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Opaleye Management Inc.

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13F filer, CIK 1595855, BOSTON, MA

Opaleye Management Inc. reported $757,893,709 across 54 holdings for the quarter ended 2025-12-31, in a 13F-HR/A filed 2026-04-13. Its ten largest share positions make up 65.47% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR/A 0001493152-26-016299

Period
2025-12-31
Reported value
$758M
Holdings
54
Top 10 weight
65.47%
New
21
Sold out
10

Stakes and trades reported after 2025-12-31

13D, 13G and Form 4 filings by this filer's group, dated after the 13F period, on securities the quarter does not hold as shares.

Largest buys vs the previous quarter

SecurityShares changeApprox. value
CBIOnew+1,178,300$14M
ACOGadded+1,955,642$12.7M
RZLTadded+5,383,714$12.7M
SLGLadded+248,904$10.5M
KPTInew+930,000$6.84M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
IMNMexited-3,185,000-$37.3M
RYTMreduced-131,700-$14.1M
SRPTexited-585,000-$11.3M
LRMRexited-3,720,867-$10.6M
CDXSreduced-6,005,262-$9.79M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q4 2025

Share positions as resolved from 13F-HR/A 0001493152-26-016299, largest first. % of portfolio is the value over $757,893,709, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
HROWHARROW INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,990,000 shares; 2024Q4: 3,990,000 shares; 2025Q1: 3,955,000 shares; 2025Q2: 3,905,000 shares; 2025Q3: 3,905,000 shares; 2025Q4: 3,905,000 shares 3,905,000$191M25.25%0Timeline
LQDALIQUIDIA CORPORATIONQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,698,142 shares; 2024Q4: 1,698,142 shares; 2025Q1: 2,260,000 shares; 2025Q2: 2,475,000 shares; 2025Q3: 2,615,000 shares; 2025Q4: 2,435,000 shares 2,435,000$85M11.21%-180,000Timeline
ETONETON PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,780,000 shares; 2024Q4: 2,852,070 shares; 2025Q1: 2,852,070 shares; 2025Q2: 2,860,000 shares; 2025Q3: 2,860,000 shares; 2025Q4: 2,860,000 shares 2,860,000$48.4M6.38%0Timeline
RYTMRHYTHM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 500,000 shares; 2024Q4: 500,000 shares; 2025Q1: 490,000 shares; 2025Q2: 475,000 shares; 2025Q3: 461,700 shares; 2025Q4: 330,000 shares 330,000$35.3M4.66%-131,700Timeline
APGEAPOGEE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 363,257 shares; 2025Q4: 388,257 shares 388,257$29.3M3.87%+25,000Timeline
SNWVSANUWAVE HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 972,002 shares; 2025Q2: 980,000 shares; 2025Q3: 980,000 shares; 2025Q4: 981,267 shares 981,267$29.3M3.86%+1,267Timeline
STOKSTOKE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 25,000 shares; 2025Q1: 300,000 shares; 2025Q2: 562,120 shares; 2025Q3: 682,017 shares; 2025Q4: 695,000 shares 695,000$22.1M2.91%+12,983Timeline
OCULOCULAR THERAPEUTIX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 5,025,000 shares; 2024Q4: 4,342,500 shares; 2025Q1: 1,595,000 shares; 2025Q2: 1,595,000 shares; 2025Q3: 1,595,000 shares; 2025Q4: 1,595,000 shares 1,595,000$19.4M2.55%0Timeline
SLGLSOL-GEL TECHNOLOGIES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 204,835 shares; 2025Q4: 453,739 shares 453,739$19.1M2.52%+248,904Timeline
CGONCG ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 163,988 shares; 2025Q2: 266,000 shares; 2025Q3: 410,000 shares; 2025Q4: 410,000 shares 410,000$17M2.25%0Timeline
TGTXTG THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,280,000 shares; 2024Q4: 2,260,000 shares; 2025Q1: 535,000 shares; 2025Q2: 535,000 shares; 2025Q3: 535,000 shares; 2025Q4: 535,000 shares 535,000$15.9M2.1%0Timeline
IRONDISC MEDICINE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 85,000 shares; 2025Q2: 186,418 shares; 2025Q3: 193,773 shares; 2025Q4: 200,000 shares 200,000$15.9M2.1%+6,227Timeline
