund Management LLC32,119$402K<0.01%new13F-HRTimeline
FOX RUN MANAGEMENT, L.L.C.31,346$392K0.06%new13F-HRTimeline
UNITED BANK31,200$391K0.05%013F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC29,202$366K<0.01%-13,60813F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC29,070$364K<0.01%+3,74113F-HRTimeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP28,288$354K<0.01%+5,38713F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …27,937$350K<0.01%-1,67813F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND27,765$348K<0.01%013F-HRTimeline
Harbour Capital Advisors, LLC27,500$327K0.07%013F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM24,063$301K<0.01%-59913F-HRTimeline
Police & Firemen's Retirement System of…23,777$298K<0.01%013F-HRTimeline
STRS OHIO23,700$297K<0.01%-8,60013F-HRTimeline
AlphaCentric Advisors LLC22,667$284K0.28%13F-HRTimeline
Qube Research & Technologies Ltd22,622$283K<0.01%-629,05713F-HRTimeline
ProShare Advisors LLC22,269$279K<0.01%+2,94713F-HRTimeline
AXQ CAPITAL, LP22,204$278K0.06%+6,68013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS22,056$276K<0.01%+3,84413F-HRTimelineGroup
DIVERSIFIED TRUST CO20,984$263K<0.01%+2,67513F-HRTimeline
China Universal Asset Management Co., L…20,895$262K0.02%-45113F-HRTimeline
CHAPIN DAVIS, INC.20,100$252K0.06%-15,00013F-HRTimeline
DYMON ASIA CAPITAL (SINGAPORE) PTE. LTD.in group DYMON ASIA CAPITAL (SINGAPORE…20,000$250K0.06%new13F-HRTimelineGroup
PROFUND ADVISORS LLC19,378$243K0.01%-72513F-HRTimeline
KLP KAPITALFORVALTNING AS18,300$229K<0.01%+90013F-HRTimeline
LANARK FINANCIAL, INC.17,000$213K0.02%+15,00013F-HRTimeline
Rafferty Asset Management, LLC16,499$207K<0.01%+2,93313F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS12,603$158K<0.01%-7,61613F-HRTimeline
Vontobel Holding Ltd.in group Vontobel Holding Ltd.10,764$135K<0.01%-11,09513F-HRTimelineGroup
Kingsview Wealth Management, LLC10,638$133K<0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…10,461$131K<0.01%+7,67513F-HRTimelineGroup
Abel Hall, LLC10,191$128K0.03%new13F-HRTimeline
DLD Asset Management, LP10,000$125K0.01%-45,00013F-HRTimeline
Farther Finance Advisors, LLC9,270$116K<0.01%+43213F-HRTimeline
AlphaQuest LLC7,988$100K0.01%-70913F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…7,632$95.6K<0.01%013F-HRTimelineGroup
Bellevue Group AGin group Bellevue Group AG7,603$95.2K<0.01%new13F-HRTimelineGroup
Seven Fleet Capital Management LP7,110$89K0.06%13F-HR/ATimeline
Caitong International Asset Management …4,022$50.4K0.01%new13F-HR/ATimeline
Hilton Head Capital Partners, LLC3,206$40.1K0.02%13F-HRTimeline
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/2,967$37.1K<0.01%+3113F-HRTimelineGroup
AMALGAMATED BANK2,852$36K<0.01%+28413F-HRTimeline
GF FUND MANAGEMENT CO. LTD.2,519$31.5K<0.01%-10113F-HRTimeline
Chung Wu Investment Group, LLC2,000$25K0.02%+40013F-HRTimeline
Aquatic Capital Management LLC1,978$24.8K<0.01%new13F-HRTimeline
BESSEMER GROUP INCin group BESSEMER GROUP INC1,560$20K<0.01%new13F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…999$12.5K<0.01%+41413F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC899$11.3K<0.01%+73013F-HRTimeline
SIGNATUREFD, LLC835$10.5K<0.01%+16113F-HRTimeline
QUADRANT CAPITAL GROUP LLC789$9.88K<0.01%013F-HRTimeline
Allworth Financial LP753$9.43K<0.01%+70013F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP620$7.76K<0.01%-47413F-HRTimelineGroup
Aster Capital Management (DIFC) Ltd602$7.54K<0.01%new13F-HRTimeline
Sterling Capital Management LLC581$7.27K<0.01%+36913F-HRTimeline
MassMutual Private Wealth & Trust, FSB516$6.46K<0.01%013F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.427$5K<0.01%+12213F-HRTimelineGroup
CWM, LLCin group CWM, LLC381$5K<0.01%+1713F-HRTimelineGroup
Optiver Holding B.V.in group Optiver Holding B.V.378$4.73K<0.01%-51013F-HRTimelineGroup
Arax Advisory Partners206$2.58K<0.01%+2113F-HRTimeline
GAMMA Investing LLC180$2.25K<0.01%+11113F-HRTimeline
Parkside Financial Bank & Trust140$1.75K<0.01%013F-HRTimeline
Cornerstone Financial Management LLC78$977<0.01%13F-HR/ATimeline
LOS ANGELES CAPITAL MANAGEMENT LLC87$972<0.01%new13F-HRTimeline
SageView Advisory Group, LLC49$614<0.01%new13F-HRTimeline
Essential Partners LLC11$138<0.01%013F-HRTimeline
Larson Financial Group LLC9$113<0.01%+613F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\4$50<0.01%013F-HRTimelineGroup
Smartleaf Asset Management LLC1$13<0.01%013F-HRTimeline
NOMURA ASSET MANAGEMENT CO LTDin group NOMURA ASSET MANAGEMENT CO LTD0$00%new13F-HRTimelineGroupValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.