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Disclosery

SVRA SAVARA INC

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COM (common), issuer CIK 1160308

144 managers (148 13F filers) reported a position in SVRA shares at 2025-12-31, 201,147,205 shares in all. 38 filers opened a position and 13 filers sold out during the quarter.

Managers
144
13F filers
148
New
38
Added
53
Reduced
40
Sold out
13
Shares held by filers
201,147,205

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
NEA Management Company, LLC24,471,264$148M7.52%013F-HRTimeline
Bain Capital Life Sciences Investors, L…in group Bain Capital Life Sciences In…17,600,621$106M8.13%013F-HRTimelineGroup
Venrock Adviser, LLC13,740,375$82.9M4.09%+1,059,33213F-HRTimeline
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…13,569,000$81.8M1.05%+5,605,00013F-HRTimelineGroup
TCG Crossover Management, LLC12,362,205$74.5M2.47%013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.11,097,289$66.9M<0.01%+2,649,04913F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC10,041,647$60.6M<0.01%+1,728,45313F-HRTimelineGroup
Frazier Life Sciences Management, L.P.9,862,301$59.5M1.6%-1,600,00013F-HRTimeline
Polar Capital Holdings Plcin group Polar Capital Holdings Plc8,306,196$50.1M0.23%new13F-HRTimelineGroup
Nantahala Capital Management, LLCin group Nantahala Capital Management,…7,344,783$44.3M2.64%-1,430,59213F-HRTimelineGroup
RTW INVESTMENTS, LP5,952,380$35.9M0.36%new13F-HRTimeline
EMERALD ADVISERS, LLCgroup of 2 filers holding5,891,954$35.5M+211,272Timeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP4,559,921$27.5M0.03%new13F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP4,333,022$26.1M<0.01%+1,973,16413F-HRTimelineGroup
Woodline Partners LP4,244,640$25.6M0.1%+4,007,41913F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC3,417,769$20.6M<0.01%+622,10813F-HRTimelineGroup
Rosalind Advisors, Inc.3,403,721$20.5M7.48%-596,27913F-HRTimeline
Affinity Asset Advisors, LLC2,797,153$16.9M1.21%+1,297,15313F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…2,674,931$16.1M<0.01%+30,93113F-HRTimelineGroup
Spruce Street Capital LP2,411,093$14.5M4.8%13F-HRTimeline
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC2,400,000$14.5M0.27%new13F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY2,337,896$14.1M<0.01%+420,06913F-HR/ATimelineGroup
NAN FUNG TRINITY (HK) LTD1,688,500$10.2M0.81%new13F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.1,669,370$10.1M0.01%+1,297,34513F-HRTimelineGroup
Vestal Point Capital, LP1,606,000$9.68M0.36%-2,409,00013F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC1,405,452$8.47M0.63%-582,83613F-HR/ATimelineGroup
Longaeva Partners L.P.1,246,042$7.51M0.89%new13F-HRTimeline
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.1,178,164$7.1M1.48%-172,16913F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co1,161,672$7M<0.01%+197,87413F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP1,077,625$6.5M<0.01%+130,89313F-HRTimelineGroup
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …1,061,198$6.4M0.01%new13F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.1,000,000$6.03M0.18%new13F-HRTimelineGroup
SUPERSTRING CAPITAL MANAGEMENT LP995,353$6M3.21%-313,88313F-HRTimeline
Swedbank ABin group Swedbank AB850,000$5.13M<0.01%+300,00013F-HR/ATimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\824,717$4.97M<0.01%-26,26113F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC774,492$4.67M<0.01%+106,38613F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC751,255$4.53M<0.01%-105,34513F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.688,595$4.15M<0.01%+517,32913F-HRTimelineGroup
F/m Investments LLC678,813$4.09M0.16%+245,10013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 3 filers holding663,862$4M+542,022Timeline
