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Disclosery

STOK STOKE THERAPEUTICS INC

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COM (common), issuer CIK 1623526

180 managers (183 13F filers) reported a position in STOK shares at 2025-12-31, 66,984,195 shares in all. 42 filers opened a position and 13 filers sold out during the quarter.

Managers
180
13F filers
183
New
42
Added
54
Reduced
58
Sold out
13
Shares held by filers
66,984,195

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

Each filer's latest stake. The shares are the aggregate the reporting persons state, which can include entities that file no 13F.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC5,600,920$178M0.01%-1,264,13713F-HRTimelineGroup
RTW INVESTMENTS, LP5,546,856$176M1.76%+423,33113F-HRTimeline
Lynx1 Capital Management LPin group Lynx1 Capital Management LP5,404,674$172M34.73%013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.5,212,554$165M<0.01%-774,88713F-HRTimelineGroup
Redmile Group, LLCin group Redmile Group, LLC4,034,070$128M9.43%-141,47213F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY3,546,158$113M0.01%+9,10813F-HR/ATimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP3,336,697$106M0.62%-1,297,14113F-HRTimelineGroup
TORONTO DOMINION BANKin group TORONTO DOMINION BANK3,173,258$101M0.18%013F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC3,149,239$100M<0.01%-14,63513F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP2,498,049$79.3M<0.01%+1,072,17613F-HRTimelineGroup
BVF INC/ILin group BVF INC/IL2,265,674$71.9M2.42%+608,57813F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.2,247,347$71.3M2.13%013F-HRTimelineGroup
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…1,823,500$57.9M0.74%new13F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson1,450,933$46M0.02%+1,116,45213F-HRTimelineGroup
Polar Capital Holdings Plcin group Polar Capital Holdings Plc1,269,131$40.3M0.18%-54,33913F-HRTimelineGroup
Assenagon Asset Management S.A.1,227,723$39M0.06%+327,45113F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.1,222,213$38.8M0.06%-84,48513F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,166,145$37M<0.01%+19,14513F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC1,142,737$36.3M0.01%-8,19213F-HR/ATimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP827,139$26.3M0.01%+148,83213F-HRTimelineGroup
MPM BIOIMPACT LLC770,289$24.4M2.8%-19,40913F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…735,799$23.4M<0.01%-1,95413F-HRTimelineGroup
Opaleye Management Inc.695,000$22.1M2.91%+12,98313F-HR/ATimeline
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC500,000$15.9M0.78%013F-HRTimelineGroup
Candriam S.C.A.446,690$14.2M0.07%new13F-HR/ATimeline
Parkman Healthcare Partners LLC430,155$13.7M1.3%+180,15513F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co410,906$13M<0.01%+7,99713F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP403,168$12.8M<0.01%-11,74913F-HRTimelineGroup
Erste Asset Management GmbHin group Erste Asset Management GmbH396,000$12.6M0.11%013F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/372,334$11.8M<0.01%+321,07113F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO277,930$8.82M<0.01%+253,55413F-HRTimelineGroup
Birchview Capital, LP260,000$8.25M4.83%+50,00013F-HRTimeline
Invesco Ltd.in group Invesco Ltd.259,543$8.24M<0.01%+51,46813F-HRTimelineGroup
BAILLIE GIFFORD & COin group BAILLIE GIFFORD & CO246,900$7.84M0.01%new13F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding226,925$7.2M-154,970Timeline
Rhenman & Partners Asset Management AB216,000$6.86M0.64%-34,00013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/206,164$6.54M<0.01%-43,28713F-HRTimelineGroup
Granahan Investment Management, LLC191,397$6.07M0.26%-62,50213F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding172,372$5.47M+19,230Timeline
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP162,679$5.16M<0.01%+10,38013F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC150,945$4.79M<0.01%+43,22213F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp140,802$4.47M<0.01%+20,36613F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources132,222$4.2M<0.01%+16,38913F-HRTimelineGroup
GILDER GAGNON HOWE & CO LLC122,448$3.89M0.04%-32,71813F-HRTimeline
Informed Momentum Co LLC117,823$3.74M0.42%-2,35813F-HRTimeline
HighVista Strategies LLC115,539$3.67M0.94%new13F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC115,118$3.65M<0.01%+16,02613F-HRTimelineGroup
DAFNA Capital Management LLC108,875$3.46M0.8%-60,91613F-HRTimeline
Nuveen, LLCin group TIAA104,261$3.31M<0.01%-1,73313F-HRTimelineGroup
Rafferty Asset Management, LLC90,193$2.86M0.01%+54,86613F-HRTimeline
