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Disclosery

SEPN SEPTERNA INC

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Stock (common), issuer CIK 1984086

72 managers (72 13F filers) reported a position in SEPN shares at 2025-03-31, 45,290,478 shares in all. 19 filers opened a position and 19 filers sold out during the quarter.

Managers
72
13F filers
72
New
19
Added
25
Reduced
12
Sold out
19
Shares held by filers
45,290,478

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2025

Filers in the available 13F reports with a share position at 2025-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.6,995,858$40.5M0.68%013F-HRTimelineGroup
TRV GP V, LLC6,215,591$36M28.77%013F-HRTimeline
BVF INC/ILin group BVF INC/IL4,396,124$25.5M1.04%+1,944,10013F-HRTimelineGroup
TRV GP VI, LLC4,211,659$24.4M58.1%+1,059,20313F-HRTimeline
SAMSARA BIOCAPITAL, LLC3,149,128$18.2M3.25%+380,60813F-HRTimeline
Driehaus Capital Management LLC3,122,608$18.1M0.17%+533,05513F-HRTimeline
Siren, L.L.C.in group Siren, L.L.C.2,202,514$12.8M0.72%013F-HR/ATimelineGroup
Deep Track Capital, LP1,912,929$11.1M0.36%013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC1,449,399$8.39M<0.01%-224,95813F-HR/ATimelineGroup
Avoro Capital Advisors LLC1,337,500$7.74M0.12%+227,50013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.1,258,313$7.29M<0.01%-418,82213F-HRTimelineGroup
Catalio Capital Management, LP1,024,245$5.93M1.47%013F-HRTimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC995,044$5.76M<0.01%+10,01213F-HRTimelineGroup
Checkpoint Capital L.P.824,878$4.78M2.62%new13F-HRTimeline
Sio Capital Management, LLC788,670$4.57M1.38%+516,98313F-HRTimeline
Soleus Capital Management, L.P.751,353$4.35M0.34%+75,94413F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC720,848$4.17M0.8%new13F-HRTimelineGroup
Woodline Partners LP582,585$3.37M0.02%+282,58513F-HRTimeline
Casdin Capital, LLC553,268$3.2M0.26%013F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC436,564$2.53M<0.01%new13F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC409,640$2.37M<0.01%+29,06313F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP344,604$2M<0.01%+71,82813F-HRTimelineGroup
UBS Group AGin group UBS Group AG239,930$1.39M<0.01%+131,47713F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP158,040$915K<0.01%+10,26413F-HRTimelineGroup
Logos Global Management LP134,202$777K0.14%013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co118,451$686K<0.01%-21,16513F-HR/ATimelineGroup
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …102,749$595K<0.01%013F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY91,044$527K<0.01%+49,13313F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP74,841$433K<0.01%new13F-HRTimelineGroup
Stonepine Capital Management, LLC68,084$394K0.38%new13F-HRTimeline
Rangeley Capital, LLC52,950$307K0.35%new13F-HRTimeline
FMR LLCin group FMR LLC49,778$288K<0.01%-953,18013F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…44,362$257K<0.01%+42,99213F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp38,376$222K<0.01%+28313F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC38,055$220K<0.01%+23,42213F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd37,350$216K0.01%new13F-HRTimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.35,000$203K<0.01%013F-HRTimelineGroup
Swiss National Bank30,100$174K<0.01%new13F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…25,209$146K<0.01%new13F-HRTimelineGroup
Nuveen, LLCin group TIAA23,961$139K<0.01%13F-HRTimelineGroup
RHUMBLINE ADVISERS23,318$135K<0.01%+3,32313F-HR/ATimeline
PRICE T ROWE ASSOCIATES INC /MD/22,957$133K<0.01%-495,63113F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC22,733$132K<0.01%-6,05213F-HR/ATimelineGroup
Lindbrook Capital, LLC21,000$122K0.01%013F-HRTimeline
STONERIDGE INVESTMENT PARTNERS LLC18,477$107K0.09%new13F-HRTimeline
GSA CAPITAL PARTNERS LLP18,299$106K0.01%new13F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\15,968$92.5K<0.01%+5,54913F-HRTimelineGroup
Chicago Partners Investment Group LLC10,954$77.2K<0.01%new13F-HRTimeline
Invesco Ltd.in group Invesco Ltd.12,202$70.6K<0.01%+4813F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/11,559$66.9K<0.01%-67,18513F-HRTimelineGroup
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…10,987$63.6K<0.01%+46813F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN10,869$62.9K<0.01%+21813F-HRTimelineGroup
Corebridge Financial, Inc.in group Corebridge Financial, Inc.9,102$52.7K<0.01%-13413F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO8,786$50.9K<0.01%-29,22913F-HRTimelineGroup
KLP KAPITALFORVALTNING AS8,400$48.6K<0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…3,555$20.6K<0.01%new13F-HRTimeline
STRS OHIO3,400$19.7K<0.01%013F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND2,900$16.8K<0.01%+1,50013F-HR/ATimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…1,944$11.3K<0.01%013F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc1,840$10.7K<0.01%013F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,788$10.4K<0.01%+69513F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS1,149$6.65K<0.01%-1,10213F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA802$4K<0.01%-59613F-HR/ATimelineGroup
AMALGAMATED BANK634$4K<0.01%013F-HRTimeline
GAMMA Investing LLC434$2.51K<0.01%+41913F-HR/ATimeline
CWM, LLCin group CWM, LLC282$2K<0.01%new13F-HRTimelineGroup
Sterling Capital Management LLC157$909<0.01%-10913F-HRTimeline
NISA INVESTMENT ADVISORS, LLC134$776<0.01%new13F-HRTimeline
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/8$46<0.01%new13F-HRTimelineGroup
SIMPLEX TRADING, LLC30$00%new13F-HRTimelineValue filed as zero, left out of ratios.
Covestor Ltd6$00%new13F-HRTimelineValue filed as zero, left out of ratios.
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.