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Disclosery

KRYS KRYSTAL BIOTECH INC

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Stock (common), issuer CIK 1711279

262 managers (266 13F filers) reported a position in KRYS shares at 2024-12-31, 27,774,032 shares in all. 28 filers opened a position and 52 filers sold out during the quarter.

Managers
262
13F filers
266
New
28
Added
95
Reduced
97
Sold out
52
Shares held by filers
27,774,032

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2024

Filers in the available 13F reports with a share position at 2024-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC4,314,014$676M0.04%+21,13313F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.4,033,872$632M0.01%+40,74913F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding2,879,851$451M+28,569Timeline
Avoro Capital Advisors LLC2,628,822$412M5.83%+6,60013F-HRTimeline
STATE STREET CORPin group STATE STREET CORP1,278,975$200M0.01%-173,83613F-HRTimelineGroup
Capital World Investors879,203$138M0.02%+12013F-HRTimeline
Frazier Life Sciences Management, L.P.788,460$124M5.13%-200,00013F-HRTimeline
Redmile Group, LLCin group Redmile Group, LLC753,175$118M8.22%-57,07013F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC591,596$92.7M0.01%-3513F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP588,599$92.2M0.02%-11,66213F-HRTimelineGroup
Hood River Capital Management LLC512,726$80.3M1.19%+10,62213F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/509,459$79.8M0.01%+71,20013F-HRTimeline
Soleus Capital Management, L.P.358,379$56.1M4.25%+141,40013F-HRTimeline
UBS Group AGgroup of 2 filers holding310,333$48.6M+49,059Timeline
Nuveen Asset Management, LLCin group TIAA304,115$47.6M0.01%-7,74013F-HRTimelineGroup
JENNISON ASSOCIATES LLC303,521$47.5M0.03%-106,53613F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC277,175$43.4M0.01%-24,17913F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.275,195$43.1M0.01%-90,35613F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP262,263$41.1M0.01%+23,57213F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY256,275$40.1M<0.01%-19,52913F-HR/ATimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co243,170$38.1M0.01%+2,95413F-HRTimelineGroup
Woodline Partners LP221,102$34.6M0.23%+41,28713F-HRTimeline
NORGES BANK219,528$34.4M<0.01%-24,56913F-HRTimeline
LORD, ABBETT & CO. LLC215,628$33.8M0.11%-68,53113F-HRTimeline
BRAIDWELL LP200,500$31.4M0.93%+31,80913F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources184,027$28.8M0.01%-59,73313F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP169,934$26.6M0.28%013F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp169,346$26.5M<0.01%-2,30713F-HRTimelineGroup
TimesSquare Capital Management, LLC158,868$24.9M0.36%+44,64613F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO151,835$23.8M<0.01%+23,93413F-HRTimelineGroup
SEGALL BRYANT & HAMILL, LLC149,309$23.4M0.32%-7,83513F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCgroup of 2 filers holding123,460$19.3M+3,734Timeline
Driehaus Capital Management LLC121,702$19.1M0.16%-41,60213F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC113,476$17.8M<0.01%+23,72713F-HRTimelineGroup
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…112,089$17.6M0.02%-3,26113F-HRTimelineGroup
C WorldWide Group Holding A/Sin group C WorldWide Group Holding A/S105,809$16.6M0.2%-30,00013F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC102,061$16M0.01%13F-HR/ATimelineGroup
CITIGROUP INCin group CITIGROUP INC99,633$15.6M0.02%+64,54913F-HRTimelineGroup
EVENTIDE ASSET MANAGEMENT, LLC95,781$15M0.27%013F-HRTimeline
S SQUARED TECHNOLOGY, LLC95,215$14.9M6.2%+20,00013F-HRTimeline
Skandinaviska Enskilda Banken AB (publ)89,047$14.2M0.06%-37,03513F-HRTimeline
Handelsbanken Fonder AB85,300$13.4M0.05%-9,40013F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC81,328$12.7M0.01%-16,95713F-HRTimeline
