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Disclosery

GPCR STRUCTURE THERAPEUTICS INC

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EQUITY (ADR), issuer CIK 1888886

170 managers (173 13F filers) reported a position in GPCR shares at 2025-06-30, 54,653,189 shares in all. 37 filers opened a position and 16 filers sold out during the quarter.

Managers
170
13F filers
173
New
37
Added
63
Reduced
43
Sold out
16
Shares held by filers
54,653,189

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2025

Filers in the available 13F reports with a share position at 2025-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…6,875,769$143M0.03%-915,41413F-HRTimelineGroup
Deep Track Capital, LP5,133,917$106M3.42%+1,033,91713F-HRTimeline
FMR LLCin group FMR LLC4,914,965$102M0.01%-968,74213F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson4,573,006$94.9M0.05%+217,81213F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP2,508,767$52M0.5%+2,147,20213F-HRTimelineGroup
BVF INC/ILin group BVF INC/IL1,771,417$36.7M1.31%013F-HRTimelineGroup
Capital International Investorsin group Capital International Investo…1,618,876$33.6M0.01%-15013F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC1,588,198$32.9M0.01%+106,38913F-HRTimelineGroup
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.1,517,418$31.5M0.53%013F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC1,328,479$27.6M0.02%+336,13913F-HRTimelineGroup
Casdin Capital, LLC1,225,000$25.4M2.31%+525,00013F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC1,220,055$25.3M0.02%+429,89613F-HRTimelineGroup
Vestal Point Capital, LP1,200,000$24.9M1.31%-588,99013F-HRTimeline
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC1,199,300$24.9M0.63%+547,27213F-HRTimelineGroup
Rock Springs Capital Management LP1,135,879$23.6M1.47%+2,90013F-HRTimeline
TCG Crossover Management, LLC1,063,000$22M2.52%013F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY917,346$19M<0.01%+224,90713F-HRTimelineGroup
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC853,202$17.7M0.01%+96,49513F-HRTimelineGroup
Logos Global Management LP850,000$17.6M2.35%+425,00013F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources741,783$15.4M<0.01%+1,63113F-HRTimelineGroup
Driehaus Capital Management LLC672,792$14M0.11%-599,95113F-HRTimeline
Catalio Capital Management, LP670,575$13.9M2.92%-34,28913F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC491,193$10.2M0.01%-19,00813F-HRTimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.468,300$9.71M0.02%-702,64813F-HRTimelineGroup
Pacific Heights Asset Management LLC460,000$9.54M0.51%new13F-HRTimeline
Monashee Investment Management LLC430,000$8.92M4.71%+137,13813F-HRTimeline
Invesco Ltd.in group Invesco Ltd.424,548$8.81M<0.01%+30,16213F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc401,624$8.33M0.01%+152,72513F-HRTimelineGroup
Handelsbanken Fonder AB380,000$7.88M0.03%013F-HRTimeline
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…373,407$7.74M0.14%013F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/352,868$7.32M<0.01%-424,30513F-HRTimeline
Bellevue Group AGin group Bellevue Group AG348,527$7.23M0.16%+126,81213F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.330,000$6.84M0.02%+100,56913F-HRTimelineGroup
Schonfeld Strategic Advisors LLC321,591$6.67M0.05%new13F-HRTimeline
