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Disclosery

TSHA TAYSHA GENE THERAPIES INC

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COMMON STOCK (common), issuer CIK 1806310

131 managers (132 13F filers) reported a position in TSHA shares at 2024-12-31, 167,474,788 shares in all. 23 filers opened a position and 15 filers sold out during the quarter.

Managers
131
13F filers
132
New
23
Added
44
Reduced
28
Sold out
15
Shares held by filers
167,474,788

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2024

Filers in the available 13F reports with a share position at 2024-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Avoro Capital Advisors LLC19,999,999$34.6M0.49%+1,349,99913F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY17,640,366$30.5M<0.01%+9,976,37313F-HR/ATimelineGroup
FMR LLCin group FMR LLC16,365,664$28.3M<0.01%-2,312,86313F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.13,531,467$23.4M<0.01%+10,93413F-HRTimelineGroup
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.10,872,503$18.8M0.25%013F-HRTimelineGroup
Octagon Capital Advisors LP10,450,000$18.1M3.08%+5,877,77813F-HRTimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC8,906,764$15.4M<0.01%+641,30513F-HRTimelineGroup
RTW INVESTMENTS, LP8,672,630$15M0.23%-6,273,79013F-HRTimeline
Siren, L.L.C.in group Siren, L.L.C.6,602,475$11.4M0.5%+1,722,60013F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP6,474,367$11.2M<0.01%+3,005,29913F-HRTimelineGroup
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…5,000,000$8.65M0.02%new13F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP4,004,756$6.93M0.07%013F-HRTimelineGroup
TYBOURNE CAPITAL MANAGEMENT (HK) LTD3,700,000$6.4M1.61%013F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC3,572,349$6.18M<0.01%+9,59113F-HRTimelineGroup
Venrock Adviser, LLC3,225,180$5.58M0.38%-5,774,82013F-HRTimeline
Polar Capital Holdings Plcin group Polar Capital Holdings Plc3,000,000$5.19M0.03%-25,00013F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO2,643,755$4.57M<0.01%-357,64213F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/1,710,303$2.96M<0.01%+1,576,56813F-HRTimelineGroup
Granahan Investment Management, LLC1,636,381$2.83M0.12%+496,48213F-HRTimeline
NORGES BANK1,461,120$2.53M<0.01%new13F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP1,458,732$2.52M<0.01%+86,20713F-HRTimelineGroup
Woodline Partners LP1,027,522$1.78M0.01%+2813F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC967,144$1.67M<0.01%-238,52713F-HRTimelineGroup
B Group, Inc.965,556$1.67M1.02%13F-HRTimeline
ACUTA CAPITAL PARTNERS, LLC884,244$1.53M1.54%-1,234,74813F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC878,448$1.52M<0.01%new13F-HRTimeline
Palo Alto Investors LP811,268$1.4M0.22%013F-HRTimeline
Quantum Private Wealth, LLC794,976$1.38M0.44%+27,36013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC745,205$1.29M<0.01%-2,114,76713F-HRTimelineGroup
Sands Capital Alternatives, LLC724,873$1.25M0.27%013F-HRTimeline
Alphabet Inc.in group Alphabet Inc.640,882$1.11M0.06%013F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…585,594$1.01M<0.01%+122,40213F-HRTimelineGroup
Nuveen Asset Management, LLCin group TIAA546,414$945K<0.01%-20,43613F-HRTimelineGroup
DAFNA Capital Management LLC522,500$904K0.23%new13F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co474,257$820K<0.01%+11,39013F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp450,261$779K<0.01%+111,98913F-HRTimelineGroup
UBS Group AGin group UBS Group AG421,396$729K<0.01%+329,39513F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC335,238$587K<0.01%+87,95813F-HR/ATimelineGroup
NorthCoast Asset Management LLC292,778$507K<0.01%013F-HR/ATimeline
CITIGROUP INCin group CITIGROUP INC253,292$438K<0.01%+120,68013F-HRTimelineGroup
Rafferty Asset Management, LLC252,257$436K<0.01%new13F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC211,842$366K<0.01%+108,71913F-HRTimelineGroup
RHUMBLINE ADVISERS192,079$332K<0.01%+5,83113F-HR/ATimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC177,707$307K0.06%-73,69313F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC169,575$293K<0.01%+62,00313F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC151,614$262K<0.01%new13F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\151,083$261K<0.01%-2,409,20113F-HR/ATimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…142,463$246K<0.01%-34,02913F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP138,111$239K<0.01%-347,91513F-HRTimelineGroup
LOS ANGELES CAPITAL MANAGEMENT LLC137,460$238K<0.01%-69,53213F-HRTimeline
Privium Fund Management B.V.134,900$233K0.05%+14,90013F-HRTimeline
Chicago Partners Investment Group LLC116,044$224K0.01%-2,13113F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding115,433$200K+19,968Timeline
ALLIANCEBERNSTEIN L.P.108,250$187K<0.01%013F-HRTimeline
Virtu Financial LLCin group Virtu Financial LLC107,544$186K0.01%new13F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN103,384$179K<0.01%+31,45713F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.87,355$151K<0.01%+1,67413F-HRTimelineGroup
Corebridge Financial, Inc.in group Corebridge Financial, Inc.87,150$151K<0.01%-4,94813F-HRTimelineGroup
