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Disclosery

KRYS KRYSTAL BIOTECH INC

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Stock (common), issuer CIK 1711279

356 managers (369 13F filers) reported a position in KRYS shares at 2026-03-31, 28,376,524 shares in all. 65 filers opened a position and 36 filers sold out during the quarter.

Managers
356
13F filers
369
New
65
Added
139
Reduced
105
Sold out
36
Shares held by filers
28,376,524

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2026

Filers in the available 13F reports with a share position at 2026-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC4,373,987$1.13B0.06%+24,35913F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.3,940,456$1.02B0.02%+2,63913F-HRTimelineGroup
Avoro Capital Advisors LLC2,888,888$746M7.35%013F-HRTimeline
VANGUARD GROUP INCgroup of 7 filers holding2,841,451$734M+2,839,324Timeline
STATE STREET CORPin group STATE STREET CORP1,314,434$340M0.01%-27,86913F-HRTimelineGroup
Soleus Capital Management, L.P.1,153,087$298M12.06%+212,02813F-HRTimeline
Capital World Investors824,720$213M0.03%+15,22013F-HRTimeline
Redmile Group, LLCin group Redmile Group, LLC673,505$174M11.52%-4,20013F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC643,975$166M0.01%+32,09713F-HRTimelineGroup
Hood River Capital Management LLC619,586$160M1.6%+6,28413F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/485,074$125M0.01%-44,88113F-HRTimeline
Bellevue Group AGin group Bellevue Group AG481,785$124M2.96%+71,46213F-HRTimelineGroup
Frazier Life Sciences Management, L.P.481,307$124M3.2%-7,15313F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP468,990$121M0.03%-23,97813F-HRTimelineGroup
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC407,178$105M0.35%+30,83813F-HRTimeline
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP350,521$90.5M0.06%+105,24513F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson266,659$68.9M0.03%+47,21913F-HR/ATimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/260,647$67.3M<0.01%+69,84013F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP252,463$65.2M0.01%+5,02013F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.251,373$64.9M0.01%+191,36513F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co241,986$62.5M0.01%-78813F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC214,949$55.5M0.01%-78,57613F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY209,082$54M<0.01%-12,39913F-HRTimelineGroup
BRAIDWELL LP182,425$47.1M1.57%-19,67613F-HRTimeline
UBS Group AGgroup of 2 filers holding180,462$46.6M-12,750Timeline
FRANKLIN RESOURCES INCin group Franklin Resources179,265$46.3M0.01%+53,59013F-HRTimelineGroup
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC162,070$41.9M0.02%-3,00413F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC156,064$39.5M0.01%+79,52613F-HRTimelineGroup
Woodline Partners LP150,616$38.9M0.15%013F-HR/ATimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp149,307$38.6M0.01%-2,00613F-HRTimelineGroup
Nuveen, LLCin group TIAA143,368$37M0.01%-45,72613F-HRTimelineGroup
TimesSquare Capital Management, LLC112,342$29M0.49%+14,94213F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…110,665$28.6M0.03%-45,90313F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC108,397$28M0.03%+5,13613F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO99,105$24.5M<0.01%-35,51913F-HR/ATimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS93,031$24M0.02%+39,12013F-HRTimelineGroup
Public Sector Pension Investment Board92,286$23.8M0.07%+2,92413F-HRTimeline
Handelsbanken Fonder AB91,400$23.6M0.08%-14,40013F-HRTimeline
S SQUARED TECHNOLOGY, LLC86,215$22.3M8.43%-10,00013F-HR/ATimeline
SEGALL BRYANT & HAMILL, LLC79,497$20.5M0.29%-3,74913F-HR/ATimeline
Biondo Investment Advisors, LLC72,045$18.6M2.39%+3,91513F-HRTimeline
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC69,100$17.8M0.39%-50,70013F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP68,343$17.7M0.02%-115,41113F-HRTimelineGroup
