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Disclosery

SION SIONNA THERAPEUTICS INC

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COMMON STOCK (common), issuer CIK 2036042

117 managers (122 13F filers) reported a position in SION shares at 2026-03-31, 45,407,312 shares in all. 28 filers opened a position and 9 filers sold out during the quarter.

Managers
117
13F filers
122
New
28
Added
40
Reduced
30
Sold out
9
Shares held by filers
45,407,312

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2026

Filers in the available 13F reports with a share position at 2026-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.9,905,045$397M4.21%013F-HRTimelineGroup
TPG GP A, LLCin group TPG GP A, LLC6,494,962$260M7.08%-250,00013F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC3,530,702$142M3.09%-30,95313F-HRTimelineGroup
VIKING GLOBAL INVESTORS LPin group VIKING GLOBAL INVESTORS LP3,195,181$128M0.36%013F-HRTimelineGroup
Atlas Venture Life Science Advisors, LLC2,995,602$120M15.2%013F-HRTimeline
ENAVATE SCIENCES GP, LLC2,478,030$99.3M28.26%013F-HRTimeline
JENNISON ASSOCIATES LLC1,451,220$58.2M0.04%+335,94213F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO1,465,014$53.7M<0.01%+233,19513F-HR/ATimelineGroup
BlackRock, Inc.in group BlackRock, Inc.1,295,867$52M<0.01%+4,26813F-HRTimelineGroup
VANGUARD GROUP INCgroup of 4 filers holding1,294,944$51.9MnewTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC1,166,931$46.8M0.03%+79,60613F-HRTimelineGroup
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…970,590$38.9M0.46%013F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/756,376$30.3M<0.01%-74,99713F-HRTimeline
STATE STREET CORPin group STATE STREET CORP756,227$30.3M<0.01%+62,83213F-HRTimelineGroup
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC658,439$26.4M0.52%-520,65913F-HR/ATimelineGroup
EVENTIDE ASSET MANAGEMENT, LLC645,530$25.9M0.43%+6,48513F-HRTimeline
Aberdeen Group plcin group Aberdeen Group plc564,175$22.6M0.04%-275,78513F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP400,000$16M0.09%013F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC389,872$15.6M<0.01%+9,83013F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.300,000$12M0.33%013F-HRTimelineGroup
Sio Capital Management, LLC294,340$11.8M1.7%new13F-HRTimeline
Soleus Capital Management, L.P.293,500$11.8M0.48%+25,00013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC263,174$10.6M<0.01%+226,90513F-HRTimelineGroup
Ensign Peak Advisors, Inc255,636$10.2M0.02%+175,77413F-HR/ATimeline
Candriam S.C.A.236,813$9.49M0.05%new13F-HRTimeline
Kalehua Capital Management LLC197,072$7.9M5.59%013F-HR/ATimeline
FRANKLIN RESOURCES INCin group Franklin Resources175,483$7.04M<0.01%013F-HRTimelineGroup
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…150,000$6.01M0.01%new13F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding147,757$5.92M+58,580Timeline
SUPERSTRING CAPITAL MANAGEMENT LP141,024$5.65M4.04%-39,56913F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC140,641$5.64M<0.01%+60,09513F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.136,549$5.47M0.01%new13F-HRTimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.136,222$5.46M0.02%013F-HRTimelineGroup
GordonMD Global Investments LPin group GordonMD Global Investments LP136,000$5.45M3.8%new13F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY133,023$5.33M<0.01%+83,14713F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co120,253$4.82M<0.01%-3,43313F-HRTimelineGroup
Artia Global Partners LP119,741$4.8M1.08%013F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP116,776$4.68M<0.01%+4,66013F-HRTimelineGroup
Rock Springs Capital Management LP99,429$3.99M0.23%013F-HRTimeline
Rhenman & Partners Asset Management AB87,500$3.51M0.43%new13F-HRTimeline
TD Asset Management Inc82,996$3.33M<0.01%-30,35613F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC81,974$3.29M<0.01%-19,66913F-HR/ATimelineGroup
FMR LLCin group FMR LLC81,395$3.26M<0.01%+81,01113F-HRTimelineGroup
Driehaus Capital Management LLC76,633$3.07M0.02%-7,21713F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …64,458$2.58M<0.01%-4,96613F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/50,870$2.04M<0.01%+7,30313F-HRTimelineGroup
Integral Health Asset Management, LLC50,000$2M0.11%new13F-HRTimeline
SEVEN GRAND MANAGERS, LLC50,000$2M0.13%013F-HRTimeline
Ishara Investments LP49,200$1.97M1.99%new13F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…48,419$1.94M<0.01%+26,47813F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…46,079$1.85M<0.01%+7,73213F-HRTimelineGroup
