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Disclosery

13F-HR filed by DAFNA Capital Management LLC

DAFNA Capital Management LLC filed this 13F-HR for the quarter ended 2026-06-30, filed 2026-08-14, with 88 holding rows worth $524,358,409.

Accession
0001389933-26-000006
Filer
CIK 1389933
Filed
2026-08-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q2 2026

A holdings report, 88 entries on the cover page, a total value of $524,358,409 stated on the cover page (in dollars after the unit check, H1), rows summing to $524,358,409 with VALUE read as dollars as filed, 13F file number 028-12327. The quarter's positions are built on this report. The resolved quarter.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
REVOLUTION MEDICINES INC COM76155X100Stock562,630$105,369,346dollars as filed
SPDR SER TR78464A870S&P BIOTECH196,505$31,096,916dollars as filed
COMPASS PATHWAYS PLC20451W101SPONSORED ADS2,011,952$28,469,121dollars as filed
STEREOTAXIS INC85916J409COMMON STOCK13,680,554$23,530,553dollars as filed
NEKTAR THERAPEUTICS640268306COMMON STOCK318,380$22,226,108dollars as filed
DENALI THERAPEUTICS INC COM24823R105Stock739,014$19,007,440dollars as filed
IDEAYA BIOSCIENCES INC COM45166A102Stock497,240$18,532,135dollars as filed
ATRICURE INC04963C209COM597,431$16,716,119dollars as filed
XENON PHARMACEUTICALS INC COM98420N105Stock250,772$15,136,598dollars as filed
CYTOKINETICS INC23282W605COM NEW171,998$14,652,510dollars as filed
ARCUS BIOSCIENCES INC03969F109COM441,829$13,621,588dollars as filed
ASCENDIS PHARMA A/SK08588103ORD SHS *A*48,469$12,927,652dollars as filed
NEUROCRINE BIOSCIENCES INC64125C109COM57,769$9,736,098dollars as filed
AXOGEN INC05463X106COM208,960$9,651,862dollars as filed
INSULET CORP COM45784P101Stock61,870$9,419,708dollars as filed
EDGEWISE THERAPEUTICS INC28036F105COM226,819$9,215,656dollars as filed
BICARA THERAPEUTICS INC055477103COM284,955$8,460,314dollars as filed
ISHARES TR464287556ISHARES BIOTECH42,595$8,101,143dollars as filed
SYNDAX PHARMACEUTICALS INC87164F105COM335,255$7,328,674dollars as filed
MAPLIGHT THERAPEUTICS INC56565P103COMMON STOCK171,006$6,128,855dollars as filed
LARIMAR THERAPEUTICS INC517125100COM2,008,164$6,124,900dollars as filed
CENTURY THERAPEUTICS INC15673T100COM2,400,458$5,881,122dollars as filed
DEXCOM INC COM252131107Stock86,279$5,810,891dollars as filed
IMMUNOVANT INC45258J102COM149,524$5,761,160dollars as filed
INOGEN INC45780L104COM845,179$5,451,405dollars as filed
TANDEM DIABETES CARE INC875372203COM NEW355,208$5,360,089dollars as filed
ALKERMES PLCG01767105SHS101,266$5,305,832dollars as filed
STOKE THERAPEUTICS INC86150R107COM130,875$4,282,230dollars as filed
ALLOGENE THERAPEUTICS INC019770106COM2,000,000$4,160,000dollars as filed
BIOCRYST PHARMACEUTICALS INC COM09058V103Stock400,248$4,002,480dollars as filed
LAKEFRONT BIOTHERAPEUTICS NV36315X101SPON ADR130,175$3,902,647dollars as filed
ORTHOPEDIATRICS CORP68752L100COMMON STOCK189,130$3,618,057dollars as filed
CYBIN INC23256X407COM NEW514,061$3,397,943dollars as filed
RAPPORT THERAPEUTICS INC COM75383L102Stock75,000$3,125,250dollars as filed
KYMERA THERAPEUTICS INC501575104COM27,000$3,096,090dollars as filed
PROQR THERAPEUTICS NVN71542109SHS EURO1,530,361$2,846,471dollars as filed
NEUROGENE INC64135M105COMMON STOCK89,032$2,800,056dollars as filed
Adlai Nortye00704R109SPONSORED ADS239,553$2,754,860dollars as filed
PROCEPT BIOROBOTICS CORP COM74276L105Stock120,000$2,709,600dollars as filed
