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Disclosery

MBX MBX BIOSCIENCES INC

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Stock (common), issuer CIK 1776111

150 managers (157 13F filers) reported a position in MBX shares at 2026-03-31, 52,535,823 shares in all. 33 filers opened a position and 18 filers sold out during the quarter.

Managers
150
13F filers
157
New
33
Added
43
Reduced
47
Sold out
18
Shares held by filers
52,535,823

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2026

Filers in the available 13F reports with a share position at 2026-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Frazier Life Sciences Management, L.P.6,652,013$199M5.11%013F-HRTimeline
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC3,637,887$109M2.37%-297,31613F-HRTimelineGroup
NEA Management Company, LLC3,614,486$108M6.13%013F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…3,191,824$95.3M0.02%-158,13713F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.2,941,406$87.8M<0.01%+21,65013F-HRTimelineGroup
FMR LLCin group FMR LLC2,936,684$87.7M<0.01%+2,920,93813F-HRTimelineGroup
Deep Track Capital, LP2,757,569$82.3M1.7%-492,22113F-HRTimeline
NVP ASSOCIATES, LLC2,136,335$63.8M36.2%013F-HRTimeline
VANGUARD GROUP INCgroup of 6 filers holding1,977,924$59MnewTimeline
Polar Capital Holdings Plcin group Polar Capital Holdings Plc1,622,186$48.4M0.21%new13F-HRTimelineGroup
BRAIDWELL LP1,492,467$44.6M1.49%+473,86713F-HRTimeline
Aaron Wealth Advisors LLC1,168,176$34.9M2.01%+1,098,17613F-HRTimeline
Cormorant Asset Management, LP1,120,000$33.4M1.69%013F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/1,029,007$30.7M<0.01%+188,50113F-HRTimeline
Driehaus Capital Management LLC1,018,212$30.4M0.22%-389,94713F-HRTimeline
Kynam Capital Management, LP934,799$27.9M1.77%013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC932,833$27.8M0.02%+122,97613F-HRTimelineGroup
Woodline Partners LP900,063$26.9M0.1%-100,00013F-HR/ATimeline
EVENTIDE ASSET MANAGEMENT, LLC890,000$26.6M0.44%013F-HRTimeline
Caligan Partners LP848,590$25.3M1.79%new13F-HRTimeline
Parkman Healthcare Partners LLC800,037$23.9M2.48%-85,60213F-HRTimeline
STATE STREET CORPin group STATE STREET CORP787,208$23.5M<0.01%+114,46813F-HRTimelineGroup
EcoR1 Capital, LLC777,000$23.2M0.99%-1,346,60413F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC670,385$20M<0.01%+20,99413F-HRTimelineGroup
TCG Crossover Management, LLC650,000$19.4M0.56%013F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC564,415$16.8M0.01%+102,36613F-HRTimelineGroup
STEMPOINT CAPITAL LP499,469$14.9M2.87%+420,91613F-HR/ATimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC457,945$13.7M<0.01%+126,00713F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding354,152$10.6M+72,840Timeline
Candriam S.C.A.294,374$8.79M0.05%new13F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.288,889$8.62M0.01%-382,94913F-HRTimelineGroup
Rock Springs Capital Management LP287,967$8.6M0.51%+5,34313F-HRTimeline
Opaleye Management Inc.260,000$7.76M1.02%013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co214,908$6.42M<0.01%-7,27213F-HRTimelineGroup
Elmind Capital, LP211,000$6.3M1.79%013F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP210,575$6.29M<0.01%+19,69413F-HRTimelineGroup
BOOTHBAY FUND MANAGEMENT, LLC208,049$6.21M0.14%new13F-HRTimeline
Soleus Capital Management, L.P.178,897$5.34M0.22%-230,00313F-HRTimeline
DAFNA Capital Management LLC175,465$5.24M1.19%+10,20013F-HRTimeline
Goelzer Investment Management, Inc.164,172$4.9M0.24%-57,50013F-HRTimeline
Affinity Asset Advisors, LLC150,000$4.48M0.26%-100,00013F-HRTimeline
Tetragon Partners GP Ltdin group Tetragon Partners GP Ltd145,480$4.34M0.85%+2,15313F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO147,057$3.96M<0.01%+132,41213F-HR/ATimelineGroup
