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Disclosery

MDGL MADRIGAL PHARMACEUTICALS INC

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Stock (common), issuer CIK 1157601

377 managers (389 13F filers) reported a position in MDGL shares at 2025-12-31, 23,569,032 shares in all. 72 filers opened a position and 41 filers sold out during the quarter.

Managers
377
13F filers
389
New
72
Added
137
Reduced
113
Sold out
41
Shares held by filers
23,569,032

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP2,141,701$1.25B7.3%013F-HRTimelineGroup
RTW INVESTMENTS, LP1,993,687$1.16B11.63%013F-HRTimeline
VANGUARD GROUP INCgroup of 2 filers holding1,810,143$1.05B-3,000Timeline
Avoro Capital Advisors LLC1,807,500$1.05B10.35%-25,50013F-HR/ATimeline
PAULSON & CO. INC.1,707,522$994M30.48%-200,00113F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.1,644,750$958M0.02%+85,03813F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson1,584,843$918M0.41%-257,84713F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP583,003$340M0.01%-75,09413F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…461,402$269M0.05%+56,94713F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC451,743$263M0.02%+5,51013F-HRTimelineGroup
FMR LLCin group FMR LLC439,398$256M0.01%+38,26213F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/416,025$242M0.02%+171,73313F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.365,314$213M0.02%+65,74913F-HRTimelineGroup
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC354,220$206M0.58%-57,58213F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/313,659$183M0.02%-38,86113F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC305,847$178M0.03%-80,25313F-HR/ATimelineGroup
Polar Capital Holdings Plcin group Polar Capital Holdings Plc270,151$157M0.72%+4,99713F-HRTimelineGroup
ARMISTICE CAPITAL, LLC265,705$155M3.79%+145,72313F-HRTimeline
Hood River Capital Management LLC247,560$144M1.58%+4,75213F-HRTimeline
LORD, ABBETT & CO. LLC244,796$143M0.44%+142,65313F-HRTimeline
ALKEON CAPITAL MANAGEMENT LLC240,000$140M0.61%+120,00013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co219,099$128M0.02%+5,44713F-HRTimelineGroup
Artisan Partners Limited Partnership198,693$116M0.18%-7,56113F-HRTimeline
NORGES BANK196,393$114M0.01%new13F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\192,109$112M0.04%+154,76713F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC185,116$108M0.05%+19,50113F-HRTimelineGroup
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…181,949$106M0.1%-9,84713F-HRTimelineGroup
Fiera Capital Corpin group Fiera Capital Corp169,456$98.7M0.31%+41,65613F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP151,802$88.4M0.01%-8,18613F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY150,462$87.6M0.01%-99,18513F-HR/ATimelineGroup
Erste Asset Management GmbHin group Erste Asset Management GmbH141,100$82.3M0.69%-60,00013F-HRTimelineGroup
Rock Springs Capital Management LP139,618$81.3M4.17%+1,87213F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp136,869$79.7M0.01%+39,09013F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding126,487$73.7M-114,332Timeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.126,435$73.6M0.12%+85,20213F-HRTimelineGroup
Woodline Partners LP125,659$73.2M0.28%+21,81213F-HRTimeline
Nuveen, LLCin group TIAA118,363$68.9M0.02%+44,64813F-HRTimelineGroup
Driehaus Capital Management LLC111,666$65M0.44%-4,30813F-HRTimeline
MPM BIOIMPACT LLC96,780$56.4M6.45%-3,63513F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC93,114$54.2M0.06%-2,62013F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.88,554$51.6M0.04%-7,62813F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources86,076$50.1M0.01%+10,50613F-HRTimelineGroup
