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Disclosery

MDGL MADRIGAL PHARMACEUTICALS INC

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Stock (common), issuer CIK 1157601

345 managers (353 13F filers) reported a position in MDGL shares at 2025-09-30, 23,389,191 shares in all. 84 filers opened a position and 37 filers sold out during the quarter.

Managers
345
13F filers
353
New
84
Added
107
Reduced
107
Sold out
37
Shares held by filers
23,389,191

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP2,141,701$982M7.1%+165,68313F-HRTimelineGroup
RTW INVESTMENTS, LP1,993,687$914M11.27%013F-HRTimeline
PAULSON & CO. INC.1,907,523$875M29.46%-182,00013F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson1,842,690$845M0.39%-349,06313F-HRTimelineGroup
Avoro Capital Advisors LLC1,833,000$841M10.88%-42,00013F-HRTimeline
VANGUARD GROUP INCgroup of 2 filers holding1,813,143$832M-65,122Timeline
BlackRock, Inc.in group BlackRock, Inc.1,559,712$715M0.01%+120,98813F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP658,097$302M0.01%-32,61813F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC446,233$205M0.01%+31,84113F-HRTimelineGroup
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC411,802$189M0.49%+61,51313F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…404,455$186M0.03%+397,07613F-HRTimelineGroup
FMR LLCin group FMR LLC401,136$184M0.01%-44,20313F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC386,100$177M0.03%+196,26013F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/352,520$162M0.02%-155,94413F-HRTimeline
Invesco Ltd.in group Invesco Ltd.299,565$137M0.02%+99,20913F-HRTimelineGroup
Polar Capital Holdings Plcin group Polar Capital Holdings Plc265,154$122M0.59%+39,74413F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY249,647$115M0.01%+1,68513F-HR/ATimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/244,292$112M0.01%-32,92913F-HR/ATimelineGroup
Hood River Capital Management LLC242,808$111M1.31%-1,93013F-HRTimeline
UBS Group AGgroup of 2 filers holding240,819$110M-304,704Timeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co213,652$98M0.02%+60,56713F-HRTimelineGroup
Artisan Partners Limited Partnership206,254$94.6M0.14%+4,68313F-HRTimeline
Erste Asset Management GmbHin group Erste Asset Management GmbH201,100$89.1M0.86%013F-HRTimelineGroup
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…191,796$87.7M0.08%-16,47013F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC165,615$76M0.04%-2,16913F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP159,988$73.4M0.01%+17,12013F-HRTimelineGroup
Rock Springs Capital Management LP137,746$63.2M3.69%-2,55013F-HRTimeline
Fiera Capital Corpin group Fiera Capital Corp127,800$58.6M0.19%-2,82213F-HRTimelineGroup
ArrowMark Colorado Holdings LLC123,259$56.5M1.05%-21,54913F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC120,682$55.4M0.07%+109,84613F-HRTimeline
ALKEON CAPITAL MANAGEMENT LLC120,000$55M0.25%new13F-HRTimeline
ARMISTICE CAPITAL, LLC119,982$55M1.73%-4,01813F-HRTimeline
Driehaus Capital Management LLC115,974$53.2M0.38%new13F-HRTimeline
Affinity Asset Advisors, LLC115,000$52.7M4.91%+35,00013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding111,068$50.9M+4,496Timeline
Woodline Partners LP103,847$47.6M0.22%-55,77613F-HRTimeline
LORD, ABBETT & CO. LLC102,143$46.8M0.14%+17,92613F-HRTimeline
MPM BIOIMPACT LLC100,415$46.1M7.54%013F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp97,779$44.8M0.01%+8,83613F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.96,182$44.1M0.04%-15,79913F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC95,734$43.9M0.05%new13F-HRTimelineGroup
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…88,500$40.6M0.06%-287,66313F-HRTimelineGroup
