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Disclosery

TSHA TAYSHA GENE THERAPIES INC

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COMMON STOCK (common), issuer CIK 1806310

182 managers (191 13F filers) reported a position in TSHA shares at 2026-03-31, 265,628,517 shares in all. 26 filers opened a position and 35 filers sold out during the quarter.

Managers
182
13F filers
191
New
26
Added
69
Reduced
49
Sold out
35
Shares held by filers
265,628,517

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2026

Filers in the available 13F reports with a share position at 2026-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.23,555,648$105M1.12%013F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC22,369,645$100M0.01%+8,676,90613F-HRTimelineGroup
Avoro Capital Advisors LLC21,700,000$97M0.96%013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.18,365,608$82.1M<0.01%-277,52113F-HRTimelineGroup
Vestal Point Capital, LP18,000,000$80.5M2.25%+4,250,00013F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY17,965,371$80.3M<0.01%-113,14713F-HRTimelineGroup
FMR LLCin group FMR LLC14,321,255$64M<0.01%+792,88913F-HRTimelineGroup
VANGUARD GROUP INCgroup of 7 filers holding14,040,485$62.8MnewTimeline
RTW INVESTMENTS, LP13,680,248$61.2M0.61%-2,718,04913F-HRTimeline
STATE STREET CORPin group STATE STREET CORP11,209,078$50.1M<0.01%+418,99413F-HRTimelineGroup
Octagon Capital Advisors LP8,859,911$39.6M4.38%013F-HRTimeline
Siren, L.L.C.in group Siren, L.L.C.8,829,913$39.5M1.09%-1,300,00013F-HRTimelineGroup
Polar Capital Holdings Plcin group Polar Capital Holdings Plc5,654,340$25.3M0.11%-2,277,06313F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC5,531,955$24.7M<0.01%+144,92913F-HRTimelineGroup
GordonMD Global Investments LPin group GordonMD Global Investments LP737,550$22.2M15.47%-593,35113F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.4,427,301$19.8M0.02%+413,66613F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP4,004,756$17.9M0.1%013F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC3,281,820$14.7M0.01%+102,95713F-HRTimelineGroup
Casdin Capital, LLC3,250,000$14.5M1.1%+1,750,00013F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC2,979,429$13.3M0.8%+483,62013F-HRTimelineGroup
HEALTHCARE OF ONTARIO PENSION PLAN TRUS…2,883,301$12.9M0.02%-838,69913F-HRTimeline
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…2,722,165$12.2M0.14%013F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC2,812,010$11.4M<0.01%-2,726,99113F-HRTimelineGroup
SG Americas Securities, LLC2,176,742$9.73M0.01%+1,395,26813F-HRTimeline
RICE HALL JAMES & ASSOCIATES, LLC1,944,671$8.69M0.48%+674,02613F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP1,814,318$8.11M<0.01%+576,33113F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co1,808,599$8.08M<0.01%-94,37913F-HRTimelineGroup
B Group, Inc.1,800,556$8.05M5.97%013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/1,677,046$7.5M<0.01%+524,36613F-HRTimelineGroup
Palo Alto Investors LP1,391,382$6.22M0.95%+208,18713F-HRTimeline
Aberdeen Group plcin group Aberdeen Group plc1,021,063$4.56M0.01%013F-HRTimelineGroup
Affinity Asset Advisors, LLC1,000,000$4.47M0.26%-2,300,00013F-HRTimeline
Granahan Investment Management, LLC883,241$3.95M0.19%+179,27013F-HRTimeline
Quantum Private Wealth, LLC849,212$3.8M1.17%+29,49713F-HRTimeline
UBS Group AGgroup of 2 filers holding783,493$3.5M+232,950Timeline
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP742,081$3.32M<0.01%+390,95513F-HRTimelineGroup