RHUMBLINE ADVISERS68,099$17.6M0.02%+1,66313F-HRTimeline
C WorldWide Group Holding A/Sin group C WorldWide Group Holding A/S67,809$17.5M0.38%-18,00013F-HRTimelineGroup
ACT CAPITAL MANAGEMENT, LLC60,477$15.6M12.28%-2313F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc59,050$15.3M<0.01%-4,31113F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC49,837$12.9M<0.01%-2,50813F-HR/ATimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO46,570$12M0.01%+14,26013F-HRTimelineGroup
Bridgewater Associates, LP46,367$12M0.05%+36,35213F-HRTimeline
SEB Asset Management AB46,343$12M0.05%13F-HRTimeline
Palisades Investment Partners, LLC45,405$11.7M4.6%+2,64013F-HRTimeline
TD Asset Management Inc43,318$11.2M0.01%-10,82413F-HRTimeline
Swiss National Bank43,000$11.1M0.01%+10013F-HRTimeline
1832 Asset Management L.P.42,600$11M0.01%+25,00013F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC40,715$10.5M0.01%+14,25413F-HRTimeline
GILDER GAGNON HOWE & CO LLC40,128$10.4M0.12%new13F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …36,069$9.32M0.01%-4,56013F-HRTimelineGroup
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…35,859$9.26M0.11%-1,41013F-HRTimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.35,495$9.17M0.01%+95413F-HRTimelineGroup
NEUBERGER BERMAN GROUP LLCin group NEUBERGER BERMAN GROUP LLC33,084$8.55M0.01%+32,05113F-HRTimelineGroup
CASTLEARK MANAGEMENT LLC31,630$8.17M0.27%+2,37013F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND31,342$8.1M0.01%013F-HRTimeline
CITIGROUP INCin group CITIGROUP INC31,172$8.05M0.01%+1,22913F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.31,929$7.87M<0.01%+40013F-HRTimeline
Aberdeen Group plcin group Aberdeen Group plc30,155$7.79M0.01%-9,20513F-HRTimelineGroup
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC29,638$7.66M0.01%+2,62313F-HRTimelineGroup
Fisher Asset Management, LLC27,784$7.18M<0.01%+23,99813F-HRTimeline
Atle Fund Management AB37,579$6.79M2.19%+3,72613F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…26,210$6.77M0.01%-2,74413F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…26,186$6.76M0.01%+5,60313F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\24,831$6.41M<0.01%+2,38113F-HRTimelineGroup
Granite Investment Partners, LLC24,284$6.27M0.39%-1,47613F-HRTimeline
Fiera Capital Corpin group Fiera Capital Corp24,146$6.24M0.02%+5,28913F-HRTimelineGroup
Elmind Capital, LP22,000$5.68M1.61%013F-HRTimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co21,413$5.53M0.01%-67413F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD20,691$5.34M0.01%+6,22513F-HRTimeline
BESSEMER GROUP INCin group BESSEMER GROUP INC20,285$5.24M0.01%+2513F-HRTimelineGroup
Pinnacle Financial Partners, Inc.in group Pinnacle Financial Partners, …20,180$5.21M0.04%+3,19713F-HRTimelineGroup
EFG International AGin group EFG International AG20,049$5.18M0.11%-3,52013F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC20,014$5.17M0.31%013F-HRTimelineGroup
Tetragon Partners GP Ltdin group Tetragon Partners GP Ltd19,668$5.08M1%+7,85413F-HRTimelineGroup
GW&K Investment Management, LLC19,245$4.97M0.04%-33613F-HRTimeline
Lisanti Capital Growth, LLC18,515$4.78M1.21%new13F-HRTimeline
ZACKS INVESTMENT MANAGEMENT17,919$4.63M0.04%new13F-HRTimeline
Campbell & CO Investment Adviser LLC17,795$4.6M0.26%new13F-HRTimeline
Rafferty Asset Management, LLC17,687$4.57M0.02%-6,58113F-HRTimeline
State of Alaska, Department of Revenue17,484$4.51M0.05%-41813F-HRTimeline
Thrivent Financial for Lutheransin group Thrivent Financial for Luther…17,226$4.45M0.01%-50813F-HRTimelineGroup
Rhenman & Partners Asset Management AB16,675$4.31M0.53%-8,32513F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding16,646$4.29M+2,283Timeline
Informed Momentum Co LLC16,483$4.26M0.49%-8,18413F-HRTimeline
Creative Planningin group Creative Planning15,937$4.12M<0.01%+2,05613F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…15,756$4.07M0.01%013F-HRTimeline
