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Disclosery

SEPN SEPTERNA INC

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Stock (common), issuer CIK 1984086

89 managers (90 13F filers) reported a position in SEPN shares at 2025-06-30, 44,430,474 shares in all. 25 filers opened a position and 6 filers sold out during the quarter.

Managers
89
13F filers
90
New
25
Added
31
Reduced
19
Sold out
6
Shares held by filers
44,430,474

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2025

Filers in the available 13F reports with a share position at 2025-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.6,995,858$73.9M1.25%013F-HRTimelineGroup
TRV GP V, LLC6,215,591$65.7M39.66%013F-HRTimeline
Driehaus Capital Management LLC4,680,431$49.5M0.4%+1,557,82313F-HRTimeline
BVF INC/ILin group BVF INC/IL4,396,124$46.5M1.66%013F-HRTimelineGroup
TRV GP VI, LLC4,211,659$44.5M69.32%013F-HRTimeline
SAMSARA BIOCAPITAL, LLC3,149,128$33.3M6.81%013F-HRTimeline
Siren, L.L.C.in group Siren, L.L.C.2,202,514$23.3M1.2%013F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC1,416,314$15M<0.01%-33,08513F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC1,414,363$14.9M<0.01%+419,31913F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.1,390,800$14.7M<0.01%+132,48713F-HRTimelineGroup
Avoro Capital Advisors LLC1,237,500$13.1M0.23%-100,00013F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC847,227$8.96M1.45%+126,37913F-HRTimelineGroup
Checkpoint Capital L.P.586,473$6.2M2.89%-238,40513F-HRTimeline
Sio Capital Management, LLC584,435$6.18M2.48%-204,23513F-HRTimeline
Casdin Capital, LLC553,268$5.85M0.53%013F-HRTimeline
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC541,450$5.72M0.21%new13F-HRTimelineGroup
Venrock Adviser, LLC540,453$5.71M0.43%new13F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC487,956$5.16M<0.01%+78,31613F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP369,992$3.91M<0.01%+25,38813F-HRTimelineGroup
Catalio Capital Management, LP294,360$3.11M0.65%-729,88513F-HRTimeline
Woodline Partners LP282,585$2.99M0.02%-300,00013F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …222,702$2.35M<0.01%+119,95313F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…166,506$1.76M<0.01%+141,29713F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co154,781$1.64M<0.01%+36,33013F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP154,344$1.63M<0.01%-3,69613F-HRTimelineGroup
Deep Track Capital, LP121,716$1.29M0.04%-1,791,21313F-HRTimeline
Logos Global Management LP109,202$1.15M0.15%-25,00013F-HRTimeline
UBS Group AGgroup of 2 filers holding101,035$1.07M-138,895Timeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/99,213$1.05M<0.01%+87,65413F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY84,860$897K<0.01%-6,18413F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP77,642$821K<0.01%+2,80113F-HRTimelineGroup
Soleus Capital Management, L.P.75,456$798K0.06%-675,89713F-HRTimeline
Rangeley Capital, LLC58,605$619K0.78%+5,65513F-HRTimeline
Nuveen, LLCin group TIAA57,971$613K<0.01%+34,01013F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC51,944$549K<0.01%-384,62013F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp48,489$513K<0.01%+10,11313F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC35,706$377K<0.01%+12,97313F-HR/ATimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.35,000$370K<0.01%013F-HRTimelineGroup
RHUMBLINE ADVISERS28,572$302K<0.01%+5,25413F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/24,902$264K<0.01%+1,94513F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC24,142$255K0.01%new13F-HRTimeline
GSA CAPITAL PARTNERS LLP23,527$249K0.02%+5,22813F-HRTimeline
SIMPLEX TRADING, LLC23,525$248K0.01%+23,49513F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd22,330$236K0.01%-15,02013F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.22,100$234K<0.01%new13F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC17,774$188K<0.01%new13F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL16,761$177K<0.01%new13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN14,717$156K<0.01%+3,84813F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…13,685$145K<0.01%new13F-HRTimelineGroup
CW Advisors, LLC12,589$133K<0.01%new13F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC12,200$129K<0.01%new13F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\12,123$128K<0.01%-3,84513F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.11,833$125K<0.01%-36913F-HRTimelineGroup
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…11,697$124K<0.01%+71013F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC10,737$113K<0.01%new13F-HR/ATimelineGroup
Quadrature Capital Ltdin group Quadrature Capital Ltd10,125$107K<0.01%new13F-HRTimelineGroup
PharVision Advisers, LLC10,152$107K0.15%new13F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO10,101$107K<0.01%+1,31513F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC7,173$75.8K<0.01%-30,88213F-HRTimelineGroup
Quarry LP3,601$38.1K0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…3,555$37.6K<0.01%013F-HRTimeline
STRS OHIO3,400$35.9K<0.01%013F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND2,900$30.7K<0.01%013F-HR/ATimeline
FMR LLCin group FMR LLC2,485$26.3K<0.01%-47,29313F-HRTimelineGroup
Covestor Ltd2,324$24K0.01%+2,31813F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…2,225$23.5K<0.01%+43713F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS2,210$23.4K<0.01%+1,06113F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc1,945$20.6K<0.01%+10513F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…1,944$20.5K<0.01%013F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA1,840$19K<0.01%+1,03813F-HR/ATimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…1,370$14.5K<0.01%-42,99213F-HRTimeline
SIGNATUREFD, LLC966$10.2K<0.01%new13F-HRTimeline
CWM, LLCin group CWM, LLC872$9K<0.01%+59013F-HRTimelineGroup
GROUP ONE TRADING LLC789$8.34K<0.01%new13F-HRTimeline
AMALGAMATED BANK634$7K<0.01%013F-HRTimeline
Caitong International Asset Management …605$6.39K<0.01%new13F-HRTimeline
Sterling Capital Management LLC577$6.1K<0.01%+42013F-HR/ATimeline
GAMMA Investing LLC577$6.1K<0.01%+14313F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\265$2.8K<0.01%new13F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC222$2.35K<0.01%new13F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.214$2.26K<0.01%new13F-HR/ATimelineGroup
COMERICA BANK212$2.24K<0.01%new13F-HRTimeline
NISA INVESTMENT ADVISORS, LLC143$1.51K<0.01%+913F-HRTimeline
Fortitude Family Office, LLC71$750<0.01%new13F-HRTimeline
SBI Securities Co., Ltd.50$529<0.01%new13F-HRTimeline
ROTHSCHILD INVESTMENT LLC30$317<0.01%new13F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…22$233<0.01%new13F-HRTimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/8$85<0.01%013F-HR/ATimelineGroup
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.