Tri Locum Partners LP86,023$50.1M6.5%+18,31713F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC83,862$48.8M0.08%-36,82013F-HRTimeline
ArrowMark Colorado Holdings LLC82,624$48.1M1.06%-40,63513F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND75,933$44.2M0.06%+6,66013F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC74,934$43.6M0.09%+44,99813F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS73,707$42.9M0.03%+2,95013F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding70,716$41.2M-40,352Timeline
First Light Asset Management, LLC66,831$38.9M2.98%+55,29213F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC66,724$38.9M0.01%-3,86013F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC64,254$37.4M0.04%+4,81713F-HRTimelineGroup
EMERALD ADVISERS, LLCgroup of 2 filers holding63,909$37.2M-21,919Timeline
Candriam S.C.A.63,906$37.2M0.19%+13,94113F-HR/ATimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding61,192$35.6M-742Timeline
Connor, Clark & Lunn Investment Managem…58,295$33.9M0.09%-27,47813F-HRTimeline
Jain Global LLC52,721$30.7M0.3%new13F-HRTimeline
Ensign Peak Advisors, Inc51,010$29.7M0.05%-2,25713F-HR/ATimeline
EULAV Asset Management49,000$28.5M0.76%-2,00013F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…48,159$28M0.03%+3,27413F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD46,120$26.9M0.02%+37,12013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN43,457$25.3M<0.01%+5,63913F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO40,079$23.3M<0.01%-7,74513F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP39,578$23M0.02%+38,87813F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC38,720$22.5M0.01%-11,19213F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC36,134$21M0.01%-12,23813F-HRTimelineGroup
Atika Capital Management LLCin group Atika Capital Management LLC34,000$19.8M2.76%new13F-HRTimelineGroup
SEGALL BRYANT & HAMILL, LLC33,520$19.5M0.26%+11,03013F-HRTimeline
GILDER GAGNON HOWE & CO LLC33,468$19.5M0.21%+2,62013F-HRTimeline
Public Sector Pension Investment Board32,871$19.1M0.06%new13F-HRTimeline
California Public Employees Retirement …31,286$18.2M0.01%+7,18913F-HRTimeline
Affinity Asset Advisors, LLC31,131$18.1M1.3%-83,86913F-HRTimeline
GROUPAMA ASSET MANAGMENT30,620$17.8M0.26%+3,17613F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC29,287$17.1M<0.01%+16,29013F-HRTimelineGroup
SCHRODER INVESTMENT MANAGEMENT GROUP29,051$17M0.01%+12,43913F-HRTimeline
Swiss National Bank28,580$16.6M0.01%+68013F-HRTimeline
STEADFAST CAPITAL MANAGEMENT LP26,850$15.6M0.27%-2,95013F-HRTimeline
Rheos Capital Works Inc.26,215$15.3M0.98%-17,00013F-HRTimeline
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP24,819$14.5M0.01%+21,02413F-HRTimelineGroup
RHUMBLINE ADVISERS23,691$13.8M0.01%-3,57213F-HRTimeline
CITIGROUP INCin group CITIGROUP INC23,327$13.6M0.01%+13,67913F-HRTimelineGroup
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…23,226$13.5M0.02%-65,27413F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO23,076$13.4M0.01%+3,96113F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.21,912$12.8M<0.01%-13,78313F-HRTimeline
Tao Capital Management LP21,000$12.2M10.53%-20,00013F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…19,661$11.4M0.02%+1,21013F-HR/ATimelineGroup
Rhenman & Partners Asset Management AB19,550$11.4M1.06%+1,30013F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP19,321$11.3M<0.01%+13,52213F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC19,221$11.2M0.14%-1,73513F-HRTimelineGroup
Bridgewater Associates, LP19,218$11.2M0.04%-8,56713F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …19,076$11.1M0.02%+3,78813F-HRTimelineGroup
NEUBERGER BERMAN GROUP LLCin group NEUBERGER BERMAN GROUP LLC18,660$10.9M0.01%+12913F-HRTimelineGroup
STEMPOINT CAPITAL LP17,736$10.3M1.77%+9,52913F-HRTimeline