Schonfeld Strategic Advisors LLC123,814$3.7M0.03%-43,31113F-HRTimeline
KVP Capital Advisors, LP121,524$3.63M2.71%013F-HRTimeline
TD Asset Management Inc115,998$3.46M<0.01%+14,54813F-HRTimeline
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP115,075$3.43M<0.01%-23,49613F-HRTimelineGroup
Burkehill Global Management, LP100,000$2.98M0.15%013F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC97,215$2.9M0.01%+50,51313F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …90,634$2.71M<0.01%+21,08313F-HRTimelineGroup
Nuveen, LLCin group TIAA81,792$2.44M<0.01%+6,22713F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp80,222$2.39M<0.01%+4,96013F-HRTimelineGroup
PFM Health Sciences, LP71,894$2.15M0.23%-7,41613F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC71,028$2.12M<0.01%new13F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP62,703$1.87M<0.01%new13F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd53,210$1.59M0.03%+33,07113F-HRTimelineGroup
SCHRODER INVESTMENT MANAGEMENT GROUP57,322$1.54M<0.01%-16,41413F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP46,753$1.4M<0.01%new13F-HRTimelineGroup
Swiss National Bank44,400$1.33M<0.01%new13F-HRTimeline
PLATINUM INVESTMENT MANAGEMENT LTD43,597$1.3M0.33%013F-HRTimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC36,550$1.09M0.01%-32213F-HRTimelineGroup
ALGERT GLOBAL LLC36,020$1.08M0.02%new13F-HR/ATimeline
Creative Planningin group Creative Planning35,970$1.07M<0.01%+2,31913F-HRTimelineGroup
EXCHANGE TRADED CONCEPTS, LLC34,264$1.02M0.01%new13F-HRTimeline
RHUMBLINE ADVISERS33,871$1.01M<0.01%+45113F-HRTimeline
ALLIANCEBERNSTEIN L.P.30,500$962K<0.01%+2,60013F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY31,562$942K<0.01%-27,46413F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/28,750$858K<0.01%-9,14413F-HRTimelineGroup
ExodusPoint Capital Management, LP28,087$838K0.01%-28,91813F-HRTimeline
Invesco Ltd.in group Invesco Ltd.27,525$822K<0.01%+6,32213F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC27,387$818K<0.01%-4,02213F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\22,950$685K<0.01%+2,92313F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…22,765$680K<0.01%+21,01113F-HRTimeline
Swiss Life Asset Management Ltdin group Swiss Life Asset Management L…12,130$657K<0.01%new13F-HRTimelineGroup
Cerity Partners LLCin group Cerity Partners LLC21,163$632K<0.01%-16013F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc19,358$578K<0.01%+16,81913F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD19,262$575K<0.01%new13F-HRTimeline
Koa Wealth Management, LLC17,913$535K0.39%-50013F-HRTimeline
Engineers Gate Manager LP17,380$519K0.01%new13F-HRTimeline
Qube Research & Technologies Ltd17,187$513K<0.01%-6,02613F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…16,018$478K<0.01%013F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding15,667$468K+227Timeline
OPTIMIZE FINANCIAL INC.14,508$433K0.21%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC13,499$403K<0.01%-2,89213F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC12,700$379K0.01%new13F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC11,838$353K<0.01%-40,85313F-HRTimelineGroup
HighVista Strategies LLC11,472$342K0.09%new13F-HRTimeline
CANADA PENSION PLAN INVESTMENT BOARD10,900$325K<0.01%-70013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN10,762$321K<0.01%-21,16913F-HR/ATimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS10,384$310K<0.01%+3,60013F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson10,300$308K<0.01%new13F-HR/ATimelineGroup
Verition Fund Management LLC10,222$305K<0.01%-47,35313F-HRTimeline