RZLTREZOLUTE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 466,563 shares; 2024Q4: 465,000 shares; 2025Q1: 465,000 shares; 2025Q2: 903,442 shares; 2025Q3: 903,442 shares; 2025Q4: 6,287,156 shares 6,287,156$14.8M1.96%+5,383,714Timeline
CBIOCRESCENT BIOPHARMA INC.Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,178,300 shares 1,178,300$14M1.84%newTimeline
ALKSALKERMES PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 450,000 shares; 2025Q4: 490,000 shares 490,000$13.7M1.81%+40,000Timeline
ACOGALPHA COGNITION INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 115,142 shares; 2025Q4: 2,070,784 shares 2,070,784$13.5M1.78%+1,955,642Timeline
ANNXANNEXON INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 2,600,000 shares; 2025Q4: 2,600,000 shares 2,600,000$13.1M1.72%0Timeline
EWTXEDGEWISE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 522,500 shares; 2024Q4: 480,000 shares; 2025Q1: 395,000 shares; 2025Q2: 490,000 shares; 2025Q3: 500,000 shares; 2025Q4: 500,000 shares 500,000$12.4M1.64%0Timeline
CDXSCODEXIS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 8,770,000 shares; 2024Q4: 8,840,000 shares; 2025Q1: 9,500,000 shares; 2025Q2: 12,600,000 shares; 2025Q3: 12,795,000 shares; 2025Q4: 6,789,738 shares 6,789,738$11.1M1.46%-6,005,262Timeline
PTGXPROTAGONIST THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 105,000 shares; 2024Q4: 105,000 shares; 2025Q1: 105,000 shares; 2025Q2: 105,000 shares; 2025Q3: 105,000 shares; 2025Q4: 105,000 shares 105,000$9.17M1.21%0Timeline
GOSSGOSSAMER BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,665,010 shares; 2024Q4: 4,490,000 shares; 2025Q1: 4,287,415 shares; 2025Q2: 3,545,000 shares; 2025Q3: 2,725,000 shares; 2025Q4: 2,720,000 shares 2,720,000$8.43M1.11%-5,000Timeline
MBXMBX BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 250,000 shares; 2025Q2: 239,319 shares; 2025Q3: 253,000 shares; 2025Q4: 260,000 shares 260,000$8.2M1.08%+7,000Timeline
RVMDREVOLUTION MEDICINES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 105,000 shares; 2025Q3: 100,000 shares; 2025Q4: 100,000 shares 100,000$7.96M1.05%0Timeline
XOMAXOMA ROYALTY CORPORATIONQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 250,000 shares; 2024Q4: 250,000 shares; 2025Q1: 253,043 shares; 2025Q2: 255,087 shares; 2025Q3: 255,087 shares; 2025Q4: 292,590 shares 292,590$7.78M1.03%+37,503Timeline
DERMJOURNEY MED CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 69,323 shares; 2025Q2: 95,000 shares; 2025Q3: 971,064 shares; 2025Q4: 975,000 shares 975,000$7.52M0.99%+3,936Timeline
KPTIKARYOPHARM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 930,000 shares 930,000$6.84M0.9%newTimeline
JBIOJADE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 427,608 shares 427,608$6.6M0.87%newTimeline
URGNUROGEN PHARMA LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 404,100 shares; 2024Q4: 220,000 shares; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 268,423 shares 268,423$6.29M0.83%newTimeline
ALMSALUMIS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 775,000 shares; 2025Q3: 665,000 shares; 2025Q4: 535,000 shares 535,000$5.22M0.69%-130,000Timeline
CATXPERSPECTIVE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,184,500 shares 1,184,500$4.99M0.66%newTimeline
VYGRVOYAGER THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,196,904 shares 1,196,904$4.7M0.62%newTimeline
RLMDRELMADA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 480,000 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 935,000 shares 935,000$4.52M0.6%newTimeline
TECXTECTONIC THERAPEUTIC INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 214,747 shares 214,747$4.48M0.59%newTimeline
