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Disclosery

KRYS KRYSTAL BIOTECH INC

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Stock (common), issuer CIK 1711279

296 managers (301 13F filers) reported a position in KRYS shares at 2025-03-31, 27,607,453 shares in all. 62 filers opened a position and 27 filers sold out during the quarter.

Managers
296
13F filers
301
New
62
Added
88
Reduced
112
Sold out
27
Shares held by filers
27,607,453

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2025

Filers in the available 13F reports with a share position at 2025-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC4,320,832$779M0.05%+6,81813F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.3,943,165$711M0.02%-90,70713F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding2,827,228$510M-52,623Timeline
Avoro Capital Advisors LLC2,731,000$492M7.69%+102,17813F-HRTimeline
STATE STREET CORPin group STATE STREET CORP1,226,707$221M0.01%-52,26813F-HRTimelineGroup
Capital World Investors954,468$172M0.03%+75,26513F-HRTimeline
Redmile Group, LLCin group Redmile Group, LLC737,675$133M12.57%-15,50013F-HRTimelineGroup
Frazier Life Sciences Management, L.P.688,460$124M5.67%-100,00013F-HRTimeline
UBS Group AGgroup of 2 filers holding656,625$118M+346,292Timeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC612,353$110M0.01%+20,75713F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP533,919$96.3M0.02%-54,68013F-HRTimelineGroup
Hood River Capital Management LLC524,644$94.6M1.61%+11,91813F-HRTimeline
Soleus Capital Management, L.P.441,758$79.6M6.25%+83,37913F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/410,861$74.1M0.01%-98,59813F-HRTimeline
BRAIDWELL LP400,744$72.3M2.54%+200,24413F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY298,205$53.8M<0.01%+41,93013F-HRTimelineGroup
NORGES BANK273,209$49.3M0.01%+53,68113F-HR/ATimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP259,995$46.9M0.01%-2,26813F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.254,486$45.9M0.01%-20,70913F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co250,514$45.2M0.01%+7,34413F-HR/ATimelineGroup
Nuveen, LLCin group TIAA234,180$42.2M0.01%13F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC233,640$42.1M0.01%-43,53513F-HR/ATimelineGroup
Woodline Partners LP222,043$40M0.26%+94113F-HRTimeline
T. Rowe Price Investment Management, In…185,550$33.5M0.02%new13F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp169,179$30.5M0.01%-16713F-HRTimelineGroup
LORD, ABBETT & CO. LLC151,225$27.3M0.1%-64,40313F-HRTimeline
SEGALL BRYANT & HAMILL, LLC145,337$26.2M0.4%-3,97213F-HRTimeline
TimesSquare Capital Management, LLC142,183$25.6M0.41%-16,68513F-HRTimeline
1832 Asset Management L.P.136,000$24.5M0.05%new13F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCgroup of 2 filers holding126,344$22.8M+2,884Timeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO100,774$18.2M<0.01%-51,06113F-HRTimelineGroup
S SQUARED TECHNOLOGY, LLC97,215$17.5M8.97%+2,00013F-HRTimeline
EVENTIDE ASSET MANAGEMENT, LLC95,781$17.3M0.34%013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/92,561$16.7M<0.01%+16,76213F-HRTimelineGroup
C WorldWide Group Holding A/Sin group C WorldWide Group Holding A/S85,809$15.5M0.19%-20,00013F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC81,999$14.8M0.04%+72,44013F-HR/ATimelineGroup
Public Sector Pension Investment Board80,264$14.5M0.06%+17,25413F-HRTimeline
Handelsbanken Fonder AB74,300$13.4M0.06%-11,00013F-HRTimeline
CITIGROUP INCin group CITIGROUP INC73,525$13.3M0.01%-26,10813F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC72,815$13.1M0.01%-8,51313F-HRTimeline
RHUMBLINE ADVISERS68,727$12.4M0.01%-40913F-HR/ATimeline
Legal & General Group Plcin group Legal & General Group Plc66,509$12M<0.01%-2,91613F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC65,961$11.9M<0.01%-36,10013F-HRTimelineGroup