ArrowMark Colorado Holdings LLC298,937$6.2M0.11%+53,75113F-HRTimeline
HSG Holding Ltdin group HSG Holding Ltd266,062$5.52M0.28%013F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 3 filers holding255,479$5.3M+29,351Timeline
BlackRock, Inc.in group BlackRock, Inc.243,334$5.05M<0.01%-323,17113F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC220,174$4.57M<0.01%-104,26113F-HRTimelineGroup
Foresite Capital Management VI LLCin group Foresite Capital Management V…210,000$4.36M2.45%-210,00013F-HRTimelineGroup
Pier Capital, LLC198,478$4.12M0.63%-14,04213F-HRTimeline
Ikarian Capital, LLCin group Ikarian Capital, LLC183,085$3.8M1.26%-81,00013F-HRTimelineGroup
READYSTATE ASSET MANAGEMENT LP178,612$3.7M0.15%-302,62913F-HRTimeline
Woodline Partners LP176,453$3.66M0.02%+1,02913F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP176,060$3.65M<0.01%+145,43413F-HRTimelineGroup
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…175,636$3.64M0.75%-12,43313F-HRTimelineGroup
Nantahala Capital Management, LLCin group Nantahala Capital Management,…168,553$3.5M0.25%013F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD167,800$3.48M<0.01%new13F-HRTimeline
UBS Group AGgroup of 2 filers holding157,151$3.26M-86,961Timeline
CCG WEALTH MANAGEMENT, LLC150,000$3.11M1.64%013F-HRTimeline
Rhenman & Partners Asset Management AB135,100$2.8M0.35%+65,10013F-HRTimeline
First Light Asset Management, LLC122,226$2.53M0.33%-10,15413F-HRTimeline
Point72 Europe (London) LLP116,697$2.42M0.12%+26,00013F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC111,900$2.32M<0.01%+96,10013F-HRTimeline
Eversept Partners, LP99,338$2.06M0.21%new13F-HRTimeline
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.95,931$1.99M0.52%+11,93113F-HRTimelineGroup
HighVista Strategies LLC86,621$1.8M0.66%+69,06013F-HRTimeline
Trexquant Investment LP81,588$1.69M0.02%-38,75213F-HRTimeline
PLATINUM INVESTMENT MANAGEMENT LTD74,900$1.55M0.1%013F-HRTimeline
Verition Fund Management LLC72,984$1.51M0.01%+53,40213F-HRTimeline
Cubist Systematic Strategies, LLC71,690$1.49M0.02%+16,87413F-HRTimeline
BANQUE PICTET & CIE SA70,401$1.46M0.02%-11,36513F-HRTimeline
Jain Global LLC69,369$1.44M0.02%+45,73013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS65,836$1.37M<0.01%+61,31813F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.63,362$1.31M<0.01%+31,97213F-HR/ATimelineGroup
Jump Financial, LLCin group Jump Financial, LLC63,234$1.31M0.02%+32,52413F-HR/ATimelineGroup
EXCHANGE TRADED CONCEPTS, LLC61,732$1.28M0.02%+22,80913F-HRTimeline
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/58,073$1.22M<0.01%+4,83813F-HRTimelineGroup
DAFNA Capital Management LLC59,000$1.22M0.34%013F-HRTimeline
MACQUARIE GROUP LTDin group MACQUARIE GROUP LTD58,000$1.2M<0.01%013F-HRTimelineGroup
BOOTHBAY FUND MANAGEMENT, LLC57,622$1.2M0.04%-19,67213F-HRTimeline
PFM Health Sciences, LP56,594$1.17M0.1%+16,19413F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC54,181$1.12M<0.01%+8,44413F-HRTimelineGroup
Exome Asset Management LLC53,744$1.11M0.92%-49,20013F-HR/ATimeline
SECTORAL ASSET MANAGEMENT INC51,369$1.07M0.7%+17,67413F-HRTimeline
TD Asset Management Inc43,686$906K<0.01%013F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO42,442$880K<0.01%-91,79713F-HRTimelineGroup
