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Disclosery

SION SIONNA THERAPEUTICS INC

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COMMON STOCK (common), issuer CIK 2036042

66 managers (66 13F filers) reported a position in SION shares at 2025-06-30, 43,448,395 shares in all. 26 filers opened a position and 8 filers sold out during the quarter.

Managers
66
13F filers
66
New
26
Added
18
Reduced
10
Sold out
8
Shares held by filers
43,448,395

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2025

Filers in the available 13F reports with a share position at 2025-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.10,445,322$181M3.05%013F-HRTimelineGroup
TPG GP A, LLCin group TPG GP A, LLC6,744,962$117M6.24%+60,00013F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC3,704,959$64.3M1.62%013F-HRTimelineGroup
Atlas Venture Life Science Advisors, LLC3,694,020$64.1M9.68%013F-HRTimeline
VIKING GLOBAL INVESTORS LPin group VIKING GLOBAL INVESTORS LP3,195,181$55.4M0.16%+242,42713F-HRTimelineGroup
ENAVATE SCIENCES GP, LLC2,478,030$43M24.35%013F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO2,221,188$38.5M<0.01%+51,58913F-HRTimelineGroup
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC1,216,045$21.1M0.79%-35,05613F-HRTimelineGroup
BRAIDWELL LP1,081,855$18.8M0.64%new13F-HRTimeline
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…970,590$16.8M0.31%+223,59013F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc950,547$16.5M0.03%+204,58313F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/861,238$14.9M<0.01%-134,97413F-HRTimeline
JENNISON ASSOCIATES LLC752,800$13.1M0.01%-107,12713F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.637,104$11.1M<0.01%+438,70813F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC630,351$10.9M<0.01%+84,18413F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources500,023$8.68M<0.01%013F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP400,000$6.94M0.07%013F-HRTimelineGroup
Soleus Capital Management, L.P.376,000$6.52M0.45%+136,00013F-HRTimeline
Siren, L.L.C.in group Siren, L.L.C.325,000$5.64M0.29%013F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC289,275$5.02M<0.01%+153,71213F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC236,813$4.11M<0.01%+27,54713F-HRTimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.186,222$3.23M0.01%013F-HRTimelineGroup
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…186,015$3.23M0.66%+71,87713F-HRTimelineGroup
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC135,185$2.35M<0.01%+72,18513F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC129,912$2.25M<0.01%-196,58813F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP124,518$2.16M<0.01%+110,11813F-HRTimelineGroup
Rock Springs Capital Management LP99,429$1.73M0.11%013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co92,832$1.61M<0.01%+28,18813F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP91,890$1.59M<0.01%+65,06813F-HRTimelineGroup
Driehaus Capital Management LLC83,850$1.45M0.01%-245,03913F-HRTimeline
Woodline Partners LP80,000$1.39M0.01%013F-HRTimeline
UBS Group AGin group UBS Group AG51,367$891K<0.01%+40,22113F-HRTimelineGroup
Holocene Advisors, LP50,000$868K<0.01%013F-HRTimeline
TD Asset Management Inc49,966$867K<0.01%-5,40013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC46,048$799K<0.01%-17,69313F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY44,018$764K<0.01%+40,07913F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …38,038$660K<0.01%+4,48913F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC26,000$451K<0.01%new13F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp24,131$419K<0.01%new13F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC23,022$399K<0.01%new13F-HR/ATimelineGroup
RHUMBLINE ADVISERS17,670$307K<0.01%new13F-HRTimeline
POLEN CAPITAL MANAGEMENT LLC16,975$295K<0.01%new13F-HRTimeline
BANTAMAC CAPITAL, LLC16,975$295K0.11%new13F-HRTimeline
Nuveen, LLCin group TIAA16,040$278K<0.01%new13F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…14,834$257K<0.01%new13F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC14,034$243K<0.01%-165,03813F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC14,017$243K<0.01%new13F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\9,596$166K<0.01%new13F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…8,033$139K<0.01%new13F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND6,800$118K<0.01%new13F-HR/ATimeline
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…6,747$117K<0.01%new13F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN6,374$111K<0.01%new13F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/6,012$104K<0.01%-2,72713F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…5,535$96K0.03%new13F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC4,380$76K<0.01%new13F-HRTimelineGroup
Police & Firemen's Retirement System of…2,608$45.2K<0.01%new13F-HRTimeline
STRS OHIO2,300$39.9K<0.01%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS1,761$30.6K<0.01%new13F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc1,374$23.8K<0.01%new13F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…1,259$21.8K<0.01%new13F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…770$13.4K<0.01%new13F-HRTimeline
AMALGAMATED BANK421$7K<0.01%new13F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA60$1K<0.01%-55813F-HR/ATimelineGroup
Hughes Financial Services, LLC44$747<0.01%new13F-HRTimeline
Sterling Capital Management LLC30$521<0.01%new13F-HR/ATimeline
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.