Decheng Capital LLC76,772$12M2.58%+5,00013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/75,799$11.9M<0.01%-28,85513F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC74,701$11.7M0.01%+4,12313F-HR/ATimelineGroup
Legal & General Group Plcin group Legal & General Group Plc69,425$10.9M<0.01%+3,17013F-HRTimelineGroup
RHUMBLINE ADVISERS69,136$10.8M0.01%-1,17313F-HR/ATimeline
Public Sector Pension Investment Board63,010$9.87M0.04%+9,35413F-HRTimeline
Aberdeen Group plcin group Aberdeen Group plc57,033$8.93M0.02%+13,97913F-HRTimelineGroup
Integral Health Asset Management, LLC55,000$8.62M0.76%new13F-HRTimeline
Janney Montgomery Scott LLC52,592$8.24M0.02%+15,54513F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC52,429$8.21M<0.01%-4,11113F-HR/ATimelineGroup
OBERWEIS ASSET MANAGEMENT INC/46,800$7.33M0.35%013F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC41,193$6.82M0.01%+3,25413F-HRTimelineGroup
TD Asset Management Inc43,480$6.81M0.01%+10,00013F-HRTimeline
Corient Private Wealth LPin group Corient Private Wealth LP43,009$6.74M0.01%-4,67813F-HRTimelineGroup
Swiss National Bank42,400$6.64M<0.01%+3,30013F-HRTimeline
Palisades Investment Partners, LLC40,479$6.34M2.68%+3,43613F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…38,468$6.03M0.01%+28,91413F-HRTimelineGroup
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…36,518$5.72M0.06%-4813F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC35,855$5.62M0.01%+17,67413F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …35,206$5.52M<0.01%+3,98113F-HRTimelineGroup
GW&K Investment Management, LLC34,930$5.47M0.05%-1,09913F-HRTimeline
ALLIANCEBERNSTEIN L.P.31,120$4.88M<0.01%+1,40013F-HRTimeline
Allspring Global Investments Holdings, …in group Allspring Global Investments …29,777$4.66M0.01%-81,92813F-HRTimelineGroup
KENNEDY CAPITAL MANAGEMENT LLC27,711$4.34M0.1%+22,51713F-HRTimeline
Rafferty Asset Management, LLC27,201$4.26M0.02%-18,63913F-HRTimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co26,754$4.19M0.01%-2213F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\25,361$3.97M<0.01%+9,75013F-HR/ATimelineGroup
Verition Fund Management LLC24,902$3.9M0.02%+8,90213F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD24,502$3.84M0.01%+1,43413F-HRTimeline
Edgestream Partners, L.P.23,810$3.73M0.16%-8,44713F-HRTimeline
Rhenman & Partners Asset Management AB23,750$3.72M0.38%+6,75013F-HRTimeline
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC23,500$3.68M0.08%013F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND23,382$3.66M<0.01%-2,48113F-HR/ATimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …23,197$3.63M0.01%13F-HRTimelineGroup
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP23,169$3.63M<0.01%-16,24213F-HRTimelineGroup
Caption Management, LLC22,339$3.5M0.14%new13F-HRTimeline
HRT FINANCIAL LP22,007$3.45M0.02%new13F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO21,164$3.32M<0.01%-13,08513F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…20,388$3.19M<0.01%+1,12713F-HR/ATimeline
Thrivent Financial for Lutheransin group Thrivent Financial for Luther…19,563$3.06M0.01%-29113F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC18,956$2.97M<0.01%-28,66713F-HRTimelineGroup
Erste Asset Management GmbHin group Erste Asset Management GmbH18,200$2.9M0.04%013F-HRTimelineGroup
EFG Asset Management (North America) Co…17,714$2.78M0.38%+4,18513F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN16,928$2.65M<0.01%+2,97213F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding16,163$2.54M-262Timeline
NEW YORK STATE TEACHERS RETIREMENT SYST…15,879$2.49M0.01%013F-HRTimeline
Fiera Capital Corpin group Fiera Capital Corp15,673$2.46M0.01%-52713F-HRTimelineGroup
DekaBank Deutsche Girozentrale15,503$2.44M<0.01%013F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…14,997$2.35M0.01%+68013F-HRTimelineGroup