Quinn Opportunity Partners LLC42,000$871K0.07%+20,00013F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …40,789$846K<0.01%+5213F-HRTimelineGroup
Mariner, LLCin group Mariner, LLC39,501$819K<0.01%+21,45013F-HRTimelineGroup
Walleye Capital LLCin group Walleye Capital LLC38,673$802K0.01%new13F-HRTimelineGroup
TrueMark Investments, LLCin group TrueMark Investments, LLC37,765$783K0.17%-1,45213F-HRTimelineGroup
TWO SIGMA ADVISERS, LPin group TWO SIGMA INVESTMENTS, LP36,100$749K<0.01%new13F-HRTimelineGroup
Birchview Capital, LP36,000$747K0.74%new13F-HRTimeline
Sofinnova Investments, Inc.34,353$712K0.05%-59913F-HRTimeline
STATE STREET CORPin group STATE STREET CORP33,459$694K<0.01%+22,71913F-HRTimelineGroup
ALPS ADVISORS INCin group ALPS ADVISORS INC31,073$644K<0.01%-12,00713F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC30,655$636K<0.01%+4,71513F-HRTimelineGroup
Caption Management, LLC28,174$584K0.05%+18,91813F-HRTimeline
NOMURA ASSET MANAGEMENT CO LTDin group NOMURA ASSET MANAGEMENT CO LTD24,874$516K<0.01%-4,10013F-HRTimelineGroup
DCF Advisers, LLC24,750$513K0.25%new13F-HRTimeline
OMERS ADMINISTRATION Corp24,600$510K<0.01%new13F-HRTimeline
SIMPLEX TRADING, LLC23,094$478K0.01%+2,49013F-HRTimeline
NEOS Investment Management LLC22,880$475K0.01%+29013F-HRTimeline
Tema ETFs LLC22,880$475K0.13%+29013F-HRTimeline
ALLIANCEBERNSTEIN L.P.22,499$467K<0.01%new13F-HRTimeline
Tejara Capital Ltd22,400$465K0.22%new13F-HRTimeline
Headlands Technologies LLC22,338$463K0.06%+18,93013F-HRTimeline
Paloma Partners Management Coin group Paloma Partners Management Co20,950$435K0.1%new13F-HRTimelineGroup
SG Americas Securities, LLC19,239$399K<0.01%new13F-HRTimeline
TEACHERS RETIREMENT SYSTEM OF THE STATE…17,651$366K<0.01%013F-HRTimeline
PRELUDE CAPITAL MANAGEMENT, LLC17,070$354K0.03%-8,55813F-HRTimeline
Quadrature Capital Ltdin group Quadrature Capital Ltd16,079$334K0.01%new13F-HRTimelineGroup
Engineers Gate Manager LP15,862$329K<0.01%new13F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC15,176$315K<0.01%new13F-HR/ATimelineGroup
Good Life Advisors, LLC15,000$311K0.02%+2,00013F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC15,000$311K0.05%-20,61913F-HRTimelineGroup
Virtu Financial LLCin group Virtu Financial LLC14,779$307K0.02%new13F-HRTimelineGroup
CAPITAL FUND MANAGEMENT S.A.14,350$298K<0.01%-65,30613F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/13,908$288K<0.01%-41,53013F-HRTimelineGroup
MASO CAPITAL PARTNERS Ltd13,000$270K0.48%new13F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.12,165$252K<0.01%+50413F-HRTimelineGroup
China Universal Asset Management Co., L…11,967$248K0.02%+1613F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …11,914$247K<0.01%-64,94913F-HRTimelineGroup
LPL Financial LLC11,599$241K<0.01%new13F-HRTimeline
GRIFFIN ASSET MANAGEMENT, INC.11,205$232K0.03%new13F-HRTimeline
BRANDYWINE MANAGERS, LLCin group BRANDYWINE MANAGERS, LLC11,057$229K0.23%013F-HRTimelineGroup
Atom Investors LP11,027$229K0.02%new13F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE11,000$228K<0.01%new13F-HRTimelineGroup
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC10,676$221K<0.01%new13F-HRTimelineGroup
DNB Asset Management ASin group DNB Asset Management AS10,635$221K<0.01%new13F-HRTimelineGroup
Bleichroeder LP10,000$207K0.05%013F-HRTimeline
PEAK6 LLCin group PEAK6 LLC9,445$196K0.01%013F-HR/ATimelineGroup