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…65,262$11.8M0.01%-46,82713F-HRTimelineGroup
Decheng Capital LLC65,000$11.7M3.29%-11,77213F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC64,601$11.6M0.01%-10,10013F-HR/ATimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC60,508$10.9M<0.01%-52,96813F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC60,388$10.9M0.01%+41,43213F-HRTimelineGroup
Integral Health Asset Management, LLC60,000$10.8M1.2%+5,00013F-HRTimeline
Skandinaviska Enskilda Banken AB (publ)59,978$10.8M0.05%-29,06913F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.49,892$9M0.01%+42,46513F-HRTimelineGroup
OBERWEIS ASSET MANAGEMENT INC/46,800$8.44M0.42%013F-HRTimeline
Janney Montgomery Scott LLC45,935$8.28M0.02%-6,65713F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC44,997$8.11M<0.01%-7,43213F-HR/ATimelineGroup
Corient Private Wealth LPin group Corient Private Wealth LP42,127$7.6M0.01%-88213F-HRTimelineGroup
Swiss National Bank41,800$7.54M0.01%-60013F-HRTimeline
KENNEDY CAPITAL MANAGEMENT LLC41,518$7.49M0.18%+13,80713F-HRTimeline
Palisades Investment Partners, LLC40,696$7.34M3.68%+21713F-HRTimeline
TD Asset Management Inc40,268$7.26M0.01%-3,21213F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…37,781$6.81M0.01%+37,33613F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc37,301$6.73M0.01%-19,73213F-HRTimelineGroup
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…36,431$6.57M0.08%-8713F-HR/ATimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding36,071$6.5M-2,397Timeline
GW&K Investment Management, LLC34,100$6.15M0.06%-83013F-HRTimeline
JENNISON ASSOCIATES LLC33,594$6.06M<0.01%-269,92713F-HRTimeline
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP33,125$5.97M0.01%+9,95613F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …32,366$5.84M0.01%-2,84013F-HRTimelineGroup
Beacon Harbor Wealth Advisors, Inc.32,235$5.81M1.35%new13F-HRTimeline
ALLIANCEBERNSTEIN L.P.31,120$5.61M<0.01%013F-HRTimeline
Lisanti Capital Growth, LLC30,410$5.48M1.63%new13F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC27,311$4.92M0.01%-13,88213F-HRTimelineGroup
CASTLEARK MANAGEMENT LLC26,120$4.71M0.16%new13F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC24,929$4.49M0.02%+15,04513F-HRTimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co24,609$4.43M0.01%-2,14513F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD24,183$4.36M0.01%-31913F-HRTimeline
Rafferty Asset Management, LLC24,161$4.36M0.02%-3,04013F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC23,663$4.27M0.01%-12,19213F-HR/ATimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC23,500$4.24M0.1%013F-HRTimelineGroup
Atle Fund Management AB23,491$4.24M1.87%+14,28913F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND23,382$4.22M0.01%013F-HR/ATimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\21,737$3.92M<0.01%-3,62413F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…20,126$3.63M<0.01%-26213F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources19,013$3.43M<0.01%-165,01413F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO18,691$3.37M<0.01%-2,47313F-HR/ATimelineGroup
Verition Fund Management LLC18,625$3.36M0.02%-6,27713F-HRTimeline
Schonfeld Strategic Advisors LLC18,624$3.36M0.02%+11,02013F-HRTimeline
Thrivent Financial for Lutheransin group Thrivent Financial for Luther…18,590$3.35M0.01%-97313F-HR/ATimelineGroup
Erste Asset Management GmbHin group Erste Asset Management GmbH18,200$3.35M0.04%013F-HRTimelineGroup
Rhenman & Partners Asset Management AB17,750$3.2M0.37%-6,00013F-HRTimeline
EFG Asset Management (North America) Co…17,371$3.13M0.52%-34313F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP17,224$3.11M<0.01%+6,89313F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN17,135$3.09M<0.01%+20713F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding16,857$3.05M+694Timeline
