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Disclosery

Siren, L.L.C.: GPCR position timeline

Available 13F reports, 13D and 13G stakes and each Form 3, 4 and 5 line of Siren, L.L.C. on GPCR, newest first. How the timeline and the estimate are built.

Siren, L.L.C. held 872,967 GPCR shares at 2026-06-30 per its 13F-HR filed 2026-08-13.

the latest 13F is the newest step

  1. period ended2026-06-30
    13F 872,967 shares
    Change vs previous 13F -455,731 shares

    0.95% of the 13F portfolio, value $46,852,139.

    13F-HR 0002005245-26-000008 filed by Siren, L.L.C.
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  2. period ended2026-03-31
    13F 1,328,698 shares
    Change vs previous 13F +250,000 shares

    1.78% of the 13F portfolio, value $64,043,244.

    13F-HR 0002005245-26-000006 filed by Siren, L.L.C.
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  3. period ended2025-12-31
    13F 1,078,698 shares
    Change vs previous 13F +51,887 shares

    2.24% of the 13F portfolio, value $75,023,446.

    13F-HR 0002005245-26-000003 filed by Siren, L.L.C.
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  4. period ended2025-09-30
    13F 1,026,811 shares
    Change vs previous 13F not available

    1.12% of the 13F portfolio, value $28,750,708.

    13F-HR 0002005245-25-000012 filed by Siren, L.L.C.
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).