13F-HR filed by TANG CAPITAL MANAGEMENT LLC
TANG CAPITAL MANAGEMENT LLC filed this 13F-HR for the quarter ended 2025-12-31, filed 2026-02-17, with 75 holding rows worth $2,024,360,609.
- Accession
- 0001214659-26-002015
- Filer
- CIK 1232621
- Filed
- 2026-02-17
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2025
A holdings report, 75 entries on the cover page, a total value of $2,024,360,609 stated on the cover page (in dollars after the unit check, H1), rows summing to $2,024,360,609 with VALUE read as dollars as filed, 13F file number 028-14822. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerTANG KEVIN028-14818
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| AURINIA PHARMACEUTICALS INC COM | 05156V102 | Stock | 11,329,500 | $180,705,525 | dollars as filed | |
| LAKEFRONT BIOTHERAPEUTICS NV | 36315X101 | SPON ADR | 3,921,219 | $128,223,861 | dollars as filed | |
| PTC THERAPEUTICS INC | 69366J200 | COM | 1,500,000 | $113,940,000 | dollars as filed | |
| CELCUITY INC | 15102K100 | COM | 1,050,000 | $104,727,000 | dollars as filed | |
| MIRUM PHARMACEUTICALS INC | 604749101 | COM | 1,236,027 | $97,633,773 | dollars as filed | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 1,188,624 | $97,324,533 | dollars as filed | |
| KINIKSA PHARMACEUTICALS INTL P ORD SHS CL A | G52694109 | Stock | 2,259,889 | $93,220,421 | dollars as filed | |
| IMMUNOCORE HLDGS PLC ADS | 45258D105 | ADR | 2,628,538 | $91,236,554 | dollars as filed | |
| COMPASS THERAPEUTICS INC | 20454B104 | COM | 16,790,809 | $90,166,644 | dollars as filed | |
| KALVISTA PHARMACEUTICALS INC | 483497103 | COM | 4,573,530 | $73,862,510 | dollars as filed | |
| AVIDITY BIOSCIENCES INC COM | 05370A108 | Stock | 900,000 | $64,917,000 | dollars as filed | |
| ANAPTYSBIO INC | 032724106 | COM | 1,332,087 | $64,579,578 | dollars as filed | |
| SPYRE THERAPEUTICS INC | 00773J202 | COM NEW | 1,892,200 | $61,988,472 | dollars as filed | |
| VIRIDIAN THERAPEUTICS INC | 92790C104 | COM | 1,792,626 | $55,786,521 | dollars as filed | |
| CAPRICOR THERAPEUTICS INC | 14070B309 | COMMON STOCK | 1,700,000 | $49,062,000 | dollars as filed | |
| BIONTECH SE SPONSORED ADS | 09075V102 | ADR | 470,000 | $44,744,000 | dollars as filed | |
| ANI PHARMACEUTICALS INC | 00182C103 | COM | 481,437 | $38,004,637 | dollars as filed | |
| Vertex Pharmaceuticals Incorporated | 92532F100 | COM | 80,000 | $36,268,800 | dollars as filed | |
| NUVATION BIO INC COM CL A | 67080N101 | Stock | 3,857,457 | $34,562,815 | dollars as filed | |
| TRAVERE THERAPEUTICS INC | 89422G107 | COM | 700,000 | $26,747,000 | dollars as filed | |
| Ventyx Biosciences Inc | 92332V107 | Common Stock | 2,814,000 | $25,410,420 | dollars as filed | |
| NVIDIA Corp | 67066G104 | COM | 127,788 | $23,832,462 | dollars as filed | |
| PRECIGEN INC | 74017N105 | COM | 5,617,500 | $23,481,150 | dollars as filed | |
| SPY | 78462F103 | SHS | 30,000 | $20,457,600 | dollars as filed | |
| MODERNA INC | 60770K107 | COM | 692,820 | $20,431,262 | dollars as filed | |
| VIKING THERAPEUTICS INC | 92686J106 | COM | 500,000 | $17,590,000 | dollars as filed | |
| ATEA PHARMACEUTICALS INC | 04683R106 | COMMON STOCK | 4,814,700 | $17,188,479 | dollars as filed | |
| STOKE THERAPEUTICS INC | 86150R107 | COM | 500,000 | $15,870,000 | dollars as filed | |
| IDEAYA BIOSCIENCES INC COM | 45166A102 | Stock | 450,000 | $15,556,500 | dollars as filed | |
| META PLATFORMS INC CL A | 30303M102 | COM | 23,331 | $15,400,560 | dollars as filed | |
| GSK PLC SPONSORED ADR | 37733W204 | ADR | 300,000 | $14,712,000 | dollars as filed | |
| JOURNEY MED CORP | 48115J109 | COM | 1,854,596 | $14,298,935 | dollars as filed | |
| LENZ THERAPEUTICS INC | 52635N103 | COM | 865,169 | $13,842,704 | dollars as filed | |
| VAXCYTE INC COM | 92243G108 | Stock | 275,000 | $12,688,500 | dollars as filed | |
