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Disclosery

MBX MBX BIOSCIENCES INC

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Stock (common), issuer CIK 1776111

118 managers (118 13F filers) reported a position in MBX shares at 2025-09-30, 47,790,067 shares in all. 39 filers opened a position and 9 filers sold out during the quarter.

Managers
118
13F filers
118
New
39
Added
29
Reduced
30
Sold out
9
Shares held by filers
47,790,067

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Frazier Life Sciences Management, L.P.6,652,013$116M3.49%+666,66613F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…4,823,336$84.4M0.01%+2,556,70813F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC4,002,887$70.1M1.68%013F-HRTimelineGroup
NEA Management Company, LLC3,614,486$63.3M3.47%013F-HRTimeline
Deep Track Capital, LP3,150,000$55.1M1.54%+961,40813F-HRTimeline
NVP ASSOCIATES, LLC2,136,335$37.4M22.51%013F-HRTimeline
EcoR1 Capital, LLC2,123,604$37.2M1.78%+973,81013F-HRTimeline
Kynam Capital Management, LP2,000,000$35M2.61%new13F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.1,957,461$34.3M<0.01%+945,91513F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC1,677,362$29.4M<0.01%+633,67813F-HRTimelineGroup
Driehaus Capital Management LLC1,539,639$26.9M0.19%-32,26713F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources1,307,288$22.9M0.01%+812,43613F-HRTimelineGroup
Cormorant Asset Management, LP1,225,000$21.4M1.48%+525,00013F-HRTimeline
Woodline Partners LP1,201,150$21M0.1%+300,04713F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC996,083$17.4M0.01%new13F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/954,726$16.7M<0.01%-392,18413F-HRTimeline
Parkman Healthcare Partners LLC773,304$13.5M1.49%-98,62913F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC655,416$11.5M0.01%-111,42413F-HRTimelineGroup
TCG Crossover Management, LLC650,000$11.4M0.56%013F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.627,667$11M0.02%-346,12013F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC473,932$8.3M<0.01%+125,48513F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC358,121$6.27M<0.01%new13F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP319,274$5.59M<0.01%+54,15513F-HRTimelineGroup
Schonfeld Strategic Advisors LLC282,677$4.95M0.03%-348,73613F-HRTimeline
Rock Springs Capital Management LP282,624$4.95M0.29%new13F-HRTimeline
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP277,777$4.86M0.04%new13F-HRTimelineGroup
Soleus Capital Management, L.P.275,000$4.81M0.26%new13F-HRTimeline
Opaleye Management Inc.253,000$4.43M0.63%+13,68113F-HRTimeline
Longaeva Partners L.P.224,433$3.93M0.84%new13F-HRTimeline
PFM Health Sciences, LP221,505$3.88M0.33%new13F-HRTimeline
SECTORAL ASSET MANAGEMENT INC194,898$3.41M2.11%+3,07313F-HRTimeline
Tetragon Partners GP Ltdin group Tetragon Partners GP Ltd177,840$3.11M0.45%new13F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co170,006$2.98M<0.01%+62,52313F-HRTimelineGroup
Affinity Asset Advisors, LLC165,000$2.89M0.27%new13F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP133,265$2.33M<0.01%+17,67113F-HRTimelineGroup
TD Asset Management Inc118,792$2.08M<0.01%-52,51213F-HRTimeline
ExodusPoint Capital Management, LP100,000$1.75M0.02%new13F-HRTimeline
Burkehill Global Management, LP100,000$1.75M0.1%new13F-HRTimeline
SCHRODER INVESTMENT MANAGEMENT GROUP83,766$1.5M<0.01%new13F-HRTimeline
DAFNA Capital Management LLC85,000$1.49M0.37%new13F-HRTimeline
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…85,000$1.49M0.01%new13F-HR/ATimelineGroup
Murchinson Ltd.80,000$1.4M0.27%new13F-HRTimeline
STEMPOINT CAPITAL LP75,000$1.31M0.26%-66,02113F-HRTimeline
PLATINUM INVESTMENT MANAGEMENT LTD69,428$1.21M0.08%-43,31513F-HRTimeline
FMR LLCin group FMR LLC68,976$1.21M<0.01%+7,64313F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …68,376$1.2M<0.01%-18,72113F-HRTimelineGroup
UBS Group AGin group UBS Group AG60,725$1.06M<0.01%+29,75813F-HRTimelineGroup
Exome Asset Management LLC52,402$917K0.61%-10,67413F-HRTimeline
Aaron Wealth Advisors LLC50,000$875K0.05%013F-HRTimeline
Ikarian Capital, LLCin group Ikarian Capital, LLC48,071$841K0.17%new13F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp47,735$835K<0.01%+9,70313F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY44,868$785K<0.01%+20,86013F-HR/ATimelineGroup
BOOTHBAY FUND MANAGEMENT, LLC39,498$691K0.02%new13F-HRTimeline
READYSTATE ASSET MANAGEMENT LP38,500$674K0.03%new13F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd38,378$672K0.03%+26,51713F-HRTimelineGroup
