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Disclosery

GPCR STRUCTURE THERAPEUTICS INC

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EQUITY (ADR), issuer CIK 1888886

149 managers (151 13F filers) reported a position in GPCR shares at 2025-03-31, 55,933,663 shares in all. 23 filers opened a position and 36 filers sold out during the quarter.

Managers
149
13F filers
151
New
23
Added
46
Reduced
50
Sold out
36
Shares held by filers
55,933,663

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2025

Filers in the available 13F reports with a share position at 2025-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…7,791,183$135M0.03%+5,56913F-HRTimelineGroup
FMR LLCin group FMR LLC5,883,707$102M0.01%-195,03913F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson4,355,194$86.1M0.05%+195,30613F-HRTimelineGroup
Deep Track Capital, LP4,100,000$71M2.3%+1,300,00013F-HRTimeline
Capital Research Global Investorsin group Capital Research Global Inves…2,164,145$37.5M0.01%-1,373,19613F-HRTimelineGroup
Vestal Point Capital, LP1,788,990$31M2.21%+63,99013F-HRTimeline
BVF INC/ILin group BVF INC/IL1,771,417$30.7M1.25%013F-HRTimelineGroup
Capital International Investorsin group Capital International Investo…1,619,026$28M0.01%-5513F-HRTimelineGroup
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.1,517,418$26.3M0.44%013F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC1,481,809$25.7M0.01%+61,75713F-HRTimelineGroup
Driehaus Capital Management LLC1,272,743$22M0.21%-784,66713F-HRTimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.1,170,948$20.3M0.04%-875,01013F-HRTimelineGroup
FIL Ltdin group FIL Ltd1,150,440$19.9M0.02%-149,57513F-HRTimelineGroup
Rock Springs Capital Management LP1,132,979$19.6M1.12%+52,01613F-HRTimeline
TCG Crossover Management, LLC1,063,000$18.4M2.51%013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC992,340$17.2M0.02%-486,99913F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC790,159$13.7M0.01%+39,14613F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/777,173$13.5M<0.01%-617,13313F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC756,707$13.1M0.01%-34,42713F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources740,152$12.8M<0.01%+2,06213F-HRTimelineGroup
Catalio Capital Management, LP704,864$12.2M3.02%+135,46913F-HRTimeline
Casdin Capital, LLC700,000$12.1M0.99%013F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY692,439$12M<0.01%+305,26313F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC652,028$11.3M0.27%013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.566,505$9.81M<0.01%-44,08013F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC510,201$8.83M0.01%-102,41513F-HRTimelineGroup
READYSTATE ASSET MANAGEMENT LP481,241$8.33M0.42%+271,89913F-HRTimeline
Logos Global Management LP425,000$7.36M1.31%-275,00013F-HRTimeline
Foresite Capital Management VI LLCin group Foresite Capital Management V…420,000$7.27M3.98%013F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.394,386$6.83M<0.01%+22,61913F-HRTimelineGroup
Handelsbanken Fonder AB380,000$6.58M0.03%+215,00013F-HRTimeline
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…373,407$6.46M0.13%013F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP361,565$6.26M0.07%013F-HRTimelineGroup
HSG Holding Ltdin group HSG Holding Ltd266,062$6.2M0.36%013F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC324,435$5.62M<0.01%-258,43013F-HR/ATimelineGroup
Camber Capital Management LP300,000$5.19M0.32%013F-HRTimeline
Monashee Investment Management LLC292,862$5.07M0.6%+160,86213F-HRTimeline
Ikarian Capital, LLCin group Ikarian Capital, LLC264,085$4.57M1.49%-20,00013F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc248,899$4.31M0.01%+77,51113F-HRTimelineGroup
ArrowMark Colorado Holdings LLC245,186$4.24M0.07%+12,27713F-HRTimeline