Parallel Advisors, LLC8,264$171K<0.01%new13F-HRTimeline
GROUP ONE TRADING LLC8,065$167K0.01%-40,85213F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA7,582$157K<0.01%+3,87113F-HR/ATimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN7,223$150K<0.01%-12213F-HRTimelineGroup
SIGNATUREFD, LLC6,650$138K<0.01%+6,55013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC6,328$131K<0.01%+1,01613F-HR/ATimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC6,229$129K<0.01%new13F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…4,415$91.6K<0.01%+99413F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…4,232$87.8K0.03%-94513F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…4,120$85.4K<0.01%+43513F-HRTimelineGroup
ANTIPODES PARTNERS Ltd2,932$60.8K<0.01%-1,31513F-HRTimeline
Quantbot Technologies LP2,888$59.9K<0.01%-11,51313F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC2,877$59.7K<0.01%+82013F-HRTimelineGroup
Steward Partners Investment Advisory, L…2,640$54.8K<0.01%+12413F-HRTimeline
FNY Investment Advisers, LLC1,700$35K0.01%+50013F-HRTimeline
CITIGROUP INCin group CITIGROUP INC1,600$33.2K<0.01%-103,37513F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.1,525$31.6K<0.01%013F-HRTimeline
State of Wyoming1,330$27.6K<0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…898$18.6K<0.01%+30313F-HRTimelineGroup
Caitong International Asset Management …835$17.3K0.01%+45913F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP767$16.2K<0.01%-2,37913F-HRTimelineGroup
Farther Finance Advisors, LLC670$13.9K<0.01%new13F-HRTimeline
Dynamic Wealth Strategies, LLC550$11.4K0.01%new13F-HRTimeline
SouthState Bank Corpin group SouthState Bank Corp500$10.4K<0.01%new13F-HRTimelineGroup
COUNTRY TRUST BANK500$10.4K<0.01%new13F-HRTimeline
GAMMA Investing LLC481$9.98K<0.01%-2613F-HRTimeline
RHUMBLINE ADVISERS450$9.33K<0.01%013F-HRTimeline
CWM, LLCin group CWM, LLC355$7K<0.01%+25513F-HRTimelineGroup
North Star Investment Management Corp.330$6.84K<0.01%013F-HRTimeline
WOLFF WIESE MAGANA LLC286$5.93K<0.01%+15213F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.226$5K<0.01%013F-HRTimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/200$4.15K<0.01%-2,75713F-HR/ATimelineGroup
Private Wealth Management Group, LLC196$4.07K<0.01%013F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…170$3.53K<0.01%new13F-HRTimelineGroup
Ameritas Advisory Services, LLCin group Ameritas Investment Partners,…100$2.07K<0.01%new13F-HRTimelineGroup
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…58$1.2K<0.01%new13F-HRTimelineGroup
Washington Trust Advisors, Inc.41$850<0.01%013F-HRTimeline
CIBC Private Wealth Group LLCin group CIBC Bancorp USA Inc.33$684<0.01%new13F-HRTimelineGroup
Brooklyn Investment Group32$664<0.01%new13F-HR/ATimeline
Federation des caisses Desjardins du Qu…20$415<0.01%013F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\13$270<0.01%013F-HRTimelineGroup
MAI Capital Management10$208<0.01%013F-HRTimeline
Global Retirement Partners, LLC10$207<0.01%13F-HRTimeline
Cullen/Frost Bankers, Inc.in group Cullen/Frost Bankers, Inc.8$166<0.01%013F-HRTimelineGroup
HUNTINGTON NATIONAL BANKin group HUNTINGTON NATIONAL BANK2$41<0.01%013F-HRTimelineGroup
Point72 Asia (Singapore) Pte. Ltd.1$21<0.01%013F-HRTimeline
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.