Sands Capital Alternatives, LLC724,873$3.24M0.77%013F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO754,782$3.07M<0.01%-19,63013F-HR/ATimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…626,361$2.8M<0.01%-84,87413F-HRTimelineGroup
Seven Fleet Capital Management LP625,708$2.8M0.88%+458,48513F-HR/ATimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp608,123$2.72M<0.01%-16,24413F-HRTimelineGroup
Nuveen, LLCin group TIAA549,153$2.45M<0.01%+3,86713F-HRTimelineGroup
Woodline Partners LP513,828$2.3M0.01%+13,82813F-HR/ATimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC511,983$2.29M<0.01%+293,79813F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP490,472$2.18M<0.01%013F-HRTimelineGroup
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.479,000$2.14M0.03%+454,00013F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.461,856$2.06M<0.01%-3,406,82613F-HRTimelineGroup
ACUTA CAPITAL PARTNERS, LLC439,464$1.96M1.4%-15,36313F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC413,203$1.85M<0.01%+242,10313F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC411,135$1.84M<0.01%-1,443,72013F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC410,282$1.83M<0.01%-61,29513F-HRTimelineGroup
Hennion & Walsh Asset Management, Inc.391,476$1.75M0.06%+83,01913F-HRTimeline
Invesco Ltd.in group Invesco Ltd.368,021$1.65M<0.01%-964,75913F-HRTimelineGroup
MOORE CAPITAL MANAGEMENT, LP328,831$1.47M0.05%new13F-HRTimeline
POLEN CAPITAL MANAGEMENT LLC319,748$1.43M0.01%+163,16213F-HRTimeline
Rafferty Asset Management, LLC299,903$1.34M0.01%-44,88113F-HRTimeline
Ensign Peak Advisors, Inc275,111$1.23M<0.01%013F-HR/ATimeline
Swiss National Bank268,800$1.2M<0.01%013F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD263,332$1.18M<0.01%+150,15413F-HRTimeline
RHUMBLINE ADVISERS258,530$1.16M<0.01%+1,09013F-HRTimeline
SUPERSTRING CAPITAL MANAGEMENT LP258,269$1.15M0.82%-722,49913F-HRTimeline
Chicago Partners Investment Group LLC170,751$1.15M0.03%+4,21013F-HRTimeline
ALLIANCEBERNSTEIN L.P.189,240$1.04M<0.01%+9,60013F-HRTimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC222,986$997K<0.01%-1,93413F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC195,745$875K<0.01%-1913F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN183,334$820K<0.01%-121,75213F-HR/ATimelineGroup
PANAGORA ASSET MANAGEMENT INC182,164$814K<0.01%+170,59013F-HRTimeline
Privium Fund Management B.V.181,900$813K0.17%+17,00013F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\181,769$813K<0.01%+20,99013F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC177,309$793K<0.01%+8,44713F-HRTimelineGroup
WEXFORD CAPITAL LP160,654$718K0.12%-20,19913F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/158,954$711K<0.01%+37,14013F-HRTimeline
Palumbo Wealth Management LLC146,709$656K0.16%-31,29813F-HRTimeline
TUDOR INVESTMENT CORP ET AL143,575$642K<0.01%new13F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding139,017$613K+3,067Timeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…136,933$612K<0.01%-1,64713F-HRTimeline
PROFUND ADVISORS LLC134,671$602K0.02%+6,08113F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS120,200$537K<0.01%-52,28213F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…120,116$537K<0.01%+6,85013F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…116,297$520K<0.01%-8,67813F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources108,399$485K<0.01%013F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc104,308$466K<0.01%-28,83813F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …99,371$444K<0.01%+32,28613F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management83,019$371K<0.01%+40,94913F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…80,779$361K<0.01%+13,30213F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson69,000$308K<0.01%013F-HR/ATimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND67,500$302K<0.01%013F-HRTimeline
