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TWO SIGMA INVESTMENTS, LP: GPCR position timeline

Available 13F reports, 13D and 13G stakes and each Form 3, 4 and 5 line of TWO SIGMA INVESTMENTS, LP on GPCR, newest first. How the timeline and the estimate are built.

TWO SIGMA INVESTMENTS, LP held 204,156 GPCR shares at 2026-06-30 per its 13F-HR filed 2026-08-14.

the latest 13F is the newest step

  1. period ended2026-06-30
    13F 204,156 shares
    Change vs previous 13F +22,741 shares

    0.01% of the 13F portfolio, value $10,957,053.

    13F-HR 0000899140-26-000855 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  2. period ended2026-03-31
    13F 181,415 shares
    Share basis changed not comparable

    Membership change: TWO SIGMA ADVISERS, LP left the group. 0.01% of the 13F portfolio, value $8,744,203.

    13F-HR 0000899140-26-000547 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  3. period ended2025-12-31
    13F 95,543 shares
    Change vs previous 13F -336,667 shares

    0.01% of the 13F portfolio, value $6,645,016.

    13F-HR 0000899140-26-000232 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 95,543 shares
    • TWO SIGMA ADVISERS, LP: 0 shares

    Acceptance time not in the bulk data set (spec §4.2).

  4. period ended2025-09-30
    13F 432,210 shares
    Change vs previous 13F +396,110 shares

    0.01% of the 13F portfolio, value $12,101,880.

    13F-HR 0000899140-25-001279 filed by TWO SIGMA ADVISERS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 182,911 shares
    • TWO SIGMA ADVISERS, LP: 249,299 shares

    Acceptance time not in the bulk data set (spec §4.2).

  5. period ended2025-06-30
    13F 36,100 shares
    Change vs previous 13F not available

    <0.01% of the 13F portfolio, value $748,714.

    13F-HR 0000899140-25-000953 filed by TWO SIGMA ADVISERS, LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).