Skip to content
Disclosery

GPCR STRUCTURE THERAPEUTICS INC

Follow

EQUITY (ADR), issuer CIK 1888886

194 managers (196 13F filers) reported a position in GPCR shares at 2026-03-31, 66,716,498 shares in all. 37 filers opened a position and 39 filers sold out during the quarter.

Managers
194
13F filers
196
New
37
Added
72
Reduced
58
Sold out
39
Shares held by filers
66,716,498

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2026

Filers in the available 13F reports with a share position at 2026-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC8,403,449$405M0.02%-308,80213F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…7,260,287$350M0.07%+138,30313F-HRTimelineGroup
Avoro Capital Advisors LLC6,555,555$316M3.11%013F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson5,354,981$258M0.12%+264,83313F-HR/ATimelineGroup
Deep Track Capital, LP4,279,848$206M4.26%+168,06613F-HRTimeline
BVF INC/ILin group BVF INC/IL3,459,358$167M5.31%-19,66413F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY2,305,457$111M0.01%+217,62313F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/2,000,696$96.4M0.01%+329,55813F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC1,753,764$84.5M0.05%+469,55413F-HRTimelineGroup
Driehaus Capital Management LLC1,577,356$76M0.56%-65,08813F-HRTimeline
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC1,475,403$71.1M1.55%+313,60013F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC1,438,031$69.3M0.04%+931,07213F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP1,432,529$69M0.4%013F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.1,328,698$64M1.78%+250,00013F-HRTimelineGroup
Casdin Capital, LLC1,175,000$56.6M4.29%013F-HRTimeline
CAPITOLIS LIQUID GLOBAL MARKETS LLCin group CAPITOLIS LIQUID GLOBAL MARKE…1,151,300$55.5M0.35%13F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.638,813$44.4M0.01%-210,03813F-HRTimeline
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…767,993$37M0.44%013F-HRTimelineGroup
Pacific Heights Asset Management LLC750,000$36.1M1.21%+50,00013F-HRTimeline
Rock Springs Capital Management LP640,217$30.9M1.82%-108,01913F-HRTimeline
Paradigm Biocapital Advisors LPin group Paradigm Biocapital Advisors …545,287$26.3M0.54%new13F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources531,595$25.6M0.01%-338,98713F-HRTimelineGroup
Logos Global Management LP500,000$24.1M1.24%-100,00013F-HRTimeline
HEALTHCARE OF ONTARIO PENSION PLAN TRUS…467,800$22.5M0.04%013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.441,975$21.3M<0.01%+11,89313F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc391,809$18.9M0.03%+126,94013F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\331,867$16M0.01%-509,29513F-HRTimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/305,400$14.7M0.02%+40,00013F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management304,934$14.7M0.03%+88,73513F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC260,543$12.6M<0.01%+36,21113F-HRTimelineGroup
Catalio Capital Management, LP255,379$12.3M2.57%+2,47813F-HRTimeline
VOLORIDGE INVESTMENT MANAGEMENT, LLC254,969$12.3M0.05%+4,96913F-HRTimeline
SEB Asset Management AB245,043$11.8M0.05%13F-HRTimeline
Pentwater Capital Management LP245,000$11.8M0.08%new13F-HRTimeline
Parkman Healthcare Partners LLC232,093$11.2M1.16%+177,09313F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/227,132$10.9M<0.01%+195,45413F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC219,516$10.6M<0.01%-66,00213F-HR/ATimelineGroup
UBS Group AGin group UBS Group AG212,919$10.3M<0.01%+10,44213F-HRTimelineGroup
Sio Capital Management, LLC209,093$10.1M1.45%+7,59313F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.204,790$9.87M0.01%+196,16713F-HRTimelineGroup