NEW YORK STATE TEACHERS RETIREMENT SYST…15,637$4.04M0.01%-1313F-HRTimeline
CIM, LLC14,990$3.87M0.56%new13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN14,988$3.87M<0.01%-16,58413F-HR/ATimelineGroup
TUDOR INVESTMENT CORP ET AL14,476$3.74M0.02%+13,10113F-HRTimeline
Illinois Municipal Retirement Fund14,151$3.66M0.05%+1,45213F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC14,114$3.65M<0.01%-4313F-HRTimelineGroup
Natixis Investment Managersgroup of 2 filers holding13,861$3.58M-741Timeline
MetLife Investment Management, LLCin group MetLife Investment Management…13,542$3.5M0.02%-30213F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC13,520$3.49M0.03%+3,76913F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding13,146$3.4M+7,175Timeline
CREDIT AGRICOLE S Ain group CREDIT AGRICOLE S A12,976$3.35M0.01%013F-HRTimelineGroup
Evolutionary Tree Capital Management, L…12,314$3.18M5.98%-4,49713F-HRTimeline
Bridge City Capital, LLC12,045$3.11M0.86%-9013F-HRTimeline
Torray Investment Partners LLC12,032$3.11M0.46%+4713F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC11,983$3.1M<0.01%+1,40613F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC11,591$2.99M<0.01%+1,70413F-HRTimeline
Louisiana State Employees Retirement Sy…11,400$2.94M0.05%-40013F-HRTimeline
Privium Fund Management B.V.11,170$2.89M0.6%-1,00013F-HRTimeline
Atika Capital Management LLCin group Atika Capital Management LLC10,625$2.74M0.43%new13F-HRTimelineGroup
State of Tennessee, Department of Treas…10,254$2.65M0.01%+6113F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…10,227$2.64M<0.01%-42413F-HRTimelineGroup
NOMURA ASSET MANAGEMENT CO LTDgroup of 2 filers holding10,218$2.64M+627Timeline
RENAISSANCE TECHNOLOGIES LLC9,600$2.48M<0.01%+6,30013F-HRTimeline
VIRGINIA RETIREMENT SYSTEMS ET Al9,500$2.45M0.02%+50013F-HRTimeline
BROWN CAPITAL MANAGEMENT LLC9,247$2.39M0.34%new13F-HRTimeline
PROFUND ADVISORS LLC8,790$2.27M0.08%-1,09713F-HRTimeline
CLOUGH CAPITAL PARTNERS L Pin group CLOUGH CAPITAL PARTNERS L P8,502$2.2M0.21%+69613F-HRTimelineGroup
Erste Asset Management GmbHin group Erste Asset Management GmbH8,700$2.15M0.02%+3,00013F-HRTimelineGroup
Aquatic Capital Management LLC8,257$2.13M0.06%new13F-HRTimeline
TEALWOOD ASSET MANAGEMENT INC7,664$1.98M0.9%-4913F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd7,479$1.93M0.03%new13F-HRTimelineGroup
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…7,433$1.92M0.01%+2413F-HRTimelineGroup
AMALGAMATED BANK7,379$1.91M0.01%-10713F-HRTimeline
Decheng Capital LLC7,300$1.89M0.29%-10,00013F-HRTimeline
MARTINGALE ASSET MANAGEMENT L P7,208$1.86M0.05%+2,70213F-HRTimeline
Quantum Private Wealth, LLC7,181$1.85M0.57%013F-HRTimeline
YOUSIF CAPITAL MANAGEMENT, LLC7,131$1.84M0.02%-3613F-HRTimeline
Legato Capital Management LLC6,973$1.8M0.16%+5,06013F-HRTimeline
FIFTH THIRD BANK, NATIONAL ASSOCIATIONgroup of 2 filers holding6,944$1.79M+6,798Timeline
Police & Firemen's Retirement System of…6,747$1.74M0.01%013F-HRTimeline
TEACHERS RETIREMENT SYSTEM OF THE STATE…6,458$1.67M0.01%013F-HRTimeline
STRS OHIO6,400$1.65M0.01%-10013F-HRTimeline
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCH…6,382$1.65M0.01%-713F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …6,229$1.61M<0.01%+1,14313F-HRTimelineGroup
Cetera Investment Advisers6,206$1.6M<0.01%+1,59013F-HRTimeline
Sanctuary Advisors, LLC6,030$1.56M0.01%new13F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM5,973$1.54M0.01%-6513F-HRTimeline
OREGON PUBLIC EMPLOYEES RETIREMENT FUND5,949$1.54M0.02%+5313F-HRTimeline
SG Americas Securities, LLC5,899$1.52M<0.01%-13,01013F-HRTimeline
FORA Capital, LLC5,732$1.48M0.11%+3,62013F-HRTimeline
Amundiin group Amundi5,706$1.47M<0.01%+1,95213F-HRTimelineGroup
China Universal Asset Management Co., L…5,187$1.34M0.1%+46213F-HRTimeline