WCM INVESTMENT MANAGEMENT, LLC17,254$10.1M0.02%-1,03713F-HRTimeline
LPL Financial LLC16,542$9.63M<0.01%-5,99613F-HRTimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.16,325$9.51M0.02%+12,44013F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …16,052$9.36M0.01%-1,27513F-HRTimelineGroup
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC15,372$8.95M<0.01%+80613F-HRTimelineGroup
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …15,347$8.94M0.01%+15,21013F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc15,231$8.87M<0.01%-6,44013F-HRTimelineGroup
Man Group plcin group Man Group plc14,764$8.6M0.02%-6,56413F-HRTimelineGroup
CASTLEARK MANAGEMENT LLC14,466$8.42M0.25%+4,54013F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…14,008$8.16M0.01%+11713F-HRTimeline
Skandinaviska Enskilda Banken AB (publ)13,450$7.84M0.03%-4,91313F-HRTimeline
Informed Momentum Co LLC12,837$7.48M0.83%+1,99313F-HRTimeline
JOURNEY STRATEGIC WEALTH LLC12,829$7.47M0.2%+113F-HRTimeline
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…12,100$7.05M0.07%-7913F-HRTimelineGroup
IMC-Chicago, LLC12,051$7.02M0.12%new13F-HRTimeline
Nan Fung Group Holdings Ltd11,872$6.91M6.19%013F-HRTimeline
NOMURA ASSET MANAGEMENT CO LTDgroup of 2 filers holding11,592$6.75M+11,592Timeline
Voleon Capital Management LP11,235$6.54M0.14%new13F-HRTimeline
Creative Planningin group Creative Planning11,141$6.49M<0.01%+2,71113F-HRTimelineGroup
Resolute Capital Asset Partners LLC10,918$6.36M3.07%-4,08213F-HRTimeline
Rafferty Asset Management, LLC10,530$6.13M0.02%-8,18513F-HRTimeline
EFG International AGin group EFG International AG10,373$6.05M0.12%13F-HRTimelineGroup
TD Asset Management Inc10,386$6.05M<0.01%-2,93813F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…10,237$5.96M0.03%-57013F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA10,223$5.95M<0.01%-9,95013F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC10,006$5.83M<0.01%+3,42013F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD9,276$5.4M0.01%-1,59913F-HRTimeline
ALGERT GLOBAL LLC8,970$5.22M0.08%+94013F-HR/ATimeline
Verition Fund Management LLC8,893$5.18M0.03%+3,26313F-HRTimeline
Engineers Gate Manager LP8,708$5.07M0.06%+5,77413F-HRTimeline
Hennion & Walsh Asset Management, Inc.8,163$4.75M0.16%-4,68413F-HRTimeline
Trexquant Investment LP7,784$4.53M0.04%new13F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC7,301$4.25M0.04%+63113F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCgroup of 2 filers holding7,261$4.23M-4,878Timeline
PFM Health Sciences, LP7,258$4.23M0.43%new13F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC6,978$4.06M<0.01%+5,18013F-HRTimelineGroup
Entropy Technologies, LP6,942$4.04M0.22%+3,24013F-HRTimeline
Capricorn Fund Managers Ltd6,600$3.84M0.93%new13F-HRTimeline
Calamos Advisors LLCin group Calamos Advisors LLC6,566$3.82M0.02%+2,08113F-HRTimelineGroup
SG Americas Securities, LLC6,386$3.72M<0.01%+1,19513F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC5,822$3.39M<0.01%+5913F-HRTimeline
F/m Investments LLC5,738$3.34M0.13%-58413F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC5,675$3.3M<0.01%-23813F-HRTimelineGroup
Assenagon Asset Management S.A.5,390$3.14M<0.01%new13F-HRTimeline
Orion Porfolio Solutions, LLC5,350$3.12M0.02%+1,25913F-HRTimeline
TUDOR INVESTMENT CORP ET AL5,285$3.08M0.02%+4,35913F-HRTimeline
Fieldview Capital Management, LLC5,196$3.03M0.51%+53813F-HRTimeline
Handelsbanken Fonder AB5,080$2.96M0.01%+68013F-HRTimeline
O'Neil Global Advisors, Inc.5,060$2.95M1.01%new13F-HRTimeline
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…5,044$2.94M0.01%-18113F-HRTimelineGroup
Police & Firemen's Retirement System of…5,016$2.92M0.02%-14913F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC4,810$2.8M0.01%-24813F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…4,759$2.77M<0.01%+15013F-HRTimeline