Leonteq Securities AG79,999$138K0.01%-113F-HRTimeline
Aquatic Capital Management LLC78,246$135K<0.01%new13F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC68,035$118K<0.01%+25,94113F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/65,331$114K<0.01%+5,61213F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …63,011$109K<0.01%+2,34613F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…62,990$109K<0.01%-13,04713F-HRTimelineGroup
EntryPoint Capital, LLC61,495$106K0.04%+34,46813F-HRTimeline
LPL Financial LLC60,000$104K<0.01%new13F-HRTimeline
ProShare Advisors LLC59,076$102K<0.01%+14,41813F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC59,069$102K<0.01%+31,00013F-HRTimeline
Mariner, LLCin group Mariner, LLC58,342$101K<0.01%+45,00613F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC51,216$88.6K<0.01%-3,82813F-HR/ATimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…51,085$88.4K<0.01%+37,23313F-HRTimelineGroup
PROFUND ADVISORS LLC50,242$86.9K<0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…45,678$79K<0.01%13F-HRTimeline
Williams & Novak Wealth Management, LLC45,000$77.8K0.08%013F-HRTimeline
China Universal Asset Management Co., L…43,456$75.2K0.01%+4,03913F-HRTimeline
Engineers Gate Manager LP35,808$61.9K<0.01%new13F-HRTimeline
Verition Fund Management LLC34,098$59K<0.01%new13F-HRTimeline
VIRTUS ADVISERS, LLCin group Virtus Investment Advisers, L…31,597$54.7K0.02%+9,49413F-HRTimelineGroup
FIRST MANHATTAN CO. LLC.28,500$49.3K<0.01%new13F-HRTimeline
SG Americas Securities, LLC28,498$49K<0.01%-35,48613F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC25,354$43.9K<0.01%-44,11713F-HRTimelineGroup
Cambridge Investment Research Advisors,…23,490$41K<0.01%-1513F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS23,644$40.9K<0.01%new13F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC22,993$39.8K<0.01%new13F-HRTimelineGroup
AXQ CAPITAL, LP22,432$38.8K0.02%new13F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND21,100$36.5K<0.01%013F-HR/ATimeline
Creative Planningin group Creative Planning20,788$36K<0.01%+6,67013F-HRTimelineGroup
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC20,391$35.6K<0.01%+8,07613F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc20,018$34.6K<0.01%013F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…20,010$34.6K<0.01%013F-HRTimeline
Lee Financial Co20,000$34.6K<0.01%013F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC19,001$32.9K<0.01%-1,00613F-HRTimeline
E Fund Management Co., Ltd.17,844$30.9K<0.01%new13F-HRTimeline
CIBC WORLD MARKETS CORP16,405$28.4K<0.01%new13F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…15,672$27.1K<0.01%013F-HRTimelineGroup
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC14,971$25.9K<0.01%-82813F-HRTimelineGroup
Ground Swell Capital, LLC14,660$25.4K0.06%new13F-HRTimeline
Howard Capital Management, LLC14,165$24.5K<0.01%013F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC12,990$22.5K<0.01%+1,80013F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…12,635$21.9K<0.01%013F-HR/ATimeline
Marex Group Ltdin group Marex Group Ltd12,500$21.6K<0.01%013F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP12,300$21.3K<0.01%new13F-HRTimelineGroup
XPONANCE LLC11,925$20.6K<0.01%+1,05613F-HRTimeline
MACKENZIE FINANCIAL CORP10,000$17.3K<0.01%013F-HR/ATimeline
Capital Investment Advisors, LLC10,000$17.3K<0.01%013F-HRTimeline
CIBC Private Wealth Group LLCin group CIBC Bancorp USA Inc.6,833$13.2K<0.01%013F-HRTimelineGroup
ATTICUS WEALTH MANAGEMENT, LLC7,425$12.8K<0.01%013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA6,535$11K<0.01%-29,80513F-HRTimelineGroup
AMALGAMATED BANK5,534$10K<0.01%013F-HRTimeline
Brooklyn Investment Group4,500$7.79K<0.01%new13F-HRTimeline
GF FUND MANAGEMENT CO. LTD.4,303$7.44K<0.01%13F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.1,353$2.34K<0.01%+74713F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…1,000$1.73K<0.01%013F-HRTimelineGroup
Allworth Financial LP1,000$1.53K<0.01%013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC807$1.4K<0.01%+30313F-HRTimeline
Lindbrook Capital, LLC770$1.33K<0.01%+54613F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\728$1.26K<0.01%-13213F-HRTimelineGroup
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.691$1K<0.01%013F-HRTimelineGroup
CoreCap Advisors, LLC380$657<0.01%new13F-HRTimeline
SIGNATUREFD, LLC282$488<0.01%+10713F-HRTimeline
Parallel Advisors, LLC280$484<0.01%013F-HRTimeline
Morton Brown Family Wealth, LLC260$450<0.01%013F-HRTimeline
Sterling Capital Management LLC165$285<0.01%013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.134$233<0.01%013F-HR/ATimelineGroup
ROTHSCHILD INVESTMENT LLC130$225<0.01%new13F-HRTimeline
R Squared Ltd130$225<0.01%13F-HRTimeline
SBI Securities Co., Ltd.80$138<0.01%13F-HRTimeline
CWM, LLCin group CWM, LLC265$00%-23413F-HRTimelineGroupValue filed as zero, left out of ratios.
LAZARD ASSET MANAGEMENT LLCin group LAZARD ASSET MANAGEMENT LLC154$00%013F-HRTimelineGroupValue filed as zero, left out of ratios.
Capital Advisors, Ltd. LLC79$00%013F-HRTimelineValue filed as zero, left out of ratios.
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$00%013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.