Penserra Capital Management LLCin group Penserra Capital Management L…88,507$2.81M0.03%-62,09213F-HRTimelineGroup
Quantedge Capital Pte Ltd87,200$2.77M1.32%+47,20013F-HRTimeline
Swiss National Bank75,700$2.4M<0.01%+1,60013F-HRTimeline
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.75,000$2.38M0.01%new13F-HRTimelineGroup
Palo Alto Investors LP72,022$2.29M0.32%-33,40513F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC70,282$2.23M<0.01%+25,07713F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC67,112$2.13M<0.01%new13F-HRTimelineGroup
ALPS ADVISORS INCin group ALPS ADVISORS INC66,502$2.11M0.01%+21,83813F-HRTimelineGroup
Schonfeld Strategic Advisors LLC63,109$2M0.01%-174,90613F-HRTimeline
HUSSMAN STRATEGIC ADVISORS, INC.63,000$2M0.48%new13F-HRTimeline
RHUMBLINE ADVISERS62,414$1.98M<0.01%-5,89013F-HRTimeline
Privium Fund Management B.V.55,000$1.75M0.32%new13F-HRTimeline
Woodline Partners LP50,120$1.59M0.01%-45,00013F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.49,901$1.58M<0.01%-2,71213F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN49,585$1.57M<0.01%+21,51413F-HRTimelineGroup
NOMURA HOLDINGS INCin group NOMURA ASSET MANAGEMENT CO LTD44,352$1.41M<0.01%-36,85713F-HRTimelineGroup
Creative Planningin group Creative Planning41,712$1.32M<0.01%-1,59213F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC41,140$1.31M<0.01%new13F-HRTimeline
PLATINUM INVESTMENT MANAGEMENT LTD40,815$1.3M0.3%+7,91413F-HRTimeline
ALLIANCEBERNSTEIN L.P.40,630$1.29M<0.01%013F-HRTimeline
Kennondale Capital Management LLC38,731$1.23M0.9%-31,00113F-HRTimeline
Harvest Investment Services, LLC38,347$1.22M0.23%new13F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…37,127$1.18M<0.01%+5,05713F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc36,366$1.15M<0.01%-1,41713F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding35,291$1.12M-17,290Timeline
CANADA PENSION PLAN INVESTMENT BOARD35,200$1.12M<0.01%new13F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\33,406$1.06M<0.01%+9,17613F-HRTimelineGroup
PROFUND ADVISORS LLC33,388$1.06M0.03%new13F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC29,467$935K<0.01%+35413F-HRTimelineGroup
READYSTATE ASSET MANAGEMENT LP29,059$922K0.04%new13F-HRTimeline
Cresset Asset Management, LLC26,325$836K<0.01%-41113F-HRTimeline
SG Americas Securities, LLC25,836$820K<0.01%+16,84013F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…25,320$804K<0.01%013F-HRTimelineGroup
Allspring Global Investments Holdings, …in group Allspring Global Investments …24,462$756K<0.01%-10,59613F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC21,076$669K<0.01%+8013F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL19,309$613K<0.01%new13F-HRTimeline
MASSACHUSETTS FINANCIAL SERVICES CO /MA/in group MASSACHUSETTS FINANCIAL SERVI…19,101$606K<0.01%new13F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC18,652$592K0.01%+5,50513F-HRTimeline
DIADEMA PARTNERS LP17,181$545K0.32%new13F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO16,631$528K<0.01%+18113F-HRTimelineGroup
PSP Research LLC16,621$528K0.46%13F-HRTimeline
AVIVA PLCin group AVIVA PLC15,871$504K<0.01%-6,44713F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC15,851$503K<0.01%-58,20513F-HRTimelineGroup
AlphaQuest LLC15,036$477K0.03%-5913F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND15,035$477K<0.01%013F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD14,819$470K<0.01%new13F-HRTimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co14,768$469K<0.01%+2,79013F-HRTimelineGroup
SIMPLEX TRADING, LLC14,281$453K0.01%new13F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC14,134$447K<0.01%new13F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC13,603$432K<0.01%+7,08813F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …13,550$430K<0.01%-1,49413F-HRTimelineGroup
Campbell & CO Investment Adviser LLC12,995$412K0.02%-17,42313F-HRTimeline
China Universal Asset Management Co., L…12,907$410K0.03%+3,30213F-HRTimeline
JACOBS LEVY EQUITY MANAGEMENT, INC12,878$409K<0.01%-2,20713F-HRTimeline
Police & Firemen's Retirement System of…12,535$398K<0.01%+11413F-HRTimeline
Entropy Technologies, LP11,764$373K0.02%new13F-HRTimeline
CAPITAL FUND MANAGEMENT S.A.11,717$372K<0.01%new13F-HRTimeline
Quantinno Capital Management LP11,088$352K<0.01%new13F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM10,936$347K<0.01%-35813F-HRTimeline
Dorsey & Whitney Trust CO LLC10,815$343K0.02%013F-HRTimeline
ProShare Advisors LLC10,721$340K<0.01%+1,09913F-HRTimeline
NewEdge Advisors, LLC10,403$330K<0.01%new13F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.10,260$326K<0.01%+5513F-HRTimelineGroup