RED REEF ADVISORS LLC65,950$295K0.31%013F-HRTimeline
Creative Planningin group Creative Planning59,801$267K<0.01%-3,43413F-HRTimelineGroup
VARCOV Co.58,511$262K0.1%new13F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC58,442$261K<0.01%+2,78513F-HRTimeline
Abacus Wealth Partners, LLC58,241$260K0.02%+3,06813F-HRTimeline
Police & Firemen's Retirement System of…57,168$256K<0.01%013F-HRTimeline
CITIGROUP INCin group CITIGROUP INC57,080$255K<0.01%-5,93513F-HRTimelineGroup
Mitsubishi UFJ Asset Management Co., Lt…in group Mitsubishi UFJ Trust & Bankin…56,577$253K<0.01%-1,39813F-HRTimelineGroup
LANARK FINANCIAL, INC.54,058$242K0.02%+1,10313F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO51,472$230K<0.01%+3,61413F-HRTimelineGroup
China Universal Asset Management Co., L…48,609$217K0.02%+3,97413F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC47,988$215K<0.01%-23,08113F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…47,095$211K0.06%+1,14913F-HRTimelineGroup
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…46,807$209K<0.01%new13F-HRTimelineGroup
Militia Capital Management LLCin group Militia Capital Management LLC46,500$208K0.05%13F-HR/ATimelineGroup
ProShare Advisors LLC44,267$198K<0.01%-8,19613F-HRTimeline
FIRST MANHATTAN CO. LLC.43,500$194K<0.01%013F-HRTimeline
Williams & Novak Wealth Management, LLC45,000$194K0.15%013F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE42,400$190K<0.01%013F-HRTimelineGroup
Aquatic Capital Management LLC39,856$178K0.01%new13F-HRTimeline
E Fund Management Co., Ltd.37,699$169K0.01%13F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM37,619$168K<0.01%-5813F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC33,820$151K<0.01%-52,91013F-HRTimelineGroup
J. Goldman & Co LP33,750$151K0.01%013F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC33,654$150K<0.01%+13,47613F-HRTimelineGroup
KLP KAPITALFORVALTNING AS29,300$131K<0.01%013F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC28,511$127K<0.01%-4,40713F-HRTimeline
Cetera Investment Advisers28,450$127K<0.01%+7,29613F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…26,084$117K<0.01%+25,60913F-HRTimelineGroup
Quadrature Capital Ltdin group Quadrature Capital Ltd23,499$105K<0.01%new13F-HRTimelineGroup
Cambridge Investment Research Advisors,…22,380$100K<0.01%+30013F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC22,031$98.5K<0.01%+3,88713F-HRTimelineGroup
Legato Capital Management LLC21,782$97.4K0.01%+6,75913F-HRTimeline
Scientech Research LLC21,040$94K0.08%+2,86413F-HRTimeline
XPONANCE LLC20,033$89.5K<0.01%+2,81513F-HRTimeline
Lee Financial Co20,000$89.4K0.01%013F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…19,318$86.4K<0.01%013F-HRTimelineGroup
TEACHER RETIREMENT SYSTEM OF TEXAS17,784$79.5K<0.01%-2,05313F-HRTimeline
Ameritas Investment Partners, Inc.group of 2 filers holding17,673$79K+1Timeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…16,929$75.7K<0.01%013F-HRTimelineGroup
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC16,585$74.1K<0.01%+5,47413F-HRTimelineGroup
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC16,185$72.3K<0.01%+3,36213F-HRTimelineGroup
Catalyst Funds Management Pty Ltd15,100$67.5K0.01%new13F-HRTimeline
