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Disclosery

CBIO CRESCENT BIOPHARMA INC.

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COMMON STOCK (common), issuer CIK 1253689

77 managers (80 13F filers) reported a position in CBIO shares at 2026-06-30, 29,113,818 shares in all. 32 filers opened a position and 12 filers sold out during the quarter.

Managers
77
13F filers
80
New
32
Added
17
Reduced
14
Sold out
12
Shares held by filers
29,113,818

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC4,133,514$74.4M<0.01%013F-HRTimelineGroup
BVF INC/ILin group BVF INC/IL2,748,763$49.5M1.27%013F-HRTimelineGroup
Fairmount Funds Management LLC2,747,866$49.5M3.27%013F-HRTimeline
Venrock Adviser, LLC2,133,576$38.4M1.16%013F-HRTimeline
Logos Global Management LP1,900,000$34.2M1.47%+1,417,50013F-HRTimeline
FCPM III SERVICES B.V.in group FCPM III SERVICES B.V.1,677,852$30.2M4.02%013F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management1,662,917$29.9M0.05%+152,88413F-HRTimelineGroup
Vestal Point Capital, LP1,630,000$29.3M0.69%+130,00013F-HRTimeline
Opaleye Management Inc.1,319,351$23.7M2.15%+6,73613F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.1,271,762$22.9M<0.01%+1,156,03713F-HRTimelineGroup
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC1,160,000$20.9M0.95%013F-HRTimelineGroup
VANGUARD GROUP INCgroup of 4 filers holding1,034,497$18.6M+180,210Timeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC403,859$7.27M<0.01%+80,30613F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC384,576$6.92M<0.01%+280,35513F-HRTimelineGroup
JENNISON ASSOCIATES LLC378,507$6.81M<0.01%+225,53313F-HRTimeline
RTW INVESTMENTS, LP372,856$6.71M0.06%013F-HRTimeline
NEXTBio Capital Management LP372,856$6.71M3.09%013F-HRTimeline
Remedium Capital Partners, LLC361,250$6.5M1.44%new13F-HRTimeline
STATE STREET CORPin group STATE STREET CORP315,587$5.68M<0.01%+276,52013F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC302,568$5.45M<0.01%new13F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.300,000$5.4M0.01%013F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/275,581$4.96M<0.01%-27,97013F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP214,300$3.86M<0.01%+13,52013F-HRTimelineGroup
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC206,942$3.72M0.06%013F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP186,874$3.36M<0.01%+71,04613F-HRTimelineGroup
STEMPOINT CAPITAL LP182,382$3.28M0.57%new13F-HRTimeline
UBS Group AGin group UBS Group AG175,182$3.15M<0.01%+92,47613F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP138,778$2.5M<0.01%+121,54913F-HRTimelineGroup
Exome Asset Management LLC127,769$2.3M1.42%-25,42213F-HRTimeline
SECTORAL ASSET MANAGEMENT INC121,300$2.18M1.52%new13F-HRTimeline
Woodline Partners LP94,488$1.7M0.01%+20,48813F-HRTimeline
Burkehill Global Management, LP74,000$1.33M0.05%013F-HRTimeline
Blackstone Inc.in group Blackstone Inc.62,647$1.13M<0.01%new13F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…59,104$1.06M0.12%-71,39613F-HRTimelineGroup
Y-Intercept (Hong Kong) Ltd50,824$915K0.02%new13F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co50,258$905K<0.01%new13F-HRTimelineGroup
Nuveen, LLCin group TIAA47,629$857K<0.01%new13F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp45,778$824K<0.01%new13F-HRTimelineGroup
Stonepine Capital Management, LLC40,000$720K0.55%-45,00013F-HR/ATimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/25,821$465K<0.01%-3,45613F-HRTimelineGroup
RHUMBLINE ADVISERS25,487$459K<0.01%new13F-HRTimeline
MOORE CAPITAL MANAGEMENT, LP25,000$450K0.01%013F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC24,166$435K<0.01%new13F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC22,805$410K<0.01%new13F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN19,700$355K<0.01%new13F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC18,275$329K0.02%-31,99813F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…18,258$329K0.08%new13F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …17,755$320K<0.01%-7,14813F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY17,698$319K<0.01%-87913F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…14,600$263K<0.01%new13F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/13,768$248K<0.01%new13F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…12,780$230K<0.01%new13F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.11,731$211K<0.01%new13F-HRTimelineGroup
Persistent Asset Partners Ltd10,968$197K0.06%new13F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd10,564$190K<0.01%new13F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC10,141$183K<0.01%-10,02813F-HRTimelineGroup
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…9,901$178K<0.01%new13F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO9,020$162K<0.01%-31,98413F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND7,600$137K<0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…6,369$115K<0.01%new13F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC4,462$80.3K<0.01%-25,72713F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS3,303$59.5K<0.01%-12,39113F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc2,097$37.7K<0.01%new13F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,761$31.7K<0.01%new13F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…1,726$31.1K<0.01%new13F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA681$12K<0.01%+63013F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\403$7.25K<0.01%new13F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…297$5.35K<0.01%new13F-HR/ATimeline
Parallel Advisors, LLC264$4.75K<0.01%013F-HRTimeline
Allworth Financial LP161$2.9K<0.01%013F-HRTimeline
Sterling Capital Management LLC76$1.37K<0.01%new13F-HRTimeline
SBI Securities Co., Ltd.68$1.22K<0.01%013F-HRTimeline
Fortitude Family Office, LLC40$720<0.01%013F-HRTimeline
Quarry LP29$522<0.01%new13F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.26$468<0.01%013F-HRTimelineGroup
Caitong International Asset Management …21$378<0.01%+1713F-HRTimeline
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/3$54<0.01%new13F-HRTimelineGroup