ProShare Advisors LLC5,177$1.34M<0.01%-93913F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…5,139$1.33M<0.01%+1,27513F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC4,969$1.28M<0.01%-55,09313F-HRTimelineGroup
KENNEDY CAPITAL MANAGEMENT LLC4,904$1.27M0.03%+40313F-HRTimeline
Odyssean, LLC4,819$1.24M0.45%+1,80513F-HRTimeline
KLP KAPITALFORVALTNING AS4,800$1.24M<0.01%+10013F-HRTimeline
COOKSON PEIRCE & CO INC4,694$1.21M0.05%-1,26013F-HRTimeline
HEALTHCARE OF ONTARIO PENSION PLAN TRUS…4,664$1.2M<0.01%new13F-HRTimeline
ALLSTATE CORPin group ALLSTATE CORP4,433$1.15M0.01%new13F-HRTimelineGroup
Seven Fleet Capital Management LP4,316$1.11M0.35%+31613F-HR/ATimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC4,119$1.06M<0.01%-10,53913F-HRTimelineGroup
OMERS ADMINISTRATION Corp4,100$1.06M0.01%new13F-HRTimeline
Regal Investment Advisors LLC4,050$1.05M0.06%-31013F-HRTimeline
Maryland State Retirement & Pension Sys…3,764$972K0.02%-1013F-HRTimeline
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC3,518$909K0.01%-3,73413F-HRTimelineGroup
PIER 88 INVESTMENT PARTNERS LLC3,500$904K0.23%-47013F-HR/ATimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…3,449$891K0.25%+65713F-HRTimelineGroup
Ellsworth Advisors, LLC3,245$838K0.16%new13F-HRTimeline
Resona Asset Management Co.,Ltd.in group Resona Asset Management Co.,L…3,194$825K<0.01%+13713F-HRTimelineGroup
Quadrature Capital Ltdin group Quadrature Capital Ltd3,189$824K0.01%new13F-HRTimelineGroup
Quantinno Capital Management LP3,171$819K<0.01%+26713F-HRTimeline
Corient Private Wealth LPin group Corient Private Wealth LP3,523$818K<0.01%-34,82313F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/3,162$817K<0.01%+93113F-HRTimelineGroup
ASSETMARK, INCin group ASSETMARK, INC3,157$816K<0.01%new13F-HRTimelineGroup
DNB Asset Management ASin group DNB Asset Management AS3,100$801K<0.01%+713F-HRTimelineGroup
HANSEATIC MANAGEMENT SERVICES INC2,997$774K0.74%13F-HRTimeline
Confluence Wealth Services, Inc.2,922$755K0.03%013F-HRTimeline
Freestone Grove Partners LP2,922$755K0.01%new13F-HRTimeline
Cinctive Capital Management LP2,874$742K0.05%new13F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS2,823$729K<0.01%-39913F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC2,726$704K<0.01%-383,77913F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC2,717$702K<0.01%new13F-HRTimelineGroup
Pacer Advisors, Inc.2,547$658K<0.01%+83513F-HR/ATimeline
TRANSCEND CAPITAL ADVISORS, LLC2,511$649K0.05%+83113F-HRTimeline
Allspring Global Investments Holdings, …in group Allspring Global Investments …2,475$641K<0.01%+24113F-HRTimelineGroup
BLAIR WILLIAM & CO/IL2,448$632K<0.01%-72913F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…2,363$610K<0.01%013F-HRTimeline
XPONANCE LLC2,339$604K<0.01%+38013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…2,318$599K0.02%+63213F-HRTimelineGroup
Crossmark Global Holdings, Inc.2,294$593K0.01%+17013F-HRTimeline
E Fund Management Co., Ltd.2,281$589K0.02%13F-HRTimeline
Empowered Funds, LLC2,276$588K<0.01%new13F-HR/ATimeline
Blackstone Inc.in group Blackstone Inc.2,246$580K<0.01%new13F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
Pathstone Holdings, LLCin group Pathstone Holdings, LLC2,241$579K<0.01%-4013F-HRTimelineGroup
Entropy Technologies, LP2,200$568K0.03%-30313F-HRTimeline
Janney Montgomery Scott LLC2,170$561K<0.01%-22813F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC2,171$561K<0.01%013F-HRTimeline
Swiss Life Asset Management Ltdin group Swiss Life Asset Management L…2,165$559K<0.01%+1,17413F-HRTimelineGroup
Vontobel Holding Ltd.in group Vontobel Holding Ltd.2,118$547K<0.01%-3713F-HRTimelineGroup
Ballentine Partners, LLC2,115$546K0.01%+713F-HRTimeline
Ameritas Investment Partners, Inc.group of 2 filers holding2,056$531K+43Timeline
HighTower Advisors, LLC2,049$529K<0.01%+93713F-HRTimeline
Yorktown Management & Research Co Inc2,000$517K0.43%013F-HRTimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC2,000$517K<0.01%new13F-HRTimelineGroup