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Disclosery

TSHA TAYSHA GENE THERAPIES INC

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COMMON STOCK (common), issuer CIK 1806310

127 managers (128 13F filers) reported a position in TSHA shares at 2025-03-31, 166,854,162 shares in all. 21 filers opened a position and 25 filers sold out during the quarter.

Managers
127
13F filers
128
New
21
Added
38
Reduced
31
Sold out
25
Shares held by filers
166,854,162

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2025

Filers in the available 13F reports with a share position at 2025-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Avoro Capital Advisors LLC19,999,999$27.8M0.43%013F-HRTimeline
RTW INVESTMENTS, LP18,787,866$26.1M0.4%+10,115,23613F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY16,846,374$23.4M<0.01%-793,99213F-HRTimelineGroup
FMR LLCin group FMR LLC15,631,954$21.7M<0.01%-733,71013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.13,589,178$18.9M<0.01%+57,71113F-HRTimelineGroup
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.10,872,503$15.1M0.25%013F-HRTimelineGroup
Octagon Capital Advisors LP10,700,000$14.9M2.93%+250,00013F-HR/ATimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC8,770,921$12.2M<0.01%-135,84313F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.6,514,737$9.06M0.51%-87,73813F-HR/ATimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.4,569,678$6.35M0.02%new13F-HR/ATimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP4,004,756$5.57M0.06%013F-HRTimelineGroup
TYBOURNE CAPITAL MANAGEMENT (HK) LTD3,700,000$5.14M21.83%013F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC3,664,732$5.1M<0.01%+92,38313F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP3,233,512$4.49M<0.01%-3,240,85513F-HRTimelineGroup
Polar Capital Holdings Plcin group Polar Capital Holdings Plc3,000,000$4.17M0.03%013F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC1,772,654$2.46M<0.01%+1,621,04013F-HRTimelineGroup
Granahan Investment Management, LLC1,640,793$2.28M0.11%+4,41213F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP1,431,666$1.99M<0.01%-27,06613F-HRTimelineGroup
Palo Alto Investors LP1,419,468$1.97M0.38%+608,20013F-HRTimeline
B Group, Inc.1,255,556$1.75M1.52%+290,00013F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC1,066,309$1.48M0.29%+888,60213F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO1,003,067$1.39M<0.01%-1,640,68813F-HRTimelineGroup
Woodline Partners LP858,254$1.19M0.01%-169,26813F-HRTimeline
Quantum Private Wealth, LLC791,476$1.1M0.42%-3,50013F-HRTimeline
SUPERSTRING CAPITAL MANAGEMENT LP755,599$1.05M1.25%new13F-HRTimeline
Sands Capital Alternatives, LLC724,873$1.01M0.25%013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC708,966$985K<0.01%+373,72813F-HR/ATimelineGroup
Alphabet Inc.in group Alphabet Inc.640,882$891K0.06%013F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/636,842$885K<0.01%-1,073,46113F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…625,198$869K<0.01%+39,60413F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co547,128$761K<0.01%+72,87113F-HR/ATimelineGroup
Nuveen, LLCin group TIAA546,414$760K<0.01%13F-HRTimelineGroup
DAFNA Capital Management LLC522,500$726K0.21%013F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp453,420$630K<0.01%+3,15913F-HRTimelineGroup
UBS Group AGin group UBS Group AG418,132$581K<0.01%-3,26413F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC359,007$499K<0.01%-608,13713F-HR/ATimelineGroup
NorthCoast Asset Management LLC292,778$407K<0.01%013F-HR/ATimeline
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.245,254$341K0.01%new13F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…227,472$316K<0.01%+85,00913F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC216,611$301K<0.01%-528,59413F-HRTimelineGroup
RHUMBLINE ADVISERS205,462$286K<0.01%+13,38313F-HR/ATimeline
XTX Topco Ltdin group XTX Topco Ltd203,129$282K0.01%new13F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.159,899$222K<0.01%+72,54413F-HRTimelineGroup
Chicago Partners Investment Group LLC116,565$221K0.01%+52113F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC142,810$199K<0.01%+5,35013F-HRTimeline
HRT FINANCIAL LP139,692$194K<0.01%new13F-HRTimeline
EntryPoint Capital, LLC135,897$189K0.09%+74,40213F-HRTimeline
Privium Fund Management B.V.134,900$188K0.05%013F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\134,418$187K<0.01%-16,66513F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC133,194$185K<0.01%-120,09813F-HRTimelineGroup
BIT Capital GmbH117,062$163K0.02%new13F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources116,238$162K<0.01%new13F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding109,446$156K-5,987Timeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN109,048$152K<0.01%+5,66413F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.108,250$150K<0.01%013F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC107,899$150K<0.01%+82,54513F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…107,711$150K<0.01%+44,72113F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC99,912$139K<0.01%+31,87713F-HRTimeline