UBS Group AGgroup of 2 filers holding244,112$4.23M+49Timeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.229,431$3.97M0.01%-247,26713F-HR/ATimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding226,128$3.91M+157,925Timeline
Bellevue Group AGin group Bellevue Group AG221,715$3.84M0.09%-263,33513F-HRTimelineGroup
Candriam S.C.A.214,063$3.71M0.02%-1,35813F-HRTimeline
Pier Capital, LLC212,520$3.68M0.62%+79,91613F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management202,483$3.5M0.01%new13F-HRTimelineGroup
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…188,069$3.26M0.68%+35,67413F-HRTimelineGroup
Woodline Partners LP175,424$3.04M0.02%-158,47713F-HRTimeline
Nantahala Capital Management, LLCin group Nantahala Capital Management,…168,553$2.92M0.24%-52,44713F-HRTimelineGroup
CCG WEALTH MANAGEMENT, LLC150,000$2.6M1.55%013F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO134,239$2.32M<0.01%+101,92413F-HRTimelineGroup
First Light Asset Management, LLC132,380$2.29M0.26%-266,47513F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC120,703$2.09M<0.01%+4,69013F-HR/ATimelineGroup
Trexquant Investment LP120,340$2.08M0.02%+67,46413F-HRTimeline
CITIGROUP INCin group CITIGROUP INC104,975$1.82M<0.01%+30,89113F-HRTimelineGroup
Exome Asset Management LLC102,944$1.78M1.6%-49,02113F-HR/ATimeline
Zimmer Partners, LP100,776$1.74M0.04%+43,87613F-HRTimeline
Point72 Europe (London) LLP90,697$1.57M0.11%+59,27713F-HRTimeline
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.84,000$1.45M0.36%new13F-HRTimelineGroup
BANQUE PICTET & CIE SA81,766$1.42M0.02%+7,58913F-HRTimeline
CAPITAL FUND MANAGEMENT S.A.79,656$1.38M0.02%+12,52113F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC77,294$1.34M0.05%-5,85413F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …76,863$1.33M<0.01%-37,12913F-HRTimelineGroup
PLATINUM INVESTMENT MANAGEMENT LTD74,900$1.3M0.08%013F-HRTimeline
Rhenman & Partners Asset Management AB70,000$1.21M0.14%new13F-HRTimeline
DAFNA Capital Management LLC59,000$1.02M0.29%+23,50013F-HRTimeline
MACQUARIE GROUP LTDin group MACQUARIE GROUP LTD58,000$1M<0.01%013F-HR/ATimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/55,438$960K<0.01%+1,25313F-HRTimelineGroup
Cubist Systematic Strategies, LLC54,816$949K0.01%new13F-HRTimeline
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/53,235$921K<0.01%+3,06213F-HRTimelineGroup
GROUP ONE TRADING LLC48,917$847K0.04%+27,35013F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC45,737$792K<0.01%+3213F-HRTimelineGroup
TD Asset Management Inc43,686$756K<0.01%-45,19613F-HRTimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC43,080$746K<0.01%-3,22013F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …40,737$705K<0.01%-17,50513F-HRTimelineGroup
PFM Health Sciences, LP40,400$699K0.05%new13F-HRTimeline
TrueMark Investments, LLCin group TrueMark Investments, LLC39,217$679K0.18%-2,91013F-HRTimelineGroup
EXCHANGE TRADED CONCEPTS, LLC38,923$674K0.01%-1,51213F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC35,619$617K0.12%+30013F-HRTimelineGroup
Sofinnova Investments, Inc.34,952$605K0.05%+14,06013F-HRTimeline
SECTORAL ASSET MANAGEMENT INC33,695$583K0.45%-15,55513F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.31,390$543K<0.01%+59813F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC30,710$532K0.01%new13F-HR/ATimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP30,626$530K<0.01%-552,58113F-HRTimelineGroup
WEXFORD CAPITAL LP30,102$521K0.14%-51,77013F-HRTimeline
NOMURA ASSET MANAGEMENT CO LTDin group NOMURA ASSET MANAGEMENT CO LTD28,974$502K<0.01%-7,95113F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC25,940$449K<0.01%013F-HR/ATimelineGroup
PRELUDE CAPITAL MANAGEMENT, LLC25,628$444K0.04%-6,37213F-HRTimeline
Jain Global LLC23,639$409K0.01%new13F-HRTimeline
HRT FINANCIAL LP22,859$395K<0.01%new13F-HRTimeline
NEOS Investment Management LLC22,590$391K0.01%-21,75313F-HRTimeline
Tema ETFs LLC22,590$391K0.12%-21,75313F-HRTimeline