| DIANTHUS THERAPEUTICS INC | 252828108 | COM | 264,692 | $10,907,958 | dollars as filed | |
| HARMONY BIOSCIENCES HLDGS IN | 413197104 | COM | 290,292 | $10,862,727 | dollars as filed | |
| Bristol-Myers Squibb Company | 110122108 | COM | 200,000 | $10,788,000 | dollars as filed | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 60,000 | $10,442,400 | dollars as filed | |
| CRESCENT BIOPHARMA INC | G2545C104 | COMMON STOCK | 872,398 | $10,346,640 | dollars as filed | |
| WAVE LIFE SCIENCES LTD SHS | Y95308105 | Stock | 600,000 | $10,200,000 | dollars as filed | |
| TELADOC HEALTH INC | 87918A105 | COM | 1,400,000 | $9,800,000 | dollars as filed | |
| DYNAVAX TECHNOLOGIES CORP | 268158201 | COM NEW | 556,359 | $8,556,801 | dollars as filed | |
| EVOLUS INC | 30052C107 | COM | 1,245,692 | $8,283,852 | dollars as filed | |
| VERASTEM INC | 92337C203 | COMMON STOCK | 1,069,810 | $8,258,933 | dollars as filed | |
| UROGEN PHARMA LTD | M96088105 | COMMON STOCK | 350,000 | $8,197,000 | dollars as filed | |
| HERON THERAPEUTICS INC | 427746102 | COM | 6,250,000 | $8,125,000 | dollars as filed | |
| ACADIA PHARMACEUTICALS INC | 004225108 | COM | 300,000 | $8,013,000 | dollars as filed | |
| ALTIMMUNE INC | 02155H200 | COM NEW | 2,131,307 | $7,694,018 | dollars as filed | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 349,220 | $7,515,214 | dollars as filed | |
| PLIANT THERAPEUTICS INC | 729139105 | COM | 6,143,132 | $7,494,621 | dollars as filed | |
| ARVINAS INC | 04335A105 | COM | 569,698 | $6,756,618 | dollars as filed | |
| THERAVANCE BIOPHARMA INC | G8807B106 | COM | 351,252 | $6,571,925 | dollars as filed | |
| BIOCRYST PHARMACEUTICALS INC COM | 09058V103 | Stock | 800,000 | $6,240,000 | dollars as filed | |
| PMV PHARMACEUTICALS INC | 69353Y103 | COM | 4,940,000 | $6,175,000 | dollars as filed | |
| REGENERON PHARMACEUTICALS COM | 75886F107 | Stock | 8,000 | $6,174,960 | dollars as filed | |
| BIOGEN INC COM | 09062X103 | Stock | 35,000 | $6,159,650 | dollars as filed | |
| CORCEPT THERAPEUTICS INC | 218352102 | COM | 156,764 | $5,455,387 | dollars as filed | |
| ABEONA THERAPEUTICS INC | 00289Y206 | COM NEW | 1,000,000 | $5,270,000 | dollars as filed | |
| IMMUNITYBIO INC | 45256X103 | COM | 2,333,333 | $4,619,999 | dollars as filed | |
| KEZAR LIFE SCIENCES INC | 49372L209 | COM NEW | 664,314 | $4,178,535 | dollars as filed | |
| COHERUS ONCOLOGY INC | 19249H103 | COM | 2,724,509 | $3,868,803 | dollars as filed | |
| ERASCA INC COM | 29479A108 | Stock | 900,000 | $3,348,000 | dollars as filed | |
| NKARTA INC | 65487U108 | COMMON STOCK | 1,480,823 | $2,739,523 | dollars as filed | |
| NUVALENT INC COM | 670703107 | Stock | 21,880 | $2,200,909 | dollars as filed | |
| ALEXANDRIA REAL ESTATE EQ INC COM | 015271109 | REIT | 40,000 | $1,957,600 | dollars as filed | |
| NEUMORA THERAPEUTICS INC. | 640979100 | COM | 967,235 | $1,731,351 | dollars as filed | |
| SUTRO BIOPHARMA INC | 869367201 | COMMON STOCK | 139,617 | $1,615,369 | dollars as filed | |
| BIOHAVEN LTD | G1110E107 | COM | 140,000 | $1,580,600 | dollars as filed | |
| REVOLUTION MEDICINES INC COM | 76155X100 | Stock | 15,640 | $1,245,726 | dollars as filed | |
| FATE THERAPEUTICS INC | 31189P102 | COM | 1,167,773 | $1,147,454 | dollars as filed | |
| ZYMEWORKS INC | 98985Y108 | COM | 34,631 | $911,834 | dollars as filed | |
| ROCKET PHARMACEUTICALS INC | 77313F106 | COM | 100,000 | $351,000 | dollars as filed | |
| ADICET BIO INC | 007002207 | COM NEW | 6,158 | $51,850 | dollars as filed | |
| Tscan Therapeutics Inc | 89854M101 | COM | 46,131 | $46,131 | dollars as filed | |
| FILANA THERAPEUTICS INC | 14817C107 | CMN | 7,073 | $14,005 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001214659-26-002015 | this filing | 2026-02-17 | acceptance time not in the bulk data set |