13F-HR filed by Rock Springs Capital Management LP
Rock Springs Capital Management LP filed this 13F-HR for the quarter ended 2025-06-30, filed 2025-08-14, with 93 holding rows worth $1,604,789,362.
- Accession
- 0001172661-25-003273
- Filer
- CIK 1595725
- Filed
- 2025-08-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q2 2025
A holdings report, 93 entries on the cover page, a total value of $1,604,789,362 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,604,789,362 with VALUE read as dollars as filed, 13F file number 028-16048. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 175,750 | $96,876,915 | dollars as filed | |
| Eli Lilly and Company | 532457108 | COM | 116,500 | $90,815,245 | dollars as filed | |
| MERUS N V | N5749R100 | COM | 1,063,608 | $55,945,781 | dollars as filed | |
| RHYTHM PHARMACEUTICALS INC | 76243J105 | COM | 861,153 | $54,416,258 | dollars as filed | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 525,000 | $52,836,000 | dollars as filed | |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 1,391,072 | $50,579,378 | dollars as filed | |
| REVOLUTION MEDICINES INC COM | 76155X100 | Stock | 1,330,960 | $48,966,018 | dollars as filed | |
| Intuitive Surgical,Inc. | 46120E602 | COM | 82,000 | $44,559,620 | dollars as filed | |
| MADRIGAL PHARMACEUTICALS INC COM | 558868105 | Stock | 140,296 | $42,459,181 | dollars as filed | |
| MIRUM PHARMACEUTICALS INC | 604749101 | COM | 818,206 | $41,638,503 | dollars as filed | |
| Boston Scientific Corporation | 101137107 | COM | 355,000 | $38,130,550 | dollars as filed | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 217,000 | $37,454,200 | dollars as filed | |
| IRHYTHM HOLDINGS INC COM | 450056106 | Stock | 242,500 | $37,335,300 | dollars as filed | |
| AKERO THERAPEUTICS INC | 00973Y108 | COM | 640,526 | $34,178,467 | dollars as filed | |
| PENUMBRA INC COM | 70975L107 | Stock | 128,500 | $32,976,955 | dollars as filed | |
| AGIOS PHARMACEUTICALS INC | 00847X104 | COM | 989,745 | $32,918,919 | dollars as filed | |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 100,000 | $32,609,000 | dollars as filed | |
| EVOLENT HEALTH INC CL A | 30050B101 | Stock | 2,820,700 | $31,761,082 | dollars as filed | |
| ZAI LAB LTD ADR | 98887Q104 | ADR | 871,392 | $30,472,578 | dollars as filed | |
| EXACT SCIENCES CORP COM | 30063P105 | Stock | 572,000 | $30,396,080 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 931,681 | $29,161,615 | dollars as filed | |
| TRAVERE THERAPEUTICS INC | 89422G107 | COM | 1,908,208 | $28,241,478 | dollars as filed | |
| SCHOLAR ROCK HLDG CORP | 80706P103 | COM | 794,133 | $28,128,191 | dollars as filed | |
| DEXCOM INC COM | 252131107 | Stock | 286,750 | $25,030,408 | dollars as filed | |
| PHREESIA INC | 71944F106 | COM | 837,300 | $23,829,558 | dollars as filed | |
| BLUEPRINT MEDICINES CORP | 09627Y109 | COM | 185,500 | $23,777,390 | dollars as filed | |
| STRUCTURE THERAPEUTICS INC COMP | 86366E106 | EQUITY | 1,135,879 | $23,558,130 | dollars as filed | |