State of Alaska, Department of Revenue14,423$2.26M0.03%-513F-HRTimeline
Illinois Municipal Retirement Fund14,146$2.22M0.03%+1,50513F-HRTimeline
Hennion & Walsh Asset Management, Inc.13,678$2.14M0.1%-23213F-HRTimeline
Corebridge Financial, Inc.in group Corebridge Financial, Inc.13,225$2.07M0.01%-1,03213F-HRTimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.13,048$2.04M<0.01%+22913F-HRTimelineGroup
SCHRODER INVESTMENT MANAGEMENT GROUP12,607$2.01M<0.01%013F-HRTimeline
Louisiana State Employees Retirement Sy…12,200$1.91M0.04%013F-HRTimeline
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…11,803$1.85M0.01%+1,91013F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…11,704$1.83M<0.01%-97613F-HRTimelineGroup
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC11,630$1.82M<0.01%+12113F-HRTimelineGroup
Redwood Investments, LLC11,343$1.78M0.48%-5313F-HRTimeline
State of Tennessee, Department of Treas…11,299$1.77M0.01%-26313F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC11,015$1.73M<0.01%+10,91913F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC10,900$1.71M<0.01%-3,50013F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC10,839$1.7M0.02%+3,56913F-HRTimeline
Evolutionary Tree Capital Management, L…10,700$1.68M1.71%+1,58813F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP10,331$1.62M<0.01%new13F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson10,071$1.58M<0.01%+1,40013F-HRTimelineGroup
LOS ANGELES CAPITAL MANAGEMENT LLC9,884$1.55M0.01%013F-HRTimeline
YOUSIF CAPITAL MANAGEMENT, LLC9,777$1.53M0.02%-17213F-HRTimeline
ExodusPoint Capital Management, LP9,761$1.53M0.02%new13F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC9,559$1.5M<0.01%-6,14713F-HRTimelineGroup
Atle Fund Management AB9,202$1.47M0.7%013F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC9,339$1.46M<0.01%+98913F-HRTimelineGroup
Privium Fund Management B.V.9,250$1.45M0.33%+2,90013F-HRTimeline
ZACKS INVESTMENT MANAGEMENT9,078$1.42M0.01%-36913F-HRTimeline
TEACHERS RETIREMENT SYSTEM OF THE STATE…9,010$1.41M0.01%013F-HRTimeline
COMERICA BANK8,890$1.39M0.01%-20713F-HR/ATimeline
ProShare Advisors LLC8,848$1.39M<0.01%+1,96713F-HRTimeline
Maryland State Retirement & Pension Sys…8,523$1.34M0.03%-1513F-HRTimeline
CWM, LLCin group CWM, LLC8,053$1.26M0.01%-5,79313F-HRTimelineGroup
Jackson Creek Investment Advisors LLC8,052$1.26M0.38%-24413F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS7,789$1.22M<0.01%-2,64413F-HRTimelineGroup
Perigon Wealth Management, LLC8,289$1.2M0.03%+12313F-HRTimeline
Schonfeld Strategic Advisors LLC7,604$1.19M0.01%+1,15313F-HRTimeline
BLAIR WILLIAM & CO/IL7,443$1.17M<0.01%+1,87513F-HRTimeline
AMALGAMATED BANK7,436$1.17M0.01%+213F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.7,427$1.16M<0.01%-1,91913F-HRTimelineGroup
STRS OHIO7,300$1.14M<0.01%+2,30013F-HRTimeline
Quantum Private Wealth, LLC7,205$1.13M0.36%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…6,999$1.1M0.02%+6,91213F-HRTimelineGroup
Aquatic Capital Management LLC6,901$1.08M0.03%new13F-HRTimeline
Ensign Peak Advisors, Inc6,569$1.03M<0.01%013F-HRTimeline
WINTON GROUP Ltdin group WINTON GROUP Ltd6,565$1.03M0.07%+1,27413F-HRTimelineGroup
TEACHER RETIREMENT SYSTEM OF TEXAS6,383$1M<0.01%+1,36913F-HRTimeline
PROFUND ADVISORS LLC6,321$990K0.04%-3,66413F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM6,242$978K0.01%+48713F-HRTimeline
China Universal Asset Management Co., L…6,098$955K0.09%+57213F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…6,054$948K<0.01%+1,44013F-HRTimeline
OREGON PUBLIC EMPLOYEES RETIREMENT FUND5,975$936K0.02%-513F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…5,807$910K<0.01%-6013F-HRTimeline
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCH…5,403$846K0.01%-113F-HRTimeline