TD Asset Management Inc204,762$9.87M0.01%+30,08813F-HRTimeline
STEMPOINT CAPITAL LP200,267$9.65M1.86%-150,80613F-HR/ATimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO212,803$9.35M<0.01%+199,84713F-HR/ATimelineGroup
Woodline Partners LP190,808$9.2M0.03%+66,90613F-HR/ATimeline
ArrowMark Colorado Holdings LLC188,195$9.07M0.24%-83,01813F-HRTimeline
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP181,415$8.74M0.01%+85,87213F-HRTimelineGroup
Cormorant Asset Management, LP175,000$8.44M0.43%new13F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC168,931$8.14M0.01%+16,37113F-HRTimelineGroup
NOMURA ASSET MANAGEMENT CO LTDgroup of 2 filers holding166,805$8.04M+55,008Timeline
Schonfeld Strategic Advisors LLC165,426$7.97M0.06%+156,69913F-HRTimeline
Holocene Advisors, LP159,009$7.66M0.02%new13F-HRTimeline
TCG Crossover Management, LLC140,411$6.77M0.19%-780,44613F-HRTimeline
Eversept Partners, LP138,036$6.65M0.44%+10,47513F-HRTimeline
NEXTBio Capital Management LP133,239$6.42M2.98%+38,79613F-HRTimeline
HSG Holding Ltdin group HSG Holding Ltd266,062$6.2M0.38%013F-HRTimelineGroup
Rhenman & Partners Asset Management AB128,100$6.17M0.76%-19,50013F-HRTimeline
B Group, Inc.127,500$6.15M4.56%+37,50013F-HRTimeline
Davern Capital Partners, LP126,461$6.1M1.67%new13F-HRTimeline
PFM Health Sciences, LP126,383$6.09M0.64%+58,13513F-HRTimeline
HighVista Strategies LLC123,909$5.97M1.65%-69,09213F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 3 filers holding116,359$5.61M-60,346Timeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …114,814$5.53M<0.01%+18,42713F-HRTimelineGroup
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …109,638$5.28M0.01%+26,58613F-HRTimelineGroup
Trexquant Investment LP107,884$5.2M0.04%+17,93913F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC107,857$5.2M0.08%new13F-HRTimelineGroup
Jones Hill Capital LP100,593$4.85M1.04%13F-HRTimeline
Birchview Capital, LP100,000$4.82M2.74%+10,00013F-HRTimeline
PEREGRINE CAPITAL MANAGEMENT LLC97,117$4.68M0.17%+12,79313F-HRTimeline
Soleus Capital Management, L.P.80,000$3.86M0.16%-10,00013F-HRTimeline
TUDOR INVESTMENT CORP ET AL75,301$3.63M0.02%+40,24813F-HRTimeline
Boxer Capital Management, LLCin group Boxer Capital Management, LLC75,000$3.62M0.47%013F-HRTimelineGroup
Qube Research & Technologies Ltd73,599$3.55M0.01%new13F-HRTimeline
DIADEMA PARTNERS LP72,234$3.48M1.44%new13F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP69,107$3.33M<0.01%-99,47713F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC67,862$3.27M<0.01%+12,71413F-HRTimelineGroup
PLATINUM INVESTMENT MANAGEMENT LTD66,864$3.22M0.81%-21,01013F-HRTimeline
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.62,592$3.02M0.04%-40,40113F-HRTimelineGroup
Burkehill Global Management, LP60,000$2.89M0.14%013F-HRTimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC57,667$2.78M0.01%+7,94113F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC55,800$2.69M<0.01%-59,40013F-HRTimeline
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.50,800$2.45M0.42%+9,80013F-HRTimelineGroup
Monashee Investment Management LLC50,000$2.41M1.31%-175,00013F-HRTimeline
SEVEN GRAND MANAGERS, LLC50,000$2.41M0.16%013F-HRTimeline
Buckland Partners Management Co LLC50,000$2.41M1.46%013F-HRTimeline
BANQUE PICTET & CIE SA49,367$2.38M0.03%-10,51413F-HRTimeline
STATE STREET CORPin group STATE STREET CORP47,581$2.29M<0.01%-64313F-HRTimelineGroup
Pier Capital, LLC47,551$2.29M0.38%-1,20613F-HRTimeline
DAFNA Capital Management LLC46,500$2.24M0.51%+9,50013F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…47,266$2.2M0.02%-39,04413F-HRTimelineGroup