PLXPROTALIX BIOTHERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 2,580,556 shares; 2025Q4: 2,478,176 shares 2,478,176$4.46M0.59%-102,380Timeline
TRVITREVI THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,567,990 shares; 2024Q4: 2,317,500 shares; 2025Q1: 795,000 shares; 2025Q2: 390,000 shares; 2025Q3: 390,000 shares; 2025Q4: 345,100 shares 345,100$4.32M0.57%-44,900Timeline
FBIOFORTRESS BIOTECH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,090,000 shares 1,090,000$3.99M0.53%newTimeline
RCKTROCKET PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 955,000 shares 955,000$3.35M0.44%newTimeline
MGTXMEIRAGTX HLDGS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 390,844 shares 390,844$3.11M0.41%newTimeline
RIGLRIGEL PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 37,787 shares; 2025Q4: 70,000 shares 70,000$3M0.4%+32,213Timeline
ZYMEZYMEWORKS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 175,000 shares; 2025Q2: 210,000 shares; 2025Q3: 100,000 shares; 2025Q4: 108,929 shares 108,929$2.87M0.38%+8,929Timeline
ASSERTIO HOLDINGS INCASSERTIO HOLDINGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 285,000 shares 285,000$2.58M0.34%new
VTYXVENTYX BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 280,000 shares; 2025Q1: 190,000 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 251,932 shares 251,932$2.27M0.3%newTimeline
IRDOPUS GENETICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 1,175,000 shares; 2025Q2: 1,220,000 shares; 2025Q3: 1,100,000 shares; 2025Q4: 1,120,000 shares 1,120,000$2.25M0.3%+20,000Timeline
STROSUTRO BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 190,671 shares 190,671$2.21M0.29%newTimeline
CABACABALETTA BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 808,882 shares; 2025Q4: 900,000 shares 900,000$1.97M0.26%+91,118Timeline
ZNTLZENTALIS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 967,000 shares; 2024Q4: 1,767,500 shares; 2025Q1: 1,985,000 shares; 2025Q2: 1,924,300 shares; 2025Q3: 316,550 shares; 2025Q4: 1,400,906 shares 1,400,906$1.89M0.25%+1,084,356Timeline
GENERATION BIO COGENERATION BIO COQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 310,000 shares 310,000$1.76M0.23%new
BBIOBRIDGEBIO PHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 18,319 shares 18,319$1.4M0.18%newTimeline
ENTAENANTA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 75,000 shares 75,000$1.18M0.16%newTimeline
QTTBQ32 BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 213,363 shares 213,363$708K0.09%newTimeline
AVIRATEA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 179,815 shares 179,815$642K0.08%newTimeline
SLNSILENCE THERAPEUTICS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 78,926 shares 78,926$480K0.06%newTimeline
RAPTRAPT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 150,000 shares 150,000$213K0.03%newTimeline
ADGMADAGIO MED HLDGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 110,571 shares; 2024Q4: 110,571 shares; 2025Q1: 110,571 shares; 2025Q2: 110,571 shares; 2025Q3: 110,571 shares; 2025Q4: 18,444 shares 18,444$19.2K<0.01%-92,127Timeline

Sold out in Q4 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
IMNMIMMUNOME INC3,185,000$37.3Mshares
SRPTSAREPTA THERAPEUTICS INC585,000$11.3Mshares
LRMRLARIMAR THERAPEUTICS INC3,720,867$10.6Mshares
ARVNARVINAS INC987,818$8.42Mshares
TMCITREACE MED CONCEPTS INC702,245$4.71Mshares
KARYOPHARM THERAPEUTICS INCKARYOPHARM THERAPEUTICS INC6,000,000$4.63Mprincipal
ADCTADC THERAPEUTICS SA682,529$2.73Mshares
SYRESPYRE THERAPEUTICS INC65,000$1.09Mshares
PEPGPEPGEN INC75,000$346Kshares
IBIOIBIO INC375,000$310Kshares

How Q4 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001493152-26-007085 superseded2026-02-17acceptance time not in the bulk data set
13F-HR/A 0001493152-26-016299 baserestatement2026-04-13acceptance time not in the bulk data set