Vestcor Inc10,171$323K0.01%013F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management9,340$296K<0.01%new13F-HRTimelineGroup
LOS ANGELES CAPITAL MANAGEMENT LLC9,206$292K<0.01%-5713F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…9,129$290K<0.01%013F-HRTimeline
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/9,055$287K<0.01%new13F-HRTimelineGroup
FARALLON CAPITAL MANAGEMENT, L.L.C.9,000$286K<0.01%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
Tidal Investments LLCin group Tidal Investments LLC8,355$265K<0.01%new13F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…8,214$261K0.07%-1,41313F-HRTimelineGroup
KLP KAPITALFORVALTNING AS8,200$260K<0.01%-1,40013F-HRTimeline
Dynamic Technology Lab Private Ltd8,054$256K0.06%-5,57613F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC7,761$246K<0.01%new13F-HRTimelineGroup
LPL Financial LLC7,380$234K<0.01%new13F-HRTimeline
GSA CAPITAL PARTNERS LLP7,076$225K0.02%-40,50713F-HRTimeline
STRS OHIO7,000$222K<0.01%+60013F-HRTimeline
J. Goldman & Co LP6,827$217K0.01%new13F-HRTimeline
Swiss Life Asset Management Ltdin group Swiss Life Asset Management L…6,798$216K<0.01%new13F-HRTimelineGroup
VIRGINIA RETIREMENT SYSTEMS ET Al6,550$208K<0.01%new13F-HRTimeline
PRELUDE CAPITAL MANAGEMENT, LLC6,369$202K0.01%new13F-HRTimeline
Persistent Asset Partners Ltd4,576$145K0.07%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS4,257$135K<0.01%-9,14413F-HRTimelineGroup
GROUP ONE TRADING LLC4,110$130K<0.01%new13F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…3,748$119K<0.01%013F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…3,617$115K<0.01%-21413F-HRTimelineGroup
Cygnus Capital Advisors, LLC3,000$95K0.07%13F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP2,570$81.6K<0.01%-73013F-HRTimelineGroup
Generali Investments, Management Co LLC2,471$78.4K0.02%+71813F-HRTimeline
NISA INVESTMENT ADVISORS, LLC2,436$77.3K<0.01%-29613F-HRTimeline
CFG Wealth Management Services, Inc.2,230$70.8K0.06%13F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA1,623$52K<0.01%-914,16313F-HRTimelineGroup
Versant Capital Management, Inc1,592$50.5K0.01%013F-HRTimeline
AMALGAMATED BANK1,409$45K<0.01%+16913F-HRTimeline
HARBOUR INVESTMENTS, INC.1,185$37.6K<0.01%+89813F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,121$35.6K<0.01%-5813F-HRTimeline
State of Wyoming1,110$35.2K<0.01%-6,73413F-HRTimeline
GAMMA Investing LLC830$26.3K<0.01%+15013F-HRTimeline
Kestra Advisory Services, LLCin group Kestra Advisory Services, LLC818$26K<0.01%new13F-HRTimelineGroup
VALLEY NATIONAL ADVISERS INC750$23K<0.01%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…630$20K<0.01%-53013F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…622$19.7K<0.01%+60513F-HRTimelineGroup
CWM, LLCin group CWM, LLC565$18K<0.01%+1713F-HRTimelineGroup
Stone House Investment Management, LLC500$15.9K<0.01%013F-HRTimeline
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …476$15K<0.01%+15913F-HRTimelineGroup
MONTAG A & ASSOCIATES INC440$14K<0.01%013F-HRTimeline
Wilmington Savings Fund Society, FSB400$12.7K<0.01%013F-HRTimeline
Sterling Capital Management LLC298$9.46K<0.01%+18913F-HRTimeline
ROTHSCHILD INVESTMENT LLC293$9.3K<0.01%+313F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\244$7.75K<0.01%013F-HRTimelineGroup
Prestige Wealth Management Group LLC200$6.35K<0.01%new13F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.175$6K<0.01%013F-HRTimelineGroup
Smartleaf Asset Management LLC155$4.93K<0.01%new13F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.142$4.51K<0.01%-21213F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…98$3.11K<0.01%new13F-HR/ATimelineGroup
J.Safra Asset Management Corp97$3.08K<0.01%-3713F-HRTimeline
Larson Financial Group LLC92$2.92K<0.01%-2213F-HRTimeline
Quantbot Technologies LP88$2.79K<0.01%new13F-HRTimeline
SIGNATUREFD, LLC83$2.63K<0.01%013F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…44$1.4K<0.01%013F-HRTimelineGroup
Rachor Investment Advisory Services, LLC40$1.27K<0.01%13F-HRTimeline
Global Retirement Partners, LLC35$1.11K<0.01%013F-HRTimeline
Arax Advisory Partners21$667<0.01%-15613F-HRTimeline
Farther Finance Advisors, LLC18$571<0.01%+113F-HRTimeline
Parallel Advisors, LLC13$413<0.01%new13F-HRTimeline
Allworth Financial LP7$223<0.01%+513F-HRTimeline
Root Financial Partners, LLC7$222<0.01%new13F-HRTimeline
IFP Advisors, Inc5$159<0.01%013F-HRTimeline
SBI Securities Co., Ltd.5$159<0.01%-5113F-HRTimeline
True Wealth Design, LLC4$127<0.01%013F-HRTimeline

Events

  • BIOTECHNOLOGY VALUE FUND L P and 9 other reporting persons reported 3,608,968 STOK shares, 5.6% of the class, as of 2026-09-23, in a 13G filed 2026-09-30. 0000921895-26-002685

    Accepted , ingested