Pathstone Holdings, LLCin group Pathstone Holdings, LLC4,733$2.76M0.01%+2,29713F-HRTimelineGroup
PEAK FINANCIAL ADVISORS LLC4,466$2.6M1.17%+3,31213F-HRTimeline
ProShare Advisors LLC4,449$2.59M<0.01%+47513F-HRTimeline
HRT FINANCIAL LP4,218$2.46M0.01%new13F-HRTimeline
PROFUND ADVISORS LLC4,157$2.42M0.07%-4513F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC5,603$2.4M0.01%+47913F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM4,040$2.35M0.01%-21513F-HRTimeline
SHIKIAR ASSET MANAGEMENT INC4,000$2.33M0.58%013F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC3,958$2.3M<0.01%new13F-HRTimelineGroup
Cetera Investment Advisers3,941$2.3M<0.01%+21513F-HRTimeline
Moody Aldrich Partners LLC3,876$2.26M0.42%new13F-HRTimeline
DekaBank Deutsche Girozentrale8,000$2.25M<0.01%013F-HRTimeline
Knights of Columbus Asset Advisors LLC3,702$2.16M0.12%-14613F-HRTimeline
China Universal Asset Management Co., L…3,701$2.16M0.17%-20613F-HRTimeline
Cinctive Capital Management LP3,687$2.15M0.12%+8113F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…3,632$2.12M0.04%+2,25713F-HRTimelineGroup
Allworth Financial LP3,558$2.07M0.01%+1013F-HRTimeline
NFSG Corp3,548$2.07M0.32%-9413F-HRTimeline
MARTINGALE ASSET MANAGEMENT L P3,386$1.97M0.05%-1,12913F-HRTimeline
FARALLON CAPITAL MANAGEMENT, L.L.C.3,319$1.93M0.01%013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
STRS OHIO3,300$1.92M0.01%+1,10013F-HRTimeline
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.3,300$1.92M0.4%new13F-HRTimelineGroup
KLP KAPITALFORVALTNING AS3,240$1.89M0.01%+24013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.3,050$1.78M<0.01%+2,24813F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…2,978$1.73M<0.01%+85513F-HRTimeline
Penn Capital Management Company, LLC2,902$1.72M0.14%new13F-HRTimeline
Bellevue Group AGin group Bellevue Group AG2,884$1.68M0.03%+49113F-HRTimelineGroup
TEACHERS RETIREMENT SYSTEM OF THE STATE…2,872$1.67M0.01%013F-HRTimeline
Dana Investment Advisors, Inc.2,866$1.67M0.05%-31513F-HRTimeline
HighVista Strategies LLC2,839$1.65M0.43%-69813F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd2,819$1.64M0.04%new13F-HRTimelineGroup
AMI ASSET MANAGEMENT CORP2,752$1.6M0.09%-67413F-HRTimeline
Aigen Investment Management, LP2,652$1.54M0.36%+2,06713F-HRTimeline
QUADRANT CAPITAL GROUP LLC2,605$1.52M0.05%013F-HRTimeline
BAMCO INC /NY/in group Baron Capital2,500$1.46M<0.01%-10013F-HRTimelineGroup
Strid Group, LLC2,500$1.46M0.18%013F-HRTimeline
Mariner, LLCin group Mariner, LLC2,426$1.41M<0.01%+60513F-HRTimelineGroup
Allianz Asset Management GmbHin group Allianz SE2,400$1.4M<0.01%-70013F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC2,342$1.36M<0.01%-13513F-HRTimeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP2,327$1.36M<0.01%-28213F-HRTimelineGroup
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.2,300$1.34M0.01%new13F-HRTimelineGroup
Inspire Investing, LLCin group Inspire Investing, LLC2,256$1.31M0.12%new13F-HRTimelineGroup
Snowden Capital Advisors LLC2,225$1.3M0.03%-28513F-HRTimeline
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC2,161$1.26M0.01%+53613F-HRTimelineGroup
TEACHER RETIREMENT SYSTEM OF TEXAS2,151$1.25M<0.01%-1,38013F-HRTimeline
D.A. DAVIDSON & CO.2,129$1.24M0.01%+5813F-HRTimeline
Kestra Advisory Services, LLCgroup of 2 filers holding2,025$1.18M+16Timeline
TOTH FINANCIAL ADVISORY CORP2,000$1.16M0.13%new13F-HRTimeline
Knott David M Jr2,000$1.16M0.54%013F-HRTimeline
FORA Capital, LLC1,997$1.16M0.14%-50613F-HRTimeline
Illinois Municipal Retirement Fund1,903$1.11M0.01%new13F-HRTimeline
CWM, LLCin group CWM, LLC1,875$1.09M<0.01%-48513F-HRTimelineGroup
Seven Fleet Capital Management LP1,860$1.08M0.73%13F-HR/ATimeline
OPPENHEIMER ASSET MANAGEMENT INC.group of 2 filers holding1,705$993K+599Timeline