Ghisallo Capital Management LLC38,250$669K0.02%new13F-HRTimeline
Weiss Asset Management LPin group Weiss Asset Management LP30,823$539K0.01%new13F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
SummitTX Capital, L.P.29,310$513K0.02%new13F-HRTimeline
Creative Planningin group Creative Planning28,732$503K<0.01%new13F-HRTimelineGroup
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …28,461$498K<0.01%new13F-HRTimelineGroup
Koa Wealth Management, LLC26,713$467K0.35%-5,03913F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/26,616$466K<0.01%-15,77113F-HR/ATimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management25,641$449K<0.01%new13F-HRTimelineGroup
Nuveen, LLCin group TIAA22,143$388K<0.01%013F-HRTimelineGroup
RHUMBLINE ADVISERS21,821$382K<0.01%-1,84113F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC21,626$378K<0.01%-36,91513F-HR/ATimelineGroup
Caption Management, LLC20,000$350K0.02%new13F-HRTimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC16,840$295K<0.01%-1,20813F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC15,764$276K<0.01%-2,23713F-HRTimelineGroup
Walleye Capital LLCin group Walleye Capital LLC15,176$266K<0.01%-55,15713F-HRTimelineGroup
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…15,000$262K0.04%new13F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC14,200$248K0.01%-15,00013F-HRTimeline
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP13,587$238K<0.01%new13F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.11,788$206K<0.01%new13F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN11,755$206K<0.01%+81213F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…11,018$193K<0.01%013F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\10,923$191K<0.01%+2,16113F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…10,614$186K0.05%+1,84213F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.10,500$184K<0.01%013F-HRTimeline
Man Group plcin group Man Group plc10,225$179K<0.01%new13F-HRTimelineGroup
Symmetry Investments LPin group Symmetry Investments LP10,000$175K0.01%new13F-HRTimelineGroup
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…7,120$125K<0.01%-2,20913F-HRTimelineGroup
Quarry LP6,499$114K0.03%-1,50113F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO6,175$108K<0.01%-2,00913F-HR/ATimelineGroup
China Universal Asset Management Co., L…5,000$87.5K0.01%new13F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC5,009$86K<0.01%new13F-HRTimelineGroup
Police & Firemen's Retirement System of…4,509$78.9K<0.01%+2,36613F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND4,300$75.2K<0.01%013F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…3,000$52.5K<0.01%-31,13513F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS2,896$50.7K<0.01%+1,56713F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC1,592$27.9K<0.01%013F-HRTimeline
FNY Investment Advisers, LLC1,575$27K0.01%new13F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…1,481$25.9K<0.01%+1,44613F-HRTimelineGroup
CWM, LLCin group CWM, LLC1,384$24K<0.01%-41813F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc1,328$23.2K<0.01%-22313F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,267$22.2K<0.01%-84313F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…1,177$20.6K<0.01%013F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…1,065$18.6K<0.01%+113F-HRTimeline
Sterling Capital Management LLC1,058$18.5K<0.01%+59813F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA960$17K<0.01%-33813F-HRTimelineGroup
STRS OHIO700$12.2K<0.01%013F-HRTimeline
AMALGAMATED BANK384$7K<0.01%013F-HRTimeline
Arax Advisory Partners398$6.96K<0.01%new13F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\337$5.9K<0.01%013F-HRTimelineGroup
Farther Finance Advisors, LLC328$5.74K<0.01%new13F-HRTimeline
GAMMA Investing LLC299$5.23K<0.01%013F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…252$4.41K<0.01%new13F-HRTimelineGroup
SIGNATUREFD, LLC179$3.13K<0.01%+7813F-HRTimeline
CITIGROUP INCin group CITIGROUP INC178$3.12K<0.01%-5,54513F-HRTimelineGroup
Physician Wealth Advisors, Inc.109$1.91K<0.01%013F-HRTimeline
Washington Trust Advisors, Inc.83$1.45K<0.01%new13F-HRTimeline
COMERICA BANK76$1.33K<0.01%new13F-HRTimeline
Rise Advisors, LLC68$1.19K<0.01%013F-HRTimeline
Parallel Advisors, LLC61$1.07K<0.01%-4713F-HRTimeline
Allworth Financial LP25$438<0.01%013F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…23$403<0.01%-613F-HRTimelineGroup
ROTHSCHILD INVESTMENT LLC20$350<0.01%013F-HRTimeline
Essential Partners LLC2$35<0.01%013F-HRTimeline