| TENET HEALTHCARE CORP COM NEW | 88033G407 | Stock | 130,000 | $22,880,000 | dollars as filed | |
| CARIS LIFE SCIENCES INC | 142152107 | COMMON STOCK | 793,651 | $21,206,355 | dollars as filed | |
| KYMERA THERAPEUTICS INC | 501575104 | COM | 450,374 | $19,654,321 | dollars as filed | |
| OMADA HEALTH INC | 68170A108 | COM | 919,951 | $16,835,103 | dollars as filed | |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 812,653 | $16,537,489 | dollars as filed | |
| AZENTA INC | 114340102 | COM | 530,400 | $16,325,712 | dollars as filed | |
| ACADIA HEALTHCARE COMPANY INC COM | 00404A109 | Stock | 696,000 | $15,792,240 | dollars as filed | |
| UnitedHealth Group Inc | 91324P102 | COM | 50,500 | $15,754,485 | dollars as filed | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 373,750 | $15,140,613 | dollars as filed | |
| SUMMIT THERAPEUTICS INC | 86627T108 | COM | 710,000 | $15,108,800 | dollars as filed | |
| AGILON HEALTH INC | 00857U107 | COM | 6,550,400 | $15,065,920 | dollars as filed | |
| OSCAR HEALTH INC | 687793109 | CL A | 700,000 | $15,008,000 | dollars as filed | |
| VERA THERAPEUTICS INC | 92337R101 | COMMON STOCK | 617,396 | $14,545,850 | dollars as filed | |
| ENLIVEN THERAPEUTICS INC COM | 29337E102 | Stock | 701,408 | $14,070,244 | dollars as filed | |
| INSPIRE MED SYS INC COM | 457730109 | Stock | 107,500 | $13,950,275 | dollars as filed | |
| SOLENO THERAPEUTICS INC | 834203309 | COM | 154,528 | $12,946,356 | dollars as filed | |
| COMPASS THERAPEUTICS INC | 20454B104 | COM | 4,962,955 | $12,903,683 | dollars as filed | |
| SPDR SER TR | 78464A870 | S&P BIOTECH | 151,750 | $12,584,628 | dollars as filed | |
| ARCELLX INC COMMON STOCK | 03940C100 | Stock | 186,314 | $12,268,777 | dollars as filed | |
| MEREO BIOPHARMA GROUP PLC | 589492107 | CMN | 4,465,292 | $12,100,941 | dollars as filed | |
| Danaher Corporation | 235851102 | COM | 59,000 | $11,654,860 | dollars as filed | |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 1,960,334 | $11,232,714 | dollars as filed | |
| WEST PHARMACEUTICAL SVSC INC COM | 955306105 | Stock | 51,030 | $11,165,364 | dollars as filed | |
| NEUROCRINE BIOSCIENCES INC | 64125C109 | COM | 88,800 | $11,161,272 | dollars as filed | |
| PHARVARIS NV | N69605108 | COMMON STOCK | 623,402 | $10,971,875 | dollars as filed | |
| EDWARDS LIFESCIENCES CORP COM | 28176E108 | Stock | 131,000 | $10,245,510 | dollars as filed | |
| NEWAMSTERDAM PHARMA CO NV | N62509109 | COMMON STOCK | 536,111 | $9,708,970 | dollars as filed | |
| ARDELYX INC | 039697107 | COM | 2,286,273 | $8,962,190 | dollars as filed | |
| NUVALENT INC COM | 670703107 | Stock | 93,328 | $7,120,926 | dollars as filed | |
| ACLARIS THERAPEUTICS INC COM | 00461U105 | Stock | 4,769,309 | $6,772,419 | dollars as filed | |
| CIDARA THERAPEUTICS INC | 171757206 | COM NEW | 134,133 | $6,533,618 | dollars as filed | |
| ZENAS BIOPHARMA INC COM | 98937L105 | Stock | 640,467 | $6,206,125 | dollars as filed | |
| REGENERON PHARMACEUTICALS COM | 75886F107 | Stock | 11,300 | $5,932,500 | dollars as filed | |