AQUESTIVE THERAPEUTICS INC COM03843E104Stock645,915$2,687,006dollars as filed
CELLDEX THERAPEUTICS INC NEW15117B202COM NEW68,518$2,549,555dollars as filed
STRUCTURE THERAPEUTICS INC COMP86366E106EQUITY46,500$2,495,655dollars as filed
ALIGN TECHNOLOGY INC COM016255101Stock14,000$2,361,240dollars as filed
VIKING THERAPEUTICS INC92686J106COM59,516$2,321,719dollars as filed
NERVGEN PHARMA CORP64082X203COM1,050,000$2,163,000dollars as filed
BIOHAVEN LTDG1110E107COM137,593$2,047,384dollars as filed
MAZE THERAPEUTICS INC COM578784100Stock65,000$1,939,600dollars as filed
ALECTOR INC014442107COMMON STOCK908,351$1,825,786dollars as filed
LEXEO THERAPEUTICS INC52886X107COMMON STOCK377,059$1,755,210dollars as filed
PROFOUND MED CORP74319B502COM NEW260,360$1,731,394dollars as filed
ATRIUM THERAPEUTICS INC COM04965N104Stock128,000$1,721,600dollars as filed
ANNEXON INC03589W102COM297,812$1,700,507dollars as filed
CYTOMX THERAPEUTICS INC23284F105COMMON STOCK438,407$1,644,026dollars as filed
ULTRAGENYX PHARMACEUTICAL IN90400D108COM47,100$1,572,669dollars as filed
EUPRAXIA PHARMACEUTICALS INC29842P105COM 298736 AL 3 EURONET WORLDWIDE INC NOTE 0.750% 3/1225,600$1,491,216dollars as filed
DESIGN THERAPEUTICS INC25056L103COM102,600$1,484,622dollars as filed
FATE THERAPEUTICS INC31189P102COM525,000$1,417,500dollars as filed
MEDIWOUND LTDM68830112COMMON STOCK94,405$1,387,754dollars as filed
KURA ONCOLOGY INC COM50127T109Stock120,568$1,322,631dollars as filed
ARS PHARMACEUTICALS INC82835W108COM164,285$1,315,923dollars as filed
MINERALYS THERAPEUTICS INC603170101COM44,490$1,200,340dollars as filed
IMMATICS N.VN44445109SHS116,960$1,184,805dollars as filed
TELA BIO INC872381108COM1,441,029$1,080,772dollars as filed
POLYPID LTDM8001Q126COM207,900$1,056,132dollars as filed
CORBUS PHARMACEUTICALS21833P301COM NEW107,773$1,010,911dollars as filed
INSPIRE MED SYS INC COM457730109Stock18,200$811,902dollars as filed
ADICET BIO INC007002207COM NEW93,812$810,536dollars as filed
SEAPORT THERAPEUTICS INC81221K108COMMON STOCK32,400$703,728dollars as filed
MBX BIOSCIENCES INC COM55287L101Stock11,809$651,857dollars as filed
BIONTECH SE SPONSORED ADS09075V102ADR7,000$651,350dollars as filed
ARTIVA BIOTHERAPEUTICS INC04317A107COM67,101$650,880dollars as filed
PLIANT THERAPEUTICS INC729139105COM487,000$555,180dollars as filed
SCYNEXIS INC811292309COM135,868$552,983dollars as filed
EDITAS MEDICINE INC28106W103COM170,470$552,323dollars as filed
ORCHESTRA BIOMED HOLDINGS IN68572M106COMMON STOCK126,841$547,319dollars as filed
FOGHORN THERAPEUTICS INC344174107COMMON STOCK111,859$545,872dollars as filed
ACCURAY INC DEL004397105COM1,680,508$433,235dollars as filed
Q32 BIO INC746964105Common Stock32,896$419,095dollars as filed
NUVECTIS PHARMA INC67080T108COMMON STOCK20,000$367,800dollars as filed
COMPUGEN LTDM25722105ORD168,232$360,016dollars as filed
IBIO INC451033708CMN170,053$297,593dollars as filed
AUTOLUS THERAPEUTICS PLC SPON05280R100COM179,316$286,906dollars as filed
BICYCLE THERAPEUTICS PLC-ADR088786108SPONSORED ADS64,492$273,446dollars as filed
TENAYA THERAPEUTICS INC87990A106COM300,000$221,730dollars as filed
VERRICA PHARMACEUTICALS INC92511W207COM SHS23,750$145,350dollars as filed
ENGENE THERAPEUTICS INC29286X101COM74,650$129,145dollars as filed
KARDIGAN INC485925101CMN5,000$119,250dollars as filed
ADC THERAPEUTICS SAH0036K147COMMON STOCK77,081$82,477dollars as filed

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001389933-26-000006this filing2026-08-14acceptance time not in the bulk data set