EMERALD ADVISERS, LLCgroup of 2 filers holding85,828$39.4M-4,200Timeline
Connor, Clark & Lunn Investment Managem…85,773$39.3M0.12%-14,32213F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management82,401$37.8M0.08%+47,90113F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources75,570$34.7M0.01%+14,85513F-HRTimelineGroup
EcoR1 Capital, LLC75,000$34.4M1.65%013F-HRTimeline
Nuveen, LLCin group TIAA73,715$33.8M0.01%+32,18213F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS70,757$32.5M0.03%+1,72013F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC70,584$32.4M0.01%+15,65113F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND69,273$31.8M0.04%+8,21113F-HRTimeline
Soleus Capital Management, L.P.68,336$31.3M1.68%+60,33613F-HRTimeline
Tri Locum Partners LP67,706$31.1M7.14%-30,05913F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding61,934$28.4M-21,114Timeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC59,437$27.3M0.03%+8,34713F-HRTimelineGroup
Iron Triangle Partners LP58,378$26.8M3.81%new13F-HRTimeline
Ensign Peak Advisors, Inc53,267$24.4M0.04%+4,86813F-HR/ATimeline
EULAV Asset Management51,000$23.4M0.54%+20,00013F-HRTimeline
Candriam S.C.A.49,965$22.9M0.12%013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC49,912$22.9M0.01%-12,76213F-HR/ATimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC48,372$22.2M0.02%-158,96713F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO47,824$21.9M<0.01%-8,03013F-HR/ATimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…44,885$20.6M0.02%+10,87013F-HRTimelineGroup
Rheos Capital Works Inc.43,215$19.8M1.11%013F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.41,233$18.9M0.04%-69,64413F-HRTimelineGroup
Tao Capital Management LP41,000$18.8M14.22%-71,78513F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN37,818$17.3M<0.01%+1,14913F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\37,342$17.1M0.01%+13,22713F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.35,695$16.4M0.01%+14,44513F-HRTimeline
Ally Bridge Group (NY) LLC32,662$15M12.54%new13F-HRTimeline
GILDER GAGNON HOWE & CO LLC30,848$14.1M0.14%-70513F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC29,936$13.7M0.03%+25,55413F-HRTimelineGroup
STEADFAST CAPITAL MANAGEMENT LP29,800$13.7M0.25%new13F-HRTimeline
Swiss National Bank27,900$12.8M0.01%+50013F-HRTimeline
Bridgewater Associates, LP27,785$12.7M0.05%new13F-HRTimeline
GROUPAMA ASSET MANAGMENT27,444$12.6M0.18%-13,44713F-HRTimeline
RHUMBLINE ADVISERS27,263$12.5M0.01%+90013F-HRTimeline
California Public Employees Retirement …24,097$11.1M0.01%-3,48613F-HRTimeline
LPL Financial LLC22,538$10.3M<0.01%+8,41713F-HRTimeline
SEGALL BRYANT & HAMILL, LLC22,490$10.3M0.14%new13F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc21,671$9.94M<0.01%-1,43813F-HRTimelineGroup
Man Group plcin group Man Group plc21,328$9.78M0.02%+19,96113F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC20,956$9.61M0.12%new13F-HR/ATimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA20,173$9.25M<0.01%+10,57013F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO19,115$8.77M0.01%+1,57313F-HRTimelineGroup
Rafferty Asset Management, LLC18,715$8.58M0.03%-5,81813F-HRTimeline
NEUBERGER BERMAN GROUP LLCin group NEUBERGER BERMAN GROUP LLC18,531$8.5M0.01%new13F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…18,451$8.46M0.02%+50313F-HRTimelineGroup
Skandinaviska Enskilda Banken AB (publ)18,363$8.44M0.03%+14,38513F-HRTimeline
Rhenman & Partners Asset Management AB18,250$8.37M0.93%new13F-HRTimeline
Cubist Systematic Strategies, LLC17,889$8.2M0.12%new13F-HRTimeline
WCM INVESTMENT MANAGEMENT, LLC18,291$8.1M0.02%new13F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …17,327$7.95M0.01%-6,08913F-HRTimelineGroup