| COGENT BIOSCIENCES INC | 19240Q201 | COM | 800,199 | $5,745,429 | dollars as filed | |
| DYNE THERAPEUTICS INC COM | 26818M108 | Stock | 580,998 | $5,531,101 | dollars as filed | |
| CULLINAN THERAPEUTICS INC | 230031106 | COM | 668,233 | $5,031,794 | dollars as filed | |
| GOSSAMER BIO INC | 38341PAA0 | NOTE 5.000% 6/0 | 9,573,000 | $4,952,132 | dollars as filed | principal |
| JANUX THERAPEUTICS INC | 47103J105 | COM | 210,266 | $4,857,145 | dollars as filed | |
| MINERALYS THERAPEUTICS INC | 603170101 | COM | 324,513 | $4,390,661 | dollars as filed | |
| Thermo Fisher Scientific Inc. | 883556102 | COM | 10,000 | $4,054,600 | dollars as filed | |
| GOSSAMER BIO INC COM | 38341P102 | Stock | 3,266,960 | $4,018,361 | dollars as filed | |
| IMMUNOVANT INC | 45258J102 | COM | 221,500 | $3,544,000 | dollars as filed | |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 499,764 | $3,203,487 | dollars as filed | |
| BICARA THERAPEUTICS INC | 055477103 | COM | 336,070 | $3,122,090 | dollars as filed | |
| JASPER THERAPEUTICS INC | 471871202 | COM NEW | 545,171 | $3,025,699 | dollars as filed | |
| PROTHENA CORP PLC SHS | G72800108 | Stock | 492,601 | $2,990,088 | dollars as filed | |
| ALPHATEC HLDGS INC | 02081G201 | COM NEW | 267,500 | $2,969,250 | dollars as filed | |
| LENZ THERAPEUTICS INC | 52635N103 | COM | 83,982 | $2,461,512 | dollars as filed | |
| EDAP TMS S A | 268311107 | SPONSORED ADR | 1,270,000 | $2,095,500 | dollars as filed | |
| COMPUGEN LTD | M25722105 | ORD | 989,990 | $1,762,182 | dollars as filed | |
| SIONNA THERAPEUTICS INC | 829401108 | COMMON STOCK | 99,429 | $1,725,093 | dollars as filed | |
| PULMONX CORP | 745848101 | COM | 651,100 | $1,686,349 | dollars as filed | |
| NEUROGENE INC | 64135M105 | COMMON STOCK | 104,339 | $1,559,868 | dollars as filed | |
| PERSPECTIVE THERAPEUTICS INC | 46489V302 | COMMON STOCK | 444,383 | $1,528,678 | dollars as filed | |
| APELLIS PHARMACEUTICALS INC | 03753U106 | COM | 84,300 | $1,459,233 | dollars as filed | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 68,600 | $1,173,060 | dollars as filed | |
| Mersana Therapeutics Inc | 59045L106 | Common Stock | 3,814,684 | $1,129,146 | dollars as filed | |
| Applied Therapeutics Inc | 03828A101 | Common Stock | 2,075,991 | $645,841 | dollars as filed | |
| ADAPTIMMUNE THERAPEUTICS PLC | 00653A107 | SPONDS ADR | 2,483,468 | $595,287 | dollars as filed | |
| KORRO BIO INC | 500946108 | COMMON STOCK | 35,719 | $446,130 | dollars as filed | |
| CHARLES RIV LABS INTL INC | 159864107 | COM | 2,700 | $409,671 | dollars as filed | |
| 89BIO INC | 282559103 | COM | 40,000 | $392,800 | dollars as filed | |
| VAXCYTE INC COM | 92243G108 | Stock | 11,100 | $360,861 | dollars as filed | |
| NOVAVAX INC | 670002401 | COM NEW | 53,900 | $339,570 | dollars as filed | |
| TALPHERA INC | 00444T209 | COM NEW | 316,460 | $145,635 | dollars as filed | |
| NUVATION BIO INC | 67080N119 | WARR | 134,028 | $36,174 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001172661-25-003273 | this filing | 2025-08-14 | acceptance time not in the bulk data set |