ANTIPODES PARTNERS Ltd45,361$2.19M0.04%-93013F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC45,139$2.18M<0.01%+75113F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.44,416$2.14M<0.01%-14,82213F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC44,410$2.14M<0.01%-10,89013F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/39,984$1.93M<0.01%-14,35713F-HRTimelineGroup
Headlands Technologies LLC37,156$1.79M0.2%-6,57313F-HRTimeline
FLAX POND CAPITAL, LLC36,000$1.74M1.4%-12,72113F-HRTimeline
PSquared Asset Management AG35,000$1.69M0.59%new13F-HRTimeline
Mariner, LLCin group Mariner, LLC34,480$1.66M<0.01%-9,67513F-HRTimelineGroup
Private Capital Advisors, Inc.34,389$1.66M0.19%+27,04113F-HRTimeline
TrueMark Investments, LLCin group TrueMark Investments, LLC34,377$1.66M0.32%+48413F-HRTimelineGroup
CAPITAL FUND MANAGEMENT S.A.32,436$1.56M0.01%new13F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd30,921$1.49M0.03%+11,72813F-HRTimelineGroup
Avidity Partners Management LP30,000$1.45M0.29%new13F-HR/ATimeline
Verition Fund Management LLC28,074$1.35M0.01%-50,07513F-HRTimeline
DCF Advisers, LLC27,500$1.33M0.5%-2,50013F-HRTimeline
EXCHANGE TRADED CONCEPTS, LLC25,378$1.22M0.01%-60313F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC22,646$1.09M<0.01%new13F-HRTimelineGroup
Walleye Capital LLCin group Walleye Capital LLC21,360$1.03M0.01%+21,35813F-HR/ATimelineGroup
CenterBook Partners LP21,237$1.02M0.05%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC20,494$988K<0.01%+13,15913F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC19,188$925K<0.01%+11,35513F-HRTimelineGroup
Persistent Asset Partners Ltd18,263$880K0.34%+15,82713F-HRTimeline
TEACHERS RETIREMENT SYSTEM OF THE STATE…17,297$834K0.01%013F-HRTimeline
Aquatic Capital Management LLC14,814$714K0.02%new13F-HRTimeline
SECTORAL ASSET MANAGEMENT INC14,102$711K0.59%-9,77013F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO13,990$674K<0.01%-91313F-HRTimelineGroup
MML INVESTORS SERVICES, LLC13,887$669K<0.01%+6,06213F-HRTimeline
China Universal Asset Management Co., L…13,824$666K0.05%+2,93613F-HRTimeline
GSA CAPITAL PARTNERS LLP13,811$666K0.04%new13F-HRTimeline
WEXFORD CAPITAL LP13,709$661K0.11%-1,12613F-HRTimeline
BRANDYWINE MANAGERS, LLCin group BRANDYWINE MANAGERS, LLC13,357$644K0.38%013F-HRTimelineGroup
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC11,377$548K<0.01%-19313F-HRTimelineGroup
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP11,342$547K<0.01%+6,51213F-HRTimelineGroup
Verdad Advisers, LP11,335$546K0.62%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS10,879$524K<0.01%+2,13313F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…10,701$516K<0.01%-15,57313F-HRTimelineGroup
Quinn Opportunity Partners LLC10,000$482K0.03%-15,00013F-HRTimeline
HighTower Advisors, LLC9,620$464K<0.01%+30013F-HRTimeline
LPL Financial LLC9,260$446K<0.01%+1,15113F-HRTimeline
Gilbert & Cook, Inc.9,193$443K0.06%+3,51113F-HRTimeline
SmartHarvest Portfolios, LLC9,056$436K0.18%013F-HRTimeline
Seven Fleet Capital Management LP9,000$434K0.14%new13F-HR/ATimeline
Cinctive Capital Management LP8,714$420K0.03%new13F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE8,600$415K<0.01%-3,40013F-HRTimelineGroup
DNB Asset Management ASin group DNB Asset Management AS8,188$395K<0.01%-4,45113F-HRTimelineGroup
AXQ CAPITAL, LP7,916$382K0.05%new13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN7,818$377K<0.01%+2,15413F-HR/ATimelineGroup
Cetera Investment Advisers7,720$372K<0.01%+1,12413F-HRTimeline
MISSION WEALTH MANAGEMENT, LP7,583$366K0.01%-2,00013F-HRTimeline
Vestmark Advisory Solutions, Inc.7,534$363K<0.01%013F-HRTimeline
Independent Advisor Alliance7,444$359K<0.01%+2,90113F-HRTimeline
Parallel Advisors, LLC7,352$354K0.01%013F-HR/ATimeline
Scientech Research LLC6,958$335K0.28%new13F-HRTimeline