Corebridge Financial, Inc.in group Corebridge Financial, Inc.85,878$119K<0.01%-1,27213F-HRTimelineGroup
Y-Intercept (Hong Kong) Ltd83,864$117K0.01%new13F-HRTimeline
Leonteq Securities AG79,999$111K0.01%013F-HRTimeline
Creative Planningin group Creative Planning78,335$109K<0.01%+57,54713F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/74,025$103K<0.01%+8,69413F-HRTimeline
Virtus Investment Advisers, LLCgroup of 2 filers holding72,957$101K+41,360Timeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …63,797$88.7K<0.01%+78613F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC60,069$83K<0.01%+1,00013F-HRTimeline
Mariner, LLCin group Mariner, LLC58,490$81.3K<0.01%+14813F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC48,616$67.6K<0.01%-2,60013F-HR/ATimelineGroup
ProShare Advisors LLC47,195$65.6K<0.01%-11,88113F-HRTimeline
Police & Firemen's Retirement System of…45,678$63.5K<0.01%013F-HRTimeline
Jain Global LLC45,200$62.8K<0.01%new13F-HRTimeline
China Universal Asset Management Co., L…41,120$57.2K0.01%-2,33613F-HRTimeline
Williams & Novak Wealth Management, LLC45,000$56.9K0.06%013F-HRTimeline
CIBC WORLD MARKETS CORP38,897$54.1K<0.01%+22,49213F-HRTimeline
FIRST MANHATTAN CO. LLC.28,500$39.6K<0.01%013F-HRTimeline
Cambridge Investment Research Advisors,…23,490$33K<0.01%013F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC22,844$31.8K<0.01%-14913F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…22,700$31.6K<0.01%+2,69013F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND21,100$29.3K<0.01%013F-HR/ATimeline
Lee Financial Co20,000$27.8K<0.01%013F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc19,958$27.7K<0.01%-6013F-HRTimelineGroup
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC20,257$27.7K<0.01%-13413F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC19,017$26.4K<0.01%+1613F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…15,672$21.8K<0.01%013F-HRTimelineGroup
Point72 (DIFC) Ltd15,528$21.6K<0.01%new13F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC15,140$21K<0.01%+2,15013F-HRTimelineGroup
Howard Capital Management, LLC14,165$19.7K<0.01%013F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC13,989$19.4K<0.01%-98213F-HRTimelineGroup
TWO SIGMA SECURITIES, LLC13,071$18.2K<0.01%new13F-HRTimeline
XPONANCE LLC12,639$17.6K<0.01%+71413F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…12,635$17.6K<0.01%013F-HRTimeline
Marex Group Ltdin group Marex Group Ltd12,500$17.4K<0.01%013F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS12,241$17K<0.01%-11,40313F-HRTimelineGroup
SIH Partners, LLLPin group SIH Partners, LLLP12,173$16.9K<0.01%new13F-HRTimelineGroup
Catalyst Funds Management Pty Ltd11,900$16.5K<0.01%new13F-HRTimeline
Camelot Portfolios, LLC11,000$15.3K0.01%new13F-HRTimeline
CWM, LLCin group CWM, LLC10,527$15K<0.01%+10,26213F-HRTimelineGroup
Bordeaux Wealth Advisors LLC10,109$14.1K<0.01%new13F-HRTimeline
MACKENZIE FINANCIAL CORP10,000$13.9K<0.01%013F-HRTimeline
Capital Investment Advisors, LLC10,000$13.9K<0.01%013F-HRTimeline
ATTICUS WEALTH MANAGEMENT, LLC7,425$10.3K<0.01%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…6,864$9.54K<0.01%-44,22113F-HRTimelineGroup
AMALGAMATED BANK5,534$8K<0.01%013F-HRTimeline
CIBC Private Wealth Group LLCin group CIBC Bancorp USA Inc.6,833$7.72K<0.01%013F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.5,248$7.29K<0.01%+94513F-HRTimeline
NISA INVESTMENT ADVISORS, LLC4,230$5.88K<0.01%+3,42313F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA1,462$2K<0.01%-5,07313F-HR/ATimelineGroup
Allworth Financial LP1,000$1.82K<0.01%013F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…1,000$1.39K<0.01%013F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\931$1.29K<0.01%+20313F-HRTimelineGroup
Caitong International Asset Management …814$1.13K<0.01%new13F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.805$1.12K<0.01%-54813F-HRTimelineGroup
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.691$1K<0.01%013F-HRTimelineGroup
SIGNATUREFD, LLC553$769<0.01%+27113F-HRTimeline
Lindbrook Capital, LLC435$605<0.01%-33513F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…372$517<0.01%new13F-HRTimelineGroup
CoreCap Advisors, LLC290$403<0.01%-9013F-HRTimeline
Parallel Advisors, LLC280$389<0.01%013F-HRTimeline
Morton Brown Family Wealth, LLC260$361<0.01%013F-HRTimeline
COLDSTREAM CAPITAL MANAGEMENT INC207$288<0.01%new13F-HRTimeline
Sterling Capital Management LLC165$229<0.01%013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.134$187<0.01%013F-HRTimelineGroup
True Wealth Design, LLC132$184<0.01%new13F-HRTimeline
SBI Securities Co., Ltd.80$111<0.01%013F-HRTimeline
QUADRANT CAPITAL GROUP LLC2$3<0.01%new13F-HRTimeline
Capital Advisors, Ltd. LLC79$00%013F-HRTimelineValue filed as zero, left out of ratios.
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.