Aquatic Capital Management LLC10,155$303K0.01%new13F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…9,487$283K<0.01%-67,04113F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…9,131$273K0.08%+22113F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND9,000$269K<0.01%+4,70013F-HRTimeline
ACT CAPITAL MANAGEMENT, LLC9,000$269K0.21%new13F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO8,989$268K<0.01%+1,33213F-HRTimelineGroup
Tidal Investments LLCin group Tidal Investments LLC8,877$265K<0.01%new13F-HRTimelineGroup
Tema ETFs LLC8,877$265K0.02%new13F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC8,823$262K<0.01%-39,79113F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC8,726$260K<0.01%-3,51013F-HRTimelineGroup
PROFUND ADVISORS LLC8,388$250K0.01%-82613F-HRTimeline
China Universal Asset Management Co., L…7,968$238K0.02%-7,34913F-HRTimeline
Orion Porfolio Solutions, LLC7,951$237K<0.01%new13F-HRTimeline
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…7,673$229K<0.01%new13F-HRTimelineGroup
Police & Firemen's Retirement System of…7,520$224K<0.01%013F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC7,500$224K<0.01%-2,50013F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC6,844$204K<0.01%-1413F-HRTimeline
GROUP ONE TRADING LLC6,251$187K0.01%-3,17713F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC5,600$167K<0.01%-4,76013F-HRTimeline
KLP KAPITALFORVALTNING AS4,900$146K<0.01%new13F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…3,856$115K<0.01%+1,00013F-HRTimelineGroup
SG Americas Securities, LLC3,386$101K<0.01%-1,37913F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…3,224$96.2K<0.01%+22413F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…2,312$69K<0.01%013F-HRTimelineGroup
Cygnus Capital Advisors, LLC1,800$54K0.04%013F-HRTimeline
CWM, LLCin group CWM, LLC1,772$52.9K<0.01%-1213F-HRTimelineGroup
STRS OHIO1,600$47.8K<0.01%+90013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC1,592$47.5K<0.01%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,411$42.1K<0.01%-2,00513F-HRTimelineGroup
SIMPLEX TRADING, LLC1,307$39K<0.01%-7,61813F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,009$30.1K<0.01%+12713F-HRTimeline
Sterling Capital Management LLC949$28.3K<0.01%-69213F-HRTimeline
KBC Group NVin group KBC Group NV810$24K<0.01%new13F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA751$22K<0.01%-78113F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…470$14K<0.01%new13F-HRTimeline
GAMMA Investing LLC299$8.93K<0.01%013F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\284$8.48K<0.01%-2813F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.269$8.03K<0.01%-77,33213F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…207$6.18K<0.01%+1113F-HRTimelineGroup
SIGNATUREFD, LLC179$5.34K<0.01%013F-HRTimeline
FIL Ltdin group FIL Ltd178$5.31K<0.01%new13F-HRTimelineGroup
Physician Wealth Advisors, Inc.109$3.25K<0.01%013F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP80$2.28K<0.01%013F-HRTimelineGroup
Allworth Financial LP70$2.09K<0.01%+1813F-HRTimeline
Parallel Advisors, LLC61$1.82K<0.01%013F-HR/ATimeline
Larson Financial Group LLC49$1.46K<0.01%new13F-HRTimeline
Cornerstone Financial Management LLC34$1.01K<0.01%013F-HR/ATimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…25$746<0.01%013F-HR/ATimelineGroup
ROTHSCHILD INVESTMENT LLC24$716<0.01%013F-HRTimeline
Versant Capital Management, Inc24$716<0.01%new13F-HRTimeline
Fortitude Family Office, LLC19$567<0.01%new13F-HRTimeline
Keating Financial Advisory Services, In…16$478<0.01%new13F-HRTimeline
Essential Partners LLC15$448<0.01%013F-HRTimeline
Farther Finance Advisors, LLC9$291<0.01%-113F-HRTimeline
MAI Capital Management7$209<0.01%new13F-HRTimeline
True Wealth Design, LLC2$60<0.01%013F-HRTimeline
IFP Advisors, Inc1$30<0.01%013F-HRTimeline
Covestor Ltd3$00%new13F-HRTimelineValue filed as zero, left out of ratios.