Janney Montgomery Scott LLC6,819$329K<0.01%new13F-HRTimeline
Bellevue Group AGin group Bellevue Group AG6,803$328K0.01%-138,36413F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…6,411$309K<0.01%+1,14413F-HR/ATimelineGroup
PEAK6 LLCin group PEAK6 LLC6,055$292K0.01%-1,90013F-HRTimelineGroup
Advisory Services Network, LLC5,879$283K<0.01%new13F-HRTimeline
Jain Global LLC5,772$278K<0.01%-94,22413F-HRTimeline
Concurrent Investment Advisors, LLCin group Concurrent Investment Advisor…5,000$241K<0.01%013F-HRTimelineGroup
Quadcap Wealth Management, LLC4,729$228K0.03%-2,75413F-HRTimeline
Tidal Investments LLCin group Tidal Investments LLC4,643$224K<0.01%new13F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.4,581$221K<0.01%+1,38113F-HRTimelineGroup
E. Ohman J:or Asset Management AB4,518$218K0.01%013F-HRTimeline
Arrowpoint Investment Partners (Singapo…in group Arrowpoint Investment Partner…4,190$202K0.29%new13F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…4,065$196K0.05%+9813F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…2,854$138K<0.01%-1,07213F-HRTimelineGroup
SG Americas Securities, LLC2,649$128K<0.01%-7,49813F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC2,544$123K<0.01%+44913F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…2,220$107K<0.01%+1,48913F-HRTimelineGroup
Penserra Capital Management LLCin group Penserra Capital Management L…1,738$83K<0.01%new13F-HRTimelineGroup
NANO CAP NEW MILLENNIUM GROWTH FUND L P1,500$72.3K0.07%new13F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,500$72.3K<0.01%+18813F-HRTimeline
Steward Partners Investment Advisory, L…1,400$67.5K<0.01%-1,14013F-HRTimeline
GAMMA Investing LLC999$48.2K<0.01%+6913F-HRTimeline
Farther Finance Advisors, LLC931$46.7K<0.01%+24113F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA722$35K<0.01%-9,47813F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…646$31.1K<0.01%+60513F-HRTimelineGroup
Sterling Capital Management LLC590$28.4K<0.01%new13F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…558$26.9K<0.01%-2013F-HR/ATimelineGroup
State of Wyoming433$20.9K<0.01%-1,32813F-HRTimeline
WOLFF WIESE MAGANA LLC400$19.3K0.01%013F-HRTimeline
North Star Investment Management Corp.330$15.9K<0.01%013F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP341$15.7K<0.01%-70513F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…212$10.2K<0.01%new13F-HRTimeline
SOA Wealth Advisors, LLC.200$9.64K<0.01%-15013F-HRTimeline
Dynamic Wealth Strategies, LLC150$7.23K<0.01%013F-HRTimeline
CWM, LLCin group CWM, LLC125$6.03K<0.01%-35513F-HRTimelineGroup
FARMERS & MERCHANTS INVESTMENTS INCin group FARMERS & MERCHANTS INVESTMEN…100$4.82K<0.01%new13F-HRTimelineGroup
SIGNATUREFD, LLC100$4.82K<0.01%-6,55013F-HRTimeline
Key Financial Inc100$4.82K<0.01%new13F-HRTimeline
SHP Wealth Management100$4.82K<0.01%013F-HRTimeline
Basecamp Wealth Advisors LLC84$4.05K<0.01%new13F-HRTimeline
Rakuten Securities, Inc.in group Rakuten Group, Inc.60$2.89K<0.01%new13F-HRTimelineGroup
Transamerica Financial Advisors, LLCin group Transamerica Financial Adviso…22$1.06K<0.01%new13F-HRTimelineGroup
Capital Analysts, LLCin group Capital Analysts, LLC18$1K<0.01%013F-HRTimelineGroup
Smartleaf Asset Management LLC17$747<0.01%new13F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\10$482<0.01%new13F-HRTimelineGroup
Ancora Advisors LLCin group Ancora Advisors LLC10$482<0.01%013F-HRTimelineGroup
Allworth Financial LP9$434<0.01%new13F-HRTimeline
Cullen/Frost Bankers, Inc.in group Cullen/Frost Bankers, Inc.8$386<0.01%013F-HRTimelineGroup
Larson Financial Group LLC5$241<0.01%013F-HRTimeline
HUNTINGTON NATIONAL BANKin group HUNTINGTON NATIONAL BANK2$96<0.01%013F-HRTimelineGroup
IMA Advisory Services, Inc.2$96<0.01%new13F-HRTimeline