Creative Planningin group Creative Planning5,397$845K<0.01%-34713F-HRTimelineGroup
Police & Firemen's Retirement System of…5,283$828K0.01%13F-HRTimeline
MARTINGALE ASSET MANAGEMENT L P5,136$805K0.02%+113F-HRTimeline
Nicholas Investment Partners, LP5,086$797K0.07%-13,72113F-HRTimeline
Bellevue Group AGin group Bellevue Group AG5,047$791K0.02%+26813F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC4,866$762K<0.01%+19013F-HRTimeline
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC4,862$762K0.01%+92713F-HRTimelineGroup
Jain Global LLC4,800$752K0.02%13F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC4,519$718K<0.01%+2,98813F-HRTimelineGroup
KLP KAPITALFORVALTNING AS4,300$674K<0.01%13F-HRTimeline
CenterBook Partners LP4,283$671K0.04%new13F-HRTimeline
Pathstone Holdings, LLCin group Pathstone Holdings, LLC4,252$666K<0.01%-79513F-HRTimelineGroup
HighVista Strategies LLC4,217$661K0.25%new13F-HRTimeline
HUSSMAN STRATEGIC ADVISORS, INC.4,200$658K0.19%new13F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE4,102$643K<0.01%+1,50013F-HRTimelineGroup
PIER 88 INVESTMENT PARTNERS LLC3,750$587K0.12%+22013F-HRTimeline
Cynosure Group, LLC3,630$569K0.08%-35913F-HRTimeline
Main Management ETF Advisors, LLCin group Main Management ETF Advisors,…3,560$558K0.03%-32013F-HRTimelineGroup
Entropy Technologies, LP3,500$548K0.06%new13F-HRTimeline
GSA CAPITAL PARTNERS LLP3,464$543K0.04%new13F-HRTimeline
Summit Global Investmentsin group Summit Global Investments3,453$541K0.03%new13F-HRTimelineGroup
Mariner, LLCin group Mariner, LLC3,375$529K<0.01%-24713F-HRTimelineGroup
CREDIT AGRICOLE S Ain group CREDIT AGRICOLE S A3,336$523K<0.01%013F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/3,325$521K<0.01%+17913F-HRTimelineGroup
Parallel Advisors, LLC3,237$507K0.01%013F-HRTimeline
AlphaQuest LLC3,020$473K0.06%+1,62213F-HRTimeline
Vontobel Holding Ltd.in group Vontobel Holding Ltd.2,984$467K<0.01%-4,53513F-HRTimelineGroup
LPL Financial LLC2,946$462K<0.01%+1,79913F-HRTimeline
Confluence Wealth Services, Inc.2,920$453K0.03%013F-HRTimeline
Nebula Research & Development LLC2,670$418K0.05%-2,03513F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…2,595$407K0.01%+8213F-HRTimelineGroup
Vident Advisory, LLCin group Vident Advisory, LLC2,492$390K0.01%-8313F-HRTimelineGroup
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…2,363$370K<0.01%013F-HRTimeline
SHERBROOKE PARK ADVISERS LLC2,353$369K0.12%-2613F-HRTimeline
CIBC WORLD MARKETS CORP2,321$364K<0.01%new13F-HRTimeline
Crossmark Global Holdings, Inc.2,307$362K0.01%+12113F-HRTimeline
Cetera Investment Advisers2,176$341K<0.01%+3113F-HRTimeline
FOX RUN MANAGEMENT, L.L.C.2,161$339K0.06%new13F-HRTimeline
Ballentine Partners, LLC2,145$336K0.01%+5613F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd2,102$329K0.03%new13F-HRTimelineGroup
Graham Capital Management, L.P.2,082$326K0.01%-14913F-HRTimeline
VIRTUS ADVISERS, LLCin group Virtus Investment Advisers, L…2,016$316K0.13%+21413F-HRTimelineGroup
FARALLON CAPITAL MANAGEMENT, L.L.C.2,000$313K<0.01%013F-HRTimeline
E Fund Management Co., Ltd.1,934$303K0.02%-1,00713F-HRTimeline
Argent Trust Co1,899$297K0.01%013F-HRTimeline
OLD MISSION CAPITAL LLC1,868$293K0.01%new13F-HRTimeline
XPONANCE LLC1,785$280K<0.01%+15513F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…1,680$263K<0.01%+3613F-HRTimelineGroup
Headlands Technologies LLC1,635$256K0.03%-5,19913F-HRTimeline
DNB Asset Management ASin group DNB Asset Management AS1,537$241K<0.01%-75913F-HRTimelineGroup
MACKENZIE FINANCIAL CORP1,532$240K<0.01%+4613F-HR/ATimeline
AlphaCentric Advisors LLC1,474$231K0.23%new13F-HRTimeline
Sound View Wealth Advisors Group, LLC1,420$222K0.02%+22013F-HRTimeline
Pacer Advisors, Inc.1,400$219K<0.01%new13F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…1,396$219K0.01%-69813F-HRTimelineGroup
TRANSCEND CAPITAL ADVISORS, LLC1,382$217K0.02%013F-HRTimeline