SCHRODER INVESTMENT MANAGEMENT GROUP16,612$7.36M0.01%-16,59513F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …15,288$7.01M0.01%+12,15713F-HRTimelineGroup
AXA Investment Managers S.A.15,036$6.9M0.02%13F-HRTimeline
Resolute Capital Asset Partners LLC15,000$6.88M3.6%new13F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC14,566$6.68M<0.01%+6413F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…13,891$6.37M0.01%-24213F-HRTimeline
MACQUARIE GROUP LTDin group MACQUARIE GROUP LTD13,493$6.19M0.01%-6,15013F-HRTimelineGroup
TD Asset Management Inc13,324$6.11M<0.01%-9,91613F-HRTimeline
University of Wisconsin Foundation13,007$5.97M5.05%-35,36913F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC12,997$5.96M<0.01%+4,59113F-HRTimelineGroup
Hennion & Walsh Asset Management, Inc.12,847$5.89M0.21%+17213F-HRTimeline
JOURNEY STRATEGIC WEALTH LLC12,828$5.88M0.17%-25013F-HRTimeline
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…12,179$5.59M0.06%-13013F-HRTimelineGroup
PRINCIPAL FINANCIAL GROUP INCgroup of 2 filers holding12,139$5.57M+2,857Timeline
Nan Fung Group Holdings Ltd11,872$5.45M9.13%013F-HRTimeline
First Light Asset Management, LLC11,539$5.29M0.5%new13F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD10,875$4.99M0.01%+1,88113F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…10,807$4.96M0.02%+74513F-HRTimelineGroup
Informed Momentum Co LLC10,844$4.89M0.56%new13F-HRTimeline
CASTLEARK MANAGEMENT LLC9,926$4.55M0.13%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC9,648$4.43M<0.01%-8,83513F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD9,000$4.13M<0.01%+3,60013F-HRTimeline
Creative Planningin group Creative Planning8,430$3.87M<0.01%+3,26813F-HRTimelineGroup
EFG Asset Management (North America) Co…8,294$3.81M0.49%new13F-HRTimeline
STEMPOINT CAPITAL LP8,207$3.76M0.76%-44,48713F-HRTimeline
ALGERT GLOBAL LLC8,030$3.68M0.06%-1,50013F-HR/ATimeline
DekaBank Deutsche Girozentrale8,000$3.51M0.01%013F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC6,670$3.06M0.03%-2,39313F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC6,586$3.02M<0.01%+3,41913F-HRTimelineGroup
F/m Investments LLC6,322$2.9M0.11%+26513F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC5,913$2.71M<0.01%+78313F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP5,799$2.66M<0.01%+1,92913F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC5,763$2.64M<0.01%-2,51813F-HRTimeline
Verition Fund Management LLC5,630$2.58M0.01%+1,31013F-HRTimeline
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…5,225$2.4M0.01%-1,66513F-HRTimelineGroup
SG Americas Securities, LLC5,191$2.38M0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…5,165$2.37M0.02%+1,32213F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC5,124$2.35M0.01%-2513F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC5,058$2.32M<0.01%+16013F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC4,895$2.25M0.22%+3,84113F-HRTimelineGroup
WOLVERINE TRADING, LLC5,056$2.24M0.05%+4,08413F-HRTimeline
Fieldview Capital Management, LLC4,658$2.14M0.35%new13F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…4,609$2.11M<0.01%-76813F-HRTimeline
MARTINGALE ASSET MANAGEMENT L P4,515$2.07M0.05%-93013F-HRTimeline
Calamos Advisors LLCin group Calamos Advisors LLC4,485$2.06M0.01%new13F-HRTimelineGroup
Handelsbanken Fonder AB4,400$2.02M0.01%013F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM4,255$1.95M0.01%+7813F-HRTimeline
PROFUND ADVISORS LLC4,202$1.93M0.06%-98813F-HRTimeline
Orion Porfolio Solutions, LLC4,091$1.88M0.01%+45313F-HRTimeline
SHIKIAR ASSET MANAGEMENT INC4,000$1.83M0.46%-1,00013F-HRTimeline
ProShare Advisors LLC3,974$1.82M<0.01%-31713F-HRTimeline
China Universal Asset Management Co., L…3,907$1.79M0.15%-55213F-HRTimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.3,885$1.78M<0.01%new13F-HRTimelineGroup