Fieldview Capital Management, LLC16,342$2.95M0.42%new13F-HRTimeline
NEW YORK STATE TEACHERS RETIREMENT SYST…15,979$2.88M0.01%+10013F-HRTimeline
DekaBank Deutsche Girozentrale15,503$2.82M0.01%013F-HRTimeline
Fiera Capital Corpin group Fiera Capital Corp15,645$2.82M0.01%-2813F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…14,524$2.62M0.01%-47313F-HRTimelineGroup
State of Alaska, Department of Revenue14,024$2.53M0.03%-39913F-HRTimeline
Evolutionary Tree Capital Management, L…13,343$2.41M2.8%+2,64313F-HRTimeline
SCHRODER INVESTMENT MANAGEMENT GROUP13,048$2.4M<0.01%+44113F-HRTimeline
Trexquant Investment LP13,122$2.37M0.03%new13F-HRTimeline
Corebridge Financial, Inc.in group Corebridge Financial, Inc.12,970$2.34M0.01%-25513F-HRTimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.12,781$2.3M<0.01%-26713F-HRTimelineGroup
Illinois Municipal Retirement Fund12,762$2.3M0.03%-1,38413F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …12,753$2.3M<0.01%-10,44413F-HRTimelineGroup
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC12,399$2.24M<0.01%+76913F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC12,131$2.19M<0.01%+2,79213F-HRTimelineGroup
Creative Planningin group Creative Planning12,086$2.18M<0.01%+6,68913F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC12,078$2.18M0.02%+1,23913F-HRTimeline
Louisiana State Employees Retirement Sy…11,900$2.15M0.04%-30013F-HRTimeline
Redwood Investments, LLC11,267$2.03M0.76%-7613F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC11,200$2.02M<0.01%+30013F-HRTimeline
State of Tennessee, Department of Treas…11,162$2.01M0.01%-13713F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…10,599$1.91M<0.01%-1,10513F-HRTimelineGroup
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…10,351$1.87M0.01%-1,45213F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson10,071$1.85M<0.01%013F-HRTimelineGroup
Hennion & Walsh Asset Management, Inc.10,205$1.84M0.08%-3,47313F-HRTimeline
ExodusPoint Capital Management, LP9,952$1.79M0.02%+19113F-HRTimeline
YOUSIF CAPITAL MANAGEMENT, LLC9,570$1.73M0.02%-20713F-HRTimeline
DARK FOREST CAPITAL MANAGEMENT LP9,437$1.7M0.08%new13F-HRTimeline
BLAIR WILLIAM & CO/IL9,433$1.7M0.01%+1,99013F-HRTimeline
TEACHERS RETIREMENT SYSTEM OF THE STATE…9,010$1.62M0.01%013F-HRTimeline
COMERICA BANK8,701$1.57M0.01%-18913F-HRTimeline
Perigon Wealth Management, LLC8,491$1.53M0.04%+20213F-HRTimeline
Pathstone Holdings, LLCin group Pathstone Holdings, LLC8,109$1.46M0.01%+3,85713F-HRTimelineGroup
Jackson Creek Investment Advisors LLC8,048$1.45M0.46%-413F-HRTimeline
VIRGINIA RETIREMENT SYSTEMS ET Al7,800$1.41M0.01%13F-HRTimeline
Privium Fund Management B.V.7,510$1.35M0.35%-1,74013F-HRTimeline
Maryland State Retirement & Pension Sys…7,351$1.33M0.03%-1,17213F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC7,303$1.32M<0.01%+2,43713F-HRTimeline
WINTON GROUP Ltdin group WINTON GROUP Ltd7,274$1.31M0.08%+70913F-HRTimelineGroup
Quantum Private Wealth, LLC7,205$1.3M0.49%013F-HRTimeline
AMALGAMATED BANK7,200$1.3M0.01%-23613F-HRTimeline
ProShare Advisors LLC7,151$1.29M<0.01%-1,69713F-HRTimeline
STRS OHIO6,900$1.24M0.01%-40013F-HRTimeline
Ensign Peak Advisors, Inc6,569$1.18M<0.01%013F-HRTimeline
Nebula Research & Development LLC6,220$1.12M0.1%+3,55013F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM6,171$1.11M0.01%-7113F-HRTimeline
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCH…6,057$1.09M0.01%+65413F-HRTimeline
PROFUND ADVISORS LLC5,963$1.08M0.05%-35813F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…5,807$1.05M<0.01%013F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS5,805$1.05M<0.01%-57813F-HRTimeline
OREGON PUBLIC EMPLOYEES RETIREMENT FUND5,802$1.05M0.02%-17313F-HRTimeline
China Universal Asset Management Co., L…5,778$1.04M0.1%-32013F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…5,742$1.04M<0.01%-31213F-HRTimeline
CIBC WORLD MARKETS CORP5,504$992K0.01%+3,18313F-HRTimeline