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/13,668$61.1K<0.01%-4013F-HRTimelineGroup
Virtu Financial LLCin group Virtu Financial LLC13,346$60K<0.01%new13F-HRTimelineGroup
CWM, LLCin group CWM, LLC13,081$58.5K<0.01%-1213F-HRTimelineGroup
Ethic Inc.12,986$58K<0.01%-9,74913F-HRTimeline
Allegheny Financial Group12,000$53.6K0.01%-14,35013F-HRTimeline
CIBC Asset Management Inc11,959$53.5K<0.01%013F-HRTimeline
Y-Intercept (Hong Kong) Ltd11,486$51.3K<0.01%new13F-HRTimeline
Magnetar Financial LLCin group Magnetar Financial LLC11,409$51K<0.01%new13F-HRTimelineGroup
R Squared Ltd11,276$50.4K0.03%new13F-HRTimeline
Summit Financial, LLC11,148$49.8K<0.01%new13F-HRTimeline
CIBC Bancorp USA Inc.in group CIBC Bancorp USA Inc.11,121$49.7K<0.01%13F-HRTimelineGroup
NEUBERGER BERMAN GROUP LLCin group NEUBERGER BERMAN GROUP LLC10,823$48.4K<0.01%new13F-HRTimelineGroup
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…10,740$48K<0.01%new13F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd10,329$46.2K<0.01%new13F-HRTimelineGroup
CHOREO, LLC10,044$44.9K<0.01%new13F-HRTimeline
Capital Investment Advisors, LLC10,000$44.7K<0.01%013F-HR/ATimeline
ST GERMAIN D J CO INCin group ST GERMAIN D J CO INC9,633$43.1K<0.01%013F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.6,128$27.4K<0.01%+74513F-HRTimeline
Allworth Financial LP5,443$24.3K<0.01%+5,22013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC5,107$22.8K<0.01%-40513F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…5,000$22.4K<0.01%013F-HRTimelineGroup
Federation des caisses Desjardins du Qu…5,000$22.4K<0.01%new13F-HRTimeline
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …2,454$11K<0.01%new13F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.2,020$9.03K<0.01%+1,74313F-HRTimelineGroup
Chung Wu Investment Group, LLC2,000$8.94K0.01%-2,00013F-HRTimeline
INTERNATIONAL ASSETS INVESTMENT MANAGEM…2,000$8.62K<0.01%013F-HRTimeline
Sterling Capital Management LLC1,411$6.31K<0.01%013F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…1,043$4.66K<0.01%-1113F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\1,007$4.5K<0.01%+9513F-HRTimelineGroup
Caitong International Asset Management …926$4.14K<0.01%-24,65113F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.864$3.86K<0.01%-7013F-HR/ATimelineGroup
Quantbot Technologies LP524$2.34K<0.01%new13F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP561$2.28K<0.01%new13F-HRTimelineGroup
Essential Partners LLC327$1.46K<0.01%013F-HRTimeline
Sound Income Strategies, LLC325$1.4K<0.01%013F-HRTimeline
Parallel Advisors, LLC286$1.28K<0.01%+613F-HR/ATimeline
SIGNATUREFD, LLC266$1.19K<0.01%+20613F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA191$1K<0.01%-6,11113F-HRTimelineGroup
ROTHSCHILD INVESTMENT LLC170$760<0.01%+10013F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…141$630<0.01%+5013F-HR/ATimelineGroup
GAMMA Investing LLC135$603<0.01%-14113F-HRTimeline
Larson Financial Group LLC128$572<0.01%new13F-HRTimeline
Root Financial Partners, LLC72$322<0.01%new13F-HRTimeline
Farther Finance Advisors, LLC55$237<0.01%013F-HRTimeline
True Wealth Design, LLC30$135<0.01%013F-HRTimeline
SBI Securities Co., Ltd.15$67<0.01%013F-HRTimeline
IFP Advisors, Inc14$63<0.01%013F-HRTimeline
MAI Capital Management13$59<0.01%+513F-HRTimeline
Keating Financial Advisory Services, In…13$58<0.01%new13F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC8$36<0.01%013F-HRTimelineGroup
Capital Advisors, Ltd. LLC79$00%+213F-HRTimelineValue filed as zero, left out of ratios.
Covestor Ltd27$00%new13F-HRTimelineValue filed as zero, left out of ratios.