Sio Capital Management, LLC613,888$3.7M0.61%-112,96313F-HRTimeline
KVP Capital Advisors, LP605,280$3.65M3.77%13F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC584,289$3.52M<0.01%-21,27613F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC534,968$3.23M<0.01%-309,20913F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC516,598$3.12M<0.01%-145,64813F-HR/ATimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/423,596$2.55M<0.01%+303,60713F-HRTimelineGroup
SummitTX Capital, L.P.373,034$2.25M0.07%new13F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC332,100$2M<0.01%+72,00013F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp312,870$1.89M<0.01%+39,51413F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC306,940$1.85M<0.01%+130,42413F-HRTimelineGroup
Sofinnova Investments, Inc.304,770$1.84M0.08%-2,122,95413F-HRTimeline
Nuveen, LLCin group TIAA272,602$1.64M<0.01%+35,76713F-HRTimelineGroup
UBS Group AGin group UBS Group AG202,883$1.22M<0.01%-492,85113F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management188,214$1.13M<0.01%new13F-HRTimelineGroup
Eversept Partners, LP170,195$1.03M0.06%new13F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP170,129$1.03M<0.01%-530,51713F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN167,644$1.01M<0.01%+83,55413F-HRTimelineGroup
RHUMBLINE ADVISERS152,775$921K<0.01%-4,79213F-HRTimeline
Walleye Capital LLCin group Walleye Capital LLC150,084$905K0.01%+59,06313F-HRTimelineGroup
GSA CAPITAL PARTNERS LLP140,753$849K0.07%-231,69613F-HRTimeline
ALLIANCEBERNSTEIN L.P.127,040$766K<0.01%+8,25013F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …90,000$550K<0.01%-20,00013F-HRTimelineGroup
Rafferty Asset Management, LLC89,858$542K<0.01%new13F-HRTimeline
VOLORIDGE INVESTMENT MANAGEMENT, LLC86,160$520K<0.01%new13F-HRTimeline
Cresset Asset Management, LLC83,334$503K<0.01%new13F-HRTimeline
Aquatic Capital Management LLC83,089$501K0.01%new13F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding80,901$488K+21,024Timeline
MetLife Investment Management, LLCin group MetLife Investment Management…78,551$474K<0.01%+18,24513F-HRTimelineGroup
Connor, Clark & Lunn Investment Managem…74,882$452K<0.01%-18,98513F-HRTimeline
OXFORD ASSET MANAGEMENT LLP74,115$447K0.16%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO73,059$441K<0.01%+9,22413F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC70,695$426K0.01%new13F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/69,536$420K<0.01%+2,11613F-HRTimeline
Virtu Financial LLCin group Virtu Financial LLC65,615$396K0.02%new13F-HRTimelineGroup
Seven Fleet Capital Management LP62,762$378K0.26%13F-HR/ATimeline
Graham Capital Management, L.P.56,013$338K0.01%+2,61513F-HRTimeline
Creative Planningin group Creative Planning55,719$336K<0.01%+11,49413F-HRTimelineGroup
BANK OF NOVA SCOTIAin group BANK OF NOVA SCOTIA51,700$312K<0.01%new13F-HRTimelineGroup
Sivia Capital Partners, LLC48,507$292K0.06%+713F-HRTimeline
DYMON ASIA CAPITAL (SINGAPORE) PTE. LTD.in group DYMON ASIA CAPITAL (SINGAPORE…46,000$277K0.06%new13F-HRTimelineGroup
SG Americas Securities, LLC45,526$275K<0.01%new13F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …43,547$263K<0.01%+5,08013F-HRTimelineGroup
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…41,652$251K<0.01%+8,45913F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC40,958$247K<0.01%-5,34513F-HRTimeline
EntryPoint Capital, LLC40,716$246K0.1%-40,93213F-HRTimeline
Caitong International Asset Management …39,649$239K0.06%+37,65413F-HR/ATimeline
Brooklyn Investment Group36,809$233K0.01%-61,83313F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…38,443$232K0.06%-11,90613F-HRTimelineGroup
Jain Global LLC37,705$227K<0.01%-1,80013F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND36,555$220K<0.01%+22,70013F-HRTimeline