Police & Firemen's Retirement System of…5,420$977K0.01%+13713F-HRTimeline
Legato Capital Management LLC5,190$936K0.13%new13F-HRTimeline
MARTINGALE ASSET MANAGEMENT L P5,136$926K0.02%013F-HRTimeline
Main Management ETF Advisors, LLCin group Main Management ETF Advisors,…5,047$910K0.04%+1,48713F-HRTimelineGroup
Allspring Global Investments Holdings, …in group Allspring Global Investments …5,180$904K<0.01%-24,59713F-HRTimelineGroup
Gotham Asset Management, LLC4,804$866K0.01%new13F-HRTimeline
Summit Global Investmentsin group Summit Global Investments4,711$849K0.06%+1,25813F-HRTimelineGroup
HRT FINANCIAL LP4,680$843K0.01%-17,32713F-HRTimeline
Prime Capital Investment Advisors, LLC4,504$812K0.01%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS4,437$800K<0.01%-3,35213F-HRTimelineGroup
PIER 88 INVESTMENT PARTNERS LLC4,430$799K0.15%+68013F-HRTimeline
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/4,418$797K<0.01%+1,09313F-HRTimelineGroup
Eschler Asset Management LLPin group Eschler Asset Management LLP4,403$794K1.97%new13F-HRTimelineGroup
Bryce Point Capital, LLC4,286$790K0.59%new13F-HRTimeline
Regal Investment Advisors LLC4,307$777K0.06%new13F-HRTimeline
KLP KAPITALFORVALTNING AS4,300$775K<0.01%013F-HRTimeline
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.4,200$757K0.01%new13F-HRTimelineGroup
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC4,153$749K0.01%-70913F-HRTimelineGroup
Cynosure Group, LLC3,902$704K0.1%+27213F-HRTimeline
QUADRANT CAPITAL GROUP LLC3,883$700K0.03%+3,72613F-HRTimeline
FRED ALGER MANAGEMENT, LLCin group FRED ALGER MANAGEMENT, LLC3,728$672K<0.01%new13F-HRTimelineGroup
Allianz Asset Management GmbHin group Allianz SE3,715$670K<0.01%-38713F-HRTimelineGroup
M&T Bank Corpin group M&T Bank Corp3,700$667K<0.01%new13F-HRTimelineGroup
Mariner, LLCin group Mariner, LLC3,637$656K<0.01%+26213F-HRTimelineGroup
ROMAN BUTLER FULLERTON & CO3,867$654K0.25%new13F-HRTimeline
Advantage Alpha Capital Partners LP3,569$643K0.16%new13F-HRTimeline
Jain Global LLC3,442$621K0.01%-1,35813F-HRTimeline
AVIVA PLCin group AVIVA PLC3,256$587K<0.01%new13F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC2,983$538K0.01%new13F-HR/ATimelineGroup
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC2,875$508K<0.01%-1,64413F-HRTimelineGroup
Vident Advisory, LLCin group Vident Advisory, LLC2,787$502K0.01%+29513F-HRTimelineGroup
Aster Capital Management (DIFC) Ltd2,776$498K0.09%new13F-HRTimeline
Scientech Research LLC2,737$493K0.13%new13F-HRTimeline
Vontobel Holding Ltd.in group Vontobel Holding Ltd.2,700$487K<0.01%-28413F-HRTimelineGroup
Confluence Wealth Services, Inc.2,920$484K0.03%013F-HRTimeline
Bellevue Group AGin group Bellevue Group AG2,650$478K0.01%-2,39713F-HRTimelineGroup
EP Wealth Advisors, LLC2,621$473K<0.01%new13F-HRTimeline
CERTUITY, LLC2,585$466K0.05%+1,22013F-HRTimeline
Connor, Clark & Lunn Investment Managem…2,582$466K<0.01%new13F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…2,509$452K0.02%-8613F-HRTimelineGroup
Crossmark Global Holdings, Inc.2,370$427K0.01%+6313F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…2,363$426K<0.01%013F-HRTimeline
FOX RUN MANAGEMENT, L.L.C.2,354$424K0.07%+19313F-HRTimeline
Entropy Technologies, LP2,300$415K0.04%-1,20013F-HRTimeline
E Fund Management Co., Ltd.2,258$407K0.02%+32413F-HRTimeline
Graham Capital Management, L.P.2,179$393K0.01%+9713F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…2,141$386K<0.01%+46113F-HRTimelineGroup
Ballentine Partners, LLC2,136$385K0.01%-913F-HRTimeline
Cetera Investment Advisers2,089$377K<0.01%-8713F-HRTimeline
Virtus Investment Advisers, LLCgroup of 2 filers holding2,068$373K+52Timeline
OmniStar Financial Group, Inc.2,026$365K0.29%new13F-HRTimeline
FARALLON CAPITAL MANAGEMENT, L.L.C.2,000$361K<0.01%013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
ALPS ADVISORS INCin group ALPS ADVISORS INC1,920$346K<0.01%new13F-HRTimelineGroup