Quinn Opportunity Partners LLC22,000$381K0.03%+10,00013F-HRTimeline
SIMPLEX TRADING, LLC20,604$356K0.01%+3,25813F-HRTimeline
Verition Fund Management LLC19,582$339K<0.01%new13F-HRTimeline
Mariner, LLCin group Mariner, LLC18,051$312K<0.01%-6,47913F-HRTimelineGroup
TEACHERS RETIREMENT SYSTEM OF THE STATE…17,651$306K<0.01%013F-HRTimeline
HighVista Strategies LLC17,561$304K0.12%013F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC15,800$273K<0.01%new13F-HRTimeline
Quantbot Technologies LP14,401$249K0.01%new13F-HRTimeline
Good Life Advisors, LLC13,000$225K0.02%new13F-HRTimeline
China Universal Asset Management Co., L…11,951$207K0.02%-68313F-HRTimeline
Graham Capital Management, L.P.11,908$206K0.01%new13F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.11,661$202K<0.01%new13F-HRTimelineGroup
BRANDYWINE MANAGERS, LLCin group BRANDYWINE MANAGERS, LLC11,057$191K0.23%013F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP10,740$186K<0.01%+21313F-HRTimelineGroup
Bleichroeder LP10,000$173K0.05%013F-HRTimeline
PEAK6 LLCin group PEAK6 LLC9,445$163K0.01%013F-HRTimelineGroup
Caption Management, LLC9,256$160K0.01%+3,65613F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN7,345$127K<0.01%-2,75813F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC5,312$92K<0.01%-110,35913F-HR/ATimelineGroup
Virtus Investment Advisers, LLCgroup of 2 filers holding5,177$89.6K+2,935Timeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS4,518$78.2K<0.01%-6,70013F-HRTimelineGroup
ANTIPODES PARTNERS Ltd4,247$73.5K<0.01%+3,21313F-HRTimeline
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…3,685$72.9K<0.01%+11913F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA3,711$64K<0.01%-121,98113F-HR/ATimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP3,146$62.2K<0.01%-1,08213F-HR/ATimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…3,421$59.2K<0.01%+14413F-HRTimelineGroup
Penserra Capital Management LLCin group Penserra Capital Management L…3,411$59K<0.01%+30413F-HRTimelineGroup
Headlands Technologies LLC3,408$59K0.01%-75213F-HRTimeline
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/2,957$51.1K<0.01%+2,76613F-HRTimelineGroup
Steward Partners Investment Advisory, L…2,516$43.6K<0.01%+40213F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC2,057$35.6K<0.01%-21413F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.1,525$26.4K<0.01%+27413F-HRTimeline
FNY Investment Advisers, LLC1,200$20K0.01%-30013F-HRTimeline
SVB WEALTH LLC836$14.5K<0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…595$10.3K<0.01%-3,48113F-HRTimelineGroup
GAMMA Investing LLC507$8.78K<0.01%-64213F-HR/ATimeline
RHUMBLINE ADVISERS450$7.79K<0.01%013F-HR/ATimeline
Caitong International Asset Management …376$6.51K<0.01%+19013F-HRTimeline
North Star Investment Management Corp.330$5.71K<0.01%013F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.226$4K<0.01%013F-HRTimelineGroup
Private Wealth Management Group, LLC196$3.39K<0.01%new13F-HRTimeline
WOLFF WIESE MAGANA LLC134$2.32K<0.01%new13F-HRTimeline
CWM, LLCin group CWM, LLC100$2K<0.01%013F-HRTimelineGroup
SIGNATUREFD, LLC100$1.73K<0.01%013F-HRTimeline
CoreCap Advisors, LLC77$1.33K<0.01%013F-HRTimeline
Clearstead Advisors, LLC67$1.16K<0.01%013F-HRTimeline
Washington Trust Advisors, Inc.41$710<0.01%013F-HRTimeline
MATHER GROUP, LLC.35$606<0.01%new13F-HRTimeline
Federation des caisses Desjardins du Qu…20$346<0.01%013F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\13$225<0.01%-8813F-HRTimelineGroup
MAI Capital Management10$174<0.01%new13F-HRTimeline
Larson Financial Group LLC9$156<0.01%new13F-HRTimeline
Cullen/Frost Bankers, Inc.in group Cullen/Frost Bankers, Inc.8$138<0.01%013F-HRTimelineGroup
HUNTINGTON NATIONAL BANKin group HUNTINGTON NATIONAL BANK2$35<0.01%013F-HRTimelineGroup
Point72 Asia (Singapore) Pte. Ltd.1$17<0.01%013F-HRTimeline
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.