PROFUND ADVISORS LLC35,145$212K0.01%new13F-HRTimeline
ProShare Advisors LLC34,869$210K<0.01%+9,13313F-HRTimeline
Police & Firemen's Retirement System of…33,925$205K<0.01%013F-HRTimeline
China Universal Asset Management Co., L…33,155$200K0.02%+2,85913F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.32,678$197K<0.01%+2,09813F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS31,204$188K<0.01%+6,05013F-HRTimelineGroup
FMR LLCin group FMR LLC27,849$168K<0.01%+20,64713F-HRTimelineGroup
Farther Finance Advisors, LLC26,896$162K<0.01%-2,28013F-HRTimeline
STRS OHIO26,500$160K<0.01%new13F-HRTimeline
Focus Partners Wealthin group Focus Partners Wealth25,214$152K<0.01%new13F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd24,680$149K<0.01%-13,98713F-HRTimelineGroup
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.in group LANDSCAPE CAPITAL MANAGEMENT,…21,515$130K0.01%new13F-HRTimelineGroup
BROWN ADVISORY INCin group BROWN ADVISORY INC20,854$126K<0.01%013F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC20,598$124K<0.01%+7,65413F-HRTimelineGroup
Sanctuary Advisors, LLC18,229$110K<0.01%-11,50313F-HRTimeline
OPPENHEIMER & CO INCin group OPPENHEIMER ASSET MANAGEMENT …15,500$93.5K<0.01%013F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc14,853$89.6K<0.01%+2,75113F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO14,709$88.7K<0.01%new13F-HRTimelineGroup
Abel Hall, LLC14,680$88.5K0.02%new13F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC14,316$85K<0.01%new13F-HRTimelineGroup
CIBC Asset Management Inc14,093$85K<0.01%new13F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC11,931$71.9K<0.01%new13F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…11,495$69.3K<0.01%-19413F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…11,251$67.8K<0.01%+77113F-HRTimelineGroup
XPONANCE LLC10,990$66.3K<0.01%new13F-HRTimeline
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding10,742$64.8K-209,089Timeline
Mariner, LLCin group Mariner, LLC10,000$60.3K<0.01%013F-HRTimelineGroup
SIMPLEX TRADING, LLC9,235$55.7K<0.01%-1,06713F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…8,720$52.6K<0.01%+26313F-HRTimeline
AMALGAMATED BANK4,449$27K<0.01%+46713F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA4,171$25K<0.01%-650,22413F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.3,998$24.1K<0.01%+33113F-HRTimeline
1620 INVESTMENT ADVISORS, INC.3,000$18.1K0.01%new13F-HRTimeline
COMERICA BANK2,105$12.7K<0.01%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…2,067$12.5K<0.01%-4,46413F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC1,582$9.54K<0.01%new13F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…1,530$9.23K<0.01%-30813F-HRTimelineGroup
Sterling Capital Management LLC925$5.58K<0.01%+64813F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.666$4.02K<0.01%-85813F-HRTimelineGroup
Larson Financial Group LLC639$3.85K<0.01%013F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.553$3K<0.01%013F-HRTimelineGroup
CWM, LLCin group CWM, LLC493$3K<0.01%+6113F-HRTimelineGroup
RAFFA WEALTH MANAGEMENT, LLC420$2.53K<0.01%013F-HRTimeline
Aster Capital Management (DIFC) Ltd269$1.62K<0.01%new13F-HRTimeline
Allworth Financial LP167$1.01K<0.01%-2,11213F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP146$880<0.01%new13F-HRTimelineGroup
NewEdge Advisors, LLC123$741<0.01%new13F-HRTimeline
GAMMA Investing LLC47$283<0.01%new13F-HRTimeline
Sunbelt Securities, Inc.25$151<0.01%013F-HRTimeline
Arax Advisory Partners14$84<0.01%-34913F-HRTimeline
ROTHSCHILD INVESTMENT LLC5$30<0.01%new13F-HRTimeline
SBI Securities Co., Ltd.3$18<0.01%-113F-HRTimeline
MAI Capital Management2$13<0.01%013F-HRTimeline
Cornerstone Planning Group LLC1$6<0.01%-4613F-HRTimeline