Qube Research & Technologies Ltd42,242$1.69M<0.01%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS40,570$1.63M<0.01%+38,30613F-HRTimelineGroup
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…39,417$1.58M0.19%-2,04313F-HRTimelineGroup
ALPS ADVISORS INCin group ALPS ADVISORS INC36,628$1.47M0.01%-2013F-HRTimelineGroup
STEMPOINT CAPITAL LP36,540$1.46M0.28%new13F-HR/ATimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp33,778$1.35M<0.01%-1,35613F-HRTimelineGroup
POLEN CAPITAL MANAGEMENT LLC26,775$1.07M0.01%-4,48313F-HRTimeline
Maven Securities LTDin group Maven Securities LTD25,000$1M0.06%new13F-HRTimelineGroup
Nuveen, LLCin group TIAA23,734$951K<0.01%013F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd23,551$944K0.02%+18,62513F-HRTimelineGroup
Rafferty Asset Management, LLC22,137$887K<0.01%-2,55313F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC18,385$737K<0.01%-29,78713F-HRTimelineGroup
RHUMBLINE ADVISERS18,308$734K<0.01%+61413F-HRTimeline
CITIGROUP INCin group CITIGROUP INC18,058$724K<0.01%+12,87313F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.16,410$675K<0.01%+79013F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC15,217$610K<0.01%-1,14313F-HRTimelineGroup
Walleye Capital LLCin group Walleye Capital LLC15,097$605K<0.01%new13F-HR/ATimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\13,249$531K<0.01%+3,22013F-HRTimelineGroup
Longaeva Partners L.P.12,693$509K0.02%-67,03613F-HRTimeline
KENNEDY CAPITAL MANAGEMENT LLC12,284$492K0.01%+5,53213F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding11,513$456K+429Timeline
Invesco Ltd.in group Invesco Ltd.10,787$432K<0.01%-100,37513F-HRTimelineGroup
PROFUND ADVISORS LLC9,939$398K0.01%+72613F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…8,565$343K<0.01%013F-HRTimelineGroup
China Universal Asset Management Co., L…7,920$318K0.02%-2,35213F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…7,310$293K<0.01%new13F-HRTimelineGroup
ExodusPoint Capital Management, LP7,190$288K<0.01%new13F-HRTimeline
VARCOV Co.6,571$263K0.1%new13F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…6,374$256K0.07%+15413F-HRTimelineGroup
Quarry LP6,304$253K0.05%new13F-HRTimeline
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…6,180$248K<0.01%new13F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN5,894$236K<0.01%-11,65713F-HR/ATimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP5,500$220K<0.01%-90013F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC5,489$220K<0.01%-2,10013F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND5,300$212K<0.01%013F-HRTimeline
AlphaCentric Advisors LLC4,818$193K0.19%+2,09813F-HRTimeline
Police & Firemen's Retirement System of…4,232$170K<0.01%013F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC4,116$165K<0.01%-1,07313F-HRTimeline
Cygnus Capital Advisors, LLC3,800$152K0.1%+1,40013F-HRTimeline
STRS OHIO2,900$116K<0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…2,352$94.3K<0.01%+1,22313F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc1,432$57.4K<0.01%-25013F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…1,302$52.2K<0.01%013F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.1,003$40.2K<0.01%+12713F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…868$34.8K<0.01%-12013F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…371$14.9K<0.01%new13F-HRTimeline
Steward Partners Investment Advisory, L…254$10.2K<0.01%new13F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…241$9.66K<0.01%+19313F-HRTimelineGroup
GAMMA Investing LLC238$9.54K<0.01%+6113F-HRTimeline
Farther Finance Advisors, LLC196$8.1K<0.01%+613F-HRTimeline
Quantbot Technologies LP178$7.14K<0.01%new13F-HRTimeline
Sterling Capital Management LLC105$4.21K<0.01%013F-HRTimeline
CWM, LLCin group CWM, LLC67$2.69K<0.01%-1313F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\51$2.04K<0.01%-1413F-HRTimelineGroup
Caitong International Asset Management …36$1.44K<0.01%new13F-HRTimeline
Allworth Financial LP29$1.16K<0.01%+113F-HRTimeline
Hughes Financial Services, LLC26$1.04K<0.01%+113F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA30$1K<0.01%-45913F-HRTimelineGroup
SIGNATUREFD, LLC24$962<0.01%new13F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…23$922<0.01%+313F-HR/ATimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…16$641<0.01%+1113F-HRTimelineGroup
Fortitude Family Office, LLC15$601<0.01%new13F-HRTimeline
Root Financial Partners, LLC10$401<0.01%new13F-HRTimeline
MAI Capital Management2$81<0.01%new13F-HRTimeline
ROTHSCHILD INVESTMENT LLC1$40<0.01%013F-HRTimeline
Covestor Ltd3$00%new13F-HRTimelineValue filed as zero, left out of ratios.