Knights of Columbus Asset Advisors LLC3,848$1.76M0.1%-75513F-HRTimeline
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP3,795$1.74M<0.01%+2,04913F-HRTimelineGroup
Cetera Investment Advisers3,726$1.71M<0.01%+1,86613F-HRTimeline
Entropy Technologies, LP3,702$1.7M0.13%+1,80013F-HRTimeline
NFSG Corp3,642$1.67M0.25%+6613F-HRTimeline
Cinctive Capital Management LP3,606$1.65M0.08%-1,16213F-HRTimeline
Allworth Financial LP3,548$1.63M0.01%+1413F-HRTimeline
HighVista Strategies LLC3,537$1.62M0.4%+1,23213F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS3,531$1.62M0.01%-32913F-HRTimeline
AMI ASSET MANAGEMENT CORP3,426$1.57M0.09%-1413F-HRTimeline
FARALLON CAPITAL MANAGEMENT, L.L.C.3,319$1.52M0.01%013F-HR/ATimeline
Dana Investment Advisors, Inc.3,181$1.46M0.04%+29813F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE3,100$1.42M<0.01%+1,60013F-HRTimelineGroup
KLP KAPITALFORVALTNING AS3,000$1.38M0.01%013F-HRTimeline
Engineers Gate Manager LP2,934$1.35M0.02%-1,48913F-HRTimeline
TEACHERS RETIREMENT SYSTEM OF THE STATE…2,872$1.32M0.01%new13F-HRTimeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP2,609$1.2M<0.01%-56513F-HRTimelineGroup
QUADRANT CAPITAL GROUP LLC2,605$1.19M0.04%013F-HRTimeline
BAMCO INC /NY/in group Baron Capital2,600$1.19M<0.01%new13F-HRTimelineGroup
Qube Research & Technologies Ltd2,588$1.19M<0.01%-1,25613F-HRTimeline
Snowden Capital Advisors LLC2,510$1.15M0.03%+39213F-HRTimeline
FORA Capital, LLC2,503$1.15M0.2%new13F-HRTimeline
Strid Group, LLC2,500$1.15M0.15%013F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC2,477$1.14M<0.01%+63013F-HRTimeline
First National Trust Co2,476$1.14M0.04%-5,53813F-HRTimeline
Pathstone Holdings, LLCin group Pathstone Holdings, LLC2,436$1.12M<0.01%new13F-HRTimelineGroup
J. Safra Sarasin Holding AGin group J. Safra Sarasin Holding AG2,397$1.1M0.02%-4,42613F-HRTimelineGroup
Bellevue Group AGin group Bellevue Group AG2,393$1.1M0.02%+1,29313F-HRTimelineGroup
CWM, LLCin group CWM, LLC2,360$1.08M<0.01%-22013F-HRTimelineGroup
FOX RUN MANAGEMENT, L.L.C.2,318$1.06M0.17%new13F-HRTimeline
Tidal Investments LLCin group Tidal Investments LLC2,209$1.01M<0.01%new13F-HRTimelineGroup
STRS OHIO2,200$1.01M<0.01%+80013F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…2,123$974K<0.01%-1113F-HRTimeline
D.A. DAVIDSON & CO.2,071$950K0.01%+51813F-HRTimeline
CIBC Bancorp USA Inc.group of 2 filers holding2,034$933KnewTimeline
Kestra Advisory Services, LLCgroup of 2 filers holding2,009$921K+64Timeline
Sigma Planning Corp2,000$917K0.03%new13F-HRTimeline
Knott David M Jr2,000$917K0.38%013F-HRTimeline
Baader Bank Aktiengesellschaft1,935$885K0.07%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
Mariner, LLCin group Mariner, LLC1,821$835K<0.01%+27113F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC1,798$825K<0.01%-9,03713F-HRTimelineGroup
GSA CAPITAL PARTNERS LLP1,739$798K0.07%new13F-HRTimeline
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC1,625$745K0.01%-41313F-HRTimelineGroup
NEOS Investment Management LLC1,621$743K0.01%-18013F-HRTimeline
Tema ETFs LLC1,621$743K0.06%-18013F-HRTimeline
R Squared Ltd1,619$743K0.32%-15113F-HRTimeline
New York Life Investment Management LLCin group New York Life Investment Mana…1,610$738K0.01%-4313F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…1,554$713K0.02%-17013F-HRTimelineGroup
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co1,608$711K<0.01%013F-HRTimelineGroup
NJ State Employees Deferred Compensatio…1,500$688K0.08%013F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…1,495$686K0.2%013F-HRTimelineGroup
AlTi Global, Inc.in group AlTi Global, Inc.1,492$684K0.02%013F-HRTimelineGroup
Sanctuary Advisors, LLC1,465$672K<0.01%+19213F-HR/ATimeline
XPONANCE LLC1,460$670K0.01%+15213F-HRTimeline